{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:56:06Z","timestamp":1791190566612,"version":"4.1.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100012905","name":"Department of Science and Technology of Shandong Province","doi-asserted-by":"publisher","award":["One Case One Policy"],"award-info":[{"award-number":["One Case One Policy"]}],"id":[{"id":"10.13039\/100012905","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["GeroScience"],"DOI":"10.1007\/s11357-025-02077-8","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:46:05Z","timestamp":1768556765000},"page":"7887-7903","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metacontrol-related aperiodic and periodic neural activity in cognitive\u00a0aging: enhancing the neural signal-to-noise ratio\u00a0through anodal transcranial direct current stimulation"],"prefix":"10.1007","volume":"48","author":[{"given":"Yu","family":"Pi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhui","family":"Lyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Beste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Colzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4731-5125","authenticated-orcid":false,"given":"Bernhard","family":"Hommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"2077_CR1","doi-asserted-by":"publisher","first-page":"e068208","DOI":"10.1136\/bmj-2021-068208","volume":"376","author":"S Tyrovolas","year":"2022","unstructured":"Tyrovolas S, Stergachis A, Krish VS, et al. Global, regional, and national burden of diseases and injuries for adults 70 years and older: Systematic analysis for the global burden of disease 2019 study. BMJ-Br Med J. 2022;376:e068208. https:\/\/doi.org\/10.1136\/bmj-2021-068208.","journal-title":"BMJ-Br Med J"},{"key":"2077_CR2","doi-asserted-by":"publisher","unstructured":"Diamond A. Executive functions. In: Fiske ST, editor. Annu. Rev. Psychol. Vol. 64, Palo Alto: Annual Reviews; 2013. p. 135\u201368. https:\/\/doi.org\/10.1146\/annurev-psych-113011-143750.","DOI":"10.1146\/annurev-psych-113011-143750"},{"key":"2077_CR3","doi-asserted-by":"publisher","unstructured":"Verhaeghen P, Cerella J, Bopp KL, et al. Aging and varieties of cognitive control: A review of meta-analyses on resistance to interference, coordination, and task switching, and an experimental exploration of age-sensitivity in the newly identified process of focus switching. Cogn. Limit. Aging Psychopathol, New York, NY, US: Cambridge University Press; 2005. p. 160\u201389. https:\/\/doi.org\/10.1017\/CBO9780511720413.008.","DOI":"10.1017\/CBO9780511720413.008"},{"key":"2077_CR4","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/S0149-7634(02)00071-4","volume":"26","author":"P Verhaeghen","year":"2002","unstructured":"Verhaeghen P, Cerella J. Aging, executive control, and attention: a review of meta-analyses. Neurosci Biobehav Rev. 2002;26:849\u201357. https:\/\/doi.org\/10.1016\/S0149-7634(02)00071-4.","journal-title":"Neurosci Biobehav Rev"},{"key":"2077_CR5","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.brs.2016.06.004","volume":"9","author":"M Bikson","year":"2016","unstructured":"Bikson M, Grossman P, Thomas C, et al. Safety of transcranial direct current stimulation: evidence based update 2016. Brain Stimulat. 2016;9:641\u201361. https:\/\/doi.org\/10.1016\/j.brs.2016.06.004.","journal-title":"Brain Stimulat"},{"key":"2077_CR6","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.brainresbull.2007.01.004","volume":"72","author":"C Poreisz","year":"2007","unstructured":"Poreisz C, Boros K, Antal A, et al. Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients. Brain Res Bull. 2007;72:208\u201314. https:\/\/doi.org\/10.1016\/j.brainresbull.2007.01.004.","journal-title":"Brain Res Bull"},{"key":"2077_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3758\/s13414-016-1224-2","volume":"79","author":"RMG Reinhart","year":"2017","unstructured":"Reinhart RMG, Cosman JD, Fukuda K, et al. Using transcranial direct-current stimulation (tDCS) to understand cognitive processing. Atten Percept Psychophys. 2017;79:3\u201323. https:\/\/doi.org\/10.3758\/s13414-016-1224-2.","journal-title":"Atten Percept Psychophys"},{"key":"2077_CR8","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jneumeth.2016.12.008","volume":"277","author":"C Lee","year":"2017","unstructured":"Lee C, Jung Y-J, Lee SJ, et al. COMETS2: an advanced MATLAB toolbox for the numerical analysis of electric fields generated by transcranial direct current stimulation. J Neurosci Methods. 2017;277:56\u201362. https:\/\/doi.org\/10.1016\/j.jneumeth.2016.12.008.","journal-title":"J Neurosci Methods"},{"key":"2077_CR9","doi-asserted-by":"publisher","first-page":"3380","DOI":"10.1162\/jocn_a_00020","volume":"23","author":"L Jacobson","year":"2011","unstructured":"Jacobson L, Javitt DC, Lavidor M. Activation of inhibition: diminishing impulsive behavior by direct current stimulation over the inferior frontal gyrus. J Cogn Neurosci. 2011;23:3380\u20137. https:\/\/doi.org\/10.1162\/jocn_a_00020.","journal-title":"J Cogn Neurosci"},{"key":"2077_CR10","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyae023","volume":"27","author":"AH Koyun","year":"2024","unstructured":"Koyun AH, Wendiggensen P, Roessner V, et al. Effects of catecholaminergic and transcranial direct current stimulation on response inhibition. Int J Neuropsychopharmacol. 2024;27:pyae023. https:\/\/doi.org\/10.1093\/ijnp\/pyae023.","journal-title":"Int J Neuropsychopharmacol"},{"key":"2077_CR11","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.nlm.2017.07.005","volume":"144","author":"DF Stramaccia","year":"2017","unstructured":"Stramaccia DF, Penolazzi B, Altoe G, et al. TDCS over the right inferior frontal gyrus disrupts control of interference in memory: a retrieval-induced forgetting study. Neurobiol Learn Mem. 2017;144:114\u201330. https:\/\/doi.org\/10.1016\/j.nlm.2017.07.005.","journal-title":"Neurobiol Learn Mem"},{"key":"2077_CR12","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1007\/s00429-019-01839-3","volume":"224","author":"N Adelhoefer","year":"2019","unstructured":"Adelhoefer N, Mueckschel M, Teufert B, et al. Anodal tDCS affects neuromodulatory effects of the norepinephrine system on superior frontal theta activity during response inhibition. Brain Struct Funct. 2019;224:1291\u2013300. https:\/\/doi.org\/10.1007\/s00429-019-01839-3.","journal-title":"Brain Struct Funct"},{"key":"2077_CR13","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1109\/TAU.1967.1161901","volume":"15","author":"PD Welch","year":"1967","unstructured":"Welch PD. The use of fast Fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodograms. IEEE Trans Audio Electroacoust. 1967;15:70\u20133. https:\/\/doi.org\/10.1109\/TAU.1967.1161901.","journal-title":"IEEE Trans Audio Electroacoust"},{"key":"2077_CR14","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1038\/s41593-020-00744-x","volume":"23","author":"T Donoghue","year":"2020","unstructured":"Donoghue T, Haller M, Peterson EJ, et al. Parameterizing neural power spectra into periodic and aperiodic components. Nat Neurosci. 2020;23:1655\u201365. https:\/\/doi.org\/10.1038\/s41593-020-00744-x.","journal-title":"Nat Neurosci"},{"key":"2077_CR15","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.brs.2025.03.024","volume":"18","author":"Y Gao","year":"2025","unstructured":"Gao Y, Koyun AH, Roessner V, et al. Transcranial direct current stimulation and methylphenidate interact to increase cognitive persistence as a core component of metacontrol: evidence from aperiodic activity analyses. Brain Stimulat. 2025;18:720\u20139. https:\/\/doi.org\/10.1016\/j.brs.2025.03.024.","journal-title":"Brain Stimulat"},{"key":"2077_CR16","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyae033","volume":"27","author":"Y Gao","year":"2024","unstructured":"Gao Y, Roessner V, Stock A-K, et al. Catecholaminergic modulation of metacontrol is reflected by changes in aperiodic EEG activity. Int J Neuropsychopharmacol. 2024;27:pyae033. https:\/\/doi.org\/10.1093\/ijnp\/pyae033.","journal-title":"Int J Neuropsychopharmacol"},{"key":"2077_CR17","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.14576","author":"Y Pi","year":"2024","unstructured":"Pi Y, Yan J, Pscherer C, et al. Interindividual aperiodic resting-state EEG activity predicts cognitive-control styles. Psychophysiology. 2024. https:\/\/doi.org\/10.1111\/psyp.14576.","journal-title":"Psychophysiology"},{"key":"2077_CR18","doi-asserted-by":"publisher","first-page":"24088","DOI":"10.1038\/s41598-024-74867-7","volume":"14","author":"J Yan","year":"2024","unstructured":"Yan J, Yu S, Muckschel M, et al. Aperiodic neural activity reflects metacontrol in task-switching. Sci Rep. 2024;14:24088. https:\/\/doi.org\/10.1038\/s41598-024-74867-7.","journal-title":"Sci Rep"},{"key":"2077_CR19","doi-asserted-by":"publisher","first-page":"7941","DOI":"10.1093\/cercor\/bhad089","volume":"33","author":"C Zhang","year":"2023","unstructured":"Zhang C, Stock A-K, M\u00fcckschel M, et al. Aperiodic neural activity reflects metacontrol. Cereb Cortex. 2023;33:7941\u201351. https:\/\/doi.org\/10.1093\/cercor\/bhad089.","journal-title":"Cereb Cortex"},{"key":"2077_CR20","doi-asserted-by":"publisher","first-page":"18349","DOI":"10.1038\/s41598-025-00736-6","volume":"15","author":"Y Pi","year":"2025","unstructured":"Pi Y, Pscherer C, Muckschel M, et al. Metacontrol-related aperiodic neural activity decreases but strategic adjustment thereof increases from childhood to adulthood. Sci Rep. 2025;15:18349. https:\/\/doi.org\/10.1038\/s41598-025-00736-6.","journal-title":"Sci Rep"},{"key":"2077_CR21","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1097\/WNR.0000000000002156","volume":"36","author":"J Yan","year":"2025","unstructured":"Yan J, Colzato L, Hommel B. Code conflict in an event file task is reflected by aperiodic neural activity. NeuroReport. 2025;36:337\u201341. https:\/\/doi.org\/10.1097\/WNR.0000000000002156.","journal-title":"NeuroReport"},{"key":"2077_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2025.106297","volume":"176","author":"L Colzato","year":"2025","unstructured":"Colzato L, Zhang H, Roessner V, et al. Non-bivalent psychopathology: rethinking mental disorders through metacontrol. Neurosci Biobehav Rev. 2025;176:106297. https:\/\/doi.org\/10.1016\/j.neubiorev.2025.106297.","journal-title":"Neurosci Biobehav Rev"},{"key":"2077_CR23","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.70148","volume":"62","author":"H Zhang","year":"2025","unstructured":"Zhang H, Konjusha A, Yu S, et al. The dynamic management of working memory is supported by aperiodic neural activity. Psychophysiology. 2025;62:e70148. https:\/\/doi.org\/10.1111\/psyp.70148.","journal-title":"Psychophysiology"},{"key":"2077_CR24","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1016\/j.biopsych.2015.04.016","volume":"77","author":"B Voytek","year":"2015","unstructured":"Voytek B, Knight RT. Dynamic network communication as a unifying neural basis for cognition, development, aging, and disease. Biol Psychiatry. 2015;77:1089\u201397. https:\/\/doi.org\/10.1016\/j.biopsych.2015.04.016.","journal-title":"Biol Psychiatry"},{"key":"2077_CR25","doi-asserted-by":"publisher","unstructured":"Krause B, Cohen Kadosh R. Not all brains are created equal: The relevance of individual differences in responsiveness to transcranial electrical stimulation. Front Syst Neurosci 2014;8. https:\/\/doi.org\/10.3389\/fnsys.2014.00025.","DOI":"10.3389\/fnsys.2014.00025"},{"key":"2077_CR26","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00181","volume":"9","author":"LM Li","year":"2015","unstructured":"Li LM, Uehara K, Hanakawa T. The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies. Front Cell Neurosci. 2015;9:181. https:\/\/doi.org\/10.3389\/fncel.2015.00181.","journal-title":"Front Cell Neurosci"},{"key":"2077_CR27","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.tics.2012.10.007","volume":"16","author":"W Klimesch","year":"2012","unstructured":"Klimesch W. Alpha-band oscillations, attention, and controlled access to stored information. Trends Cogn Sci. 2012;16:606\u201317. https:\/\/doi.org\/10.1016\/j.tics.2012.10.007.","journal-title":"Trends Cogn Sci"},{"key":"2077_CR28","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.neuroimage.2013.05.117","volume":"85","author":"M-F Kuo","year":"2014","unstructured":"Kuo M-F, Paulus W, Nitsche MA. Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases. Neuroimage. 2014;85:948\u201360. https:\/\/doi.org\/10.1016\/j.neuroimage.2013.05.117.","journal-title":"Neuroimage"},{"key":"2077_CR29","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.08789","volume":"4","author":"V Bachtiar","year":"2015","unstructured":"Bachtiar V, Near J, Johansen-Berg H, et al. Modulation of GABA and resting state functional connectivity by transcranial direct current stimulation. Elife. 2015;4:e08789. https:\/\/doi.org\/10.7554\/eLife.08789.","journal-title":"Elife"},{"key":"2077_CR30","doi-asserted-by":"publisher","first-page":"4065","DOI":"10.1523\/JNEUROSCI.0079-17.2017","volume":"37","author":"D Antonenko","year":"2017","unstructured":"Antonenko D, Schubert F, Bohm F, et al. TDCS-induced modulation of GABA levels and resting-state functional connectivity in older adults. J Neurosci. 2017;37:4065\u201373. https:\/\/doi.org\/10.1523\/JNEUROSCI.0079-17.2017.","journal-title":"J Neurosci"},{"key":"2077_CR31","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1523\/JNEUROSCI.2524-18.2018","volume":"39","author":"T Inoue","year":"2019","unstructured":"Inoue T, Taneda K. Transcranial direct current stimulation modulates GABA levels beyond the stimulated region: perspectives for stroke rehabilitation. J Neurosci. 2019;39:1768\u201370. https:\/\/doi.org\/10.1523\/JNEUROSCI.2524-18.2018.","journal-title":"J Neurosci"},{"key":"2077_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2022.101076","volume":"54","author":"AT Hill","year":"2022","unstructured":"Hill AT, Clark GM, Bigelow FJ, et al. Periodic and aperiodic neural activity displays age-dependent changes across early-to-middle childhood. Dev Cogn Neurosci. 2022;54:101076. https:\/\/doi.org\/10.1016\/j.dcn.2022.101076.","journal-title":"Dev Cogn Neurosci"},{"key":"2077_CR33","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jneumeth.2007.03.024","volume":"164","author":"E Maris","year":"2007","unstructured":"Maris E, Oostenveld R. Nonparametric statistical testing of EEG- and MEG-data. J Neurosci Methods. 2007;164:177\u201390. https:\/\/doi.org\/10.1016\/j.jneumeth.2007.03.024.","journal-title":"J Neurosci Methods"},{"key":"2077_CR34","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.neuroimage.2017.06.078","volume":"158","author":"R Gao","year":"2017","unstructured":"Gao R, Peterson EJ, Voytek B. Inferring synaptic excitation\/inhibition balance from field potentials. Neuroimage. 2017;158:70\u20138. https:\/\/doi.org\/10.1016\/j.neuroimage.2017.06.078.","journal-title":"Neuroimage"},{"key":"2077_CR35","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.70068","volume":"10","author":"L Waschke","year":"2021","unstructured":"Waschke L, Donoghue T, Fiedler L, et al. Modality-specific tracking of attention and sensory statistics in the human electrophysiological spectral exponent. Elife. 2021;10:e70068. https:\/\/doi.org\/10.7554\/eLife.70068.","journal-title":"Elife"},{"key":"2077_CR36","doi-asserted-by":"publisher","first-page":"016037","DOI":"10.1088\/1741-2552\/ada980","volume":"22","author":"DH Liu","year":"2025","unstructured":"Liu DH, Kumar S, Alawieh H, et al. Personalized \u00b5-transcranial alternating current stimulation improves online brain\u2013computer interface control. J Neural Eng. 2025;22:016037. https:\/\/doi.org\/10.1088\/1741-2552\/ada980.","journal-title":"J Neural Eng"},{"key":"2077_CR37","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.brs.2015.01.400","volume":"8","author":"JC Horvath","year":"2015","unstructured":"Horvath JC, Forte JD, Carter O. Quantitative review finds no evidence of cognitive effects in healthy populations from single-session transcranial direct current stimulation (tDCS). Brain Stimulat. 2015;8:535\u201350. https:\/\/doi.org\/10.1016\/j.brs.2015.01.400.","journal-title":"Brain Stimulat"},{"key":"2077_CR38","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1177\/0956797617698139","volume":"28","author":"J Nilsson","year":"2017","unstructured":"Nilsson J, Lebedev AV, Rydstrom A, et al. Direct-current stimulation does little to improve the outcome of working memory training in older adults. Psychol Sci. 2017;28:907\u201320. https:\/\/doi.org\/10.1177\/0956797617698139.","journal-title":"Psychol Sci"},{"key":"2077_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2022.108261","volume":"168","author":"A Pathania","year":"2022","unstructured":"Pathania A, Euler MJ, Clark M, et al. Resting EEG spectral slopes are associated with age-related differences in information processing speed. Biol Psychol. 2022;168:108261. https:\/\/doi.org\/10.1016\/j.biopsycho.2022.108261.","journal-title":"Biol Psychol"},{"key":"2077_CR40","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/s11357-023-00836-z","volume":"46","author":"A Czoch","year":"2024","unstructured":"Czoch A, Kaposzta Z, Mukli P, et al. Resting-state fractal brain connectivity is associated with impaired cognitive performance in healthy aging. Geroscience. 2024;46:473\u201389. https:\/\/doi.org\/10.1007\/s11357-023-00836-z.","journal-title":"Geroscience"},{"key":"2077_CR41","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.3389\/fphys.2018.01072","volume":"9","author":"P Mukli","year":"2018","unstructured":"Mukli P, Nagy Z, Racz FS, et al. Impact of healthy aging on multifractal hemodynamic fluctuations in the human prefrontal cortex. Front Physiol. 2018;9:1072. https:\/\/doi.org\/10.3389\/fphys.2018.01072.","journal-title":"Front Physiol"},{"key":"2077_CR42","unstructured":"Racz FS, Milton J, Cabrera JL, et al. Multi-modal spectral parametrization method (MMSPM) for analyzing EEG activity with distinct scaling regimes n.d. https:\/\/arxiv.org\/html\/2505.18117v1. Accessed 28 Oct 2025."},{"key":"2077_CR43","doi-asserted-by":"publisher","first-page":"13257","DOI":"10.1523\/JNEUROSCI.2332-14.2015","volume":"35","author":"B Voytek","year":"2015","unstructured":"Voytek B, Kramer MA, Case J, et al. Age-related changes in 1\/f neural electrophysiological noise. J Neurosci. 2015;35:13257\u201365. https:\/\/doi.org\/10.1523\/JNEUROSCI.2332-14.2015.","journal-title":"J Neurosci"}],"container-title":["GeroScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-025-02077-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11357-025-02077-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11357-025-02077-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:29:46Z","timestamp":1791188986000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11357-025-02077-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,16]]},"references-count":43,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2077"],"URL":"https:\/\/doi.org\/10.1007\/s11357-025-02077-8","relation":{},"ISSN":["2509-2723"],"issn-type":[{"value":"2509-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,16]]},"assertion":[{"value":"22 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}