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Animal work with naked mole rats was approved by the University of Illinois Chicago Institutional Animal Care and Use Committee. The university\u2019s Animal Welfare Assurance Number D16-00290 (A3460-01) is on file with the Office of Laboratory Animal Welfare (OLAW), National Institutes of Health. The work is reported in compliance with the Animal Research: Reporting in Vivo Experiments (ARRIVE) guidelines, version 2.0 [\n                      \n                      ]. In total, 8 NMR (four young and four middle-aged) and 9 mouse (five young and four middle-aged) were used in this study. All experiments involving live animals were conducted in strict accordance with the national and regional ethical guidelines, and animals were treated by Federation of Laboratory Animal Science Association (FELASA) certified personnel.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No human subjects were involved in this study.","order":2,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}