{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:49:10Z","timestamp":1789588150111,"version":"build-2803163510"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T00:00:00Z","timestamp":1486512000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Nat Med"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1007\/s11418-017-1075-8","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T11:58:58Z","timestamp":1486555138000},"page":"482-491","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Anti-obesity activity of Yamabushitake (Hericium erinaceus) powder in ovariectomized mice, and its potentially active compounds"],"prefix":"10.1007","volume":"71","author":[{"given":"Eri","family":"Hiraki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Furuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rika","family":"Kuwahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomichi","family":"Takemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiki","family":"Akasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bungo","family":"Shirouchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Ohnuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-6060","authenticated-orcid":false,"given":"Kuniyoshi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,8]]},"reference":[{"key":"1075_CR1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.archger.2005.08.005","volume":"42","author":"J Miquel","year":"2006","unstructured":"Miquel J, Ramirez-Bosca A, Ramirez-Bosca JV, Alperi JD (2006) Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidants. Arch Gerontol Geriatr 42:289\u2013306","journal-title":"Arch Gerontol Geriatr"},{"key":"1075_CR2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0531-5565(94)90012-4","volume":"29","author":"F Kronenberg","year":"1994","unstructured":"Kronenberg F (1994) Hot flashes: phenomenology, quality of life, and search for treatment options. Exp Gerontol 29:319\u2013336","journal-title":"Exp Gerontol"},{"key":"1075_CR3","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/S0378-5122(01)00204-3","volume":"38","author":"AR Genazzani","year":"2001","unstructured":"Genazzani AR, Gambacciani M (2001) HRT in the third millennium. Maturitas 38:S49\u2013S55","journal-title":"Maturitas"},{"key":"1075_CR4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/pds.1273","volume":"16","author":"MP Guay","year":"2007","unstructured":"Guay MP, Dragomir A, Pilon D, Moride Y, Perreault S (2007) Changes in pattern of use, clinical characteristics and persistence rate of hormone replacement therapy among postmenopausal women after the WHI publication. Pharmacoepidemiol Drug Saf 16:17\u201327","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"1075_CR5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","volume":"288","author":"JE Rossouw","year":"2002","unstructured":"Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women\u2019s Health Initiative randomized controlled trial. JAMA 288:321\u2013333","journal-title":"JAMA"},{"key":"1075_CR6","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.cmet.2006.10.002","volume":"4","author":"JG Schneider","year":"2006","unstructured":"Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF (2006) ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metab 4:377\u2013389","journal-title":"Cell Metab"},{"key":"1075_CR7","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1586\/14779072.4.6.871","volume":"4","author":"H Bays","year":"2006","unstructured":"Bays H, Blonde L, Rosenson R (2006) Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients? Expert Rev Cardiovasc Ther 4:871\u2013895","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"1075_CR8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1051\/jbio:2006011","volume":"200","author":"A Mazzucotelli","year":"2006","unstructured":"Mazzucotelli A, Langin D (2006) Fatty acid mobilization and their use in adipose tissue. J Soc Biol 200:83\u201391","journal-title":"J Soc Biol"},{"key":"1075_CR9","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1001\/archpedi.160.9.894","volume":"160","author":"AF Reeves","year":"2006","unstructured":"Reeves AF, Rees JM, Schiff M, Hujoel P (2006) Total body weight and waist circumference associated with chronic periodontitis among adolescents in the United States. Arch Pediatr Adolesc Med 160:894\u2013899","journal-title":"Arch Pediatr Adolesc Med"},{"key":"1075_CR10","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/ijc.20529","volume":"113","author":"S Kuriyama","year":"2005","unstructured":"Kuriyama S, Tsubono Y, Hozawa A, Shimazu T, Suzuki Y, Koizumi Y, Suzuki Y, Ohmori K, Nishino Y, Tsuji I (2005) Obesity and risk of cancer in Japan. Int J Cancer 113:148\u2013157","journal-title":"Int J Cancer"},{"key":"1075_CR11","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.canlet.2010.05.006","volume":"297","author":"JS Lee","year":"2010","unstructured":"Lee JS, Hong EK (2010) Hericium erinaceus enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells. Cancer Lett 297:144\u2013154","journal-title":"Cancer Lett"},{"key":"1075_CR12","first-page":"461","volume":"17","author":"JC Wang","year":"2001","unstructured":"Wang JC, Hu SH, Su CH, Lee TM (2001) Antitumor and immunoenhancing activities of polysaccharide from culture broth of Hericium spp. Kaohsiung J Med Sci 17:461\u2013467","journal-title":"Kaohsiung J Med Sci"},{"key":"1075_CR13","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/0031-9422(91)80050-B","volume":"34","author":"K Okamoto","year":"1993","unstructured":"Okamoto K, Shimada A, Shirai R, Sakamoto H, Yoshida S, Ojima F, Ishiguro Y, Sakai T, Kawagishi H (1993) Antimicrobial chlorinated orcinol derivatives from mycelia of Hericium erinaceum. Phytochemistry 34:1445\u20131446","journal-title":"Phytochemistry"},{"key":"1075_CR14","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0963-9969(01)00150-8","volume":"35","author":"JL Mau","year":"2002","unstructured":"Mau JL, Lin HC, Song SF (2002) Antioxidant properties of several specialty mushrooms. Food Res Int 35:519\u2013526","journal-title":"Food Res Int"},{"key":"1075_CR15","first-page":"71615","volume":"2010","author":"YR Li","year":"2010","unstructured":"Li YR, Zhang GQ, Ng TB, Wang HX (2010) A novel lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from dried fruiting bodies of the monkey head mushroom Hericium erinaceum. J Biomed Biotechnol 2010:71615","journal-title":"J Biomed Biotechnol"},{"key":"1075_CR16","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1248\/bpb.31.1727","volume":"31","author":"K Mori","year":"2008","unstructured":"Mori K, Obara Y, Hirota M, Azumi Y, Kinugasa S, Inatomi S, Nakahata N (2008) Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biol Pharm Bull 31:1727\u20131732","journal-title":"Biol Pharm Bull"},{"key":"1075_CR17","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/ptr.2634","volume":"23","author":"K Mori","year":"2009","unstructured":"Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T (2009) Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res 23:367\u2013372","journal-title":"Phytother Res"},{"key":"1075_CR18","doi-asserted-by":"crossref","first-page":"231","DOI":"10.2220\/biomedres.31.231","volume":"31","author":"M Nagano","year":"2010","unstructured":"Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K (2010) Reduction of depression and anxiety by 4\u00a0weeks Hericium erinaceus intake. Biomed Res 31:231\u2013237","journal-title":"Biomed Res"},{"key":"1075_CR19","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1271\/bbb.100130","volume":"74","author":"K Hiwatashi","year":"2010","unstructured":"Hiwatashi K, Kosaka Y, Suzuki N, Hata K, Mukaiyama T, Sakamoto K, Shirakawa H, Komai M (2010) Yamabushitake mushroom (Hericium erinaceus) improved lipid metabolism in mice fed a high-fat diet. Biosci Biotechnol Biochem 74:1447\u20131451","journal-title":"Biosci Biotechnol Biochem"},{"key":"1075_CR20","unstructured":"Ministry of Health, Labour and Welfare (2008) Annual Health, Labour and Welfare Report 2007\u20132008. http:\/\/www.mhlw.go.jp\/english\/wp\/wp-hw2\/index.html . Accessed 22 Dec 2014"},{"key":"1075_CR21","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","volume":"226","author":"J Folch","year":"1957","unstructured":"Folch J, Lees M, Stanley GHS (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226:497\u2013509","journal-title":"J Biol Chem"},{"key":"1075_CR22","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3177\/jnsv.56.48","volume":"56","author":"T Mizutani","year":"2010","unstructured":"Mizutani T, Inatomi S, Inazu A, Kawahara E (2010) Hypolipidemic effect of Pleurotus eryngii extract in fat-loaded mice. J Nutr Sci Vitaminol 56:48\u201353","journal-title":"J Nutr Sci Vitaminol"},{"key":"1075_CR23","doi-asserted-by":"crossref","first-page":"4561","DOI":"10.1016\/0040-4039(91)80039-9","volume":"32","author":"H Kawagishi","year":"1991","unstructured":"Kawagishi H, Ando M, Sakamoto H, Yoshida S, Ojima F, Ishiguro Y, Ukai N, Furukawa S (1991) Hericenones C, D and E, stimulators of nerve growth factor (NGF)-synthesis, from the mushroom Hericium erinaceum. Tetrahedron Lett 32:4561\u20134564","journal-title":"Tetrahedron Lett"},{"key":"1075_CR24","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0031-9422(92)80127-Z","volume":"32","author":"H Kawagishi","year":"1993","unstructured":"Kawagishi H, Ando M, Shinba K, Sakamoto H, Yoshida S, Ojima F, Ishiguro Y, Ukai N, Furukawa S (1993) Chromans, hericenones F, G and H from the mushroom Hericium erinaceum. Phytochemistry 32:175\u2013178","journal-title":"Phytochemistry"},{"key":"1075_CR25","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.2337\/diab.45.10.1435","volume":"45","author":"M Wabitsch","year":"1996","unstructured":"Wabitsch M, Jensen PB, Blum WF, Christoffersen CT, Englaro P, Heinze E, Rascher W, Teller W, Tornqvist H, Hauner H (1996) Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes 45:1435\u20131438","journal-title":"Diabetes"},{"key":"1075_CR26","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.nut.2011.07.014","volume":"28","author":"A Ludgero-Correia Jr","year":"2012","unstructured":"Ludgero-Correia A Jr, Aguila MB, Mandarim-de-Lacerda CA, Faria TS (2012) Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL\/6 mice. Nutrition 28:316\u2013323","journal-title":"Nutrition"},{"key":"1075_CR27","doi-asserted-by":"crossref","first-page":"9960","DOI":"10.1073\/pnas.0501632102","volume":"102","author":"HB Wang","year":"2005","unstructured":"Wang HB, Tranguch S, Xie HR, Hanley G, Das SK, Dey SK (2005) Variation in commercial rodent diets induces disparate molecular and physiological changes in the mouse uterus. Proc Natl Acad Sci USA 102:9960\u20139965","journal-title":"Proc Natl Acad Sci USA"},{"key":"1075_CR28","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0021-9150(00)00456-1","volume":"151","author":"E Ros","year":"2000","unstructured":"Ros E (2000) Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk. Atherosclerosis 151:357\u2013379","journal-title":"Atherosclerosis"},{"key":"1075_CR29","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0140-6736(97)11509-4","volume":"352","author":"L Sjostrom","year":"1998","unstructured":"Sjostrom L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HP, Krempf M (1998) Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Lancet 352:167\u2013172","journal-title":"Lancet"},{"key":"1075_CR30","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/ijo.2009.252","volume":"34","author":"G Gariepy","year":"2010","unstructured":"Gariepy G, Nitka D, Schmitz N (2010) The association between obesity and anxiety disorders in the population: a systematic review and meta-analysis. Int J Obes 34:407\u2013419","journal-title":"Int J Obes"},{"key":"1075_CR31","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2010.2","volume":"67","author":"FS Luppino","year":"2010","unstructured":"Luppino FS, de Wit LM, Bouvy PF, Stijnen T, Cuijpers P, Penninx BW, Zitman FG (2010) Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 67:220\u2013229","journal-title":"Arch Gen Psychiatry"}],"container-title":["Journal of Natural Medicines"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11418-017-1075-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11418-017-1075-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11418-017-1075-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T20:31:23Z","timestamp":1658608283000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11418-017-1075-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,8]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["1075"],"URL":"https:\/\/doi.org\/10.1007\/s11418-017-1075-8","relation":{},"ISSN":["1340-3443","1861-0293"],"issn-type":[{"value":"1340-3443","type":"print"},{"value":"1861-0293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,8]]}}}