{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:52:16Z","timestamp":1786981936401,"version":"build-2736575974"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci. China Life Sci."],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s11427-020-1924-4","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T15:33:05Z","timestamp":1620142385000},"page":"206-214","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Genomic polymorphisms at the crhr2 locus improve feed conversion efficiency through alleviation of hypothalamus-pituitary-interrenal axis activity in gibel carp (Carassius gibelio)"],"prefix":"10.1007","volume":"65","author":[{"given":"Chuang","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyong","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beide","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junyan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangyan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouqi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingou","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfang","family":"Gui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"1924_CR1","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1093\/oxfordjournals.jhered.a109263","volume":"70","author":"DK Belyaev","year":"1979","unstructured":"Belyaev, D.K. (1979). Destabilizing selection as a factor in domestication. J Hered 70, 301\u2013308.","journal-title":"J Hered"},{"key":"1924_CR2","doi-asserted-by":"publisher","first-page":"E983","DOI":"10.1152\/ajpendo.00234.2014","volume":"307","author":"FA Britto","year":"2014","unstructured":"Britto, F.A., Begue, G., Rossano, B., Docquier, A., Vernus, B., Sar, C., Ferry, A., Bonnieu, A., Ollendorff, V., and Favier, F.B. (2014). REDD1 deletion prevents dexamethasone-induced skeletal muscle atrophy. Am J Physiol Endocrinol Metab 307, E983\u2013E993.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"1924_CR3","doi-asserted-by":"publisher","first-page":"7380","DOI":"10.1073\/pnas.1801024115","volume":"115","author":"I Brusini","year":"2018","unstructured":"Brusini, I., Carneiro, M., Wang, C., Rubin, C.J., Ring, H., Afonso, S., Blanco-Aguiar, J.A., Ferrand, N., Rafati, N., Villafuerte, R., et al. (2018). Changes in brain architecture are consistent with altered fear processing in domestic rabbits. Proc Natl Acad Sci USA 115, 7380\u20137385.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1924_CR4","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1126\/science.1260149","volume":"347","author":"L Cao","year":"2015","unstructured":"Cao, L., Naylor, R., Henriksson, P., Leadbitter, D., Metian, M., Troell, M., and Zhang, W. (2015). China\u2019s aquaculture and the world\u2019s wild fisheries. Science 347, 133\u2013135.","journal-title":"Science"},{"key":"1924_CR5","doi-asserted-by":"publisher","first-page":"3124","DOI":"10.1111\/mec.12354","volume":"22","author":"J Catchen","year":"2013","unstructured":"Catchen, J., Hohenlohe, P.A., Bassham, S., Amores, A., and Cresko, W.A. (2013). Stacks: an analysis tool set for population genomics. Mol Ecol 22, 3124\u20133140.","journal-title":"Mol Ecol"},{"key":"1924_CR6","doi-asserted-by":"publisher","first-page":"T77","DOI":"10.1530\/JME-15-0323","volume":"56","author":"NX Cawley","year":"2016","unstructured":"Cawley, N.X., Li, Z., and Loh, Y.P. (2016). 60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides. J Mol Endocrinol 56, T77\u2013T97.","journal-title":"J Mol Endocrinol"},{"key":"1924_CR7","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1111\/raq.12202","volume":"10","author":"H de Verdal","year":"2018","unstructured":"de Verdal, H., Komen, H., Quillet, E., Chatain, B., Allal, F., Benzie, J.A.H., and Vandeputte, M. (2018). Improving feed efficiency in fish using selective breeding: a review. Rev Aquacult 10, 833\u2013851.","journal-title":"Rev Aquacult"},{"key":"1924_CR8","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/j.1095-8649.1985.tb03208.x","volume":"27","author":"G Degani","year":"1985","unstructured":"Degani, G., and Lee-Gallagher, M. (1985). The relationship between growth, food conversion and oxygen consumption in developed and underdeveloped American eels, Anguilla rostrata Lesueur. J Fish Biol 27, 635\u2013641.","journal-title":"J Fish Biol"},{"key":"1924_CR9","doi-asserted-by":"publisher","first-page":"9971","DOI":"10.1073\/pnas.0901586106","volume":"106","author":"CA Driscoll","year":"2009","unstructured":"Driscoll, C.A., Macdonald, D.W., and O\u2019Brien, S.J. (2009). From wild animals to domestic pets, an evolutionary view of domestication. Proc Natl Acad Sci USA 106, 9971\u20139978.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1924_CR10","doi-asserted-by":"publisher","first-page":"E1093","DOI":"10.1152\/ajpendo.00045.2019","volume":"316","author":"E Faught","year":"2019","unstructured":"Faught, E., and Vijayan, M.M. (2019). Loss of the glucocorticoid receptor in zebrafish improves muscle glucose availability and increases growth. Am J Physiol Endocrinol Metab 316, E1093\u2013E1104.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"1924_CR11","doi-asserted-by":"publisher","first-page":"28679","DOI":"10.1038\/srep28679","volume":"6","author":"B Fu","year":"2016","unstructured":"Fu, B., Liu, H., Yu, X., and Tong, J. (2016). A high-density genetic map and growth related QTL mapping in bighead carp (Hypophthalmichthys nobilis). Sci Rep 6, 28679.","journal-title":"Sci Rep"},{"key":"1924_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1139\/d98-024","volume":"55","author":"MR Gross","year":"1998","unstructured":"Gross, M.R. (1998). One species with two biologies: Atlantic salmon (Salmo salar) in the wild and in aquaculture. Can J Fish Aquat Sci 55, 131\u2013144.","journal-title":"Can J Fish Aquat Sci"},{"key":"1924_CR13","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s11427-010-0092-6","volume":"53","author":"JF Gui","year":"2010","unstructured":"Gui, J.F., and Zhou, L. (2010). Genetic basis and breeding application of clonal diversity and dual reproduction modes in polyploid Carassius auratus gibelio. Sci China Life Sci 53, 409\u2013415.","journal-title":"Sci China Life Sci"},{"key":"1924_CR14","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1093\/jmcb\/mjy036","volume":"11","author":"G Heras","year":"2018","unstructured":"Heras, G., Namuduri, A.V., Traini, L., Shevchenko, G., Falk, A., Bergstr\u00f6m Lind, S., Jia, M., Tian, G., and Gastaldello, S. (2018). Muscle RING-finger protein-1 (MuRF1) functions and cellular localization are regulated by SUMO1 post-translational modification. J Mol Cell Biol 11, 356\u2013370.","journal-title":"J Mol Cell Biol"},{"key":"1924_CR15","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0091-679X(10)97022-2","volume":"97","author":"KM Jaffe","year":"2010","unstructured":"Jaffe, K.M., Thiberge, S.Y., Bisher, M.E., and Burdine, R.D. (2010). Imaging cilia in zebrafish. Methods Cell Biol 97, 415\u2013435.","journal-title":"Methods Cell Biol"},{"key":"1924_CR16","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1146\/annurev-animal-022513-114135","volume":"2","author":"P Jensen","year":"2014","unstructured":"Jensen, P. (2014). Behavior genetics and the domestication of animals. Annu Rev Anim Biosci 2, 85\u2013104.","journal-title":"Annu Rev Anim Biosci"},{"key":"1924_CR17","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1146\/annurev-animal-030117-014838","volume":"7","author":"SW Kim","year":"2019","unstructured":"Kim, S.W., Less, J.F., Wang, L., Yan, T., Kiron, V., Kaushik, S.J., and Lei, X.G. (2019). Meeting global feed protein demand: challenge, opportunity, and strategy. Annu Rev Anim Biosci 7, 221\u2013243.","journal-title":"Annu Rev Anim Biosci"},{"key":"1924_CR18","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/0044-8486(83)90276-4","volume":"32","author":"B Kinghorn","year":"1983","unstructured":"Kinghorn, B. (1983). Genetic variation in food conversion efficiency and growth in rainbow trout. Aquaculture 32, 141\u2013155.","journal-title":"Aquaculture"},{"key":"1924_CR19","doi-asserted-by":"publisher","first-page":"2199","DOI":"10.1210\/en.2013-1938","volume":"155","author":"D Li","year":"2014","unstructured":"Li, D., Lou, Q., Zhai, G., Peng, X., Cheng, X., Dai, X., Zhuo, Z., Shang, G., Jin, X., Chen, X., et al. (2014). Hyperplasia and cellularity changes in IGF-1-overexpressing skeletal muscle of crucian carp. Endocrinology 155, 2199\u20132212.","journal-title":"Endocrinology"},{"key":"1924_CR20","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1186\/s12864-019-5777-z","volume":"20","author":"WJ Lu","year":"2019","unstructured":"Lu, W.J., Gao, F.X., Wang, Y., Zhang, Q.Y., Li, Z., Zhang, X.J., Zhou, L., and Gui, J.F. (2019). Differential expression of innate and adaptive immune genes in the survivors of three gibel carp gynogenetic clones after herpesvirus challenge. BMC Genomics 20, 432.","journal-title":"BMC Genomics"},{"key":"1924_CR21","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1023\/A:1008924418720","volume":"9","author":"TP Mommsen","year":"1999","unstructured":"Mommsen, T.P., Vijayan, M.M., and Moon, T.W. (1999). Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation. Rev Fish Biol Fish 9, 211\u2013268.","journal-title":"Rev Fish Biol Fish"},{"key":"1924_CR22","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1038\/35016500","volume":"405","author":"RL Naylor","year":"2000","unstructured":"Naylor, R.L., Goldburg, R.J., Primavera, J.H., Kautsky, N., Beveridge, M. C.M., Clay, J., Folke, C., Lubchenco, J., Mooney, H., and Troell, M. (2000). Effect of aquaculture on world fish supplies. Nature 405, 1017\u20131024.","journal-title":"Nature"},{"key":"1924_CR23","doi-asserted-by":"publisher","first-page":"170087","DOI":"10.1016\/j.peptides.2019.04.014","volume":"120","author":"JSW On","year":"2019","unstructured":"On, J.S.W., Arokiaraj, A.W.R., and Chow, B.K.C. (2019). Molecular evolution of CRH and CRHR subfamily before the evolutionary origin of vertebrate. Peptides 120, 170087.","journal-title":"Peptides"},{"key":"1924_CR24","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/j.1749-6632.1999.tb08687.x","volume":"885","author":"MH Perrin","year":"1999","unstructured":"Perrin, M.H., and Vale, W.W. (1999). Corticotropin releasing factor receptors and their ligand family. Ann New York Acad Sci 885, 312\u2013328.","journal-title":"Ann New York Acad Sci"},{"key":"1924_CR25","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1038\/305325a0","volume":"305","author":"C Rivier","year":"1983","unstructured":"Rivier, C., and Vale, W. (1983). Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin. Nature 305, 325\u2013327.","journal-title":"Nature"},{"key":"1924_CR26","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.mce.2017.02.031","volume":"447","author":"ML Rossetti","year":"2017","unstructured":"Rossetti, M.L., Steiner, J.L., and Gordon, B.S. (2017). Androgen-mediated regulation of skeletal muscle protein balance. Mol Cell Endocrinol 447, 35\u201344.","journal-title":"Mol Cell Endocrinol"},{"key":"1924_CR27","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1016\/j.cell.2017.02.004","volume":"168","author":"RA Saxton","year":"2017","unstructured":"Saxton, R.A., and Sabatini, D.M. (2017). mTOR signaling in growth, metabolism, and disease. Cell 168, 960\u2013976.","journal-title":"Cell"},{"key":"1924_CR28","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1093\/jmcb\/mjz053","volume":"12","author":"C Shi","year":"2020","unstructured":"Shi, C., Lu, Y., Zhai, G., Huang, J., Shang, G., Lou, Q., Li, D., Jin, X., He, J., Du, Z., et al. (2020). Hyperandrogenism in POMCa-deficient zebrafish enhances somatic growth without increasing adiposity. J Mol Cell Biol 12, 291\u2013304.","journal-title":"J Mol Cell Biol"},{"key":"1924_CR29","doi-asserted-by":"publisher","first-page":"383","DOI":"10.31887\/DCNS.2006.8.4\/ssmith","volume":"8","author":"SM Smith","year":"2006","unstructured":"Smith, S.M., and Vale, W.W. (2006). The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin Neurosci 8, 383\u2013395.","journal-title":"Dialogues Clin Neurosci"},{"key":"1924_CR30","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/0044-8486(82)90008-4","volume":"28","author":"JL Specker","year":"1982","unstructured":"Specker, J.L. (1982). Interrenal function and smoltification. Aquaculture 28, 59\u201366.","journal-title":"Aquaculture"},{"key":"1924_CR31","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/faf.12006","volume":"15","author":"F Teletchea","year":"2014","unstructured":"Teletchea, F., and Fontaine, P. (2014). Levels of domestication in fish: implications for the sustainable future of aquaculture. Fish Fish 15, 181\u2013195.","journal-title":"Fish Fish"},{"key":"1924_CR32","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/bies.200800070","volume":"31","author":"L Trut","year":"2010","unstructured":"Trut, L., Oskina, I., and Kharlamova, A. (2010). Animal evolution during domestication: the domesticated fox as a model. Bioessays 31, 349\u2013360.","journal-title":"Bioessays"},{"key":"1924_CR33","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1210\/edrv-15-4-409","volume":"15","author":"NC Vamvakopoulos","year":"1994","unstructured":"Vamvakopoulos, N.C., and Chrousos, G.P. (1994). Hormonal regulation of human corticotropin-releasing hormone gene expression: implications for the stress response and immune\/inflammatory reaction. Endocr Rev 15, 409\u2013420.","journal-title":"Endocr Rev"},{"key":"1924_CR34","doi-asserted-by":"publisher","first-page":"160030","DOI":"10.1098\/rsos.160030","volume":"3","author":"MA Vindas","year":"2016","unstructured":"Vindas, M.A., Johansen, I.B., Folkedal, O., H\u00f6glund, E., Gorissen, M., Flik, G., Kristiansen, T.S., and \u00d8verli, \u00d8. (2016). Brain serotonergic activation in growth-stunted farmed salmon: adaption versus pathology. R Soc Open sci 3, 160030.","journal-title":"R Soc Open sci"},{"key":"1924_CR35","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1523\/JNEUROSCI.3339-10.2011","volume":"31","author":"M Wagle","year":"2011","unstructured":"Wagle, M., Mathur, P., and Guo, S. (2011). Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol. J Neurosci 31, 214\u2013224.","journal-title":"J Neurosci"},{"key":"1924_CR36","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1038\/nmeth.2023","volume":"9","author":"S Wang","year":"2012","unstructured":"Wang, S., Meyer, E., McKay, J.K., and Matz, M.V. (2012). 2b-RAD: a simple and flexible method for genome-wide genotyping. Nat Methods 9, 808\u2013810.","journal-title":"Nat Methods"},{"key":"1924_CR37","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1007\/s11427-018-9371-4","volume":"62","author":"S Wen","year":"2019","unstructured":"Wen, S., Wang, C., Gong, M., and Zhou, L. (2019). An overview of energy and metabolic regulation. Sci China Life Sci 62, 771\u2013790.","journal-title":"Sci China Life Sci"},{"key":"1924_CR38","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1111\/anu.12855","volume":"25","author":"WJ Xu","year":"2019","unstructured":"Xu, W.J., Jin, J.Y., Zou, T., Han, D., Liu, H.K., Zhu, X.M., Yang, Y.X., and Xie, S.Q. (2019). Growth, feed utilization and metabolic responses of three gibel carp (Carassius gibelio) strains to fishmeal and plant protein-based diets. Aquacult Nutr 25, 319\u2013332.","journal-title":"Aquacult Nutr"},{"key":"1924_CR39","doi-asserted-by":"publisher","first-page":"3549","DOI":"10.1210\/en.2018-00551","volume":"159","author":"G Zhai","year":"2018","unstructured":"Zhai, G., Shu, T., Xia, Y., Lu, Y., Shang, G., Jin, X., He, J., Nie, P., and Yin, Z. (2018). Characterization of sexual trait development in cyp17a1-deficient zebrafish. Endocrinology 159, 3549\u20133562.","journal-title":"Endocrinology"},{"key":"1924_CR40","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s11427-018-9489-x","volume":"62","author":"Y Zhang","year":"2019","unstructured":"Zhang, Y., Ren, H., Wang, Q., Deng, W., Yue, W., Yan, H., Tan, L., Chen, Q., Yang, G., Lu, T., et al. (2019). Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance. Sci China Life Sci 62, 535\u2013543.","journal-title":"Sci China Life Sci"},{"key":"1924_CR41","first-page":"103","volume":"2","author":"L Zhou","year":"2017","unstructured":"Zhou, L., and Gui, J. (2017). Natural and artificial polyploids in aquaculture. Aquacult Fish 2, 103\u2013111.","journal-title":"Aquacult Fish"},{"key":"1924_CR42","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1038\/mp.2012.64","volume":"18","author":"L Ziv","year":"2013","unstructured":"Ziv, L., Muto, A., Schoonheim, P.J., Meijsing, S.H., Strasser, D., Ingraham, H.A., Schaaf, M.J.M., Yamamoto, K.R., and Baier, H. (2013). An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Mol Psychiatry 18, 681\u2013691.","journal-title":"Mol Psychiatry"}],"container-title":["Science China Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-020-1924-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11427-020-1924-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-020-1924-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T08:38:00Z","timestamp":1675240680000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11427-020-1924-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["1924"],"URL":"https:\/\/doi.org\/10.1007\/s11427-020-1924-4","relation":{},"ISSN":["1674-7305","1869-1889"],"issn-type":[{"value":"1674-7305","type":"print"},{"value":"1869-1889","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,30]]},"assertion":[{"value":"14 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}