{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:05:16Z","timestamp":1792623916216,"version":"4.5.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci. China Life Sci."],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s11427-022-2391-x","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T05:01:35Z","timestamp":1697086895000},"page":"379-390","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effects of weaning on intestinal longitudinal muscle-myenteric plexus function in piglets"],"prefix":"10.1007","volume":"67","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fenfen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaibin","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengjia","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"2391_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/2075614","volume":"2019","author":"P Aiello","year":"2019","unstructured":"Aiello, P., Sharghi, M., Mansourkhani, S.M., Ardekan, A.P., Jouybari, L., Daraei, N., Peiro, K., Mohamadian, S., Rezaei, M., Heidari, M., et al. (2019). Medicinal plants in the prevention and treatment of colon cancer. Oxid Med Cell Longev 2019, 1\u201351.","journal-title":"Oxid Med Cell Longev"},{"key":"2391_CR2","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.ijdevneu.2011.06.010","volume":"29","author":"RS Balk","year":"2011","unstructured":"Balk, R.S., Silva, M.H., Bridi, J.C., Carvalho, N.R., Portella, R.L., Dobrachinski, F., Amaral, G.P., Barcelos, R., Dias, G.R.M., Rocha, J.B.T., et al. (2011). Effect of repeated restraint stress and clomipramine on Na+\/K+-ATPase activity and behavior in rats. Int J Dev Neurosci 29, 909\u2013916.","journal-title":"Int J Dev Neurosci"},{"key":"2391_CR3","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3389\/fcimb.2018.00074","volume":"8","author":"P Brun","year":"2018","unstructured":"Brun, P., Qesari, M., Marconi, P.C., Kotsafti, A., Porzionato, A., Macchi, V., Schwendener, R.A., Scarpa, M., Giron, M.C., Pal\u00f9, G., et al. (2018). Herpes simplex virus type 1 infects enteric neurons and triggers gut dysfunction via macrophage recruitment. Front Cell Infect Microbiol 8, 74.","journal-title":"Front Cell Infect Microbiol"},{"key":"2391_CR4","doi-asserted-by":"publisher","first-page":"6443","DOI":"10.1172\/JCI126584","volume":"130","author":"X Chen","year":"2020","unstructured":"Chen, X., Meng, X., Zhang, H., Feng, C., Wang, B., Li, N., Abdullahi, K.M., Wu, X., Yang, J., Li, Z., et al. (2020). Intestinal proinflammatory macrophages induce a phenotypic switch in interstitial cells of Cajal. J Clin Invest 130, 6443\u20136456.","journal-title":"J Clin Invest"},{"key":"2391_CR5","doi-asserted-by":"publisher","first-page":"571","DOI":"10.3233\/JPD-140422","volume":"4","author":"AG Corbill\u00e9","year":"2014","unstructured":"Corbill\u00e9, A.G., Coron, E., Neunlist, M., Derkinderen, P., and Lebouvier, T. (2014). Appraisal of the dopaminergic and noradrenergic innervation of the submucosal plexus in PD. J Parkinsons Dis 4, 571\u2013576.","journal-title":"J Parkinsons Dis"},{"key":"2391_CR6","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.phymed.2016.03.007","volume":"23","author":"K Cortese","year":"2016","unstructured":"Cortese, K., Daga, A., Monticone, M., Tavella, S., Stefanelli, A., Aiello, C., Bisio, A., Bellese, G., and Castagnola, P. (2016). Carnosic acid induces proteasomal degradation of Cyclin B1, RB and SOX2 along with cell growth arrest and apoptosis in GBM cells. Phytomedicine 23, 679\u2013685.","journal-title":"Phytomedicine"},{"key":"2391_CR7","doi-asserted-by":"publisher","first-page":"161","DOI":"10.5056\/jnm.2013.19.2.161","volume":"19","author":"I Demedts","year":"2013","unstructured":"Demedts, I., Masaoka, T., Kindt, S., Hertogh, G.D., Geboes, K., Farr\u00e9, R., Berghe, P.V., and Tack, J. (2013). Gastrointestinal motility changes and myenteric plexus alterations in spontaneously diabetic biobreeding rats. J Neurogastroenterol Motil 19, 161\u2013170.","journal-title":"J Neurogastroenterol Motil"},{"key":"2391_CR8","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1080\/15384101.2018.1553336","volume":"17","author":"R Drissi","year":"2018","unstructured":"Drissi, R., Chauvin, A., McKenna, A., L\u00e9vesque, D., Blais-Brochu, S., Jean, D., and Boisvert, F.M. (2018). Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks. Cell Cycle 17, 2593\u20132609.","journal-title":"Cell Cycle"},{"key":"2391_CR9","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.dld.2011.07.007","volume":"43","author":"R Farra","year":"2011","unstructured":"Farra, R., Dapas, B., Pozzato, G., Scaggiante, B., Agostini, F., Zennaro, C., Grassi, M., Rosso, N., Giansante, C., Fiotti, N., et al. (2011). Effects of E2F1-cyclin E1-E2 circuit down regulation in hepatocellular carcinoma cells. Dig Liver Dis 43, 1006\u20131014.","journal-title":"Dig Liver Dis"},{"key":"2391_CR10","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/BF00341410","volume":"171","author":"MS Faussone-Pellegrini","year":"1985","unstructured":"Faussone-Pellegrini, M.S. (1985). Cytodifferentiation of the interstitial cells of Cajal related to the myenteric plexus of mouse intestinal muscle coat. Anat Embryol 171, 163\u2013169.","journal-title":"Anat Embryol"},{"key":"2391_CR11","doi-asserted-by":"publisher","first-page":"3883","DOI":"10.1038\/s41467-021-24199-1","volume":"12","author":"X Feng","year":"2021","unstructured":"Feng, X., Noguchi, Y., Barbon, M., Stillman, B., Speck, C., and Li, H. (2021). The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6. Nat Commun 12, 3883.","journal-title":"Nat Commun"},{"key":"2391_CR12","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1111\/evj.13160","volume":"52","author":"C Fintl","year":"2020","unstructured":"Fintl, C., Lindberg, R., and McL. Press, C. (2020). Myenteric networks of interstitial cells of Cajal are reduced in horses with inflammatory bowel disease. Equine Vet J 52, 298\u2013304.","journal-title":"Equine Vet J"},{"key":"2391_CR13","doi-asserted-by":"publisher","first-page":"4540","DOI":"10.3390\/ijms21124540","volume":"21","author":"D Foong","year":"2020","unstructured":"Foong, D., Zhou, J., Zarrouk, A., Ho, V., and O\u2019Connor, M.D. (2020). Understanding the biology of human interstitial cells of Cajal in gastrointestinal motility. Int J Mol Sci 21, 4540.","journal-title":"Int J Mol Sci"},{"key":"2391_CR14","doi-asserted-by":"publisher","first-page":"4505","DOI":"10.1007\/s00018-020-03543-6","volume":"77","author":"C Fung","year":"2020","unstructured":"Fung, C., and Vanden Berghe, P. (2020). Functional circuits and signal processing in the enteric nervous system. Cell Mol Life Sci 77, 4505\u20134522.","journal-title":"Cell Mol Life Sci"},{"key":"2391_CR15","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1007\/s11427-022-2246-4","volume":"66","author":"J Gao","year":"2023","unstructured":"Gao, J., Yang, Z., Zhao, C., Tang, X., Jiang, Q., and Yin, Y. (2023). A comprehensive review on natural phenolic compounds as alternatives to in-feed antibiotics. Sci China Life Sci 66, 1518\u20131534.","journal-title":"Sci China Life Sci"},{"key":"2391_CR16","doi-asserted-by":"publisher","first-page":"114479","DOI":"10.1016\/j.bcp.2021.114479","volume":"186","author":"Y Gao","year":"2021","unstructured":"Gao, Y., Tang, Y., Zhang, H., Chu, X., Yan, B., Li, J., and Liu, C. (2021). Vincristine leads to colonic myenteric neurons injury via pro-inflammatory macrophages activation. Biochem Pharmacol 186, 114479.","journal-title":"Biochem Pharmacol"},{"key":"2391_CR17","doi-asserted-by":"publisher","first-page":"L716","DOI":"10.1152\/ajplung.00135.2006","volume":"292","author":"SC Gehen","year":"2007","unstructured":"Gehen, S.C., Vitiello, P.F., Bambara, R.A., Keng, P.C., and O\u2019Reilly, M.A. (2007). Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia. Am J Physiol Lung Cell Mol Physiol 292, L716\u2013L724.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"2391_CR18","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s00383-013-3364-y","volume":"29","author":"S Gfroerer","year":"2013","unstructured":"Gfroerer, S., and Rolle, U. (2013). Interstitial cells of Cajal in the normal human gut and in Hirschsprung disease. Pediatr Surg Int 29, 889\u2013897.","journal-title":"Pediatr Surg Int"},{"key":"2391_CR19","doi-asserted-by":"publisher","first-page":"4734","DOI":"10.1182\/blood-2009-03-213512","volume":"115","author":"M Gilchrist","year":"2010","unstructured":"Gilchrist, M., Henderson Jr, W.R., Morotti, A., Johnson, C.D., Nachman, A., Schmitz, F., Smith, K.D., and Aderem, A. (2010). A key role for ATF3 in regulating mast cell survival and mediator release. Blood 115, 4734\u20134741.","journal-title":"Blood"},{"key":"2391_CR20","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.tim.2017.05.004","volume":"25","author":"R Gresse","year":"2017","unstructured":"Gresse, R., Chaucheyras-Durand, F., Fleury, M.A., Van de Wiele, T., Forano, E., and Blanquet-Diot, S. (2017). Gut microbiota dysbiosis in postweaning piglets: understanding the keys to health. Trends Microbiol 25, 851\u2013873.","journal-title":"Trends Microbiol"},{"key":"2391_CR21","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1046\/j.1439-0396.2003.00405.x","volume":"87","author":"MS Hedemann","year":"2003","unstructured":"Hedemann, M.S., Hojsgaard, S., and Jensen, B.B. (2003). Small intestinal morphology and activity of intestinal peptidases in piglets around weaning. J Anim Physiol Anim Nutr 87, 32\u201341.","journal-title":"J Anim Physiol Anim Nutr"},{"key":"2391_CR22","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1136\/gut.21.11.933","volume":"21","author":"CS Higgens","year":"1980","unstructured":"Higgens, C.S., and Allan, R.N. (1980). Crohn\u2019s disease of the distal ileum. Gut 21, 933\u2013940.","journal-title":"Gut"},{"key":"2391_CR23","doi-asserted-by":"publisher","first-page":"4713","DOI":"10.1007\/s00018-021-03812-y","volume":"78","author":"AM Holland","year":"2021","unstructured":"Holland, A.M., Bon-Frauches, A.C., Keszthelyi, D., Melotte, V., and Boesmans, W. (2021). The enteric nervous system in gastrointestinal disease etiology. Cell Mol Life Sci 78, 4713\u20134733.","journal-title":"Cell Mol Life Sci"},{"key":"2391_CR24","doi-asserted-by":"publisher","first-page":"109012","DOI":"10.1016\/j.jneumeth.2020.109012","volume":"348","author":"Z Huang","year":"2021","unstructured":"Huang, Z., Liao, L., Wang, Z., Lu, Y., Yan, W., Cao, H., and Tan, B. (2021). An efficient approach for wholemount preparation of the myenteric plexus of rat colon. J Neurosci Methods 348, 109012.","journal-title":"J Neurosci Methods"},{"key":"2391_CR25","doi-asserted-by":"publisher","first-page":"G1","DOI":"10.1152\/ajpgi.90380.2008","volume":"296","author":"JD Huizinga","year":"2009","unstructured":"Huizinga, J.D., and Lammers, W.J.E.P. (2009). Gut peristalsis is governed by a multitude of cooperating mechanisms. Am J Physiol Gastrointest Liver Physiol 296, G1\u2013G8.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"2391_CR26","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s00441-019-03120-9","volume":"379","author":"S Iino","year":"2020","unstructured":"Iino, S., Horiguchi, K., and Horiguchi, S. (2020). c-Kit-stem cell factor signal-independent development of interstitial cells of Cajal in murine small intestine. Cell Tissue Res 379, 121\u2013129.","journal-title":"Cell Tissue Res"},{"key":"2391_CR27","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1091\/mbc.e08-05-0463","volume":"20","author":"O Islam","year":"2009","unstructured":"Islam, O., Gong, X., Rose-John, S., and Heese, K. (2009). Interleukin-6 and neural stem cells: more than gliogenesis. Mol Biol Cell 20, 188\u2013199.","journal-title":"Mol Biol Cell"},{"key":"2391_CR28","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1471-2199-7-30","volume":"7","author":"CG James","year":"2006","unstructured":"James, C.G., Woods, A., Underhill, T.M., and Beier, F. (2006). The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription. BMC Mol Biol 7, 30.","journal-title":"BMC Mol Biol"},{"key":"2391_CR29","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1758-5996-5-12","volume":"5","author":"QH Jin","year":"2013","unstructured":"Jin, Q.H., Shen, H.X., Wang, H., Shou, Q.Y., and Liu, Q. (2013). Curcumin improves expression of SCF\/c-kit through attenuating oxidative stress and NF-\u03baB activation in gastric tissues of diabetic gastroparesis rats. Diabetol Metab Syndr 5, 12.","journal-title":"Diabetol Metab Syndr"},{"key":"2391_CR30","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1017\/S0029665107005484","volume":"66","author":"JP Lalles","year":"2007","unstructured":"Lalles, J.P., Bosi, P., Smidt, H., and Stokes, C.R. (2007). Nutritional management of gut health in pigs around weaning. Proc Nutr Soc 66, 260\u2013268.","journal-title":"Proc Nutr Soc"},{"key":"2391_CR31","doi-asserted-by":"publisher","first-page":"992","DOI":"10.3390\/cells10050992","volume":"10","author":"JH Lin","year":"2021","unstructured":"Lin, J.H., Yu, Y.W., Chuang, Y.C., Lee, C.H., and Chen, C.C. (2021). ATF3-expressing large-diameter sensory afferents at acute stage as bio-signatures of persistent pain associated with lumbar radiculopathy. Cells 10, 992.","journal-title":"Cells"},{"key":"2391_CR32","doi-asserted-by":"publisher","first-page":"266","DOI":"10.3390\/ani9050266","volume":"9","author":"J Liu","year":"2019","unstructured":"Liu, J., Zhang, Y., Li, Y., Yan, H., and Zhang, H. (2019). L-tryptophan enhances intestinal integrity in diquat-challenged piglets associated with improvement of redox status and mitochondrial function. Animals 9, 266.","journal-title":"Animals"},{"key":"2391_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12885-015-1915-4","volume":"15","author":"B Lohberger","year":"2015","unstructured":"Lohberger, B., Leithner, A., Stuendl, N., Kaltenegger, H., Kullich, W., and Steinecker-Frohnwieser, B. (2015). Diacerein retards cell growth of chondrosarcoma cells at the G2\/M cell cycle checkpoint via cyclin B1\/CDK1 and CDK2 downregulation. BMC Cancer 15, 1.","journal-title":"BMC Cancer"},{"key":"2391_CR34","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love, M.I., Huber, W., and Anders, S. (2014). Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15, 550.","journal-title":"Genome Biol"},{"key":"2391_CR35","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.freeradbiomed.2013.07.036","volume":"66","author":"J Lu","year":"2014","unstructured":"Lu, J., and Holmgren, A. (2014). The thioredoxin antioxidant system. Free Radic Biol Med 66, 75\u201387.","journal-title":"Free Radic Biol Med"},{"key":"2391_CR36","doi-asserted-by":"crossref","unstructured":"Machado, C.C.A., Watanabe, P.S., Mendes, J.D.L., Pupim, A.C.E., Ortigoza, S.M., Bergoc, H.G., Nino, B.S.L., Gois, M.B., Garcia, J.L., Blackshaw, L.A., et al. (2021). Toxoplasma gondii infection impairs the colonic motility of rats due to loss of myenteric neurons. Neurogastroenterol Motil 33.","DOI":"10.1111\/nmo.13967"},{"key":"2391_CR37","doi-asserted-by":"publisher","first-page":"593","DOI":"10.3390\/genes11060593","volume":"11","author":"SF Mansilla","year":"2020","unstructured":"Mansilla, S.F., De La Vega, M.B., Calzetta, N.L., Siri, S.O., and Gottifredi, V. (2020). CDK-independent and PCNA-dependent functions of p21 in DNA replication. Genes 11, 593.","journal-title":"Genes"},{"key":"2391_CR38","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1111\/nmo.12828","volume":"28","author":"JE Medland","year":"2016","unstructured":"Medland, J.E., Pohl, C.S., Edwards, L.L., Frandsen, S., Bagley, K., Li, Y., and Moeser, A. J. (2016). Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses. Neurogastroenterol Motil 28, 1317\u20131329.","journal-title":"Neurogastroenterol Motil"},{"key":"2391_CR39","doi-asserted-by":"publisher","first-page":"254","DOI":"10.7555\/JBR.27.20130030","volume":"27","author":"S Nag","year":"2013","unstructured":"Nag, S., Qin, J., Srivenugopal, K.S., Wang, M., and Zhang, R. (2013). The MDM2-p53 pathway revisited. J Biomed Res 27, 254.","journal-title":"J Biomed Res"},{"key":"2391_CR40","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1016\/S0891-5849(01)00724-9","volume":"31","author":"J Nordberg","year":"2001","unstructured":"Nordberg, J., and Arner, E.S.J. (2001). Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31, 1287\u20131312.","journal-title":"Free Radic Biol Med"},{"key":"2391_CR41","doi-asserted-by":"publisher","first-page":"5161","DOI":"10.3390\/molecules26175161","volume":"26","author":"JT Pai","year":"2021","unstructured":"Pai, J.T., Hsu, M.W., Leu, Y.L., Chang, K.T., and Weng, M.S. (2021). Induction of G2\/ M cell cycle arrest via p38\/p21Waf1\/Cip1-dependent signaling pathway activation by bavachinin in non-small-cell lung cancer cells. Molecules 26, 5161.","journal-title":"Molecules"},{"key":"2391_CR42","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.bbrc.2013.11.121","volume":"443","author":"J Park","year":"2014","unstructured":"Park, J., Jang, H., Hwang, S.S., Kim, E.J., Kim, D.E., Oh, K.B., Kwon, D.J., Koh, J.T., Kimura, K., Inoue, H., et al. (2014). ER stress-inducible ATF3 suppresses BMP2- induced ALP expression and activation in MC3T3-E1 cells. Biochem Biophys Res Commun 443, 333\u2013338.","journal-title":"Biochem Biophys Res Commun"},{"key":"2391_CR43","doi-asserted-by":"publisher","first-page":"e123","DOI":"10.1093\/nar\/gkp596","volume":"37","author":"D Parkhomchuk","year":"2009","unstructured":"Parkhomchuk, D., Borodina, T., Amstislavskiy, V., Banaru, M., Hallen, L., Krobitsch, S., Lehrach, H., and Soldatov, A. (2009). Transcriptome analysis by strand-specific sequencing of complementary DNA. Nucleic Acids Res 37, e123.","journal-title":"Nucleic Acids Res"},{"key":"2391_CR44","doi-asserted-by":"publisher","first-page":"281","DOI":"10.5603\/FM.a2016.0002","volume":"75","author":"A Pasternak","year":"2016","unstructured":"Pasternak, A., Szura, M., Gil, K., and Matyja, A. (2016). Interstitial cells of Cajal \u2014 systematic review. Folia Morphol 75, 281\u2013286.","journal-title":"Folia Morphol"},{"key":"2391_CR45","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1097\/00004836-200202000-00004","volume":"34","author":"WA Qureshi","year":"2002","unstructured":"Qureshi, W.A. (2002). Gastrointestinal uses of botulinum toxin. J Clin Gastroenterol 34, 126\u2013128.","journal-title":"J Clin Gastroenterol"},{"key":"2391_CR46","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1007\/s11427-020-1721-5","volume":"64","author":"C Ran","year":"2021","unstructured":"Ran, C., Li, Y., Ma, X., Xie, Y., Xie, M., Zhang, Y., Zhou, W., Yang, Y., Zhang, Z., Zhou, L., et al. (2021). Interactions between commensal bacteria and viral infection: insights for viral disease control in farmed animals. Sci China Life Sci 64, 1437\u20131448.","journal-title":"Sci China Life Sci"},{"key":"2391_CR47","doi-asserted-by":"publisher","first-page":"2062","DOI":"10.1007\/s11427-021-2068-6","volume":"65","author":"W Ren","year":"2022","unstructured":"Ren, W., Yu, B., Yu, J., Zheng, P., Huang, Z., Luo, J., Mao, X., He, J., Yan, H., Wu, J., et al. (2022). Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets. Sci China Life Sci 65, 2062\u20132075.","journal-title":"Sci China Life Sci"},{"key":"2391_CR48","doi-asserted-by":"publisher","first-page":"e3418","DOI":"10.7717\/peerj.3418","volume":"5","author":"L Song","year":"2017","unstructured":"Song, L., Martinez, L., Zigmond, Z.M., Hernandez, D.R., Lassance-Soares, R.M., Selman, G., and Vazquez-Padron, R.I. (2017). c-Kit modifies the inflammatory status of smooth muscle cells. PeerJ 5, e3418.","journal-title":"PeerJ"},{"key":"2391_CR49","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1038\/s41575-020-0271-2","volume":"17","author":"NJ Spencer","year":"2020","unstructured":"Spencer, N.J., and Hu, H. (2020). Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility. Nat Rev Gastroenterol Hepatol 17, 338\u2013351.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"2391_CR50","doi-asserted-by":"publisher","first-page":"e01374","DOI":"10.1128\/mSystems.01374-20","volume":"6","author":"X Sun","year":"2021","unstructured":"Sun, X., Cui, Y., Su, Y., Gao, Z., Diao, X., Li, J., Zhu, X., Li, D., Li, Z., Wang, C., et al. (2021). Dietary fiber ameliorates lipopolysaccharide-induced intestinal barrier function damage in piglets by modulation of intestinal microbiome. mSystems 6, e01374\u201320.","journal-title":"mSystems"},{"key":"2391_CR51","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1182\/blood.V83.1.113.113","volume":"83","author":"H Tilg","year":"1994","unstructured":"Tilg, H., Trehu, E., Atkins, M.B., Dinarello, C.A., and Mier, J.W. (1994). Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 83, 113\u2013118.","journal-title":"Blood"},{"key":"2391_CR52","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1080\/10590500902885684","volume":"27","author":"A Valavanidis","year":"2009","unstructured":"Valavanidis, A., Vlachogianni, T., and Fiotakis, C. (2009). 8-Hydroxy-2\u2019-deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health Part C 27, 120\u2013139.","journal-title":"J Environ Sci Health Part C"},{"key":"2391_CR53","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.foodres.2017.08.054","volume":"101","author":"GE Vicentini","year":"2017","unstructured":"Vicentini, G.E., Martins, H.A., Fracaro, L., de Souza, S.R.G., da Silva Zanoni, K.P., Silva, T.N.X., Blegniski, F.P., Guarnier, F.A., and Zanoni, J.N. (2017). Does l-glutamine-supplemented diet extenuate NO-mediated damage on myenteric plexus of Walker 256 tumor-bearing rats? Food Res Int 101, 24\u201334.","journal-title":"Food Res Int"},{"key":"2391_CR54","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1097\/MIB.0000000000000193","volume":"21","author":"L Vitek","year":"2015","unstructured":"Vitek, L. (2015). Bile acid malabsorption in inflammatory bowel disease. Inflammatory Bowel Dis 21, 476\u2013483.","journal-title":"Inflammatory Bowel Dis"},{"key":"2391_CR55","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s00441-013-1775-7","volume":"356","author":"J Wei","year":"2014","unstructured":"Wei, J., Li, N., Xia, X., Chen, X., Peng, F., Besner, G.E., and Feng, J. (2014). Effects of lipopolysaccharide-induced inflammation on the interstitial cells of Cajal. Cell Tissue Res 356, 29\u201337.","journal-title":"Cell Tissue Res"},{"key":"2391_CR56","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.bbrc.2009.05.138","volume":"386","author":"CM Wu","year":"2009","unstructured":"Wu, C.M., Yang, C.W., Lee, Y.Z., Chuang, T.H., Wu, P.L., Chao, Y.S., and Lee, S.J. (2009). Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression. Biochem Biophys Res Commun 386, 140\u2013145.","journal-title":"Biochem Biophys Res Commun"},{"key":"2391_CR57","doi-asserted-by":"publisher","first-page":"761210","DOI":"10.3389\/fmicb.2021.761210","volume":"12","author":"H Yan","year":"2021","unstructured":"Yan, H., Wei, W., Hu, L., Zhang, Y., Zhang, H., and Liu, J. (2021). Reduced feeding frequency improves feed efficiency associated with altered fecal microbiota and bile acid composition in pigs. Front Microbiol 12, 761210.","journal-title":"Front Microbiol"},{"key":"2391_CR58","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.psj.2019.10.002","volume":"99","author":"HL Yan","year":"2020","unstructured":"Yan, H.L., Cao, S.C., Hu, Y.D., Zhang, H.F., and Liu, J.B. (2020). Effects of methylsulfonylmethane on growth performance, immunity, antioxidant capacity, and meat quality in Pekin ducks. Poultry Sci 99, 1069\u20131074.","journal-title":"Poultry Sci"},{"key":"2391_CR59","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1128\/JVI.72.1.330-338.1998","volume":"72","author":"L Yuan","year":"1998","unstructured":"Yuan, L., Kang, S.Y., Ward, L.A., To, T.L., and Saif, L.J. (1998). Antibody-secreting cell responses and protective immunity assessed in gnotobiotic pigs inoculated orally or intramuscularly with inactivated human rotavirus. J Virol 72, 330\u2013338.","journal-title":"J Virol"},{"key":"2391_CR60","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1007\/s11427-020-1908-2","volume":"65","author":"B Yue","year":"2022","unstructured":"Yue, B., Yang, H., Wu, J., Wang, J., Ru, W., Cheng, J., Huang, Y., Lan, X., Lei, C., and Chen, H. (2022). circSVIL regulates bovine myoblast development by inhibiting STAT1 phosphorylation. Sci China Life Sci 65, 376\u2013386.","journal-title":"Sci China Life Sci"},{"key":"2391_CR61","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1007\/s00438-018-1436-3","volume":"293","author":"S Zhang","year":"2018","unstructured":"Zhang, S., Chang, M., Zhou, Z., Dai, X., and Xu, Z. (2018). pDHS-ELM: computational predictor for plant DNase I hypersensitive sites based on extreme learning machines. Mol Genet Genomics 293, 1035\u20131049.","journal-title":"Mol Genet Genomics"},{"key":"2391_CR62","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1007\/s11427-020-1824-7","volume":"64","author":"Y Zhang","year":"2021","unstructured":"Zhang, Y., Sun, Y., Wu, Z., Xiong, X., Zhang, J., Ma, J., Xiao, S., Huang, L., and Yang, B. (2021). Subcutaneous and intramuscular fat transcriptomes show large differences in network organization and associations with adipose traits in pigs. Sci China Life Sci 64, 1732\u20131746.","journal-title":"Sci China Life Sci"},{"key":"2391_CR63","doi-asserted-by":"publisher","first-page":"3608","DOI":"10.7150\/ijbs.64003","volume":"17","author":"S Zhao","year":"2021","unstructured":"Zhao, S., Zhang, Y., Lu, X., Ding, H., Han, B., Song, X., Miao, H., Cui, X., Wei, S., Liu, W., et al. (2021). CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2\/Bax pathway. Int J Biol Sci 17, 3608\u20133621.","journal-title":"Int J Biol Sci"}],"container-title":["Science China Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-022-2391-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11427-022-2391-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-022-2391-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:09:07Z","timestamp":1707505747000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11427-022-2391-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,9]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["2391"],"URL":"https:\/\/doi.org\/10.1007\/s11427-022-2391-x","relation":{},"ISSN":["1674-7305","1869-1889"],"issn-type":[{"value":"1674-7305","type":"print"},{"value":"1869-1889","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,9]]},"assertion":[{"value":"1 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The author(s) declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interests"}}]}}