{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T09:40:18Z","timestamp":1740562818569,"version":"3.38.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci. China Life Sci."],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1007\/s11427-024-2645-y","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T02:50:11Z","timestamp":1736995811000},"page":"722-733","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["FHL2 deficiency aggravates Candida albicans infection through decreased myelopoiesis"],"prefix":"10.1007","volume":"68","author":[{"given":"Rongmei","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanchao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yimin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongxia","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weili","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingxiang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shangda","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanling","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengxia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"2645_CR1","doi-asserted-by":"publisher","first-page":"e1005882","DOI":"10.1371\/journal.ppat.1005882","volume":"12","author":"S Altmeier","year":"2016","unstructured":"Altmeier, S., Toska, A., Sparber, F., Teijeira, A., Halin, C., and LeibundGut-Landmann, S. (2016). IL-1 coordinates the neutrophil response to C. albicans in the oral mucosa. PLoS Pathog 12, e1005882.","journal-title":"PLoS Pathog"},{"key":"2645_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/S0925-4773(99)00314-7","volume":"91","author":"I Bach","year":"2000","unstructured":"Bach, I. (2000). The LIM domain: regulation by association. Mech Dev 91, 5\u201317.","journal-title":"Mech Dev"},{"key":"2645_CR3","doi-asserted-by":"publisher","first-page":"2742","DOI":"10.1172\/JCI24921","volume":"115","author":"S Bai","year":"2005","unstructured":"Bai, S. (2005). FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. J Clin Invest 115, 2742\u20132751.","journal-title":"J Clin Invest"},{"key":"2645_CR4","doi-asserted-by":"crossref","unstructured":"Baranek, T., Morello, E., Valayer, A., Aimar, R.F., Br\u00e9a, D., Henry, C., Besnard, A.G., Dalloneau, E., Guillon, A., Dequin, P.F., et al. (2017). FHL2 regulates natural killer cell development and activation during Streptococcus pneumoniae Infection. Front Immunol 8.","DOI":"10.3389\/fimmu.2017.00123"},{"key":"2645_CR5","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/sj.cdd.4401888","volume":"13","author":"V Bottero","year":"2006","unstructured":"Bottero, V., Withoff, S., and Verma, I.M. (2006). NF-\u03baB and the regulation of hematopoiesis. Cell Death Differ 13, 785\u2013797.","journal-title":"Cell Death Differ"},{"key":"2645_CR6","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1038\/ni.2987","volume":"15","author":"N Branzk","year":"2014","unstructured":"Branzk, N., Lubojemska, A., Hardison, S.E., Wang, Q., Gutierrez, M.G., Brown, G.D., and Papayannopoulos, V. (2014). Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol 15, 1017\u20131025.","journal-title":"Nat Immunol"},{"key":"2645_CR7","doi-asserted-by":"publisher","first-page":"338","DOI":"10.2353\/ajpath.2006.060312","volume":"169","author":"D Bryder","year":"2006","unstructured":"Bryder, D., Rossi, D.J., and Weissman, I.L. (2006). Hematopoietic stem cells. Am J Pathol 169, 338\u2013346.","journal-title":"Am J Pathol"},{"key":"2645_CR8","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1182\/blood.2022016835","volume":"141","author":"F Caiado","year":"2023","unstructured":"Caiado, F., Kovtonyuk, L.V., Gonullu, N.G., Fullin, J., Boettcher, S., and Manz, M.G. (2023). Aging drives Tet2+\/\u2212 clonal hematopoiesis via IL-1 signaling. Blood 141, 886\u2013903.","journal-title":"Blood"},{"key":"2645_CR9","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41417-018-0027-0","volume":"26","author":"Z Cheng","year":"2018","unstructured":"Cheng, Z., Dai, Y., Pang, Y., Jiao, Y., Zhao, H., Zhang, Z., Qin, T., Hu, N., Zhang, Y., Ke, X., et al. (2018). Enhanced expressions of FHL2 and iASPP predict poor prognosis in acute myeloid leukemia. Cancer Gene Ther 26, 17\u201325.","journal-title":"Cancer Gene Ther"},{"key":"2645_CR10","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1007\/s00018-017-2724-5","volume":"75","author":"Y Chiba","year":"2017","unstructured":"Chiba, Y., Mizoguchi, I., Hasegawa, H., Ohashi, M., Orii, N., Nagai, T., Sugahara, M., Miyamoto, Y., Xu, M., Owaki, T., et al. (2017). Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases. Cell Mol Life Sci 75, 1363\u20131376.","journal-title":"Cell Mol Life Sci"},{"key":"2645_CR11","doi-asserted-by":"publisher","first-page":"6699","DOI":"10.1038\/s41467-021-27034-9","volume":"12","author":"X Ding","year":"2021","unstructured":"Ding, X., Kambara, H., Guo, R., Kanneganti, A., Acosta-Zaldfvar, M., Li, J., Liu, F., Bei, T., Qi, W., Xie, X., et al. (2021). Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages. Nat Commun 12, 6699.","journal-title":"Nat Commun"},{"key":"2645_CR12","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.immuni.2017.05.009","volume":"46","author":"J Dom\u00ednguez-Andr\u00e9s","year":"2017","unstructured":"Dom\u00ednguez-Andr\u00e9s, J., Feo-Lucas, L., Minguito de la Escalera, M., Gonz\u00e1lez, L., L\u00f3pez-Bravo, M., and Ardavm, C. (2017). Inflammatory Ly6Chigh monocytes protect against candidiasis through IL-15-driven NK cell\/neutrophil activation. Immunity 46, 1059\u20131072.e4.","journal-title":"Immunity"},{"key":"2645_CR13","doi-asserted-by":"publisher","first-page":"eabb1069","DOI":"10.1126\/scitranslmed.abb1069","volume":"13","author":"Y Fan","year":"2021","unstructured":"Fan, Y., Teng, Y., Loison, F., Pang, A., Kasorn, A., Shao, X., Zhang, C., Ren, Q., Yu, H., Zheng, Y., et al. (2021). Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion. Sci Transl Med 13, eabb1069.","journal-title":"Sci Transl Med"},{"key":"2645_CR14","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/nature07965","volume":"459","author":"O Gross","year":"2009","unstructured":"Gross, O., Poeck, H., Bscheider, M., Dostert, C., Hannesschl\u00e4ger, N., Endres, S., Hartmann, G., Tardivel, A., Schweighoffer, E., Tybulewicz, V., et al. (2009). Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 459, 433\u2013436.","journal-title":"Nature"},{"key":"2645_CR15","doi-asserted-by":"publisher","unstructured":"Guo, R., Zhang, X., Wu, P., Gao, R., Fan, Y., Holton, K.M., Shi, Q., Xie, X., Ren, Q., Park, S.Y., et al. (2022). IL1R1-mediated trained emergency myelopoiesis maximizes hematopoietic fitness in recurrent and sustained infections. SSRN J doi: https:\/\/doi.org\/10.2139\/ssrn.4034889.","DOI":"10.2139\/ssrn.4034889"},{"key":"2645_CR16","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1084\/jem.172.2.431","volume":"172","author":"DE Harrison","year":"1990","unstructured":"Harrison, D.E., Stone, M., and Astle, C.M. (1990). Effects of transplantation on the primitive immunohematopoietic stem cell. J Exp Med 172, 431\u2013437.","journal-title":"J Exp Med"},{"key":"2645_CR17","doi-asserted-by":"publisher","first-page":"3546","DOI":"10.1073\/pnas.0914351107","volume":"107","author":"H Hattori","year":"2010","unstructured":"Hattori, H., Subramanian, K.K., Sakai, J., Jia, Y., Li, Y., Porter, T.F., Loison, F., Sarraj, B., Kasorn, A., Jo, H., et al. (2010). Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc Natl Acad Sci USA 107, 3546\u20133551.","journal-title":"Proc Natl Acad Sci USA"},{"key":"2645_CR18","doi-asserted-by":"publisher","first-page":"e20200560","DOI":"10.1084\/jem.20200560","volume":"218","author":"KC Higa","year":"2021","unstructured":"Higa, K.C., Goodspeed, A., Chavez, J.S., De Dominici, M., Danis, E., Zaberezhnyy, V., Rabe, J.L., Tenen, D.G., Pietras, E.M., and DeGregori, J. (2021). Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. J Exp Med 218, e20200560.","journal-title":"J Exp Med"},{"key":"2645_CR19","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.chom.2009.05.002","volume":"5","author":"AG Hise","year":"2009","unstructured":"Hise, A.G., Tomalka, J., Ganesan, S., Patel, K., Hall, B.A., Brown, G.D., and Fitzgerald, K.A. (2009). An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe 5, 487\u2013497.","journal-title":"Cell Host Microbe"},{"key":"2645_CR20","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1038\/leu.2014.254","volume":"29","author":"Y Hou","year":"2014","unstructured":"Hou, Y., Wang, X., Li, L., Fan, R., Chen, J., Zhu, T., Li, W., Jiang, Y., Mittal, N., Wu, W., et al. (2014). FHL2 regulates hematopoietic stem cell functions under stress conditions. Leukemia 29, 615\u2013624.","journal-title":"Leukemia"},{"key":"2645_CR21","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1038\/nm1388","volume":"12","author":"K Ito","year":"2006","unstructured":"Ito, K., Hirao, A., Arai, F., Takubo, K., Matsuoka, S., Miyamoto, K., Ohmura, M., Naka, K., Hosokawa, K., Ikeda, Y., et al. (2006). Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12, 446\u2013451.","journal-title":"Nat Med"},{"key":"2645_CR22","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1038\/nrm1499","volume":"5","author":"JL Kadrmas","year":"2004","unstructured":"Kadrmas, J.L., and Beckerle, M.C. (2004). The LIM domain: from the cytoskeleton to the nucleus. Nat Rev Mol Cell Biol 5, 920\u2013931.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2645_CR23","first-page":"55","volume":"27","author":"K Kleiber","year":"2007","unstructured":"Kleiber, K., Strebhardt, K., and Martin, B.T. (2007). The biological relevance of FHL2 in tumour cells and its role as a putative cancer target. Anticancer Res, 27, 55\u201362.","journal-title":"Anticancer Res"},{"key":"2645_CR24","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1182\/blood.2021011570","volume":"139","author":"LV Kovtonyuk","year":"2022","unstructured":"Kovtonyuk, L.V., Caiado, F., Garcia-Martin, S., Manz, E.M., Helbling, P., Takizawa, H., Boettcher, S., Al-Shahrour, F., Nombela-Arrieta, C., Slack, E., et al. (2022). IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice. Blood 139, 44\u201358.","journal-title":"Blood"},{"key":"2645_CR25","doi-asserted-by":"publisher","first-page":"3098","DOI":"10.1002\/eji.201545627","volume":"45","author":"K Kurakula","year":"2015","unstructured":"Kurakula, K., Vos, M., van Eijk, M., Smits, H.H., and de Vries, C.J.M. (2015). LIM-only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation. Eur J Immunol 45, 3098\u20133106.","journal-title":"Eur J Immunol"},{"key":"2645_CR26","doi-asserted-by":"publisher","first-page":"15201","DOI":"10.1074\/jbc.M800708200","volume":"283","author":"C Labalette","year":"2008","unstructured":"Labalette, C., Nou\u00ebt, Y., Sobczak-Thepot, J., Armengol, C., Levillayer, F., Gendron, M. C., Renard, C.A., Regnault, B., Chen, J., Buendia, M.A., et al. (2008). The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. J Biol Chem 283, 15201\u201315208.","journal-title":"J Biol Chem"},{"key":"2645_CR27","doi-asserted-by":"publisher","first-page":"4930","DOI":"10.1182\/blood-2008-06-161414","volume":"113","author":"Y Li","year":"2009","unstructured":"Li, Y., Jia, Y., Pichavant, M., Loison, F., Sarraj, B., Kasorn, A., You, J., Robson, B.E., Umetsu, D.T., Mizgerd, J.P., et al. (2009). Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. Blood 113, 4930\u20134941.","journal-title":"Blood"},{"key":"2645_CR28","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1038\/nri3660","volume":"14","author":"MG Manz","year":"2014","unstructured":"Manz, M.G., and Boettcher, S. (2014). Emergency granulopoiesis. Nat Rev Immunol 14, 302\u2013314.","journal-title":"Nat Rev Immunol"},{"key":"2645_CR29","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1016\/j.ajpath.2018.02.004","volume":"188","author":"D Masemann","year":"2018","unstructured":"Masemann, D., Leite Dantas, R., Sitnik, S., Schied, T., Nordhoff, C., Ludwig, S., and Wixler, V. (2018). The four-and-a-half LIM domain protein 2 supports influenza A virus-induced lung inflammation by restricting the host adaptive immune response. Am J Pathol 188, 1236\u20131245.","journal-title":"Am J Pathol"},{"key":"2645_CR30","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/BF02171754","volume":"4","author":"RL Monroy","year":"1992","unstructured":"Monroy, R.L., Skelly, R.R., Davis, T.A., and MacVittie, T.J. (1992). Therapeutic evaluation of interleukin-1 for stimulation of hematopoiesis in primates after autologous bone marrow transplantation. Biotherapy 4, 97\u2013108.","journal-title":"Biotherapy"},{"key":"2645_CR31","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1111\/j.1462-5822.2012.01787.x","volume":"14","author":"C Nordhoff","year":"2012","unstructured":"Nordhoff, C., Hillesheim, A., Walter, B.M., Haasbach, E., Planz, O., Ehrhardt, C., Ludwig, S., and Wixler, V. (2012). The adaptor protein FHL2 enhances the cellular innate immune response to influenza A virus infection. Cell Microbiol 14, 1135\u20131147.","journal-title":"Cell Microbiol"},{"key":"2645_CR32","doi-asserted-by":"publisher","first-page":"4204","DOI":"10.4049\/jimmunol.140.12.4204","volume":"140","author":"P Morrissey","year":"1988","unstructured":"Morrissey, P., Charrier, K., Bressler, L., and Alpert, A. (1988). The influence of IL-1 treatment on the reconstitution of the hemopoietic and immune systems after sublethal radiation. J Immunol 140, 4204\u20134210.","journal-title":"J Immunol"},{"key":"2645_CR33","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/ncb3346","volume":"18","author":"EM Pietras","year":"2016","unstructured":"Pietras, E.M., Mirantes-Barbeito, C., Fong, S., Loeffler, D., Kovtonyuk, L.V., Zhang, S. Y., Lakshminarasimhan, R., Chin, C.P., Techner, J.M., Will, B., et al. (2016). Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol 18, 607\u2013618.","journal-title":"Nat Cell Biol"},{"key":"2645_CR34","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1038\/ni.2052","volume":"12","author":"A Prasad","year":"2011","unstructured":"Prasad, A., Jia, Y., Chakraborty, A., Li, Y., Jain, S.K., Zhong, J., Roy, S.G., Loison, F., Mondal, S., Sakai, J., et al. (2011). Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling. Nat Immunol 12, 752\u2013760.","journal-title":"Nat Immunol"},{"key":"2645_CR35","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1038\/leu.2009.78","volume":"23","author":"Z Qian","year":"2009","unstructured":"Qian, Z., Mao, L., Fernald, A.A., Yu, H., Luo, R., Jiang, Y., Anastasi, J., Valk, P.J., Delwel, R., and Le Beau, M.M. (2009). Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo. Leukemia 23, 1650\u20131657.","journal-title":"Leukemia"},{"key":"2645_CR36","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/35102167","volume":"414","author":"T Reya","year":"2001","unstructured":"Reya, T., Morrison, S.J., Clarke, M.F., and Weissman, I.L. (2001). Stem cells, cancer, and cancer stem cells. Nature 414, 105\u2013111.","journal-title":"Nature"},{"key":"2645_CR37","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.it.2011.06.008","volume":"32","author":"CD Sadik","year":"2011","unstructured":"Sadik, C.D., Kim, N.D., and Luster, A.D. (2011). Neutrophils cascading their way to inflammation. Trends Immunol 32, 452\u2013460.","journal-title":"Trends Immunol"},{"key":"2645_CR38","doi-asserted-by":"publisher","first-page":"28641","DOI":"10.1074\/jbc.M312894200","volume":"279","author":"T Samson","year":"2004","unstructured":"Samson, T., Smyth, N., Janetzky, S., Wendler, O., M\u00fcller, J.M., Schule, R., von der Mark, H., von der Mark, K., and Wixler, V. (2004). The LIM-only proteins FHL2 and FHL3 interact with \u03b1- and \u03b2-subunits of the muscle \u03b17\u03b21 integrin receptor. J Biol Chem 279, 28641\u201328652.","journal-title":"J Biol Chem"},{"key":"2645_CR39","doi-asserted-by":"publisher","first-page":"4546","DOI":"10.4049\/jimmunol.1103007","volume":"189","author":"S Satake","year":"2012","unstructured":"Satake, S., Hirai, H., Hayashi, Y., Shime, N., Tamura, A., Yao, H., Yoshioka, S., Miura, Y., Inaba, T., Fujita, N., et al. (2012). C\/EBP\u03b2 is involved in the amplification of early granulocyte precursors during candidemia-induced \u201cemergency\u201d granulopoiesis. J Immunol 189, 4546\u20134555.","journal-title":"J Immunol"},{"key":"2645_CR40","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1038\/nri3070","volume":"11","author":"C Shi","year":"2011","unstructured":"Shi, C., and Pamer, E.G. (2011). Monocyte recruitment during infection and inflammation. Nat Rev Immunol 11, 762\u2013774.","journal-title":"Nat Rev Immunol"},{"key":"2645_CR41","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/0092-8674(86)90781-6","volume":"45","author":"ER Stanley","year":"1986","unstructured":"Stanley, E.R., Bartocci, A., Patinkin, D., Rosendaal, M., and Bradley, T.R. (1986). Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1. Cell 45, 667\u2013674.","journal-title":"Cell"},{"key":"2645_CR42","doi-asserted-by":"publisher","first-page":"5015","DOI":"10.1182\/blood-2013-02-486142","volume":"121","author":"SJ Stein","year":"2013","unstructured":"Stein, S.J., and Baldwin, A.S. (2013). Deletion of the NF-\u03baB subunit p65\/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function. Blood 121, 5015\u20135024.","journal-title":"Blood"},{"key":"2645_CR43","doi-asserted-by":"publisher","first-page":"2991","DOI":"10.1182\/blood-2011-12-380113","volume":"119","author":"H Takizawa","year":"2012","unstructured":"Takizawa, H., Boettcher, S., and Manz, M.G. (2012). Demand-adapted regulation of early hematopoiesis in infection and inflammation. Blood 119, 2991\u20133002.","journal-title":"Blood"},{"key":"2645_CR44","doi-asserted-by":"publisher","first-page":"2553","DOI":"10.1007\/s11427-022-2310-x","volume":"66","author":"SQ Tang","year":"2023","unstructured":"Tang, S.Q., Xing, T., Lyu, Z.S., Guo, L.P., Liang, M., Li, C.Y., Zhang, Y.Y., Wang, Y., Xu, L.P., Zhang, X.H., et al. (2023). Repair of dysfunctional bone marrow endothelial cells alleviates aplastic anemia. Sci China Life Sci 66, 2553\u20132570.","journal-title":"Sci China Life Sci"},{"key":"2645_CR45","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.bbamcr.2015.11.002","volume":"1863","author":"MK Tran","year":"2016","unstructured":"Tran, M.K., Kurakula, K., Koenis, D.S., and de Vries, C.J.M. (2016). Protein-protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease. Biochim Biophys Acta 1863, 219\u2013228.","journal-title":"Biochim Biophys Acta"},{"key":"2645_CR46","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.3389\/fimmu.2017.01089","volume":"8","author":"S Walachowski","year":"2017","unstructured":"Walachowski, S., Tabouret, G., Fabre, M., and Foucras, G. (2017). Molecular analysis of a short-term model of \u03b2-glucans-trained immunity highlights the accessory contribution of GM-CSF in priming mouse macrophages response. Front Immunol 8, 1089.","journal-title":"Front Immunol"},{"key":"2645_CR47","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/imr.12302","volume":"266","author":"MC Walsh","year":"2015","unstructured":"Walsh, M.C., Lee, J.E., and Choi, Y. (2015). Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system. Immunol Rev 266, 72\u201392.","journal-title":"Immunol Rev"},{"key":"2645_CR48","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1038\/nrm3184","volume":"12","author":"LD Wang","year":"2011","unstructured":"Wang, L.D., and Wagers, A.J. (2011). Dynamic niches in the origination and differentiation of haematopoietic stem cells. Nat Rev Mol Cell Biol 12, 643\u2013655.","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2645_CR49","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.immuni.2017.02.013","volume":"46","author":"A Warnatsch","year":"2017","unstructured":"Warnatsch, A., Tsourouktsoglou, T.D., Branzk, N., Wang, Q., Reincke, S., Herbst, S., Gutierrez, M., and Papayannopoulos, V. (2017). Reactive oxygen species localization programs inflammation to clear microbes of different size. Immunity 46, 421\u2013432.","journal-title":"Immunity"},{"key":"2645_CR50","doi-asserted-by":"publisher","first-page":"7799","DOI":"10.1096\/fj.201802765RR","volume":"33","author":"V Wixler","year":"2019","unstructured":"Wixler, V. (2019). The role of FHL2 in wound healing and inflammation. FASEB J 33, 7799\u20137809.","journal-title":"FASEB J"},{"key":"2645_CR51","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.cyto.2012.04.044","volume":"59","author":"CH Wong","year":"2012","unstructured":"Wong, C.H., Mak, G.W.Y., Li, M.S., and Tsui, S.K.W. (2012). The LIM-only protein FHL2 regulates interleukin-6 expression through p38 MAPK mediated NF-\u03baB pathway in muscle cells. Cytokine 59, 286\u2013293.","journal-title":"Cytokine"},{"key":"2645_CR52","doi-asserted-by":"publisher","first-page":"e1008096","DOI":"10.1371\/journal.ppat.1008096","volume":"15","author":"SY Wu","year":"2019","unstructured":"Wu, S.Y., Weng, C.L., Jheng, M.J., Kan, H.W., Hsieh, S.T., Liu, F.T., and Wu-Hsieh, B. A. (2019).Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2. PLoS Pathog 15, e1008096.","journal-title":"PLoS Pathog"},{"key":"2645_CR53","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.3390\/ijms18071484","volume":"18","author":"WR Xia","year":"2017","unstructured":"Xia, W.R., Fu, W., Wang, Q., Zhu, X., Xing, W.W., Wang, M., Xu, D.Q., and Xu, D.G. (2017). Autophagy induced FHL2 upregulation promotes IL-6 production by activating the NF-\u03baB pathway in mouse aortic endothelial cells after exposure to PM2.5. Int J Mol Sci 18, 1484.","journal-title":"Int J Mol Sci"},{"key":"2645_CR54","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1038\/s41590-020-0736-z","volume":"21","author":"X Xie","year":"2020","unstructured":"Xie, X., Shi, Q., Wu, P., Zhang, X., Kambara, H., Su, J., Yu, H., Park, S.Y., Guo, R., Ren, Q., et al. (2020). Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection. Nat Immunol 21, 1119\u20131133.","journal-title":"Nat Immunol"}],"container-title":["Science China Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-024-2645-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11427-024-2645-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11427-024-2645-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T08:56:50Z","timestamp":1740560210000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11427-024-2645-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":54,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["2645"],"URL":"https:\/\/doi.org\/10.1007\/s11427-024-2645-y","relation":{},"ISSN":["1674-7305","1869-1889"],"issn-type":[{"type":"print","value":"1674-7305"},{"type":"electronic","value":"1869-1889"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"1 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of Interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}