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This study received approval from the Institutional Review Board of the Center for Reproductive Medicine, Shandong University (approval number 2016IRB14) and the Reproductive and Genetic Hospital of CITIC-XIANGYA (approval number LL-SC-2021-034). All the research involving human research participants was performed in accordance with the Declaration of Helsinki.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}