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All specimens were collected after obtaining written informed consent from the study participants. The study was conducted in accordance with the Declaration of Helsinki. The study was approved by the Ethics Committee of the Third Affiliated Hospital of Sun Yat-sen University (Guangzhou, China; approval ID: (2018) 02-384-01). All animal experimental procedures were performed in accordance with the approval of the Animal Care Ethics Committee of The First Affiliated Hospital, Guangxi Medical University (2024-D278-01).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}