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The approval of animal experimental protocols was acquired from the Institutional Review Board and the Animal Care and Use Committee of Sun Yat-sen University (SYSU-IACUC-2023-001824). All procedures involving human tissues were reviewed and approved by the internal review and ethics boards of Sun Yat-sen Memorial Hospital (SYSKY-2025-1043-01)","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}