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Experimental protocols were reviewed and approved by the Institutional Animal Care and Use Committee of the Suzhou Institute of Systems Medicine (No. ISM-IACUC-AUP-202403025). Age-matched female mice were used in all experiments and randomly assigned to different experimental groups. All experiments were performed in accordance with the approved protocol and other relevant guidelines and regulations.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}