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This study strictly adhered to the guidelines for experimental animal welfare and ethics, and all animal experimental protocols were approved by the Institutional Animal Care and Use Committee of the Hangzhou Institute of Medicine, Chinese Academy of Sciences (Ethics Approval No. AP2025-08-0572). This study was approved by the Ethics Committee of Hangzhou First People\u2019s Hospital (Approval No. 2026ZN166-1), and all methods were carried out under relevant guidelines and regulations.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance and ethics"}}]}}