{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T11:39:43Z","timestamp":1792669183993,"version":"4.5.0"},"reference-count":121,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["DA013137"],"award-info":[{"award-number":["DA013137"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH106392"],"award-info":[{"award-number":["MH106392"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["HD043680"],"award-info":[{"award-number":["HD043680"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["ND100624"],"award-info":[{"award-number":["ND100624"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neuroimmune Pharmacol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s11481-020-09928-5","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T12:02:41Z","timestamp":1591963361000},"page":"715-728","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["HIV Infection and Neurocognitive Disorders in the Context of Chronic Drug Abuse: Evidence for Divergent Findings Dependent upon Prior Drug History"],"prefix":"10.1007","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1841-9139","authenticated-orcid":false,"given":"Jessica M.","family":"Illenberger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-3503","authenticated-orcid":false,"given":"Steven B.","family":"Harrod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6508-1329","authenticated-orcid":false,"given":"Charles F.","family":"Mactutus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7816-1806","authenticated-orcid":false,"given":"Kristen A.","family":"McLaurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6483-523X","authenticated-orcid":false,"given":"Asha","family":"Kallianpur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3908-8313","authenticated-orcid":false,"given":"Rosemarie M.","family":"Booze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"issue":"7","key":"9928_CR1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/nn872","volume":"5","author":"S Ahmed","year":"2002","unstructured":"Ahmed S, Kenny P, Koob G, Markou A (2002) Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nat Neurosci 5(7):625\u2013626","journal-title":"Nat Neurosci"},{"issue":"3","key":"9928_CR2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.neulet.2005.10.095","volume":"395","author":"M Aksenova","year":"2006","unstructured":"Aksenova M, Silvers J, Aksenov M, Nath A, Ray P, Mactutus C, Booze R (2006) HIV-1 tat neurotoxicity in primary cultures of rat midbrain fetal neurons: changes in dopamine transporter binding and immunoreactivity. Neurosci Lett 395(3):235\u2013239","journal-title":"Neurosci Lett"},{"issue":"1","key":"9928_CR3","first-page":"32","volume":"25","author":"A Alakkas","year":"2019","unstructured":"Alakkas A, Ellis R, Watson C, Umlauf A, Heaton R, Letendre S et al (2019) White matter damage, neuroinflammation, and neuronal integrity in HAND. J Neuro-Oncol 25(1):32\u201341","journal-title":"J Neuro-Oncol"},{"key":"9928_CR4","doi-asserted-by":"crossref","unstructured":"Barrientos C, Knowland D, Wu M, Lilascharoen V. Huang K, Malenka R, Lim B (2018) Cocaine-induced structural plasticity in input regions to distinct cell types in nucleus Accumbens. Biol Psychiatry 84(12):893\u2013904","DOI":"10.1016\/j.biopsych.2018.04.019"},{"issue":"11","key":"9928_CR5","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1038\/nn1584","volume":"8","author":"A Bechara","year":"2005","unstructured":"Bechara A (2005) Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci 8(11):1458\u20131463","journal-title":"Nat Neurosci"},{"issue":"4","key":"9928_CR6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.31887\/DCNS.2016.18.4\/jbecker","volume":"18","author":"JB Becker","year":"2016","unstructured":"Becker JB (2016) Sex differences in addiction. Dialogues Clin Neurosci 18(4):395\u2013402","journal-title":"Dialogues Clin Neurosci"},{"issue":"2\u20133","key":"9928_CR7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1159\/000150539","volume":"40","author":"J Berger","year":"1997","unstructured":"Berger J, Nath A (1997) HIV dementia and the basal ganglia. Intervirology 40(2\u20133):122\u2013131","journal-title":"Intervirology"},{"issue":"1","key":"9928_CR8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00002030-199401000-00010","volume":"8","author":"J Berger","year":"1994","unstructured":"Berger J, Kumar M, Kumar A, Fernandez J, Levin B (1994) Cerebrospinal fluid dopamine in HIV-1 infection. AIDS 8(1):67\u201371","journal-title":"AIDS"},{"issue":"3","key":"9928_CR9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00213-006-0578-x","volume":"191","author":"K Berridge","year":"2007","unstructured":"Berridge K (2007) The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology 191(3):391\u2013431","journal-title":"Psychopharmacology"},{"key":"9928_CR10","doi-asserted-by":"crossref","first-page":"7869","DOI":"10.1038\/s41598-018-25109-0","volume":"8","author":"S Bertrand","year":"2018","unstructured":"Bertrand S, Mactutus C, Harrod S, Moran L, Booze R (2018) HIV-1 proteins dysregulate motivational processes and dopamine circuitry. Sci Rep 8:7869","journal-title":"Sci Rep"},{"issue":"2","key":"9928_CR11","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1037\/h0099916","volume":"2","author":"A Blume","year":"2012","unstructured":"Blume A (2012) Negative reinforcement and substance abuse: using a behavioral conceptualization to enhance treatment. Behav Anal Today 2(2):86\u201390","journal-title":"Behav Anal Today"},{"issue":"1","key":"9928_CR12","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0892-0362(96)00180-8","volume":"19","author":"RM Booze","year":"1997","unstructured":"Booze RM, Lehner AF, Wallace DR, Welch MA, Mactutus CF (1997) Dose-response cocaine pharmacokinetics and metabolite profile following intravenous administration and arterial sampling in unanesthetized, freely moving male rats. Neurotoxicol Teratol 19(1):7\u201315","journal-title":"Neurotoxicol Teratol"},{"issue":"2","key":"9928_CR13","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1600-0560.1982.tb01045.x","volume":"9","author":"J Bruckner","year":"1982","unstructured":"Bruckner J, Jiang W, Ho B, Levy B (1982) Histopathological evaluation of cocaine-induced skin lesions in the rat. J Cutan Pathol 9(2):83\u201395","journal-title":"J Cutan Pathol"},{"issue":"4","key":"9928_CR14","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s11481-011-9297-0","volume":"6","author":"S Buch","year":"2011","unstructured":"Buch S, Yao H, Guo M, Mori T, Su TP, Wang J (2011) Cocaine and HIV-1 interplay: molecular mechanisms of action and addiction. J NeuroImmune Pharmacol 6(4):503\u2013515","journal-title":"J NeuroImmune Pharmacol"},{"issue":"6","key":"9928_CR15","first-page":"1337","volume":"64","author":"B Bystrowska","year":"2012","unstructured":"Bystrowska B, Adamczyk P, Moniczewski A, Zaniewska M, Fuxe K, Filip M (2012) LC\/MS\/MS evaluation of cocaine and its metabolites in different brain areas, peripheral organs and plasma in cocaine self-administering rats. Phamracol Rep 64(6):1337\u20131349","journal-title":"Phamracol Rep"},{"issue":"4","key":"9928_CR16","doi-asserted-by":"crossref","first-page":"412","DOI":"10.2174\/1570162X14666160324125158","volume":"14","author":"Y Cai","year":"2016","unstructured":"Cai Y, Yang L, Callen S, Buch S (2016) Multiple faceted roles of cocaine in potentiation of HAND. Curr HIV Res 14(4):412\u2013416","journal-title":"Curr HIV Res"},{"issue":"10","key":"9928_CR17","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1073\/pnas.1521238113","volume":"113","author":"E Calipari","year":"2016","unstructured":"Calipari E, Bagot R, Purushothaman I, Davidson T, Yorgason J, Pena C et al (2016) In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proc Natl Acad Sci U S A 113(10):2726\u20132731","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"9928_CR18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s10461-005-9056-4","volume":"10","author":"C Carey","year":"2006","unstructured":"Carey C, Woods S, Rippeth J, Gonzalez R, Heaton R, Grant I (2006) Additive deleterious effects of methamphetamine dependence and immunosuppression on neuropsychological functioning in HIV infection. AIDS Behav 10(2):185\u2013190","journal-title":"AIDS Behav"},{"issue":"2","key":"9928_CR19","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.neuroimage.2008.05.011","volume":"42","author":"L Chang","year":"2008","unstructured":"Chang L, Wang G, Volkow N, Ernst T, Telang F, Logan J, Fowler J (2008) Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse. Neuroimage 42(2):869\u2013878","journal-title":"Neuroimage"},{"issue":"2","key":"9928_CR20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1176\/appi.ajp.162.2.361","volume":"162","author":"L Chang","year":"2005","unstructured":"Chang L, Ernst T, Speck O, Grob C (2005) Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry 162(2):361\u2013369","journal-title":"Am J Psychiatry"},{"issue":"3","key":"9928_CR21","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/glia.23081","volume":"65","author":"N Chen","year":"2017","unstructured":"Chen N, Partridge A, Sell C, Torres C, Martin-Garcia J (2017) Fate of microglia during HIV-1 infection: from activation to senescence? Glia 65(3):431\u2013446","journal-title":"Glia"},{"issue":"6","key":"9928_CR22","first-page":"350","volume":"10","author":"LA Cysique","year":"2004","unstructured":"Cysique LA, Maruff P, Brew BJ (2004) Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus-infected\/acquired immunodeficiency syndrome (HIV\/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: a combined study of two cohorts. J Neuro-Oncol 10(6):350\u2013357","journal-title":"J Neuro-Oncol"},{"issue":"4","key":"9928_CR23","first-page":"540","volume":"25","author":"A Denton","year":"2019","unstructured":"Denton A, Samaranayake S, Kirchner K, Roscoe R, Berger S, Harrod S et al (2019) Selective monoaminergic and histaminergic circuit dysregulation following long-term HIV-1 protein exposure. J Neuro-Oncol 25(4):540\u2013550","journal-title":"J Neuro-Oncol"},{"issue":"15","key":"9928_CR24","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1212\/WNL.0b013e31828c2e9e","volume":"80","author":"P Desplats","year":"2013","unstructured":"Desplats P, Dumaop W, Smith D, Adame AE, Letendre S, Ellis R et al (2013) Molecular and pathologic insights from latent HIV-1 infection in the human brain. Neurology 80(15):1415\u20131423","journal-title":"Neurology"},{"issue":"5","key":"9928_CR25","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/QAD.0000000000000580","volume":"29","author":"AM Dickens","year":"2015","unstructured":"Dickens AM, Anthony DC, Deutsch R, Mielke MM, Claridge TD, Grant I, Franklin D, Rosario D, Marcotte T, Letendre S, McArthur J, Haughey NJ (2015) Cerebrospinal fluid metabolomics implicate bioenergetic adaption as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. AIDS 29(5):559\u2013569","journal-title":"AIDS"},{"issue":"1","key":"9928_CR26","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/glia.440070113","volume":"7","author":"D Dickson","year":"1993","unstructured":"Dickson D, Lee S, Mattiaca L, Yen S, Brosnan C (1993) Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer\u2019s disease. Glia 7(1):75\u201383","journal-title":"Glia"},{"key":"9928_CR27","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.pbb.2009.01.004","volume":"92","author":"Z Ding","year":"2009","unstructured":"Ding Z, Liu W, Engleman EA, Rodd ZA, McBride WJ (2009) Differential effects of dopamine D2 and GABAA receptor antagonists on dopamine neurons between the anterior and posterior ventral tegmental area of female Wistar rats. Pharmacol Biochem Be 92:404\u2013412","journal-title":"Pharmacol Biochem Be"},{"issue":"31","key":"9928_CR28","doi-asserted-by":"crossref","first-page":"11017","DOI":"10.1073\/pnas.0504823102","volume":"102","author":"H Drakesmith","year":"2005","unstructured":"Drakesmith H, Chen N, Ledemann H, Screaton G, Townsend A, Xu X (2005) HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. Proc Natl Acad Sci U S A 102(31):11017\u201311022","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"9928_CR29","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1046\/j.1360-0443.1999.9468135.x","volume":"94","author":"J Dunn","year":"1999","unstructured":"Dunn J, Laranjeira R (1999) Transitions in the route of cocaine administration--characteristics, direction and associated variables. Addiction 94(6):813\u2013824","journal-title":"Addiction"},{"issue":"2","key":"9928_CR30","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2016.271","volume":"7","author":"K Ersche","year":"2017","unstructured":"Ersche K, Acosta-Cabronero J, Jones P, Ziauddeen H, van Swekm R, Laarakkers C et al (2017) Disrupted iron regulation in the brain and periphery in cocaine addiction. Transl Psychiatry 7(2):e1040","journal-title":"Transl Psychiatry"},{"issue":"3","key":"9928_CR31","first-page":"1345","volume":"279","author":"S Evans","year":"1996","unstructured":"Evans S, Cone E, Henningfield J (1996) Arterial and venous cocaine plasma concentrations in humans: relationship to route of administration, cardiovascular effects and subjective effects. J Pharmacol Exp Ther 279(3):1345\u20131356","journal-title":"J Pharmacol Exp Ther"},{"key":"9928_CR32","doi-asserted-by":"publisher","unstructured":"Farhadian S, Mehta S, Zografou C, Robertson K, Price RP, Chiarella J, Hafler D (2018) Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV. JCI Insight 3(18):e121718. https:\/\/doi.org\/https:\/\/doi.org\/10.1172\/jci.insight.121718","DOI":"10.1172\/jci.insight.121718"},{"issue":"4","key":"9928_CR33","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.neuroscience.2009.01.024","volume":"159","author":"M Ferris","year":"2009","unstructured":"Ferris M, Frederick-Duus D, Fadel J, Mactutus C, Booze R (2009) The human immunodeficiency virus-1-associated protein, Tat1-86, impairs dopamine transporters and interacts with cocaine to reduce nerver terminal function: a no-net-flux microdialysis study. Neuroscience 159(4):1292\u20131299","journal-title":"Neuroscience"},{"issue":"5","key":"9928_CR34","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.neubiorev.2008.01.004","volume":"32","author":"M Ferris","year":"2008","unstructured":"Ferris M, Mactutus C, Booze R (2008) Neurotoxic profiles of HIV, psychostimulant drugs of abuse, and their concerted effect on the brain: current status of dopamine system vulnerability in NeuroAIDS. Neurosci Biobehav Rev 32(5):883\u2013909","journal-title":"Neurosci Biobehav Rev"},{"issue":"22","key":"9928_CR35","doi-asserted-by":"crossref","first-page":"9319","DOI":"10.1523\/JNEUROSCI.3278-12.2013","volume":"33","author":"KD Fischer","year":"2013","unstructured":"Fischer KD, Houston ACW, Rebec GV (2013) Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior. J Neurosci 33(22):9319\u20139327","journal-title":"J Neurosci"},{"issue":"1","key":"9928_CR36","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2174\/1570162X13666150121110731","volume":"13","author":"S Fitting","year":"2015","unstructured":"Fitting S, Booze R, Mactutus C (2015) HIV-1 proteins, tat and gp120, target the developing dopamine system. Curr HIV Res 13(1):21\u201342","journal-title":"Curr HIV Res"},{"issue":"5","key":"9928_CR37","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.biopsych.2012.09.026","volume":"73","author":"S Fitting","year":"2013","unstructured":"Fitting S, Ignatowska-Jankowska B, Bull C, Skoff R, Lichtman A, Wise L et al (2013) Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 tat transgenic mice. Biol Psychiatry 73(5):443\u2013453","journal-title":"Biol Psychiatry"},{"issue":"2","key":"9928_CR38","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/hup.1251","volume":"27","author":"H Fox","year":"2012","unstructured":"Fox H, D\u2019Sa C, Kimmerling A, Siedlarz K, Tuit K, Stowe R, Sinha R (2012) Immune system inflammation in cocaine dependent individuals: implications for medications development. Hum Psychopharmacol 27(2):156\u2013166","journal-title":"Hum Psychopharmacol"},{"issue":"2","key":"9928_CR39","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/glia.10155","volume":"40","author":"G Garden","year":"2002","unstructured":"Garden G (2002) Microglia in human immunodeficiency virus-associated neurodegeneration. Glia 40(2):240\u2013251","journal-title":"Glia"},{"issue":"1","key":"9928_CR40","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/01.aids.0000432467.54003.f7","volume":"28","author":"L Garvey","year":"2014","unstructured":"Garvey L, Pavese N, Politis M, Ramlackhansingh A, Brooks D, Taylor-Robinson S, Winston A (2014) Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART. AIDS 28(1):67\u201372","journal-title":"AIDS"},{"issue":"1","key":"9928_CR41","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.physbeh.2011.11.004","volume":"106","author":"O George","year":"2012","unstructured":"George O, Le Moal M, Koob G (2012) Allostasis and addiction: role of the dopamine and corticotrophin-releasing factor systems. Physiol Behav 106(1):58\u201364","journal-title":"Physiol Behav"},{"issue":"2","key":"9928_CR42","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s11065-009-9095-0","volume":"19","author":"A Gorman","year":"2009","unstructured":"Gorman A, Foley J, Ettenhofer M, Hinkin C, van Gorp W (2009) Functional consequences of HIV-associated neuropsychological impairment. Neuropsychol Rev 19(2):186\u2013203","journal-title":"Neuropsychol Rev"},{"issue":"7","key":"9928_CR43","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1080\/15548627.2015.1052205","volume":"11","author":"M Guo","year":"2015","unstructured":"Guo M, Liao K, Periyasamy P, Yang L, Cai Y, Callen S, Buch S (2015) Cocaine-mediated microglial activation involves the ER stress-autophagy axis. Autophagy 11(7):995\u20131009","journal-title":"Autophagy"},{"issue":"4","key":"9928_CR44","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.pbb.2008.05.020","volume":"90","author":"SB Harrod","year":"2008","unstructured":"Harrod SB, Mactutus CF, Fitting S, Hasselrot U, Booze RM (2008) Intra-accumbal Tat1-72 alters acute and sensitized responses to cocaine. Pharmacol Biochem Behav 90(4):723\u2013729","journal-title":"Pharmacol Biochem Behav"},{"issue":"23","key":"9928_CR45","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1212\/WNL.0b013e318200d727","volume":"75","author":"R Heaton","year":"2010","unstructured":"Heaton R, Clifford D, Franklin DJ, Woods S, Ake C, Vaida F et al (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER study. Neurology 75(23):2087\u20132096","journal-title":"Neurology"},{"issue":"4","key":"9928_CR46","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1901\/jeab.1966.9-421","volume":"9","author":"RJ Herrnstein","year":"1966","unstructured":"Herrnstein RJ, Hineline PN (1966) Negative reinforcement as shock-frequency reduction. J Exp Anal Behav 9(4):421\u2013430","journal-title":"J Exp Anal Behav"},{"issue":"3","key":"9928_CR47","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/hipo.22826","volume":"28","author":"L Hitchcock","year":"2018","unstructured":"Hitchcock L, Lattal K (2018) Involvement of the dorsal hippocampus in expression and extinction of cocaine-induced conditioned place preference. Hippocampus 28(3):226\u2013238","journal-title":"Hippocampus"},{"issue":"3","key":"9928_CR48","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1176\/jnp.2010.22.3.313","volume":"22","author":"J Hoare","year":"2010","unstructured":"Hoare J, Fouche J, Spottiswoode B, Joska J, Schoeman R, Stein D, Carey P (2010) White matter correlates of apathy in HIV-positive subjects: a diffusion tensor imaging study. J Neuropsychiatry Clin Neurosci 22(3):313\u2013320","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"9928_CR49","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.bbi.2017.10.017","volume":"68","author":"R Holland","year":"2018","unstructured":"Holland R, McIntosh AL, Finucane OM, Mela V, Rubio-Araiz A, Timmons G et al (2018) Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP\/PS1 mice. Brain Behav Immun 68:183\u2013196","journal-title":"Brain Behav Immun"},{"key":"9928_CR50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbi.2014.10.008","volume":"45","author":"S Hong","year":"2015","unstructured":"Hong S, Banks W (2015) Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications. Brain Behav Immun 45:1\u201312","journal-title":"Brain Behav Immun"},{"issue":"3","key":"9928_CR51","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1017\/S1355617715000156","volume":"21","author":"J Ipser","year":"2015","unstructured":"Ipser J, Brown G, Bischoff-Grethe A, Connolly C, Ellis R, Heaton R et al (2015) HIV infection is associated with attenuated Frontostriatal intrinsic connectivity: a preliminary study. J Int Neuropsychol Soc 21(3):203\u2013213","journal-title":"J Int Neuropsychol Soc"},{"issue":"11","key":"9928_CR52","doi-asserted-by":"crossref","first-page":"e0188404","DOI":"10.1371\/journal.pone.0188404","volume":"12","author":"M Javadi-Paydar","year":"2017","unstructured":"Javadi-Paydar M, Roscoe RJ, Denton A, Mactutus C, Booze R (2017) HIV-1 and cocaine disrupt dopamine reuptake and medium spiny neurons in female rat striatum. PLoS One 12(11):e0188404","journal-title":"PLoS One"},{"issue":"8","key":"9928_CR53","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1080\/13803395.2014.950636","volume":"36","author":"R Kamat","year":"2014","unstructured":"Kamat R, Brown G, Bolden K, Fennema-Notestein C, Archibald S, Marcotte T, Letendre SL, Ellis RJ, Woods SP, Grant I, Heaton RK, TMARC Group (2014) Apathy is associated with white matter abnormalities in anterior, medial brain regions in persons with HIV infection. J Clin Exp Neuropsychol 36(8):854\u2013866","journal-title":"J Clin Exp Neuropsychol"},{"issue":"7","key":"9928_CR54","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1080\/13548506.2015.1131998","volume":"21","author":"R Kamat","year":"2016","unstructured":"Kamat R, Woods S, Cameron M, Iudicello J, The HIV Neurobehavioral Research Program Group (2016) Apathy is associated with lower mental and physical quality of life in persons infected with HIV. Psychol Health Med 21(7):890\u2013901","journal-title":"Psychol Health Med"},{"issue":"5","key":"9928_CR55","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/arclin\/acs055","volume":"27","author":"R Kamat","year":"2012","unstructured":"Kamat R, Woods SP, Marcotte TD, Ellis RJ, Grant I (2012) Implications of apathy for everyday functioning outcomes in persons living with HIV infection. Arch Clin Neuropsych 27(5):520\u2013531","journal-title":"Arch Clin Neuropsych"},{"key":"9928_CR56","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pbb.2019.01.007","volume":"179","author":"M Kohno","year":"2019","unstructured":"Kohno M, Link J, Dennis L, McCready H, Huckans M, Hoffman W, Loftis J (2019) Neuroinflammation in addiction: a review of neuroimaging studies and potential immunotherapies. Pharmacol Biochem Behav 179:34\u201342","journal-title":"Pharmacol Biochem Behav"},{"key":"9928_CR57","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.neuropharm.2008.07.043","volume":"56","author":"G Koob","year":"2009","unstructured":"Koob G (2009) Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 56:1873\u20137064","journal-title":"Neuropharmacology"},{"key":"9928_CR58","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.psych.59.103006.093548","volume":"59","author":"G Koob","year":"2008","unstructured":"Koob G, Le Moal M (2008) Addiction and the brain antireward system. Annu Rev Psychol 59:29\u201353","journal-title":"Annu Rev Psychol"},{"issue":"2","key":"9928_CR59","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0893-133X(00)00195-0","volume":"24","author":"G Koob","year":"2001","unstructured":"Koob G, Le Moal M (2001) Drug addiction, Dysregulation of reward, and Allostasis. Neuropsychopharmacology 24(2):97\u2013129","journal-title":"Neuropsychopharmacology"},{"key":"9928_CR60","first-page":"2473","volume":"38","author":"C Kornetsky","year":"1979","unstructured":"Kornetsky C, Esposito RU (1979) Euphorigenic drugs: effects on the reward pathways of the brain. Fed Proc 38:2473\u20132476","journal-title":"Fed Proc"},{"issue":"1","key":"9928_CR61","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0740-5472(93)90100-G","volume":"10","author":"TA Kosten","year":"1993","unstructured":"Kosten TA, Gawin FH, Kosten TR, Rounsaville BJ (1993) Gender differences in cocaine use and treatment response. J Subst Abus Treat 10(1):63\u201366","journal-title":"J Subst Abus Treat"},{"issue":"3","key":"9928_CR62","first-page":"257","volume":"15","author":"A Kumar","year":"2009","unstructured":"Kumar A, Fernandez J, Singer E, Commins D, Waldrop-Valverde D, Ownby R, Kumar M (2009) Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains. J Neuro-Oncol 15(3):257\u2013274","journal-title":"J Neuro-Oncol"},{"issue":"1","key":"9928_CR63","first-page":"26","volume":"17","author":"A Kumar","year":"2011","unstructured":"Kumar A, Ownby R, Waldrop-Valverde D, Fernandez B, Kumar M (2011) Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance. J Neuro-Oncol 17(1):26\u201340","journal-title":"J Neuro-Oncol"},{"issue":"3","key":"9928_CR64","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1176\/jnp.10.3.314","volume":"10","author":"M Levy","year":"1998","unstructured":"Levy M, Cummings J, Fairbanks L, Masterman D, Miller B, Craig A et al (1998) Apathy is not depression. J Neuropsychiatry Clin Neurosci 10(3):314\u2013319","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"7","key":"9928_CR65","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1093\/cercor\/bhj043","volume":"16","author":"R Levy","year":"2006","unstructured":"Levy R, Dubois B (2006) Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex 16(7):916\u2013928","journal-title":"Cereb Cortex"},{"issue":"3","key":"9928_CR66","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1037\/1064-1297.7.3.198","volume":"7","author":"WJ Lynch","year":"1999","unstructured":"Lynch WJ, Carroll ME (1999) Regulation of intravenously self-administered nicotine in rats. Exp Clin Psychopharm 7(3):198\u2013207","journal-title":"Exp Clin Psychopharm"},{"issue":"1","key":"9928_CR67","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030241","volume":"7","author":"N Marie","year":"2012","unstructured":"Marie N, Canestrelli C, Noble F (2012) Transfer of neuroplasticity from nucleus accumbens core to shell is required for cocaine reward. PLoS One 7(1):e30241","journal-title":"PLoS One"},{"issue":"8","key":"9928_CR68","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1523\/JNEUROSCI.23-08-03531.2003","volume":"23","author":"K McFarland","year":"2003","unstructured":"McFarland K, Lapish C, Kalivas P (2003) Prefrontal glutamate release into the Core of the nucleus Accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 23(8):3531\u20133537","journal-title":"J Neurosci"},{"key":"9928_CR69","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.neubiorev.2015.04.008","volume":"55","author":"S McIntosh","year":"2015","unstructured":"McIntosh S, Sexton T, Pattison L, Childers S, Hemby S (2015) Neuropathological sequelae of human immunodeficiency virus and apathy: a review of neuropsychological and neuroimaging studies. Neurosci Biobehav Rev 55:147\u2013164","journal-title":"Neurosci Biobehav Rev"},{"key":"9928_CR70","doi-asserted-by":"crossref","first-page":"32831","DOI":"10.1038\/srep32831","volume":"6","author":"KA McLaurin","year":"2016","unstructured":"McLaurin KA, Booze RM, Mactutus CF (2016) Progression of temporal processing deficits in the HIV-1 transgenic rat. Sci Rep 6:32831","journal-title":"Sci Rep"},{"key":"9928_CR71","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3389\/fnbeh.2018.00285","volume":"12","author":"K McLaurin","year":"2018","unstructured":"McLaurin K, Cook A, Li H, League A, Mactutus C, Booze R (2018) Synaptic connectivity in medium spiny neurons of the nucleus Accumbens: a sex-dependent mechanism underlying apathy in the HIV-1 transgenic rat. Front Behav Neurosci 12:285","journal-title":"Front Behav Neurosci"},{"issue":"1","key":"9928_CR72","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/s41598-018-36822-1","volume":"9","author":"KA McLaurin","year":"2019","unstructured":"McLaurin KA, Li H, Booze RM, Mactutus CF (2019) Disruption of timing: NeuroHIV progression in the post-cART era. Sci Rep 9(1):827","journal-title":"Sci Rep"},{"issue":"2","key":"9928_CR73","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s10865-010-9293-5","volume":"34","author":"CS Meade","year":"2011","unstructured":"Meade CS, Conn NA, Skalski LM, Safren SA (2011) Neurocognitive impairment and medication adherence in HIV patients with and without cocaine dependence. J Behav Med 34(2):128\u2013138","journal-title":"J Behav Med"},{"issue":"4","key":"9928_CR74","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF00686974","volume":"76","author":"J Michaels","year":"1988","unstructured":"Michaels J, Price R, Rosenblum M (1988) Microglia in the giant cell encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion. Acta Neuropathol 76(4):373\u2013379","journal-title":"Acta Neuropathol"},{"issue":"3","key":"9928_CR75","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s11481-012-9369-9","volume":"7","author":"NM Midde","year":"2012","unstructured":"Midde NM, Gomez AM, Zhu J (2012) HIV-1 tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes. J NeuroImmune Pharmacol 7(3):629\u2013639","journal-title":"J NeuroImmune Pharmacol"},{"key":"9928_CR76","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/s41586-019-1235-y","volume":"570","author":"A Mohebi","year":"2019","unstructured":"Mohebi A, Pettibone JR, Hamis AA, Wong JT, Vinson LT, Patriarchi T et al (2019) Dissociable dopamine dynamics for learning and motivation. Nature 570:65\u201370","journal-title":"Nature"},{"key":"9928_CR77","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.drugalcdep.2015.11.024","volume":"158","author":"F Moreira","year":"2016","unstructured":"Moreira F, Medeiros J, Lhullier A, Souza L, Jansen K, Portela L et al (2016) Cocaine abuse and effects in the serum levels of cytokines IL-6 and IL-10. Drug Alcohol Depend 158:181\u2013185","journal-title":"Drug Alcohol Depend"},{"issue":"1","key":"9928_CR78","first-page":"66","volume":"7","author":"A Nath","year":"2001","unstructured":"Nath A, Maragos W, Avison M, Schmitt F, Berger J (2001) Acceleration of HIV dementia with methamphetamine and cocaine. J Neuro-Oncol 7(1):66\u201371","journal-title":"J Neuro-Oncol"},{"key":"9928_CR79","doi-asserted-by":"crossref","unstructured":"Navia BA, Jordan BD, Price RW (1986) The AIDS Dementia complex .1. Clinical Features. Ann Neurol 19(6):517\u2013524","DOI":"10.1002\/ana.410190602"},{"issue":"1","key":"9928_CR80","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0301-0082(02)00011-4","volume":"67","author":"A Nieoullon","year":"2002","unstructured":"Nieoullon A (2002) Dopamine and the regulation of cognition and attention. Prog Neurobiol 67(1):53\u201383","journal-title":"Prog Neurobiol"},{"issue":"6","key":"9928_CR81","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1007\/s00415-009-5052-3","volume":"256","author":"M Obermann","year":"2009","unstructured":"Obermann M, Kuper M, Kastrup O, Yaldizli O, Esser S, Theirmann J, German Competence Network HIV\/AIDS (2009) Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV. J Neurol 256(6):948\u2013953","journal-title":"J Neurol"},{"key":"9928_CR82","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1037\/h0058775","volume":"47","author":"J Olds","year":"1954","unstructured":"Olds J, Milner P (1954) Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol 47:419\u2013427","journal-title":"J Comp Physiol Psychol"},{"issue":"5","key":"9928_CR83","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/npp.2008.186","volume":"24","author":"E Oleson","year":"2009","unstructured":"Oleson E, Talluri S, Childers S, Smith J, Roberts D, Bonin K, Budygin E (2009) Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology 24(5):1174\u20131184","journal-title":"Neuropsychopharmacology"},{"key":"9928_CR84","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ebiom.2016.02.012","volume":"6","author":"CS Palmer","year":"2016","unstructured":"Palmer CS, Cherry CL, Sada-Ovalle I, Singh A, Crowe SM (2016) Glucose metabolism in T cells and monocytes: new perspective in HIV pathogenesis. EBioMedicine 6:31\u201341","journal-title":"EBioMedicine"},{"issue":"1\u20133","key":"9928_CR85","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ejphar.2007.02.035","volume":"563","author":"J Parlaman","year":"2007","unstructured":"Parlaman J, Thompson B, Levitt P, Stanwood G (2007) Pharmacokinetic profile of cocaine following intravenous administration in the female rabbit. Eur J Pharmacol 563(1\u20133):124\u2013129","journal-title":"Eur J Pharmacol"},{"issue":"5","key":"9928_CR86","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1523\/JNEUROSCI.2777-14.2015","volume":"35","author":"MA Parvaz","year":"2015","unstructured":"Parvaz MA, Konova AB, Proudfit GH, Dunning JP, Malaker P, Moeller SJ, Maloney T, Alia-Klein N, Goldstein RZ (2015) Impaired neural response to negative prediction errors in cocaine addiction. J Neurosci 35(5):1872\u20131879","journal-title":"J Neurosci"},{"issue":"2","key":"9928_CR87","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1176\/jnp.17.2.167","volume":"17","author":"R Paul","year":"2005","unstructured":"Paul R, Brickman AN, Hinkin C, Malloy P, Jefferson A, Cohen R et al (2005) Apathy is associated with volume of the nucleus accumbens in patients infected with HIV. J Neuropsychiatry Clin Neurosci 17(2):167\u2013171","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"4","key":"9928_CR88","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1007\/s12035-017-0584-5","volume":"55","author":"P Periyasamy","year":"2018","unstructured":"Periyasamy P, Liao K, Kook Y, Niu F, Callen S, Guo M, Buch S (2018) Cocaine-mediated Downregulation of miR-124 activates microglia by targeting KLF4 and TLR4 signaling. Mol Neurobiol 55(4):3196\u20133210","journal-title":"Mol Neurobiol"},{"issue":"6932","key":"9928_CR89","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/nature01476","volume":"422","author":"P Phillips","year":"2003","unstructured":"Phillips P, Stuber G, Heien M, Wightman R, Carelli R (2003) Subsecond dopamine release promotes cocaine seeking. Nature 422(6932):614\u2013618","journal-title":"Nature"},{"issue":"6","key":"9928_CR90","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1097\/QAD.0000000000000151","volume":"28","author":"S Plessis","year":"2014","unstructured":"Plessis S, Vink M, Joska J, Koutsilieri E, Stein D, Emsley R (2014) HIV infection and the fronto- striatal system: a systematic review and meta- analysis of fMRI studies. AIDS 28(6):803\u2013811","journal-title":"AIDS"},{"issue":"2\u20133","key":"9928_CR91","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/BF02244931","volume":"112","author":"L Porrino","year":"1993","unstructured":"Porrino L (1993) Functional consequences of acute cocaine treatment depend on route of administration. Psychopharmacology 112(2\u20133):343\u2013351","journal-title":"Psychopharmacology"},{"issue":"1","key":"9928_CR92","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s12035-011-8195-z","volume":"44","author":"V Purohit","year":"2011","unstructured":"Purohit V, Rapaka R, Shurtleff D (2011) Drugs of abuse, dopamine, and HIV-associated neurocognitive disorders\/HIV-associated dementia. Mol Neurobiol 44(1):102\u2013110","journal-title":"Mol Neurobiol"},{"issue":"2","key":"9928_CR93","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1037\/0003-066X.42.2.119","volume":"42","author":"R Rescorla","year":"1987","unstructured":"Rescorla R (1987) A Pavlovian analysis of goal-directed behavior. Am Psychol 42(2):119\u2013129","journal-title":"Am Psychol"},{"issue":"1","key":"9928_CR94","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1355617704101021","volume":"10","author":"J Rippeth","year":"2004","unstructured":"Rippeth J, Heaton R, Carey C, Marcotte T, Moore D, Gonzalez R, The HNRC Group (2004) Methamphetamine dependence increases risk of neuropsychological impairment in HIV infected persons. J Int Neuropsychol Soc 10(1):1\u201314","journal-title":"J Int Neuropsychol Soc"},{"issue":"3","key":"9928_CR95","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/BF00451696","volume":"98","author":"DCS Roberts","year":"1989","unstructured":"Roberts DCS, Bennett SAL, Vickers GJ (1989) The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats. Psychopharmacol 98(3):408\u2013411","journal-title":"Psychopharmacol"},{"issue":"1507","key":"9928_CR96","doi-asserted-by":"crossref","first-page":"3137","DOI":"10.1098\/rstb.2008.0093","volume":"363","author":"T Robinson","year":"2008","unstructured":"Robinson T, Berridge K (2008) The incentive sensitization theory of addiction: some current issues. Philos Trans R Soc Lond Ser B Biol Sci 363(1507):3137\u20133146","journal-title":"Philos Trans R Soc Lond Ser B Biol Sci"},{"key":"9928_CR97","volume-title":"Sign tracking and drug addiction","author":"T Robinson","year":"2018","unstructured":"Robinson T, Carr C, Kawa A (2018) The propensity to attribute incentive salience to drug cues and poor cognitive control combine to render sign-trackers susceptible to addiction. In: Morrow J, Tomie A (eds) Sign tracking and drug addiction. Michigan Publishing, Ann Arbor"},{"key":"9928_CR98","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1007\/s11481-014-9555-z","volume":"9","author":"R Roscoe","year":"2014","unstructured":"Roscoe R, Mactutus C, Booze R (2014) HIV-1 transgenic female rat: Synaptodendritic alterations of medium spiny neurons in the nucleus Accumbens. J NeuroImmune Pharmacol 9:642\u2013653","journal-title":"J NeuroImmune Pharmacol"},{"issue":"2","key":"9928_CR99","doi-asserted-by":"crossref","first-page":"e0147182","DOI":"10.1371\/journal.pone.0147182","volume":"11","author":"W Royal III","year":"2016","unstructured":"Royal W III, Cherner M, Burdo TH, Umlauf A, Letendre SL, Jumare J et al (2016) Associations between cognition, gender and monocyte activation among HIV infected individuals in Nigeria. PLoS ONE 11(2):e0147182","journal-title":"PLoS ONE"},{"issue":"10","key":"9928_CR100","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/s11920-019-1089-x","volume":"21","author":"LH Rubin","year":"2019","unstructured":"Rubin LH, Neigh GN, Sundermann EE, Xu YX, Scully EP, Maki PM (2019) Sex differences in neurocognitive function in adults with HIV: patterns, predictors, and mechanisms. Curr Psychiatry Rep 21(10):94","journal-title":"Curr Psychiatry Rep"},{"issue":"1","key":"9928_CR101","doi-asserted-by":"crossref","first-page":"23","DOI":"10.31887\/DCNS.2016.18.1\/wschultz","volume":"18","author":"W Schultz","year":"2016","unstructured":"Schultz W (2016) Dopamine reward prediction error coding. Dialogues Clin Neurosci 18(1):23\u201332","journal-title":"Dialogues Clin Neurosci"},{"issue":"5306","key":"9928_CR102","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1126\/science.275.5306.1593","volume":"275","author":"W Schultz","year":"1997","unstructured":"Schultz W, Dayan P, Montague P (1997) A neural substrate of prediction and reward. Science 275(5306):1593\u20131599","journal-title":"Science"},{"issue":"2","key":"9928_CR103","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/cne.903200202","volume":"320","author":"S Sesack","year":"1992","unstructured":"Sesack S, Pickel V (1992) Prefrontal cortical Efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus Accumbens Septi and on dopamine neurons in the ventral tegmental area. J Comp Neurol 320(2):145\u2013160","journal-title":"J Comp Neurol"},{"issue":"9","key":"9928_CR104","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1080\/13803395.2013.838941","volume":"35","author":"M Shapiro","year":"2013","unstructured":"Shapiro M, Mahoney J, Zingman B, Pogge D, Verghese J (2013) Apathy correlates with cognitive performance, functional disability, and HIV RNA plasma levels in HIV-positive individuals. J Clin Exp Neuropsychol 35(9):934\u2013945","journal-title":"J Clin Exp Neuropsychol"},{"issue":"2","key":"9928_CR105","first-page":"140","volume":"12","author":"J Silvers","year":"2006","unstructured":"Silvers J, Aksenov M, Aksenova M, Beckley J, Olton P, Mactutus C, Booze R (2006) Dopaminergic marker proteins in the substantia nigra of human immunodeficiency virus type 1-infected brains. J Neuro-Oncol 12(2):140\u2013145","journal-title":"J Neuro-Oncol"},{"key":"9928_CR106","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.nucmedbio.2017.08.004","volume":"55","author":"S Sinharay","year":"2017","unstructured":"Sinharay S, Lee D, Shah S, Muthusamy S, Papadakis GZ, Zhang X, Maric D, Reid WC, Hammoud DA (2017) Cross-sectional and longitudinal small animal PET shows pre and post-synaptic striatal dopaminergic deficits in an animal model of HIV. Nucl Med Biol 55:27\u201333","journal-title":"Nucl Med Biol"},{"key":"9928_CR107","volume-title":"The behavior of organisms: an experimental analysis","author":"B Skinner","year":"1938","unstructured":"Skinner B (1938) The behavior of organisms: an experimental analysis. Appleton-Century, New York"},{"key":"9928_CR108","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1037\/h0036128","volume":"81","author":"RL Solomon","year":"1974","unstructured":"Solomon RL, Corbit JD (1974) An opponent-process theory of motivation: 1. Temporal dynamics of affect. Psychol Rev 81:119\u2013145","journal-title":"Psychol Rev"},{"issue":"2","key":"9928_CR109","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.neuron.2018.11.025","volume":"101","author":"YK Takahashi","year":"2019","unstructured":"Takahashi YK, Stalnaker TA, Marrero-Garcia Y, Rada RM, Schenbaum G (2019) Expectancy-related changes in dopaminergic error signals are impaired by cocaine self-administration. Neuron 101(2):294\u2013306","journal-title":"Neuron"},{"key":"9928_CR110","doi-asserted-by":"publisher","unstructured":"Tang V, Lang D, Giesbrecht C, Panenka W, Willi T, Procyshyn R, et al (2015) White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection. BMC Res Notes 8(515). https:\/\/doi.org\/https:\/\/doi.org\/10.1186\/s13104-015-1501-5","DOI":"10.1186\/s13104-015-1501-5"},{"issue":"6","key":"9928_CR111","doi-asserted-by":"crossref","DOI":"10.4161\/cib.27670","volume":"6","author":"M Tremblay","year":"2013","unstructured":"Tremblay M, Marker D, Puccini J, Muly E, Lu S, Gelbard H (2013) Ultrastructure of microglia-synapse interactions in the HIV-1 tat-injected murine central nervous system. Commun Integr Biol 6(6):e27670","journal-title":"Commun Integr Biol"},{"issue":"3","key":"9928_CR112","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/scientificamerican0382-128","volume":"246","author":"C Van Dyke","year":"1982","unstructured":"Van Dyke C, Byck R (1982) Cocaine. Sci Am 246(3):128\u2013140","journal-title":"Sci Am"},{"issue":"1","key":"9928_CR113","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1176\/jnp.17.1.7","volume":"17","author":"R van Reekum","year":"2005","unstructured":"van Reekum R, Stuss D, Ostrander L (2005) Apathy: why care? J Neuropsychiatry Clin Neurosci 17(1):7\u201319","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"6","key":"9928_CR114","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1176\/ajp.147.6.719","volume":"147","author":"N Volkow","year":"1990","unstructured":"Volkow N, Fowler J, Wolf A, Schlyer D, Shiue C, Alpert R, Dewey SL, Logan J, Bendriem B, Christman D (1990) Effects on chronic cocaine abuse on postsynaptic dopamine receptors. Am J Psychiatry 147(6):719\u2013724","journal-title":"Am J Psychiatry"},{"issue":"6627","key":"9928_CR115","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/386830a0","volume":"386","author":"N Volkow","year":"1997","unstructured":"Volkow N, Wang G, Fowler J, Logan J, Gatley S, Hitzemann R et al (1997) Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 386(6627):830\u2013833","journal-title":"Nature"},{"issue":"11","key":"9928_CR116","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1093\/brain\/awh269","volume":"127","author":"G Wang","year":"2004","unstructured":"Wang G, Chang L, Volkow N, Telang F, Logan J, Ernst T, Fowler J (2004) Decreased brain dopaminergic transporters in HIV-associated dementia patients. Brain 127(11):2452\u20132458","journal-title":"Brain"},{"issue":"5","key":"9928_CR117","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/nn.3694","volume":"17","author":"I Willuhn","year":"2014","unstructured":"Willuhn I, Burgeno L, Groblewski P, Phillips P (2014) Excessive cocaine use results from decreased phasic dopamine signaling in the striatum. Nat Neurosci 17(5):704\u2013709","journal-title":"Nat Neurosci"},{"issue":"2","key":"9928_CR118","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/npp.2013.261","volume":"39","author":"R Wise","year":"2014","unstructured":"Wise R, Koob G (2014) The development and maintenance of drug addiction. Neuropsychopharmacology 39(2):254\u2013262","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"9928_CR119","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/npp.2017.228","volume":"43","author":"R Wise","year":"2018","unstructured":"Wise R, McDevitt R (2018) Drive and reinforcement circuitry in the brain: origins, neurotransmitters, and projection fields. Neuropsychopharmacology 43(4):680\u2013689","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"9928_CR120","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.neuron.2017.12.022","volume":"97","author":"H Yang","year":"2018","unstructured":"Yang H, de Jong J, Tak Y, Peck J, Bateup H, Lammel S (2018) Nucleus Accumbens subnuclei regulate motivated behavior via direct inhibition and Disinhibition of VTA dopamine subpopulations. Neuron 97(2):434\u2013449","journal-title":"Neuron"},{"issue":"3","key":"9928_CR121","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1124\/jpet.108.150144","volume":"329","author":"J Zhu","year":"2009","unstructured":"Zhu J, Mactutus C, Wallace D, Booze R (2009) HIV-1 tat protein-induced rapid and reversible decrease in [H-3]dopamine uptake: dissociation of [H-3]dopamine uptake and [H-3]2 beta-Carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal Synaptosomes. J Pharmacol Exp Ther 329(3):1071\u20131083","journal-title":"J Pharmacol Exp Ther"}],"updated-by":[{"DOI":"10.1007\/s11481-020-09942-7","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T00:00:00Z","timestamp":1595894400000}}],"container-title":["Journal of Neuroimmune Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11481-020-09928-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11481-020-09928-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11481-020-09928-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T23:48:36Z","timestamp":1623455316000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11481-020-09928-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,12]]},"references-count":121,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["9928"],"URL":"https:\/\/doi.org\/10.1007\/s11481-020-09928-5","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s11481-020-09942-7","asserted-by":"object"}]},"ISSN":["1557-1890","1557-1904"],"issn-type":[{"value":"1557-1890","type":"print"},{"value":"1557-1904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,12]]},"assertion":[{"value":"8 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2020","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Corrected sentence in <Emphasis Type=\"Bold\">Interactions between the Effects of Drug Use and HIV-1 Infection Leads to Accelerated Disease Progression:<\/Emphasis> \u201cWhite matter damage (Tang et al. 2015; Alakkas et al. 2019), mitochondrial dysfunction (Buch et al. 2011), and iron dysregulation (Drakesmith et al. 2005; Ersche et al. 2017) occur with cocaine use and have also been associated with HIV infection and HAND; these processes may therefore be promising targets for treatment development.\u201d","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest. Supported by NIH Grants HD043680, MH106392, DA013137, NS100624 and T32 GM081740.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}