{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:36:36Z","timestamp":1761395796844,"version":"3.37.3"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T00:00:00Z","timestamp":1594944000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T00:00:00Z","timestamp":1594944000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/3\/8\/322\/2016"],"award-info":[{"award-number":["5\/3\/8\/322\/2016"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s11517-020-02191-z","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T23:05:55Z","timestamp":1595027155000},"page":"2143-2159","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Label-free detection of thalassemia and other ROS impairing diseases"],"prefix":"10.1007","volume":"58","author":[{"given":"Ayan","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjoy Kumar","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3974-1394","authenticated-orcid":false,"given":"Anjan Kr","family":"Dasgupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,17]]},"reference":[{"key":"2191_CR1","volume-title":"Categorical data analysis, vol 482","author":"A Agresti","year":"2003","unstructured":"Agresti A (2003) Categorical data analysis, vol 482. Wiley, New York"},{"key":"2191_CR2","doi-asserted-by":"crossref","unstructured":"Badawy AAB (2017) Kynurenine pathway of tryptophan metabolism: regulatory and functional aspects. Int J Tryptophan Res. https:\/\/doi.org\/10:1178646917691938","DOI":"10.1177\/1178646917691938"},{"issue":"1","key":"2191_CR3","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/S0043-1354(01)00210-X","volume":"36","author":"A Baker","year":"2002","unstructured":"Baker A (2002) Fluorescence properties of some farm wastes: implications for water quality monitoring. Water Res 36(1):189\u2013195","journal-title":"Water Res"},{"key":"2191_CR4","doi-asserted-by":"crossref","unstructured":"Borisova E, Gisbrecht A, Genova-Hristova T, Troyanova P, Pavlova E, Penkov N, Bratchenko I, Zakharov V, Lihachova I, Kuzmina I et al (2019) Multispectral autoflourescence detection of skin neoplasia using steady-state techniques. In: 20th International conference and school on quantum electronics: laser physics and applications, vol 11047. International Society for Optics and Photonics, p 1104704","DOI":"10.1117\/12.2516337"},{"issue":"18","key":"2191_CR5","doi-asserted-by":"publisher","first-page":"3197","DOI":"10.1364\/AO.20.003197","volume":"20","author":"FE Hoge","year":"1981","unstructured":"Hoge FE, Swift RN (1981) Airborne simultaneous spectroscopic detection of laser-induced water raman backscatter and fluorescence from chlorophyll a and other naturally occurring pigments. Appl Optics 20(18):3197\u20133205","journal-title":"Appl Optics"},{"issue":"3","key":"2191_CR6","doi-asserted-by":"publisher","first-page":"3895","DOI":"10.18632\/oncotarget.13904","volume":"8","author":"AV Ivanov","year":"2017","unstructured":"Ivanov AV, Valuev-Elliston VT, Tyurina DA, Ivanova ON, Kochetkov SN, Bartosch B, Isaguliants MG (2017) Oxidative stress, a trigger of hepatitis c and b virus-induced liver carcinogenesis. Oncotarget 8(3):3895","journal-title":"Oncotarget"},{"issue":"4","key":"2191_CR7","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.1074\/jbc.M110.168286","volume":"286","author":"W Lin","year":"2011","unstructured":"Lin W, Wu G, Li S, Weinberg EM, Kumthip K, Peng LF, M\u00e9ndez-Navarro J, Chen W-C, Jilg N, Zhao H et al (2011) Hiv and hcv cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and nf\u03ba b. J Biol Chem 286(4):2665\u2013 2674","journal-title":"J Biol Chem"},{"key":"2191_CR8","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.ejphar.2017.10.048","volume":"818","author":"S\u00c1 Mej\u00eda","year":"2018","unstructured":"Mej\u00eda S\u00c1, Gutman LAB, Camarillo CO, Navarro RM, Becerra MCS, Santana LD, P\u00e9rez M C EH, Flores MD (2018) Nicotinamide prevents sweet beverage-induced hepatic steatosis in rats by regulating the g6pd, nadph\/nadp+ and gsh\/gssg ratios and reducing oxidative and inflammatory stress. Eur J Pharmacol 818:499\u2013507","journal-title":"Eur J Pharmacol"},{"issue":"6","key":"2191_CR9","doi-asserted-by":"publisher","first-page":"472","DOI":"10.3109\/03009741003742722","volume":"39","author":"C Modesto","year":"2010","unstructured":"Modesto C, Anton J, Rodriguez B, Bou R, Arnal C, Ros J, Tena X, Rodrigo C, Rotes I, Hermosilla E et al (2010) Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain). Scand J Rheumatol 39(6):472\u2013479","journal-title":"Scand J Rheumatol"},{"key":"2191_CR10","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.jlumin.2012.12.056","volume":"137","author":"ME Pacheco","year":"2013","unstructured":"Pacheco ME, Bruzzone L (2013) Synchronous fluorescence spectrometry: conformational investigation or inner filter effect?. J Lumin 137:138\u2013142","journal-title":"J Lumin"},{"issue":"3","key":"2191_CR11","doi-asserted-by":"publisher","first-page":"035701","DOI":"10.1088\/1612-202X\/aa9321","volume":"15","author":"SM Pershin","year":"2018","unstructured":"Pershin SM, Grishin MYa, Lednev VN, Garnov SV, Bukin VV, Chizhov PA, Khodasevich IA, Oshurko VB (2018) Quantification of distortion of the water oh-band using picosecond raman spectroscopy. Laser Phys Lett 15(3):035701","journal-title":"Laser Phys Lett"},{"key":"2191_CR12","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.cbi.2017.12.024","volume":"281","author":"A-R Phull","year":"2018","unstructured":"Phull A-R, Nasir B, ul Haq I, Kim SJ (2018) Oxidative stress, consequences and ros mediated cellular signaling in rheumatoid arthritis. Chemico-Biol Interact 281:121\u2013136","journal-title":"Chemico-Biol Interact"},{"issue":"4","key":"2191_CR13","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1159\/000207129","volume":"66","author":"P Pootrakul","year":"1981","unstructured":"Pootrakul P, Vongsmasa V, La-Ongpanich P, Wasi P (1981) Serum ferritin levels in thalassemias and the effect of splenectomy. Acta Haematol 66(4):244\u2013250","journal-title":"Acta Haematol"},{"issue":"16","key":"2191_CR14","doi-asserted-by":"publisher","first-page":"6228","DOI":"10.1039\/C3AY41736K","volume":"6","author":"SO Raja","year":"2014","unstructured":"Raja SO, Shaw J, Chattopadhyay A, Chatterjee S, Bhattacharya M, Dasgupta AK (2014) Synchronous fluorescence based one step optical method for assessing oxidative stress and its dependence on serum ferritin. Anal Methods 6(16):6228\u20136231","journal-title":"Anal Methods"},{"key":"2191_CR15","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.talanta.2016.06.037","volume":"159","author":"R Risoluti","year":"2016","unstructured":"Risoluti R, Materazzi S, Sorrentino F, Maffei L, Caprari P (2016) Thermogravimetric analysis coupled with chemometrics as a powerful predictive tool for \u00df-thalassemia screening. Talanta 159:425\u2013432","journal-title":"Talanta"},{"issue":"3","key":"2191_CR16","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1097\/MOH.0b013e32832990a4","volume":"16","author":"S Rivella","year":"2009","unstructured":"Rivella S (2009) Ineffective erythropoiesis and thalassemias. Curr Opin Hematol 16(3):187","journal-title":"Curr Opin Hematol"},{"issue":"1\u20132","key":"2191_CR17","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1046\/j.1472-4642.2001.00094.x","volume":"7","author":"MP Robertson","year":"2001","unstructured":"Robertson MP, Caithness N, Villet MH (2001) A pca-based modelling technique for predicting environmental suitability for organisms from presence records. Divers Distrib 7(1\u20132):15\u201327","journal-title":"Divers Distrib"},{"key":"2191_CR18","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.freeradbiomed.2013.05.019","volume":"63","author":"J Rybka","year":"2013","unstructured":"Rybka J, Kdziora-Kornatowska K, BanasLezanska P, Majsterek I, Carvalho LA, Cattaneo A, Anacker C, Kedziora J (2013) Interplay between the pro-oxidant and antioxidant systems and proinflammatory cytokine levels, in relation to iron metabolism and the erythron in depression. Free Radic Biol Med 63:187\u2013194","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"2191_CR19","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3390\/molecules23010191","volume":"23","author":"K Sas","year":"2018","unstructured":"Sas K, Szab\u00f3 E, V\u00e9csei L (2018) Mitochondria, oxidative stress and the kynurenine system, with a focus on ageing and neuroprotection. Molecules 23(1):191","journal-title":"Molecules"},{"issue":"5","key":"2191_CR20","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1111\/ejh.12936","volume":"99","author":"J Shaw","year":"2017","unstructured":"Shaw J, Chakraborty A, Nag A, Chattopadyay A, Dasgupta AK, Bhattacharyya M (2017) Intracellular iron overload leading to dna damage of lymphocytes and immune dysfunction in thalassemia major patients. Eur J Haematol 99(5):399\u2013408","journal-title":"Eur J Haematol"},{"key":"2191_CR21","doi-asserted-by":"crossref","unstructured":"Shaw J, Chakraborty A, Chatterjee S, Bhattacharyya M, Dasgupta AK (2018) Chelation therapy using static magnetic field. bioRxiv p 429597","DOI":"10.1101\/429597"},{"key":"2191_CR22","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139979573","volume-title":"Cause and correlation in biology: a user\u2019s guide to path analysis, structural equations and causal inference with R","author":"B Shipley","year":"2016","unstructured":"Shipley B (2016) Cause and correlation in biology: a user\u2019s guide to path analysis, structural equations and causal inference with R. Cambridge University Press, Cambridge"},{"issue":"20","key":"2191_CR23","doi-asserted-by":"publisher","first-page":"3940","DOI":"10.1093\/bioinformatics\/bti623","volume":"21","author":"T Sing","year":"2005","unstructured":"Sing T, Sander O, Beerenwinkel N, Lengauer T (2005) Rocr: visualizing classifier performance in r. Bioinformatics 21(20):3940\u20133941","journal-title":"Bioinformatics"},{"issue":"8","key":"2191_CR24","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1136\/jcp.30.8.782-c","volume":"30","author":"PA Trott","year":"1977","unstructured":"Trott PA (1977) International classification of diseases for oncology. J Clin Pathol 30(8):782","journal-title":"J Clin Pathol"},{"key":"2191_CR25","first-page":"CIN","volume":"13","author":"NK Venepalli","year":"2014","unstructured":"Venepalli NK, Shergill A, Dorestani P, Boyd AD (2014) Conducting retrospective ontological clinical trials in icd-9-cm in the age of icd-10-cm. Cancer Inform 13:CIN\u2013S14032","journal-title":"Cancer Inform"},{"issue":"1","key":"2191_CR26","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.tips.2011.09.001","volume":"33","author":"R Vlahos","year":"2012","unstructured":"Vlahos R, Stambas J, Selemidis S (2012) Suppressing production of reactive oxygen species (ros) for influenza a virus therapy. Trends Pharmacol Sci 33(1):3\u20138","journal-title":"Trends Pharmacol Sci"},{"issue":"4","key":"2191_CR27","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1093\/ejo\/cjx002","volume":"39","author":"HLL Wellens","year":"2017","unstructured":"Wellens HLL, BeGole EA, Kuijpers-Jagtman AM (2017) Roc surface assessment of the anb angle and wits appraisal\u2019?s diagnostic performance with a statistically derived \u2018gold standard\u2019: does normalizing measurements have any merit?. Eur J Orthod 39(4):358\u2013364","journal-title":"Eur J Orthod"}],"container-title":["Medical & Biological Engineering & Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-020-02191-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11517-020-02191-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-020-02191-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T23:27:54Z","timestamp":1626478074000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11517-020-02191-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,17]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["2191"],"URL":"https:\/\/doi.org\/10.1007\/s11517-020-02191-z","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"type":"print","value":"0140-0118"},{"type":"electronic","value":"1741-0444"}],"subject":[],"published":{"date-parts":[[2020,7,17]]},"assertion":[{"value":"26 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}