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The internal cohort was approved by the Research and New Technology Ethics Committee of Yijishan Hospital of Wannan Medical College (Ethics Approval No. 61 (2019)). The external cohort was approved by the Medical Ethics Committee of Wuhu Second People\u2019s Hospital (Ethics Approval No. 2024-KY-191). The requirement for informed consent was waived for both cohorts.","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}