{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T14:38:57Z","timestamp":1773671937185,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T00:00:00Z","timestamp":1386806400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiol med"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1007\/s11547-013-0326-3","type":"journal-article","created":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T10:21:42Z","timestamp":1386757302000},"page":"201-207","source":"Crossref","is-referenced-by-count":12,"title":["Head and neck intensity modulated radiotherapy parotid glands: time of re-planning"],"prefix":"10.1007","volume":"119","author":[{"given":"Alba","family":"Fiorentino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariella","family":"Cozzolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocchina","family":"Caivano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piernicola","family":"Pedicini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Oliviero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Costanza","family":"Chiumento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Fusco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,12,12]]},"reference":[{"key":"326_CR1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.radonc.2006.02.017","volume":"78","author":"K Saarilahti","year":"2006","unstructured":"Saarilahti K, Kouri M, Collan J et al (2006) Sparing of submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer. Radiother Oncol 78:270\u2013275","journal-title":"Radiother Oncol"},{"key":"326_CR2","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.ijrobp.2007.01.030","volume":"68","author":"JL Robar","year":"2007","unstructured":"Robar JL, Day A, Clancey J et al (2007) Spatial and dosimetric variability of organs at risk in head-and-neck intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 68:1121\u20131130","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR3","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1259\/bjr\/30678306","volume":"85","author":"A Fiorentino","year":"2012","unstructured":"Fiorentino A, Caivano R, Metallo V et al (2012) Parotid glands volumetric changes during intensity-modulated radiotherapy in head and neck cancer. Br J Radiol 85:1415\u20131419","journal-title":"Br J Radiol"},{"key":"326_CR4","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.ijrobp.2003.12.024","volume":"59","author":"JL Barker Jr","year":"2004","unstructured":"Barker JL Jr, Garden AS, Ang KK et al (2004) Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT\/linear accelerator system. Int J Radiat Oncol Biol Phys 59:960\u2013970","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR5","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.ijrobp.2008.04.013","volume":"71","author":"C Lee","year":"2008","unstructured":"Lee C, Langen KM, Lu W et al (2008) Assessment of parotid gland dose changes during head and neck cancer radiotherapy using daily megavoltage computed tomography and deformable image registration. Int J Radiat Oncol Biol Phys 71:1563\u20131571","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR6","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.ijrobp.2007.10.067","volume":"70","author":"C Han","year":"2008","unstructured":"Han C, Chen YJ, Liu A, Schultheiss TE, Wong JY (2008) Actual dose variation of parotid glands and spinal cord for nasopharyngeal cancer patients during radiotherapy. Int J Radiat Oncol Biol Phys 70:1256\u20131262","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR7","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijrobp.2005.07.957","volume":"64","author":"EK Hansen","year":"2006","unstructured":"Hansen EK, Bucci MK, Quivey JM et al (2006) Repeat CT imaging and replanning during the course of IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 64:355\u2013362","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR8","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3390\/curroncol13030010","volume":"13","author":"O Ballivy","year":"2006","unstructured":"Ballivy O, Parker W, Vuong T et al (2006) Impact of geometric uncertainties on the dose distribution during intensity-modulated radiotherapy (IMRT) of head and neck cancer: the need for planning target volume (PTV) and planning organ at risk volume (PRV). Curr Oncol 13:108\u2013115","journal-title":"Curr Oncol"},{"key":"326_CR9","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.ijrobp.2009.04.047","volume":"75","author":"Q Wu","year":"2009","unstructured":"Wu Q, Chi Y, Chen PY et al (2009) Adaptive replanning strategies accounting for shrinkage in head and neck IMRT. Int J Radiat Oncol Biol Phys 75:924\u2013932","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.radonc.2010.10.009","volume":"98","author":"L Zhao","year":"2011","unstructured":"Zhao L, Wan Q, Zhou Y et al (2011) The role of replanning in fractionated intensity modulated radiotherapy for nasopharyngeal carcinoma. Radiother Oncol 98:23\u201327","journal-title":"Radiother Oncol"},{"issue":"5","key":"326_CR11","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.ijrobp.2009.04.005","volume":"76","author":"SA Bhide","year":"2010","unstructured":"Bhide SA, Davies M, Burke K et al (2010) Weekly volume and dosimetric changes during chemoradiotherapy with intensity modulated radiation therapy for head and neck cancer: a prospective observational study. Int J Radiat Oncol Biol Phys 76(5):1360\u20131368","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR12","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/jjco\/hyi108","volume":"35","author":"Y Nishimura","year":"2005","unstructured":"Nishimura Y, Nakamatsu K, Shibata T et al (2005) Importance of the initial volume of parotid glands in xerostomia for patients with head and neck cancer treated with IMRT. Jpn J Clin Oncol 35:375\u2013379","journal-title":"Jpn J Clin Oncol"},{"key":"326_CR13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijrobp.2010.01.071","volume":"80","author":"F Ricchetti","year":"2011","unstructured":"Ricchetti F, Wu B, McNutt T et al (2011) Volumetric change of selected organs at risk during IMRT for oropharyngeal cancer. Int J Radiat Oncol Biol Phys 80:161\u2013168","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR14","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.ijrobp.2007.10.063","volume":"70","author":"EM V\u00e1squez Osorio","year":"2008","unstructured":"V\u00e1squez Osorio EM, Hoogeman MS, Al-Mamgani A et al (2008) Local anatomical changes in parotid and submandibular glands during radiotherapy for oropharynx cancer and correction with dose, studied in detail with non-rigid registration. Int J Radiat Oncol Biol Phys 70:875\u2013882","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR15","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S0360-3016(01)01749-7","volume":"51","author":"Intensity Modulated Radiation Therapy Collaborative Working Group","year":"2001","unstructured":"Intensity Modulated Radiation Therapy Collaborative Working Group (2001) Intensity-modulated radiotherapy: current status and issues of interest. Int J Radiat Oncol Biol Phys 51:880\u2013914","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR16","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.ijrobp.2006.06.013","volume":"66","author":"EH Pow","year":"2006","unstructured":"Pow EH, Kwong DL, McMillan AS et al (2006) Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial. Int J Radiat Oncol Biol Phys 66:981\u2013991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.meddos.2005.12.004","volume":"31","author":"L Xing","year":"2006","unstructured":"Xing L, Thorndyke B, Schreibmann E et al (2006) Overview of image guided radiation therapy. Med Dosim 31:91\u2013112","journal-title":"Med Dosim"},{"key":"326_CR18","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/nrc2288","volume":"7","author":"D Verellen","year":"2007","unstructured":"Verellen D, Ridder MD, Linthout N et al (2007) Innovations in image-guided radiotherapy. Nat Rev Cancer 7:949\u2013960","journal-title":"Nat Rev Cancer"},{"key":"326_CR19","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1470-2045(08)70098-6","volume":"9","author":"L Veldeman","year":"2008","unstructured":"Veldeman L, Madani I, Hulstaert F et al (2008) Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies. Lancet Oncol 9:367\u2013375","journal-title":"Lancet Oncol"},{"key":"326_CR20","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1470-2045(10)70290-4","volume":"12","author":"CM Nutting","year":"2011","unstructured":"Nutting CM, Morden JP, Harrington KJ et al (2011) Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncol 12:127\u2013136","journal-title":"Lancet Oncol"},{"key":"326_CR21","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.ijrobp.2007.09.054","volume":"70","author":"L Lee","year":"2008","unstructured":"Lee L, Le QT, Xing L (2008) Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file. Int J Radiat Oncol Biol Phys 70:634\u2013644","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR22","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.ijrobp.2006.08.031","volume":"66","author":"S Too","year":"2006","unstructured":"Too S, Yin FF (2006) Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning. Int J Radiat Oncol Biol Phys 66:1553\u20131561","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR23","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ijrobp.2009.04.013","volume":"76","author":"LB Marks","year":"2010","unstructured":"Marks LB, Yorke ED, Jackson A et al (2010) Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys 76:S3\u2013S9","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR24","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.radonc.2010.08.005","volume":"97","author":"GX Ding","year":"2010","unstructured":"Ding GX, Munro P, Pawlowski J, Malcom A, Coffey CW (2010) Reducing radiation exposure to patients from kV-CBCT imaging. Radiother Oncol 97:585\u2013592","journal-title":"Radiother Oncol"},{"issue":"3","key":"326_CR25","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.radonc.2006.12.008","volume":"82","author":"E Donovan","year":"2007","unstructured":"Donovan E, Bleakley N, Denholm E et al (2007) Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 82(3):254\u2013264","journal-title":"Radiother Oncol"},{"key":"326_CR26","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1007\/s11547-011-0765-7","volume":"117","author":"B Bari De","year":"2012","unstructured":"De Bari B, Erraisse MA, Chekrine T et al (2012) Does weight loss predict accuracy of setup in head and neck cancer patients treated with Intensity-Modulated Radiation Therapy? Radiol Med 117:885\u2013891","journal-title":"Radiol Med"},{"key":"326_CR27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.clon.2010.09.003","volume":"23","author":"H Loo","year":"2011","unstructured":"Loo H, Fairfoul J, Chakrabarti A et al (2011) Tumor shrinkage and contour change during radiotherapy increase the dose to Organs at risk but not the target volumes for head and neck cancer patients treated on the tomotherapy HiArtTM System. Clin Oncol 23:40\u201347","journal-title":"Clin Oncol"},{"key":"326_CR28","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.radonc.2011.06.011","volume":"101","author":"P Castadot","year":"2011","unstructured":"Castadot P, Geets X, Lee JA, Gregoire V (2011) Adaptive functional image guided IMRT in pharyngo-laringeal squamous cell carcinoma: is the gain in dose distribution worth the effort? Radiother Oncol 101:343\u2013350","journal-title":"Radiother Oncol"},{"issue":"3","key":"326_CR29","doi-asserted-by":"crossref","first-page":"e375","DOI":"10.1016\/j.ijrobp.2011.07.004","volume":"82","author":"FK Ho","year":"2012","unstructured":"Ho FK, Marchant T, Moore C et al (2012) Monitoring dosimetric impact of weight loss with kilovoltage (kV) cone beam CT (CBCT) during parotid-sparing IMRT and concurrent chemotherapy. Int J Radiat Oncol Biol Phys 82(3):e375\u2013e382","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR30","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.ijrobp.2004.12.035","volume":"62","author":"AWT Konings","year":"2005","unstructured":"Konings AWT, Cotteleer F, Faber H et al (2005) Volume effects and region-dependent radiosensitivity of the parotid gland. Int J Radiat Oncol Biol Phys 62:1090\u20131095","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"326_CR31","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.ijrobp.2009.03.039","volume":"74","author":"P Luuk Van","year":"2009","unstructured":"Van Luuk P, Faber H, Schippers JM et al (2009) Bath and shower effects in the rat parotid gland explain increased relative risk of parotid gland dysfunction after intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys 74:1002\u20131005","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"8","key":"326_CR32","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3109\/0284186X.2012.673735","volume":"51","author":"R Autorino","year":"2012","unstructured":"Autorino R, Miccich\u00e8 F, Dinapoli N et al (2012) Recurrence in region of spared parotid gland in patient receiving definitive intensity-modulated radiotherapy for nasopharyngeal cancer: a case report. Acta Oncol 51(8):1095\u20131099","journal-title":"Acta Oncol"},{"key":"326_CR33","doi-asserted-by":"crossref","unstructured":"Fiorentino A, Cozzolino M, Caivano R et al (2013) Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: parotid glands.Clin Transl Oncol 15(5):412\u2013415","DOI":"10.1007\/s12094-012-0946-4"}],"container-title":["La radiologia medica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-013-0326-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11547-013-0326-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-013-0326-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T13:53:15Z","timestamp":1647697995000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11547-013-0326-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,12]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["326"],"URL":"https:\/\/doi.org\/10.1007\/s11547-013-0326-3","relation":{},"ISSN":["0033-8362","1826-6983"],"issn-type":[{"value":"0033-8362","type":"print"},{"value":"1826-6983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,12]]}}}