{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T17:10:49Z","timestamp":1782321049654,"version":"3.54.5"},"reference-count":70,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T00:00:00Z","timestamp":1606348800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T00:00:00Z","timestamp":1606348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s11547-020-01306-8","type":"journal-article","created":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T08:02:28Z","timestamp":1606377748000},"page":"585-598","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Systemic mastocytosis revisited with an emphasis on skeletal manifestations"],"prefix":"10.1007","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3669-6321","authenticated-orcid":false,"given":"Antonio","family":"Leone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Criscuolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Consolato","family":"Gull\u00ec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Petrosino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Carlo Bianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Colosimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,26]]},"reference":[{"key":"1306_CR1","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.4049\/jimmunol.146.5.1410","volume":"146","author":"AS Kirshenbaum","year":"1991","unstructured":"Kirshenbaum AS, Kessler SW, Goff JP, Metcalfe DD (1991) Demonstration of the origin of humanmast cells from CD34\u2009+\u2009bone marrow progenitor cells. J Immunol 146:1410\u20131415","journal-title":"J Immunol"},{"key":"1306_CR2","doi-asserted-by":"publisher","first-page":"620","DOI":"10.3389\/fimmu.2015.00620","volume":"6","author":"M Krystel-Whittemore","year":"2016","unstructured":"Krystel-Whittemore M, Dileepan KN, Wood JG (2016) Mast cell A. Multi-functional master cell. Front Immunol 6:620. https:\/\/doi.org\/10.3389\/fimmu.2015.00620","journal-title":"Front Immunol"},{"issue":"10","key":"1306_CR3","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1369\/0022155414545334","volume":"62","author":"EZ da Silva","year":"2014","unstructured":"da Silva EZ, Jamur MC, Oliver C (2014) Mast cell function: a new vision of an old cell. J Histochem Cytochem 62(10):698\u2013738","journal-title":"J Histochem Cytochem"},{"issue":"7","key":"1306_CR4","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1182\/blood.V94.7.2333.419k30_2333_2342","volume":"94","author":"AS Kirshenbaum","year":"1999","unstructured":"Kirshenbaum AS, Goff JP, Semere T, Foster B, Scott LM, Metcalfe DD (1999) Demonstration that human mast cells arise from a progenitor cell population that is CD34(\u2009+\u2009), c-kit (+), and expresses aminopeptidase N (CD13). Blood 94(7):2333\u20132342","journal-title":"Blood"},{"key":"1306_CR5","volume-title":"WHO classification of tumors of hematopoietic and lymphoid tissues","author":"HP Horny","year":"2017","unstructured":"Horny HP, Metcalfe DD, Akin C et al (2017) Mastocytosis. In: Swerdlow SH et al (eds) WHO classification of tumors of hematopoietic and lymphoid tissues. International Agency for Research and Cancer , Lyon"},{"issue":"3","key":"1306_CR6","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/ajh.25371","volume":"94","author":"A Pardanani","year":"2019","unstructured":"Pardanani A (2019) Systemic mastocytosis in adults: 2019 update on diagnosis, risk stratification and management. Am J Hematol 94(3):363\u2013377","journal-title":"Am J Hematol"},{"issue":"2","key":"1306_CR7","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1189\/jlb.0512245","volume":"93","author":"Y Amagai","year":"2013","unstructured":"Amagai Y, Tanaka A, Matsuda A, Jung K, Ohmori K, Matsuda H (2013) Stem cell factor contributes to tumorigenesis of mast cells via an autocrine\/paracrine mechanism. J Leukoc Biol 93(2):245\u2013250","journal-title":"J Leukoc Biol"},{"issue":"20","key":"1306_CR8","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1182\/blood-2016-03-643544","volume":"127","author":"DA Arber","year":"2016","unstructured":"Arber DA, Orazi A, Hasserjian R et al (2016) The 2016 revision to the world health organization classification of myeloid neoplasms and acute leukemia. Blood 127(20):2391\u20132405","journal-title":"Blood"},{"issue":"40","key":"1306_CR9","doi-asserted-by":"crossref","first-page":"66299","DOI":"10.18632\/oncotarget.11812","volume":"7","author":"J Monnier","year":"2016","unstructured":"Monnier J, Georgin-Lavialle S, Canioni D et al (2016) Mast cell sarcoma: new cases and literature review. Oncotarget 7(40):66299\u201366309","journal-title":"Oncotarget"},{"key":"1306_CR10","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.beha.2005.07.010","volume":"19","author":"A Pardanani","year":"2006","unstructured":"Pardanani A, Akin C, Valent P (2006) Pathogenesis, clinical features, and treatment advances in mastocytosis. Best Pract Res Clin Haematol 19:595\u2013615","journal-title":"Best Pract Res Clin Haematol"},{"key":"1306_CR11","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/00005792-198811000-00001","volume":"67","author":"WD Travis","year":"1988","unstructured":"Travis WD, Li CY, Bergstralh EJ, Yam LT, Swee RG (1988) Systemic mast cell disease. Analysis of 58 cases and literature review. Med (Baltim) 67:345\u2013368","journal-title":"Med (Baltim)"},{"key":"1306_CR12","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1146\/annurev.med.55.091902.103822","volume":"55","author":"C Akin","year":"2004","unstructured":"Akin C, Metcalfe DD (2004) Systemic mastocytosis. Annu Rev Med 55:419\u2013432","journal-title":"Annu Rev Med"},{"issue":"4","key":"1306_CR13","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s00432-019-03119-3","volume":"146","author":"P Riffel","year":"2020","unstructured":"Riffel P, Schwaab J, Lutz C et al (2020) An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis. J Cancer Res Clin Oncol 146(4):945\u2013951","journal-title":"J Cancer Res Clin Oncol"},{"issue":"10","key":"1306_CR14","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1136\/ard.2009.124511","volume":"69","author":"S Barete","year":"2010","unstructured":"Barete S, Assous N, de Gennes C et al (2010) Systemic mastocytosis and bone involvement in a cohort of 75 patients. Ann Rheum Dis 69(10):1838\u20131841","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"1306_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ageing\/25.1.1","volume":"25","author":"C Johansson","year":"1996","unstructured":"Johansson C, Roupe G, Lindstedt G, Mellstr\u00f6m D (1996) Bone density, bone markers and bone radiological features in mastocytosis. Age Ageing 25(1):1\u20137","journal-title":"Age Ageing"},{"key":"1306_CR16","doi-asserted-by":"publisher","first-page":"163","DOI":"10.3389\/fimmu.2020.00163","volume":"11","author":"D Ragipoglu","year":"2020","unstructured":"Ragipoglu D, Dudeck A, Haffner-Luntzer M et al (2020) The role of mast cells in bone metabolism and bone disorders. Front Immunol 11:163. https:\/\/doi.org\/10.3389\/fimmu.2020.00163","journal-title":"Front Immunol"},{"issue":"1","key":"1306_CR17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.semarthrit.2006.03.004","volume":"36","author":"N Chiappetta","year":"2006","unstructured":"Chiappetta N, Gruber B (2006) The role of mast cells in osteoporosis. Semin Arthritis Rheum 36(1):32\u201336","journal-title":"Semin Arthritis Rheum"},{"issue":"4","key":"1306_CR18","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/BF00310402","volume":"55","author":"MJ McKenna","year":"1994","unstructured":"McKenna MJ (1994) Histomorphometric study of mast cells in normal bone, osteoporosis and mastocytosis using a new stain. Calcif Tissue Int 55(4):257\u2013259","journal-title":"Calcif Tissue Int"},{"key":"1306_CR19","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.bone.2007.04.190","volume":"41","author":"A Irie","year":"2007","unstructured":"Irie A, Takami M, Kubo H, Sekino-Suzuki N, Kasahara K, Sanai Y (2007) Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity. Bone 41:165\u2013174","journal-title":"Bone"},{"issue":"4","key":"1306_CR20","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1159\/000063858","volume":"128","author":"TC Theoharides","year":"2002","unstructured":"Theoharides TC, Boucher W, Spear K (2002) Serum interleukin-6 reflects disease severity and osteoporosis in mastocytosis patients. Int Arch Allergy Immunol 128(4):344\u2013350","journal-title":"Int Arch Allergy Immunol"},{"issue":"12","key":"1306_CR21","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.amjmed.2008.06.036","volume":"121","author":"M Kinjo","year":"2008","unstructured":"Kinjo M, Setoguchi S, Solomon DH (2008) Anti-histamine therapy and bone mineral density: analysis in a population-based U.S. sample. Am J Med 121(12):1085\u20131091","journal-title":"Am J Med"},{"issue":"3","key":"1306_CR22","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.iac.2018.04.013","volume":"38","author":"G Orsolini","year":"2018","unstructured":"Orsolini G, Viapiana O, Rossini M, Bonifacio M, Zanotti R (2018) Bone disease in mastocytosis. Immunol Allergy Clin North Am 38(3):443\u2013454","journal-title":"Immunol Allergy Clin North Am"},{"key":"1306_CR23","doi-asserted-by":"publisher","first-page":"169","DOI":"10.11604\/pamj.2019.32.169.16640","volume":"32","author":"VV Garla","year":"2019","unstructured":"Garla VV, Chaudhary KUQ, Yaqub A (2019) Systemic mastocytosis: a rare cause of osteoporosis. Pan Afr Med J 32:169. https:\/\/doi.org\/10.11604\/pamj.2019.32.169.16640","journal-title":"Pan Afr Med J"},{"issue":"4","key":"1306_CR24","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.2353\/ajpath.2009.080871","volume":"174","author":"M Biosse-Duplan","year":"2009","unstructured":"Biosse-Duplan M, Baroukh B, Dy M, de Vernejoul MC, Saffar JL (2009) Histamine promotes osteoclastogenesis through the differential expression of histamine receptors on osteoclasts and osteoblasts. Am J Pathol 174(4):1426\u20131434","journal-title":"Am J Pathol"},{"key":"1306_CR25","first-page":"281","volume":"279","author":"C de Gennes","year":"1992","unstructured":"de Gennes C, Kuntz D, de Vernejoul MC (1992) Bone mastocytosis. A report of nine cases with a bone histomorphometric study. Clin Orthop Relat Res 279:281\u2013291","journal-title":"Clin Orthop Relat Res"},{"issue":"12","key":"1306_CR26","doi-asserted-by":"publisher","first-page":"2976","DOI":"10.3390\/ijms20122976","volume":"20","author":"P Valent","year":"2019","unstructured":"Valent P, Akin C, Gleixner KV et al (2019) Multidisciplinary challenges in mastocytosis and how to address with personalized medicine approaches. Int J Mol Sci 20(12):2976. https:\/\/doi.org\/10.3390\/ijms20122976","journal-title":"Int J Mol Sci"},{"issue":"23","key":"1306_CR27","doi-asserted-by":"crossref","first-page":"5727","DOI":"10.1182\/blood-2009-02-205237","volume":"113","author":"KH Lim","year":"2009","unstructured":"Lim KH, Tefferi A, Lasho TL et al (2009) Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood 113(23):5727\u20135736","journal-title":"Blood"},{"issue":"3","key":"1306_CR28","first-page":"238","volume":"19","author":"CJ Kurian","year":"2014","unstructured":"Kurian CJ, Madhavan I, Krishnankutty PK, Andrews MA (2014) Compressive myelopathy caused by isolated epidural myeloid sarcoma with systemic mastocytosis. Rare presentation of a hematological malignancy. Neurosciences 19(3):238\u2013239 (Riyadh)","journal-title":"Neurosciences"},{"key":"1306_CR29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.wneu.2019.08.185","volume":"133","author":"A Zafar","year":"2020","unstructured":"Zafar A, Frygier A, Strickland S, Turney R, Spink G (2020) A rare case of spinal mastocytosis presenting as an extradural mass. World Neurosurg 133:17\u201320","journal-title":"World Neurosurg"},{"issue":"19","key":"1306_CR30","first-page":"1885","volume":"373","author":"TC Theoharides","year":"2015","unstructured":"Theoharides TC, Valent P, Akin C (2015) Mast cells, mastocytosis, and related disorders. N Engl J Med 373(19):1885\u20131886","journal-title":"N Engl J Med"},{"issue":"5","key":"1306_CR31","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/ajh.23426","volume":"88","author":"JH Butterfield","year":"2013","unstructured":"Butterfield JH, Weiler CR (2013) Systemic mastocytosis in the elderly. Am J Hematol 88(5):406\u2013408","journal-title":"Am J Hematol"},{"issue":"12","key":"1306_CR32","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1007\/s10067-007-0651-9","volume":"26","author":"T Harzy","year":"2007","unstructured":"Harzy T, El Hajjaji A (2007) Osseous mastocytosis of the knee. Clin Rheumatol 26(12):2171\u20132172","journal-title":"Clin Rheumatol"},{"key":"1306_CR33","first-page":"126","volume":"16","author":"JL Delsignore","year":"1996","unstructured":"Delsignore JL, Dvoretsky PM, Hicks DG, O\u2019Keefe RJ, Rosier RN (1996) Mastocytosis presenting as a skeletal disorder. Iowa Orthop J 16:126\u2013134","journal-title":"Iowa Orthop J"},{"issue":"8","key":"1306_CR34","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1007\/s00256-012-1374-9","volume":"41","author":"J Fritz","year":"2012","unstructured":"Fritz J, Fishman EK, Carrino JA, Horger MS (2012) Advanced imaging of skeletal manifestations of systemic mastocytosis. Skeletal Radiol 41(8):887\u2013897","journal-title":"Skeletal Radiol"},{"issue":"11","key":"1306_CR35","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s00256-007-0308-4","volume":"36","author":"S Hwang","year":"2007","unstructured":"Hwang S, Panicek DM (2007) Magnetic resonance imaging of bone marrow in oncology, part 2. Skeletal Radiol 36(11):1017\u20131027","journal-title":"Skeletal Radiol"},{"issue":"6","key":"1306_CR36","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.2214\/AJR.11.7005","volume":"197","author":"LM Shah","year":"2011","unstructured":"Shah LM, Hanrahan CJ (2011) MRI of spinal bone marrow: part I, techniques and normal age-related appearances. AJR Am J Roentgenol 197(6):1298\u20131308","journal-title":"AJR Am J Roentgenol"},{"key":"1306_CR37","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1302\/0301-620X.74B4.1624505","volume":"74","author":"IT Benli","year":"1992","unstructured":"Benli IT, Akalin S, Boysan E et al (1992) Epidemiological, clinical and radiological aspects of osteopoikilosis. J Bone Jt Surg Br 74:504\u2013506","journal-title":"J Bone Jt Surg Br"},{"issue":"9","key":"1306_CR38","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s003300000495","volume":"10","author":"FM Vanhoenacker","year":"2000","unstructured":"Vanhoenacker FM, De Beuckeleer LH, Van Hul W et al (2000) Sclerosing bone dysplasias: genetic and radioclinical features. Eur Radiol 10(9):1423\u20131433","journal-title":"Eur Radiol"},{"issue":"7","key":"1306_CR39","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1148\/rg.317115093","volume":"31","author":"LL Ihde","year":"2011","unstructured":"Ihde LL, Forrester DM, Gottsegen CJ et al (2011) Sclerosing bone dysplasias: review and differentiation from other causes of osteosclerosis. Radiographics 31(7):1865\u20131882","journal-title":"Radiographics"},{"issue":"6","key":"1306_CR40","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/BF01622200","volume":"4","author":"JA Kanis","year":"1994","unstructured":"Kanis JA (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report WHO Study Group. Osteoporos Int 4(6):368\u2013381","journal-title":"Osteoporos Int"},{"key":"1306_CR41","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.bone.2017.09.005","volume":"105","author":"Y Degbo\u00e9","year":"2017","unstructured":"Degbo\u00e9 Y, Eischen M, Nigon D et al (2017) Prevalence and risk factors for fragility fracture in systemic mastocytosis. Bone 105:219\u2013225","journal-title":"Bone"},{"issue":"4","key":"1306_CR42","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.bone.2011.07.004","volume":"49","author":"M Rossini","year":"2011","unstructured":"Rossini M, Zanotti R, Bonadonna P et al (2011) Bone mineral density, bone turnover markers and fractures in patients with indolent systemic mastocytosis. Bone 49(4):880\u2013885","journal-title":"Bone"},{"issue":"9","key":"1306_CR43","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","volume":"8","author":"HK Genant","year":"1993","unstructured":"Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8(9):1137\u20131148","journal-title":"J Bone Miner Res"},{"issue":"3","key":"1306_CR44","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1398-9995.2011.02780.x","volume":"67","author":"E van der Veer","year":"2012","unstructured":"van der Veer E, van der Goot W, de Monchy JG, Kluin-Nelemans HC, van Doormaal JJ (2012) High prevalence of fractures and osteoporosis in patients with indolent systemic mastocytosis. Allergy 67(3):431\u2013438","journal-title":"Allergy"},{"issue":"3","key":"1306_CR45","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jbspin.2012.01.003","volume":"79","author":"L Frenzel","year":"2012","unstructured":"Frenzel L, Suarez F, Chandesris MO, Hermine O (2012) Ivory vertebra and systemic mastocytosis. Jt Bone Spine 79(3):319\u2013321","journal-title":"Jt Bone Spine"},{"issue":"2","key":"1306_CR46","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3941\/jrcr.v9i2.2264","volume":"9","author":"M Chehab","year":"2015","unstructured":"Chehab M, Copelan A, Al-faham Z, Bahoura L, Wong CY (2015) Systemic mastocytosis: a rare cause of single vertebral body uptake on bone scan. J Radiol Case Rep 9(2):31\u201341","journal-title":"J Radiol Case Rep"},{"issue":"11","key":"1306_CR47","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1002\/jbmr.5650051104","volume":"5","author":"L Graves 3rd","year":"1990","unstructured":"Graves L 3rd, Stechschulte DJ, Morris DC, Lukert BP (1990) Inhibition of mediator release in systemic mastocytosis is associated with reversal of bone changes. J Bone Miner Res 5(11):1113\u20131119","journal-title":"J Bone Miner Res"},{"issue":"9","key":"1306_CR48","first-page":"1471","volume":"35","author":"CC Chen","year":"1994","unstructured":"Chen CC, Andrich MP, Mican JM, Metcalfe DD (1994) A retrospective analysis of bone scan abnormalities in mastocytosis: correlation with disease category and prognosis. J Nucl Med 35(9):1471\u20131475","journal-title":"J Nucl Med"},{"issue":"3","key":"1306_CR49","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s002560050350","volume":"27","author":"NA Avila","year":"1998","unstructured":"Avila NA, Ling A, Metcalfe DD, Worobec AS (1998) Mastocytosis: magnetic resonance imaging patterns of marrow disease. Skeletal Radiol 27(3):119\u2013126","journal-title":"Skeletal Radiol"},{"issue":"1","key":"1306_CR50","doi-asserted-by":"crossref","first-page":"142","DOI":"10.2106\/00004623-196850010-00009","volume":"50","author":"M Barer","year":"1968","unstructured":"Barer M, Peterson LF, Dahlin DC, Winkelmann RK, Stewart JR (1968) Mastocytosis with osseous lesions resembling metastatic malignant lesions in bone. J Bone Jt Surg Am 50(1):142\u2013152","journal-title":"J Bone Jt Surg Am"},{"issue":"5","key":"1306_CR51","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1148\/rg.315105712","volume":"31","author":"G Guglielmi","year":"2011","unstructured":"Guglielmi G, Muscarella S, Bazzocchi A (2011) Integrated imaging approach to osteoporosis: state-of-the-art review and update. Radiographics 31(5):1343\u20131364","journal-title":"Radiographics"},{"key":"1306_CR52","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00330-007-0738-3","volume":"18","author":"P Kropil","year":"2008","unstructured":"Kropil P, Fenk R, Fritz LB et al (2008) Comparison of whole-body 64-slice multidetector computed tomography and conventional radiography in staging of multiple myeloma. Eur Radiol 18:51\u201358","journal-title":"Eur Radiol"},{"issue":"2","key":"1306_CR53","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.21873\/anticanres.14036","volume":"40","author":"HJ Meyer","year":"2020","unstructured":"Meyer HJ, P\u00f6nisch W, Monecke A, Gundermann P, Surov A (2020) Can diagnostic low-dose whole-body CT reflect bone marrow findings in systemic mastocytosis? Anticancer Res 40(2):1015\u20131022","journal-title":"Anticancer Res"},{"key":"1306_CR54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s002560050056","volume":"25","author":"K Haney","year":"1996","unstructured":"Haney K, Russell W, Raila FA, Brower AC, Harrison RB (1996) MRI characteristics of systemic mastocytosis of the lumbosacral spine. Skeletal Radiol 25:171\u2013173","journal-title":"Skeletal Radiol"},{"issue":"6","key":"1306_CR55","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1007\/s003300050796","volume":"9","author":"M Roca","year":"1999","unstructured":"Roca M, Mota J, Giraldo P, Garc\u00eda Erce JA (1999) Systemic mastocytosis: MRI of bone marrow involvement. Eur Radiol 9(6):1094\u20131097","journal-title":"Eur Radiol"},{"issue":"3 Suppl","key":"1306_CR56","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.2214\/AJR.09.7069","volume":"193","author":"PG Swartz","year":"2009","unstructured":"Swartz PG, Roberts CC (2009) Radiological reasoning: bone marrow changes on MRI. AJR Am J Roentgenol 193(3 Suppl):S1-4","journal-title":"AJR Am J Roentgenol"},{"issue":"3","key":"1306_CR57","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1007\/s00330-006-0404-1","volume":"17","author":"HE Daldrup-Link","year":"2007","unstructured":"Daldrup-Link HE, Henning T, Link TM (2007) MR imaging of therapy-induced changes of bone marrow. Eur Radiol 17(3):743\u2013761","journal-title":"Eur Radiol"},{"key":"1306_CR58","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.crad.2014.01.027","volume":"69","author":"D Dreizin","year":"2014","unstructured":"Dreizin D, Ahlawat S, Del Grande F, Fayad LM (2014) Gradient-echo in-phase and opposed-phase chemical shift imaging: role in evaluating bone marrow. Clin Radiol 69:648\u2013657","journal-title":"Clin Radiol"},{"issue":"3","key":"1306_CR59","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4103\/0971-3026.137049","volume":"24","author":"F Del Grande","year":"2014","unstructured":"Del Grande F, Farahani SJ, Carrino JA, Chhabra A (2014) Bone marrow lesions: a systematic diagnostic approach. Indian J Radiol Imaging 24(3):279\u2013287","journal-title":"Indian J Radiol Imaging"},{"key":"1306_CR60","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1055\/s-2005-858362","volume":"177","author":"K Wasser","year":"2005","unstructured":"Wasser K, Moehler T, Nosas-Garcia S et al (2005) Correlation of MRI and histopathology of bone marrow in patients with multiple myeloma. Rofo 177:1116\u20131122","journal-title":"Rofo"},{"key":"1306_CR61","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1055\/s-0029-1220879","volume":"13","author":"BC Vande Berg","year":"2009","unstructured":"Vande Berg BC, Lecouvet FE, Galant C, Simoni P, Malghem J (2009) Normal variants of the bone marrow at MR imaging of the spine. Semin Musculoskelet Radiol 13:87\u201396","journal-title":"Semin Musculoskelet Radiol"},{"issue":"7","key":"1306_CR62","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s002560050257","volume":"26","author":"A Baur","year":"1997","unstructured":"Baur A, St\u00e4bler A, Bartl R, Lamerz R, Scheidler J, Reiser M (1997) MRI gadolinium enhancement of bone marrow: age-related changes in normals and in diffuse neoplastic infiltration. Skelet Radiol 26(7):414\u2013418","journal-title":"Skelet Radiol"},{"issue":"6","key":"1306_CR63","doi-asserted-by":"crossref","first-page":"W336","DOI":"10.2214\/AJR.17.17984","volume":"209","author":"M Morone","year":"2017","unstructured":"Morone M, Bali MA, Tunariu N et al (2017) Whole-body MRI: current applications in oncology. AJR Am J Roentgenol 209(6):W336\u2013W349","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"1306_CR64","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1148\/radiol.2016142084","volume":"279","author":"FE Lecouvet","year":"2016","unstructured":"Lecouvet FE (2016) Whole-body MR Imaging: musculoskeletal applications. Radiology 279(2):345\u2013365","journal-title":"Radiology"},{"issue":"12","key":"1306_CR65","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1007\/s00277-019-03826-4","volume":"98","author":"P Riffel","year":"2019","unstructured":"Riffel P, Jawhar M, Gawlik K et al (2019) Magnetic resonance imaging reveals distinct bone marrow patterns in indolent and advanced systemic mastocytosis. Ann Hematol 98(12):2693\u20132701","journal-title":"Ann Hematol"},{"issue":"3","key":"1306_CR66","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1148\/radiol.11110474","volume":"261","author":"AR Padhani","year":"2011","unstructured":"Padhani AR, Koh DM, Collins DJ (2011) Whole-body diffusion-weighted MR imaging in cancer: current status and research directions. Radiology 261(3):700\u2013718","journal-title":"Radiology"},{"issue":"12","key":"1306_CR67","first-page":"2046","volume":"30","author":"ER Arrington","year":"1989","unstructured":"Arrington ER, Eisenberg B, Hartshorne MF, Vela S, Dorin RI (1989) Nuclear medicine imaging of systemic mastocytosis. J Nucl Med 30(12):2046\u20132048","journal-title":"J Nucl Med"},{"issue":"5","key":"1306_CR68","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.2214\/ajr.179.5.1791235","volume":"179","author":"G Zettinig","year":"2002","unstructured":"Zettinig G, Becherer A, Szabo M et al (2002) FDG positron emission tomography in patients with systemic mastocytosis. AJR Am J Roentgenol 179(5):1235\u20131237","journal-title":"AJR Am J Roentgenol"},{"issue":"13","key":"1306_CR69","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1007\/s00259-015-3117-3","volume":"42","author":"S Djelbani-Ahmed","year":"2015","unstructured":"Djelbani-Ahmed S, Chandesris MO, Mekinian A et al (2015) FDG-PET\/CT findings in systemic mastocytosis: a French multicentre study. Eur J Nucl Med Mol Imaging 42(13):2013\u20132020","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"1306_CR70","doi-asserted-by":"crossref","unstructured":"Rossignol J, Polivka L, Maouche-Chr\u00e9tien L, et al (2019) Recent advances in the understanding and therapeutic management of mastocytosis. F1000Res 22;8:F1000 Faculty Rev-1961","DOI":"10.12688\/f1000research.19463.1"}],"container-title":["La radiologia medica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-020-01306-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11547-020-01306-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-020-01306-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:56:35Z","timestamp":1697244995000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11547-020-01306-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,26]]},"references-count":70,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["1306"],"URL":"https:\/\/doi.org\/10.1007\/s11547-020-01306-8","relation":{},"ISSN":["0033-8362","1826-6983"],"issn-type":[{"value":"0033-8362","type":"print"},{"value":"1826-6983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,26]]},"assertion":[{"value":"26 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}