{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T04:05:24Z","timestamp":1783656324849,"version":"3.55.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T00:00:00Z","timestamp":1652313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T00:00:00Z","timestamp":1652313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s11547-022-01498-1","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T13:04:16Z","timestamp":1652360656000},"page":"627-636","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Management of vertebral compression fractures: the role of dual-energy CT in clinical practice"],"prefix":"10.1007","volume":"127","author":[{"given":"Giovanni","family":"Foti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-5830","authenticated-orcid":false,"given":"Fabio","family":"Lombardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Guerriero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Rodella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo","family":"Cicci\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niccol\u00f2","family":"Faccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Manenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,12]]},"reference":[{"issue":"4","key":"1498_CR1","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1007\/s00256-013-1812-3","volume":"43","author":"G Bierry","year":"2014","unstructured":"Bierry G, Venkatasamy A, Kremer S, Dosch JC, Dietemann JL (2014) Dual-energy CT in vertebral compression fractures: performance of visual and quantitative analysis for bone marrow edema demonstration with comparison to MRI. Skelet Radiol 43(4):485\u2013492. https:\/\/doi.org\/10.1007\/s00256-013-1812-3","journal-title":"Skelet Radiol"},{"issue":"7","key":"1498_CR2","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/s001980070078","volume":"11","author":"SH Gehlbach","year":"2000","unstructured":"Gehlbach SH, Bigelow C, Heimisdottir M, May S, Walker M, Kirkwood JR (2000) Recognition of vertebral fracture in a clinical setting. Osteoporos Int 11(7):577\u2013582. https:\/\/doi.org\/10.1007\/s001980070078","journal-title":"Osteoporos Int"},{"issue":"1","key":"1498_CR3","first-page":"111","volume":"69","author":"JL Old","year":"2004","unstructured":"Old JL, Calvert M (2004) Vertebral compression fractures in the elderly. Am Fam Phys 69(1):111\u2013116","journal-title":"Am Fam Phys"},{"issue":"4","key":"1498_CR4","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1055\/s-0036-1592431","volume":"20","author":"F Aparisi","year":"2016","unstructured":"Aparisi F (2016) Vertebroplasty and kyphoplasty in vertebral osteoporotic fractures. Semin Musculoskelet Radiol 20(4):382\u2013391. https:\/\/doi.org\/10.1055\/s-0036-1592431","journal-title":"Semin Musculoskelet Radiol"},{"issue":"12","key":"1498_CR5","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1007\/s00270-017-1779-x","volume":"40","author":"DK Filippiadis","year":"2017","unstructured":"Filippiadis DK, Marcia S, Masala S, Deschamps F, Kelekis A (2017) Percutaneous Vertebroplasty and Kyphoplasty: current status, new developments and old controversies. Cardiovasc Interven Radiol 40(12):1815\u20131823. https:\/\/doi.org\/10.1007\/s00270-017-1779-x","journal-title":"Cardiovasc Interven Radiol"},{"issue":"5","key":"1498_CR6","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s005860000182","volume":"9","author":"PF Heini","year":"2000","unstructured":"Heini PF, Walchli B, Berlemann U (2000) Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fractures. Eur Spine J 9(5):445\u2013450. https:\/\/doi.org\/10.1007\/s005860000182","journal-title":"Eur Spine J"},{"issue":"9746","key":"1498_CR7","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1016\/S0140-6736(10)60954-3","volume":"376","author":"CA Klazen","year":"2010","unstructured":"Klazen CA, Lohle PN, de Vries J, Jansen FH, Tielbeek AV, Blonk MC, Venmans A, van Rooij WJ, Schoemaker MC, Juttmann JR, Lo TH, Verhaar HJ, van der Graaf Y, van Everdingen KJ, Muller AF, Elgersma OE, Halkema DR, Fransen H, Janssens X, Buskens E, Mali WP (2010) Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial. Lancet 376(9746):1085\u20131092. https:\/\/doi.org\/10.1016\/S0140-6736(10)60954-3","journal-title":"Lancet"},{"issue":"3","key":"1498_CR8","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/s0002-9343(02)01190-7","volume":"113","author":"A Papaioannou","year":"2002","unstructured":"Papaioannou A, Watts NB, Kendler DL, Yuen CK, Adachi JD, Ferko N (2002) Diagnosis and management of vertebral fractures in elderly adults. Am J Med 113(3):220\u2013228. https:\/\/doi.org\/10.1016\/s0002-9343(02)01190-7","journal-title":"Am J Med"},{"issue":"31","key":"1498_CR9","doi-asserted-by":"publisher","first-page":"e4491","DOI":"10.1097\/MD.0000000000004491","volume":"95","author":"WH Yuan","year":"2016","unstructured":"Yuan WH, Hsu HC, Lai KL (2016) Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures: a meta-analysis. Medicine 95(31):e4491. https:\/\/doi.org\/10.1097\/MD.0000000000004491","journal-title":"Medicine"},{"issue":"4","key":"1498_CR10","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1227\/01.NEU.0000339120.41053.F1","volume":"64","author":"IH Han","year":"2009","unstructured":"Han IH, Chin DK, Kuh SU, Kim KS, Jin BH, Yoon YS, Cho YE (2009) Magnetic resonance imaging findings of subsequent fractures after vertebroplasty. Neurosurgery 64(4):740\u2013744. https:\/\/doi.org\/10.1227\/01.NEU.0000339120.41053.F1","journal-title":"Neurosurgery"},{"issue":"2","key":"1498_CR11","first-page":"373","volume":"22","author":"JM Mathis","year":"2001","unstructured":"Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H (2001) Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol 22(2):373\u2013381","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"1498_CR12","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1148\/radiol.2391050073","volume":"239","author":"N Tanigawa","year":"2006","unstructured":"Tanigawa N, Komemushi A, Kariya S, Kojima H, Shomura Y, Ikeda K, Omura N, Murakami T, Sawada S (2006) Percutaneous vertebroplasty: relationship between vertebral body bone marrow edema pattern on MR images and initial clinical response. Radiology 239(1):195\u2013200. https:\/\/doi.org\/10.1148\/radiol.2391050073","journal-title":"Radiology"},{"issue":"2","key":"1498_CR13","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1148\/radiol.13122577","volume":"269","author":"CK Wang","year":"2013","unstructured":"Wang CK, Tsai JM, Chuang MT, Wang MT, Huang KY, Lin RM (2013) Bone marrow edema in vertebral compression fractures: detection with dual-energy CT. Radiology 269(2):525\u2013533. https:\/\/doi.org\/10.1148\/radiol.13122577","journal-title":"Radiology"},{"issue":"3","key":"1498_CR14","doi-asserted-by":"publisher","first-page":"387","DOI":"10.3390\/tomography7030034","volume":"7","author":"G Foti","year":"2021","unstructured":"Foti G, Serra G, Iacono V, Marocco S, Bertoli G, Gori S, Zorzi C (2021) Identification of non-traumatic bone marrow oedema: the pearls and pitfalls of dual-energy CT (DECT). Tomography 7(3):387\u2013396. https:\/\/doi.org\/10.3390\/tomography7030034","journal-title":"Tomography"},{"issue":"7","key":"1498_CR15","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1097\/RLI.0000000000000458","volume":"53","author":"C Frellesen","year":"2018","unstructured":"Frellesen C, Azadegan M, Martin SS, Otani K, D\u2019Angelo T, Booz C, Eichler K, Panahi B, Kaup M, Bauer RW, Vogl TJ, Wichmann JL (2018) Dual-energy computed tomography-based display of bone marrow edema in incidental vertebral compression fractures: diagnostic accuracy and characterization in oncological patients undergoing routine staging computed tomography. Investig Radiol 53(7):409\u2013416. https:\/\/doi.org\/10.1097\/RLI.0000000000000458","journal-title":"Investig Radiol"},{"issue":"10","key":"1498_CR16","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1007\/s00256-020-03450-8","volume":"49","author":"SY Jeong","year":"2020","unstructured":"Jeong SY, Jeon SJ, Seol M, Ahn TH, Juhng SK (2020) Diagnostic performance of dual-energy computed tomography for detection of acute spinal fractures. Skelet Radiol 49(10):1589\u20131595. https:\/\/doi.org\/10.1007\/s00256-020-03450-8","journal-title":"Skelet Radiol"},{"issue":"1057","key":"1498_CR17","doi-asserted-by":"publisher","first-page":"20150300","DOI":"10.1259\/bjr.20150300","volume":"89","author":"L Karaca","year":"2016","unstructured":"Karaca L, Yuceler Z, Kantarci M, Cakir M, Sade R, Calikoglu C, Ogul H, Bayrakturan UG (2016) The feasibility of dual-energy CT in differentiation of vertebral compression fractures. Br J Radiol 89(1057):20150300. https:\/\/doi.org\/10.1259\/bjr.20150300","journal-title":"Br J Radiol"},{"issue":"2","key":"1498_CR18","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1148\/radiol.2016150472","volume":"280","author":"M Kaup","year":"2016","unstructured":"Kaup M, Wichmann JL, Scholtz JE, Beeres M, Kromen W, Albrecht MH, Lehnert T, Boettcher M, Vogl TJ, Bauer RW (2016) Dual-energy CT-based display of bone marrow edema in osteoporotic vertebral compression fractures: impact on diagnostic accuracy of radiologists with varying levels of experience in correlation to MR imaging. Radiology 280(2):510\u2013519. https:\/\/doi.org\/10.1148\/radiol.2016150472","journal-title":"Radiology"},{"issue":"1","key":"1498_CR19","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1148\/radiol.2017162165","volume":"284","author":"B Petritsch","year":"2017","unstructured":"Petritsch B, Kosmala A, Weng AM, Krauss B, Heidemeier A, Wagner R, Heintel TM, Gassenmaier T, Bley TA (2017) Vertebral compression fractures: third-generation dual-energy CT for detection of bone marrow edema at visual and quantitative analyses. Radiology 284(1):161\u2013168. https:\/\/doi.org\/10.1148\/radiol.2017162165","journal-title":"Radiology"},{"issue":"6","key":"1498_CR20","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s11547-019-00998-x","volume":"124","author":"G Foti","year":"2019","unstructured":"Foti G, Beltramello A, Catania M, Rigotti S, Serra G, Carbognin G (2019) Diagnostic accuracy of dual-energy CT and virtual non-calcium techniques to evaluate bone marrow edema in vertebral compression fractures. Radiol Med 124(6):487\u2013494. https:\/\/doi.org\/10.1007\/s11547-019-00998-x","journal-title":"Radiol Med"},{"key":"1498_CR21","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.ejrad.2017.12.018","volume":"99","author":"P Yang","year":"2018","unstructured":"Yang P, Wu G, Chang X (2018) Diagnostic accuracy of dual-energy computed tomography in bone marrow edema with vertebral compression fractures: a meta-analysis. Eur J Radiol 99:124\u2013129. https:\/\/doi.org\/10.1016\/j.ejrad.2017.12.018","journal-title":"Eur J Radiol"},{"issue":"11","key":"1498_CR22","doi-asserted-by":"publisher","first-page":"2357","DOI":"10.1007\/s00330-012-2501-7","volume":"22","author":"R Guggenberger","year":"2012","unstructured":"Guggenberger R, Winklhofer S, Osterhoff G, Wanner GA, Fortunati M, Andreisek G, Alkadhi H, Stolzmann P (2012) Metallic artefact reduction with monoenergetic dual-energy CT: systematic ex vivo evaluation of posterior spinal fusion implants from various vendors and different spine levels. Eur Radiol 22(11):2357\u20132364. https:\/\/doi.org\/10.1007\/s00330-012-2501-7","journal-title":"Eur Radiol"},{"issue":"5","key":"1498_CR23","doi-asserted-by":"publisher","first-page":"e67","DOI":"10.1016\/j.acra.2018.06.008","volume":"26","author":"L Horat","year":"2019","unstructured":"Horat L, Hamie MQ, Huber FA, Guggenberger R (2019) Optimization of monoenergetic extrapolations in dual-energy CT for metal artifact reduction in different body regions and orthopedic implants. Acad Radiol 26(5):e67\u2013e74. https:\/\/doi.org\/10.1016\/j.acra.2018.06.008","journal-title":"Acad Radiol"},{"issue":"8","key":"1498_CR24","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s11547-018-0881-8","volume":"123","author":"N Magarelli","year":"2018","unstructured":"Magarelli N, De Santis V, Marziali G, Menghi A, Burrofato A, Pedone L, Del Prete D, Iezzi R, de Waure C, D\u2019Andrea M, Leone A, Colosimo C (2018) Application and advantages of monoenergetic reconstruction images for the reduction of metallic artifacts using dual-energy CT in knee and hip prostheses. Radiol Med 123(8):593\u2013600. https:\/\/doi.org\/10.1007\/s11547-018-0881-8","journal-title":"Radiol Med"},{"issue":"2","key":"1498_CR25","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1148\/rg.2018170058","volume":"38","author":"JR Wortman","year":"2018","unstructured":"Wortman JR, Uyeda JW, Fulwadhva UP, Sodickson AD (2018) Dual-energy CT for abdominal and pelvic trauma. Radiographics 38(2):586\u2013602. https:\/\/doi.org\/10.1148\/rg.2018170058","journal-title":"Radiographics"},{"key":"1498_CR26","doi-asserted-by":"publisher","first-page":"109456","DOI":"10.1016\/j.ejrad.2020.109456","volume":"134","author":"I Simonetti","year":"2021","unstructured":"Simonetti I, Verde F, Palumbo L, Di Pietto F, Puglia M, Scaglione M, Ragozzino A, Romano S (2021) Dual energy computed tomography evaluation of skeletal traumas. Eur J Radiol 134:109456. https:\/\/doi.org\/10.1016\/j.ejrad.2020.109456","journal-title":"Eur J Radiol"},{"key":"1498_CR27","doi-asserted-by":"publisher","first-page":"115100","DOI":"10.1016\/j.bone.2019.115100","volume":"130","author":"S Catano Jimenez","year":"2020","unstructured":"Catano Jimenez S, Saldarriaga S, Chaput CD, Giambini H (2020) Dual-energy estimates of volumetric bone mineral densities in the lumbar spine using quantitative computed tomography better correlate with fracture properties when compared to single-energy BMD outcomes. Bone 130:115100. https:\/\/doi.org\/10.1016\/j.bone.2019.115100","journal-title":"Bone"},{"issue":"9","key":"1498_CR28","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","volume":"8","author":"HK Genant","year":"1993","unstructured":"Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8(9):1137\u20131148. https:\/\/doi.org\/10.1002\/jbmr.5650080915","journal-title":"J Bone Miner Res"}],"container-title":["La radiologia medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-022-01498-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11547-022-01498-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-022-01498-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T12:20:07Z","timestamp":1653394807000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11547-022-01498-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["1498"],"URL":"https:\/\/doi.org\/10.1007\/s11547-022-01498-1","relation":{},"ISSN":["1826-6983"],"issn-type":[{"value":"1826-6983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,12]]},"assertion":[{"value":"28 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standard of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standard.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained by all patients enrolled for this prospective study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}