{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T08:19:59Z","timestamp":1780647599547,"version":"3.54.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009878","name":"Regione del Veneto","doi-asserted-by":"publisher","award":["968\/DGR of Jul 06"],"award-info":[{"award-number":["968\/DGR of Jul 06"]}],"id":[{"id":"10.13039\/501100009878","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009878","name":"Regione del Veneto","doi-asserted-by":"publisher","award":["2018"],"award-info":[{"award-number":["2018"]}],"id":[{"id":"10.13039\/501100009878","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The optimal mammography screening strategy for women aged 45\u201349\u00a0years is a matter of debate. We present the RIBBS study protocol, a quasi-experimental, prospective, population-based study comparing a risk- and breast density-stratified screening model (interventional cohort) with annual digital mammography (DM) screening (observational control cohort) in a real-world setting. The interventional cohort consists of 10,269 women aged 45\u00a0years enrolled between 2020 and 2021 from two provinces of the Veneto Region\u00a0(northen Italy). At baseline, participants underwent two-view digital breast tomosynthesis (DBT) and completed the Tyrer-Cuzick risk prediction model. Volumetric breast density (VBD) was calculated from DBT and the lifetime risk (LTR) was estimated by including VBD among the risk factors. Based on VBD and LTR, women were classified into five subgroups with specific screening protocols for subsequent screening rounds: (1) LTR\u2009\u2264\u200917% and nondense breast: biennial DBT; (2) LTR\u2009\u2264\u200917% and dense breast: biennial DBT and ultrasound; (3) LTR 17\u201330% or LTR\u2009&gt;\u200930% without family history of BC, and nondense breast: annual DBT; (4) LTR 17\u201330% or\u2009&gt;\u200930% without family history of BC, and dense breast: annual DBT and ultrasound; and (5) LTR\u2009&gt;\u200930% and family history of BC: annual DBT and breast MRI. The interventional cohort is still ongoing. An observational, nonequivalent control cohort of 43,000 women aged 45\u00a0years participating in an annual DM screening programme was recruited in three provinces of the neighbouring Emilia-Romagna Region. Cumulative incidence rates of advanced BC at three, five, and ten years between the two cohorts will be compared, adjusting for the incidence difference at baseline.<\/jats:p><jats:p><jats:italic>Trial registration<\/jats:italic> This study is registered on Clinicaltrials.gov (NCT05675085).<\/jats:p>","DOI":"10.1007\/s11547-024-01797-9","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T12:02:07Z","timestamp":1711022527000},"page":"727-736","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The risk-based breast screening (RIBBS) study protocol: a personalized screening model for young women"],"prefix":"10.1007","volume":"129","clinical-trial-number":[{"clinical-trial-number":"nct05675085","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Gisella","family":"Gennaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6771-8119","authenticated-orcid":false,"given":"Lauro","family":"Bucchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Ravaioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Zorzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Falcini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9457-5176","authenticated-orcid":false,"given":"Francesca","family":"Caumo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"1797_CR1","first-page":"614","volume":"19","author":"N Perry","year":"2008","unstructured":"Perry N, Broeders M, de Wolf C, T\u00f6rnberg S, Holland R, von Karsa L (2008) European guidelines for quality assurance in breast cancer screening and diagnosis. Fourth edition Summary document Ann Oncol 19:614\u2013622","journal-title":"Fourth edition Summary document Ann Oncol"},{"key":"1797_CR2","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1056\/NEJMsr1504363","volume":"372","author":"B Lauby-Secretan","year":"2015","unstructured":"Lauby-Secretan B, Scoccianti C, Loomis D, Benbrahim-Tallaa L, Bouvard V, Bianchini F et al (2015) Breast-cancer screening: viewpoint of the IARC Working Group. N Engl J Med 372:2353\u20132358","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"1797_CR3","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1258\/jms.2012.012085","volume":"19","author":"L Giordano","year":"2012","unstructured":"Giordano L, von Karsa L, Tomatis M, Majek O, de Wolf C, Lancucki L et al (2012) Mammographic screening programmes in Europe: organization, coverage and participation. J Med Screen 19(Suppl 1):72\u201382","journal-title":"J Med Screen"},{"key":"1797_CR4","unstructured":"European Commission Initiative on Breast and Colorectal cancer. https:\/\/healthcare-quality.jrc.ec.europa.eu. Accessed 15 Mar 2023."},{"key":"1797_CR5","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1136\/eb-2014-101798","volume":"19","author":"K Kerlikowske","year":"2014","unstructured":"Kerlikowske K, O\u2019Kane ME, Esserman LJ (2014) Fifty years of age-based screening: time for a new risk-based screening approach. Evid Based Med 19:183","journal-title":"Evid Based Med"},{"key":"1797_CR6","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/978-3-030-16391-4_2","volume":"178","author":"JC Sachdev","year":"2019","unstructured":"Sachdev JC, Sandoval AC, Jahanzeb M (2019) Update on precision medicine in breast cancer. Cancer Treat Res 178:45\u201380","journal-title":"Cancer Treat Res"},{"key":"1797_CR7","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.soc.2019.08.004","volume":"29","author":"I Greenwalt","year":"2020","unstructured":"Greenwalt I, Zaza N, Das S, Li BD (2020) Precision medicine and targeted therapies in breast cancer. Surg Oncol Clin N Am 29:51\u201362","journal-title":"Surg Oncol Clin N Am"},{"key":"1797_CR8","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.3390\/cancers14143469","volume":"14","author":"SM Hacking","year":"2022","unstructured":"Hacking SM, Yakirevich E, Wang Y (2022) From immunohistochemistry to new digital ecosystems: a state-of-the-art biomarker review for precision breast cancer medicine. Cancers 14:3469","journal-title":"Cancers"},{"key":"1797_CR9","doi-asserted-by":"publisher","first-page":"4306","DOI":"10.1245\/s10434-020-09426-1","volume":"28","author":"TM Allweis","year":"2021","unstructured":"Allweis TM, Hermann N, Berenstein-Molho R, Guindy M (2021) Personalized screening for breast cancer: rationale, present practices, and future directions. Ann Surg Oncol 28:4306\u20134317","journal-title":"Ann Surg Oncol"},{"key":"1797_CR10","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1002\/jmri.28495","volume":"57","author":"D C\u00f6mert","year":"2023","unstructured":"C\u00f6mert D, van Gils CH, Veldhuis WB, Mann RM (2023) Challenges and changes of the breast cancer screening paradigm. J Magn Reson Imaging 57:706\u2013726","journal-title":"J Magn Reson Imaging"},{"key":"1797_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.rcl.2020.09.003","volume":"59","author":"CR Saccarelli","year":"2021","unstructured":"Saccarelli CR, Bitencourt AGV, Morris EA (2021) Is it the era for personalized screening? Radiol Clin North Am 59:129\u2013138","journal-title":"Radiol Clin North Am"},{"key":"1797_CR12","doi-asserted-by":"publisher","first-page":"710","DOI":"10.7326\/M21-0398","volume":"174","author":"K Kerlikowske","year":"2021","unstructured":"Kerlikowske K, Bibbins-Domingo K (2021) Toward risk-based breast cancer screening. Ann Intern Med 174:710\u2013711","journal-title":"Ann Intern Med"},{"key":"1797_CR13","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/s41571-020-0388-9","volume":"17","author":"N Pashayan","year":"2020","unstructured":"Pashayan N, Antoniou AC, Ivanus U, Esserman LJ, Easton DF, French D et al (2020) Personalized early detection and prevention of breast cancer: ENVISION consensus statement. Nat Rev Clin Oncol 17:687\u2013705","journal-title":"Nat Rev Clin Oncol"},{"key":"1797_CR14","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-044597","volume":"10","author":"A Pons-Rodriguez","year":"2020","unstructured":"Pons-Rodriguez A, Forn\u00e9 Izquierdo C, Vilaplana-Mayoral J, Cruz-Esteve I, S\u00e1nchez-L\u00f3pez I, Re\u00f1\u00e9-Re\u00f1\u00e9 M et al (2020) Feasibility and acceptability of personalised breast cancer screening (DECIDO study): protocol of a single-arm proof-of-concept trial. BMJ Open 10:e044597","journal-title":"BMJ Open"},{"key":"1797_CR15","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1007\/s10549-021-06346-w","volume":"189","author":"L Esserman","year":"2021","unstructured":"Esserman L, Eklund M, Veer LV, Shieh Y, Tice J, Ziv E et al (2021) The WISDOM study: a new approach to screening can and should be tested. Breast Cancer Res Treat 189:593\u2013598","journal-title":"Breast Cancer Res Treat"},{"key":"1797_CR16","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1186\/s12885-022-09484-6","volume":"22","author":"A Roux","year":"2022","unstructured":"Roux A, Cholerton R, Sicsic J, Moumjid N, French DP, Giorgi Rossi P et al (2022) Study protocol comparing the ethical, psychological and socio-economic impact of personalised breast cancer screening to that of standard screening in the \u201cMy Personal Breast Screening\u201d (MyPeBS) randomised clinical trial. BMC Cancer 22:507","journal-title":"BMC Cancer"},{"key":"1797_CR17","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1002\/sim.1668","volume":"23","author":"J Tyrer","year":"2004","unstructured":"Tyrer J, Duffy SW, Cuzick J (2004) A breast cancer prediction model incorporating familial and personal risk factors. Stat Med 23:1111\u20131130","journal-title":"Stat Med"},{"key":"1797_CR18","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1093\/jnci\/djy013","volume":"110","author":"MH Gail","year":"2018","unstructured":"Gail MH, Pfeiffer RM (2018) Breast cancer risk model requirements for counseling, prevention, and screening. J Natl Cancer Inst 110:994\u20131002","journal-title":"J Natl Cancer Inst"},{"key":"1797_CR19","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1038\/s41436-018-0406-9","volume":"21","author":"A Lee","year":"2019","unstructured":"Lee A, Mavaddat N, Wilcox AN, Cunningham AP, Carver T, Hartley S et al (2019) BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors. Genet Med 21:1708\u20131718","journal-title":"Genet Med"},{"key":"1797_CR20","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/s41416-021-01550-3","volume":"126","author":"AK Clift","year":"2022","unstructured":"Clift AK, Dodwell D, Lord S, Petrou S, Brady SM, Collins GS et al (2022) The current status of risk-stratified breast screening. Br J Cancer 126:533\u2013550","journal-title":"Br J Cancer"},{"key":"1797_CR21","doi-asserted-by":"publisher","DOI":"10.14694\/EdBook_AM.2013.33.e57","author":"NF Boyd","year":"2013","unstructured":"Boyd NF (2013) Mammographic density and risk of breast cancer. Am Soc Clin Oncol Educ Book. https:\/\/doi.org\/10.14694\/EdBook_AM.2013.33.e57","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"1797_CR22","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s10549-005-5152-4","volume":"94","author":"JA Tice","year":"2005","unstructured":"Tice JA, Cummings SR, Ziv E, Kerlikowske K (2005) Mammographic breast density and the Gail model for breast cancer risk prediction in a screening population. Breast Cancer Res Treat 94:115\u2013122","journal-title":"Breast Cancer Res Treat"},{"key":"1797_CR23","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s13058-015-0653-5","volume":"17","author":"AR Brentnall","year":"2015","unstructured":"Brentnall AR, Harkness EF, Astley SM, Donnelly LS, Stavrinos P, Sampson S et al (2015) Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort. Breast Cancer Res 17:147","journal-title":"Breast Cancer Res"},{"key":"1797_CR24","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1093\/jbi\/wbz006","volume":"1","author":"AR Brentnall","year":"2019","unstructured":"Brentnall AR, Cohn WF, Knaus WA, Yaffe MJ, Cuzick J, Harvey JA (2019) A case-control study to add volumetric or clinical mammographic density into the Tyrer-Cuzick breast cancer risk model. J Breast Imaging 1:99\u2013106","journal-title":"J Breast Imaging"},{"key":"1797_CR25","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s10549-016-4090-7","volume":"162","author":"JOP Wanders","year":"2017","unstructured":"Wanders JOP, Holland K, Veldhuis WB, Mann RM, Pijnappel RM, Peeters PHM et al (2017) Volumetric breast density affects performance of digital screening mammography. Breast Cancer Res Treat 162:95\u2013103","journal-title":"Breast Cancer Res Treat"},{"key":"1797_CR26","doi-asserted-by":"publisher","first-page":"268","DOI":"10.7326\/M15-1789","volume":"164","author":"J Melnikow","year":"2016","unstructured":"Melnikow J, Fenton JJ, Whitlock EP, Miglioretti DL, Weyrich MS, Thompson JH et al (2016) Supplemental screening for breast cancer in women with dense breasts: a systematic review for the U.S. preventive services task force. Ann Intern Med 164:268\u2013278","journal-title":"Ann Intern Med"},{"key":"1797_CR27","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1007\/s00330-018-5668-8","volume":"29","author":"A Vourtsis","year":"2019","unstructured":"Vourtsis A, Berg WA (2019) Breast density implications and supplemental screening. Eur Radiol 29:1762\u20131777","journal-title":"Eur Radiol"},{"key":"1797_CR28","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1056\/NEJMoa1903986","volume":"381","author":"MF Bakker","year":"2019","unstructured":"Bakker MF, de Lange SV, Pijnappel RM, Mann RM, Peeters PHM, Monninkhof EM et al (2019) Supplemental MRI screening for women with extremely dense breast tissue. N Engl J Med 381:2091\u20132102","journal-title":"N Engl J Med"},{"key":"1797_CR29","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s10549-021-06445-8","volume":"192","author":"M Saghatchian","year":"2022","unstructured":"Saghatchian M, Abehsera M, Yamgnane A, Geyl C, Gauthier E, H\u00e9lin V et al (2022) Feasibility of personalized screening and prevention recommendations in the general population through breast cancer risk assessment: results from a dedicated risk clinic. Breast Cancer Res Treat 192:375\u2013383","journal-title":"Breast Cancer Res Treat"},{"key":"1797_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0226352","volume":"14","author":"M Rom\u00e1n","year":"2019","unstructured":"Rom\u00e1n M, Sala M, Domingo L, Posso M, Louro J, Castells X (2019) Personalized breast cancer screening strategies: a systematic review and quality assessment. PLoS ONE 14:e0226352","journal-title":"PLoS ONE"},{"key":"1797_CR31","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/s41523-017-0035-5","volume":"3","author":"LJ Esserman","year":"2017","unstructured":"Esserman LJ, WISDOM Study and Athena Investigators (2017) The WISDOM Study: breaking the deadlock in the breast cancer screening debate. NPJ Breast Cancer 3:34","journal-title":"NPJ Breast Cancer"},{"key":"1797_CR32","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1177\/0272989X14528380","volume":"35","author":"JF O\u2019Mahony","year":"2015","unstructured":"O\u2019Mahony JF, van Rosmalen J, Mushkudiani NA, Goudsmit F-W, Eijkemans MJC, Heijnsdijk EAM et al (2015) The influence of disease risk on the optimal time interval between screens for the early detection of cancer: a mathematical approach. Med Decis Making 35:183\u2013195","journal-title":"Med Decis Making"},{"key":"1797_CR33","doi-asserted-by":"publisher","first-page":"700","DOI":"10.7326\/M16-0476","volume":"165","author":"A Trentham-Dietz","year":"2016","unstructured":"Trentham-Dietz A, Kerlikowske K, Stout NK, Miglioretti DL, Schechter CB, Ergun MA et al (2016) Tailoring breast cancer screening intervals by breast density and risk for women aged 50 years or older: collaborative modeling of screening outcomes. Ann Intern Med 165:700\u2013712","journal-title":"Ann Intern Med"},{"key":"1797_CR34","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1016\/j.jval.2017.04.012","volume":"20","author":"E Gray","year":"2017","unstructured":"Gray E, Donten A, Karssemeijer N, van Gils C, Evans DG, Astley S et al (2017) Evaluation of a stratified national breast screening program in the United Kingdom: an early model-based cost-effectiveness analysis. Value Health 20:1100\u20131119","journal-title":"Value Health"},{"key":"1797_CR35","doi-asserted-by":"publisher","first-page":"568","DOI":"10.2471\/BLT.18.207944","volume":"96","author":"L Sun","year":"2018","unstructured":"Sun L, Legood R, Sadique Z, Dos-Santos-Silva I, Yang L (2018) Cost-effectiveness of risk-based breast cancer screening programme, China. Bull World Health Organ 96:568\u2013577","journal-title":"Bull World Health Organ"},{"key":"1797_CR36","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.3390\/ijerph19031406","volume":"19","author":"C Laza-V\u00e1squez","year":"2022","unstructured":"Laza-V\u00e1squez C, Hern\u00e1ndez-Leal MJ, Carles-Lavila M, P\u00e9rez-Lacasta MJ, Cruz-Esteve I, Ru\u00e9 M et al (2022) Barriers and facilitators to the implementation of a personalized breast cancer screening program: views of Spanish health professionals. Int J Environ Res Public Health 19:1406","journal-title":"Int J Environ Res Public Health"},{"key":"1797_CR37","doi-asserted-by":"publisher","first-page":"5517","DOI":"10.1007\/s00330-019-06050-w","volume":"29","author":"L Bucchi","year":"2019","unstructured":"Bucchi L, Ravaioli A, Baldacchini F, Giuliani O, Mancini S, Vattiato R et al (2019) Annual mammography at age 45\u201349 years and biennial mammography at age 50\u201369 years: comparing performance measures in an organised screening setting. Eur Radiol 29:5517\u20135527","journal-title":"Eur Radiol"},{"key":"1797_CR38","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1177\/0969141320946059","volume":"28","author":"L Bucchi","year":"2021","unstructured":"Bucchi L, Ravaioli A, Baldacchini F, Giuliani O, Mancini S, Vattiato R et al (2021) Incidence of interval breast cancer among women aged 45\u201349 in an organised mammography screening setting. J Med Screen 28:207\u2013209","journal-title":"J Med Screen"},{"key":"1797_CR39","unstructured":"Cancer Research UK (2015) Breast cancer incidence (invasive) statistics. https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/breast-cancer\/incidence-invasive. Accessed 15 Mar 2023."},{"key":"1797_CR40","unstructured":"National Cancer Institute (2023) SEER*Explorer Application. https:\/\/seer.cancer.gov\/statistics-network\/explorer\/application.html?site=55&data_type=1&graph_type=2&compareBy=age_range&chk_age_range_1=1&chk_age_range_9=9&chk_age_range_141=141&chk_age_range_157=157&rate_type=2&sex=3&race=1&stage=101&advopt_precision=1&advopt_show_ci=on&hdn_view=0&advopt_show_apc=on&advopt_display=2. Accessed 15 Mar 2023."},{"key":"1797_CR41","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1146\/annurev-publhealth-040617-014128","volume":"39","author":"MA Handley","year":"2018","unstructured":"Handley MA, Lyles CR, McCulloch C, Cattamanchi A (2018) Selecting and improving quasi-experimental designs in effectiveness and implementation research. Annu Rev Public Health 39:5\u201325","journal-title":"Annu Rev Public Health"},{"key":"1797_CR42","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1002\/cncr.22671","volume":"109","author":"Swedish Organised Service Screening Evaluation Group","year":"2007","unstructured":"Swedish Organised Service Screening Evaluation Group (2007) Effect of mammographic service screening on stage at presentation of breast cancers in Sweden. Cancer 109:2205\u20132212","journal-title":"Cancer"},{"key":"1797_CR43","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1038\/bjc.2016.8","volume":"114","author":"ML Lousdal","year":"2016","unstructured":"Lousdal ML, Kristiansen IS, M\u00f8ller B, St\u00f8vring H (2016) Effect of organised mammography screening on stage-specific incidence in Norway: population study. Br J Cancer 114:590\u2013596","journal-title":"Br J Cancer"},{"key":"1797_CR44","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1002\/cncr.28014","volume":"119","author":"F Foca","year":"2013","unstructured":"Foca F, Mancini S, Bucchi L, Puliti D, Zappa M, Naldoni C et al (2013) Decreasing incidence of late-stage breast cancer after the introduction of organized mammography screening in Italy. Cancer 119:2022\u20132028","journal-title":"Cancer"},{"key":"1797_CR45","doi-asserted-by":"publisher","first-page":"5881","DOI":"10.1088\/0031-9155\/52\/19\/010","volume":"52","author":"R Highnam","year":"2007","unstructured":"Highnam R, Jeffreys M, McCormack V, Warren R, Davey Smith G, Brady M (2007) Comparing measurements of breast density. Phys Med Biol 52:5881\u20135895","journal-title":"Phys Med Biol"},{"key":"1797_CR46","first-page":"38","volume":"41","author":"P Sassoli de Bianchi","year":"2017","unstructured":"Sassoli de Bianchi P, Ravaioli A, Ferretti S, Finarelli AC, Giannini A, Naldoni C et al (2017) Extension of the target age range of mammography screening programme and governance of mammography practice in the Emilia-Romagna Region (Northern Italy). Epidemiol Prev 41:38\u201345","journal-title":"Epidemiol Prev"},{"key":"1797_CR47","volume-title":"International statistical classification of diseases and related health problems","author":"World Health Organization","year":"2015","unstructured":"World Health Organization (2015) International statistical classification of diseases and related health problems. World Health Organization, Geneva"},{"key":"1797_CR48","first-page":"244","volume":"58","author":"F Battisti","year":"2022","unstructured":"Battisti F, Mantellini P, Falini P, Ventura L, Giordano L, Saguatti G et al (2022) Key performance indicators of breast cancer screening programmes in Italy, 2011\u20132019. Ann Ist Super Sanita 58:244\u2013253","journal-title":"Ann Ist Super Sanita"},{"key":"1797_CR49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0279415","volume":"17","author":"S Guzzinati","year":"2022","unstructured":"Guzzinati S, Battagello J, Bovo E, Baracco M, Baracco S, Carpin E et al (2022) Quality control on digital cancer registration. PLoS ONE 17:e0279415","journal-title":"PLoS ONE"},{"key":"1797_CR50","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1258\/jms.2008.007016","volume":"15","author":"L Bucchi","year":"2008","unstructured":"Bucchi L, Ravaioli A, Foca F, Colamartini A, Falcini F, Naldoni C et al (2008) Incidence of interval breast cancers after 650,000 negative mammographies in 13 Italian health districts. J Med Screen 15:30\u201335","journal-title":"J Med Screen"},{"key":"1797_CR51","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.ejca.2016.12.030","volume":"75","author":"D Puliti","year":"2017","unstructured":"Puliti D, Bucchi L, Mancini S, Paci E, Baracco S, Campari C et al (2017) Advanced breast cancer rates in the epoch of service screening: the 400,000 women cohort study from Italy. Eur J Cancer 75:109\u2013116","journal-title":"Eur J Cancer"},{"key":"1797_CR52","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1016\/j.cgh.2022.01.053","volume":"20","author":"F Baldacchini","year":"2022","unstructured":"Baldacchini F, Bucchi L, Giuliani O, Mancini S, Ravaioli A, Vattiato R et al (2022) Effects of attendance to an organized fecal immunochemical test screening program on the risk of colorectal cancer: an observational cohort study. Clin Gastroenterol Hepatol 20:2373\u20132382","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["La radiologia medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-024-01797-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11547-024-01797-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11547-024-01797-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T11:04:28Z","timestamp":1715425468000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11547-024-01797-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,21]]},"references-count":52,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5]]}},"alternative-id":["1797"],"URL":"https:\/\/doi.org\/10.1007\/s11547-024-01797-9","relation":{},"ISSN":["1826-6983"],"issn-type":[{"value":"1826-6983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,21]]},"assertion":[{"value":"15 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"FR is the Director of the Regional Prevention Department which provided partial funding.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The RIBBS study is conducted in accordance with the principles of ethics as stated in the Declaration of Helsinki, and the relevant provisions of Good Clinical Practices defined by the International Conference on Harmonisation. The study was approved by the Institutional Ethics Committee of the Veneto Institute of Oncology (IOV) IRCCS, Padua, Italy in May 2019 under code \u201cRIBBS 2019\/37\u201d.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}