{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:33Z","timestamp":1761177633413,"version":"build-2065373602"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Renal transplant biopsy remains the gold standard for etiological diagnosis of graft dysfunction and subsequent management. When percutaneous renal biopsy (PRB) is contraindicated due to bleeding risk or limited percutaneous access, the fluoroscopy-guided transvenous femoral renal transplant biopsy (TFRB) might be a valuable alternative. This study aims to describe the TFRB technique, its safety, and efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients who underwent TFRB at our institution between 2020 and 2023 were retrospectively analyzed. Procedure outcomes, patients\u2019 characteristics and follow-up data were collected. Adverse events were graded using the Adverse Events Classification of the Society of Interventional Radiology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From January 2020 to December 2023, 109 patients (median age 61.2\u00a0years (Interquartile range (IQR), 54.5\u201368.6) ; 49 males (45.0%)) underwent 122 TFRB. Transvenous approach was indicated due to high bleeding risk in 61.5% (75\/122), limited percutaneous access in 13.9% (17\/122), or previous failed PRB in 2.5% (3\/122). Biopsy success rate was 94.3%, with 7 graft vein catheterization failures. Adequate Banff 97 criteria specimens were obtained in 68.7% of cases, and a definitive histological diagnosis was achieved in 96.5% of biopsies. Complications occurred in 20.0% of procedures (23\/115), including 9 major complications (7.8%), with no significant difference according to the TFRB indication (bleeding risk versus percutaneous limited access) (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.70), use of antiplatelet agents (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.24) or anticoagulants (\n                      <jats:italic>p<\/jats:italic>\n                      = 1.00).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the first large cohort study to demonstrates TFRB to be effective and safe in case of contraindication to PRB, providing valuable insights for graft dysfunction management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphic abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s11547-025-02045-4","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T15:11:00Z","timestamp":1754147460000},"page":"1711-1721","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fluoroscopy-guided transvenous femoral renal transplant biopsies: a monocentric retrospective study about 109 consecutive patients"],"prefix":"10.1007","volume":"130","author":[{"given":"Farha","family":"Tessier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Roux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Brocheriou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"Barrou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marine","family":"Bravetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathilde","family":"A\u00efssaoui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Charles","family":"Bijot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloi","family":"Varin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9rome","family":"Tourret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne","family":"Fran\u00e7ois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Drouin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1238-9167","authenticated-orcid":false,"given":"Louis","family":"Meyblum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"2045_CR1","doi-asserted-by":"publisher","first-page":"2988","DOI":"10.1093\/ndt\/gfq780","volume":"26","author":"M Haller","year":"2011","unstructured":"Haller M, Gutjahr G, Kramar R, Harnoncourt F, Oberbauer R (2011) Cost-effectiveness analysis of renal replacement therapy in Austria. 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Approval was granted by the Medical Imaging Research Ethics Committee (February 22, 2024\/CRM-2401-389). Fluoroscopy-guided transvenous biopsy is a valuable technique to obtaining a histological diagnosis on renal transplants when percutaneous renal biopsy is contraindicated and is safe despite the high bleeding risk in this patient population.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from each patient in accordance with the policy of our institution regarding chart reviews","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that human research participants provided informed consent for publication.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publication"}}]}}