{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T02:30:46Z","timestamp":1794537046488,"version":"4.9.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess the accuracy and safety of CT-guided percutaneous core-needle biopsies of pancreatic lesions suspected to be malignant based on MRI or CT scans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed CT-guided percutaneous biopsies of suspicious pancreatic lesions performed at our university hospital. Biopsy was performed using a 17G coaxial needle and an 18G core biopsy needle. Data on patient characteristics, lesions, procedures, and histologic results were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 90 patients (58.9% males, mean age 65\u2009\u00b1\u200912.2\u00a0years) underwent CT-guided percutaneous biopsies. The lesions had a mean size of 36.8\u2009\u00b1\u200912.2\u00a0mm and were predominantly located in the pancreatic head 61.1% (55\/90). Technical success was achieved in all biopsies 100% (90\/90). Most procedures 96.7% (87\/90) were performed using direct access routes, while 3.3% (3\/90) required indirect transhepatic or transgastric approaches. Among the biopsies, 65.6% (59\/90) confirmed malignancy, with adenocarcinoma as the most common malignant subtype representing 55.6% (50\/90) of all cases. The rate of non-malignant findings was 26.7% (24\/90) including chronic pancreatitis at a rate of 5.6% (5\/90) as well as pancreatic pseudocysts and pancreatic cystadenoma each at a rate of 2.2% (2\/90), among others. A total of seven cases were identified as false negatives confirmed, but malignancy was later confirmed after re-biopsy or surgery. The initial diagnostic accuracy was 92.2% (83\/90). The rate of major complications was 1.1% (1\/90), and a total of two minor complications\u00a0at a rate of 2.2%\u00a0were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study shows that CT-guided pancreatic biopsy is a safe procedure with high diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11547-025-02087-8","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T04:59:09Z","timestamp":1758257949000},"page":"1903-1908","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Accuracy and safety of percutaneous CT-guided pancreatic biopsies"],"prefix":"10.1007","volume":"130","author":[{"given":"Thomas J.","family":"Vogl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4142-3398","authenticated-orcid":false,"given":"Hamzah","family":"Adwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonhard","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahem","family":"Al Haj Ibrahem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"key":"2087_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 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