{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:39:36Z","timestamp":1792694376629,"version":"4.5.0"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiol med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Over the past four decades, the management of thyroid nodules and selected thyroid malignancies has progressively shifted from surgery-centered approaches toward image-guided minimally invasive treatments (MITT). What began in 1985 with ultrasound-guided percutaneous ethanol injection evolved into a range of energy-based techniques, including laser ablation (LA), radiofrequency ablation (RFA), microwave ablation (MWA), and high-intensity focused ultrasound (HIFU).<\/jats:p>\n                  <jats:p>This historical review aimed to reconstruct the major milestones in the development of image-guided thyroid ablation. A systematic PubMed literature search and predefined selection criteria were used to identify seminal studies, first clinical applications, major technological innovations, comparative studies, guideline-defining publications, and landmark long-term follow-up studies. Overall, 43 milestone papers were included for qualitative historical analysis. The evolution of thyroid ablation can be divided into five phases: conceptual origins (1985\u20131999), birth of the thermal procedures\u2019 era (2000\u20132006), methodological standardization (2007\u20132012), oncologic consolidation and comparative evidence (2013\u20132018), and final codification by means of international guideline endorsement and long-term validation (2019\u20132025). Recent 10-year follow-up studies have confirmed the durable efficacy of MITT for benign nodule management and their sustained oncologic control in low-risk papillary thyroid microcarcinoma. Image-guided thyroid ablation has transitioned from experimental innovation to an evidence-based, guideline-supported therapeutic domain, representing a paradigm shift toward precision medicine, organ preservation, and minimally invasive endocrine oncology.<\/jats:p>","DOI":"10.1007\/s11547-026-02296-9","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:45:35Z","timestamp":1792647935000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The evolution of image-guided ablations for thyroid disorders: a historical review"],"prefix":"10.1007","author":[{"given":"Giovanni","family":"Mauri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2005-4432","authenticated-orcid":false,"given":"Eleonora","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Papini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Solbiati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Spiezia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hwan","family":"Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca Maria","family":"Sconfienza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"2296_CR1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.575152","volume":"11","author":"G Mauri","year":"2021","unstructured":"Mauri G, Orsi F, Carriero S, Della Vigna P, De Fiori E, Monzani D et al (2021) Image-guided thermal ablation as an alternative to surgery for papillary thyroid microcarcinoma: preliminary results of an Italian experience. Front Endocrinol (Lausanne) 11:575152. https:\/\/doi.org\/10.3389\/fendo.2020.575152","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2296_CR2","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2016.1262969","author":"G Mauri","year":"2017","unstructured":"Mauri G, Sconfienza LM (2017) Image-guided thermal ablation might be a way to compensate for image deriving cancer overdiagnosis. Int J Hyperthermia 33:489\u2013490. https:\/\/doi.org\/10.1080\/02656736.2016.1262969","journal-title":"Int J Hyperthermia"},{"key":"2296_CR3","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1016\/j.jvir.2014.08.027","volume":"25","author":"M Ahmed","year":"2014","unstructured":"Ahmed M, Solbiati L, Brace CL, Breen DJ, Callstrom MR, Charboneau JW et al (2014) Image-guided tumor ablation: standardization of terminology and reporting criteria\u2014a 10-year update. 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