{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:11:48Z","timestamp":1791223908861,"version":"4.1.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010659","name":"Erasmus Universitair Medisch Centrum Rotterdam","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J CARS"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>In minimally invasive spring-assisted craniectomy, surgeons plan the surgery by manually locating the cranial sutures. However, this approach is prone to error. Augmented reality (AR) could be used to visualize the cranial sutures and assist in the surgery planning. The purpose of our work is to develop an AR-based system to visualize cranial sutures, and to assess the accuracy and usability of using AR-based navigation for surgical guidance in minimally invasive spring-assisted craniectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An AR system was developed that consists of an electromagnetic tracking system linked with a Microsoft HoloLens. The system was used to conduct a study with two skull phantoms. For each phantom, five sutures were annotated and visualized on the skull surface. Twelve participants assessed the system. For each participant, model alignment using six anatomical landmarks was performed, followed by the participant delineation of the visualized sutures. At the end, the participants filled a system usability scale (SUS) questionnaire. For evaluation, an independent optical tracking system was used and the delineated sutures were digitized and compared to the CT-annotated sutures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      For a total of 120 delineated sutures, the distance of the annotated sutures to the planning reference was\n                      <jats:inline-formula>\n                        <jats:alternatives>\n                          <jats:tex-math>$$2.4\\pm 1.2$$<\/jats:tex-math>\n                          <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                            <mml:mrow>\n                              <mml:mn>2.4<\/mml:mn>\n                              <mml:mo>\u00b1<\/mml:mo>\n                              <mml:mn>1.2<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:math>\n                        <\/jats:alternatives>\n                      <\/jats:inline-formula>\n                      \u00a0mm. The average delineation time per suture was\n                      <jats:inline-formula>\n                        <jats:alternatives>\n                          <jats:tex-math>$$13\\pm 5$$<\/jats:tex-math>\n                          <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                            <mml:mrow>\n                              <mml:mn>13<\/mml:mn>\n                              <mml:mo>\u00b1<\/mml:mo>\n                              <mml:mn>5<\/mml:mn>\n                            <\/mml:mrow>\n                          <\/mml:math>\n                        <\/jats:alternatives>\n                      <\/jats:inline-formula>\n                      \u00a0s. For the system usability questionnaire, an average SUS score of 73 was obtained.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The developed AR-system has good accuracy (average 2.4\u00a0mm distance) and could be used in the OR. The system can assist in the pre-planning of minimally invasive craniosynostosis surgeries to locate cranial sutures accurately instead of the traditional approach of manual palpation. Although the conducted phantom study was designed to closely reflect the clinical setup in the OR, further clinical validation of the developed system is needed and will be addressed in a future work.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11548-022-02634-y","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T05:03:01Z","timestamp":1651640581000},"page":"1453-1460","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Augmented reality navigation for minimally invasive craniosynostosis surgery: a phantom study"],"prefix":"10.1007","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0505-2198","authenticated-orcid":false,"given":"Abdullah","family":"Thabit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Benmahdjoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Lise C.","family":"van Veelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiro J.","family":"Niessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eppo B.","family":"Wolvius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8257-7759","authenticated-orcid":false,"given":"Theo","family":"van Walsum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,4]]},"reference":[{"issue":"4","key":"2634_CR1","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/ejhg.2010.235","volume":"19","author":"D Johnson","year":"2011","unstructured":"Johnson D, Wilkie AO (2011) Craniosynostosis. Eur J Hum Genet 19(4):369\u2013376","journal-title":"Eur J Hum Genet"},{"issue":"9","key":"2634_CR2","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1016\/j.jcms.2016.07.007","volume":"44","author":"M Cornelissen","year":"2016","unstructured":"Cornelissen M, den Ottelander B, Rizopoulos D, van der Hulst R, van der Molen AM, van der Horst C, Delye H, van Veelen M-L, Bonsel G, Mathijssen I (2016) Increase of prevalence of craniosynostosis. J Cranio-Maxillofac Surg 44(9):1273\u20131279","journal-title":"J Cranio-Maxillofac Surg"},{"issue":"5","key":"2634_CR3","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.pediatrneurol.2015.07.006","volume":"53","author":"LS Governale","year":"2015","unstructured":"Governale LS (2015) Craniosynostosis. Pediatr Neurol 53(5):394\u2013401","journal-title":"Pediatr Neurol"},{"issue":"9","key":"2634_CR4","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.1007\/s00381-012-1850-5","volume":"28","author":"M-LC van Veelen","year":"2012","unstructured":"van Veelen M-LC, Mathijssen IM (2012) Spring-assisted correction of sagittal suture synostosis. Childs Nerv Syst 28(9):1347\u20131351","journal-title":"Childs Nerv Syst"},{"key":"2634_CR5","doi-asserted-by":"crossref","unstructured":"V\u00e1vra P, Roman J, Zon\u010da P, Ihn\u00e1t P, N\u011bmec M, Kumar J, Habib N, El-Gendi A (2017) Recent development of augmented reality in surgery: a review. J Healthc Eng 2017","DOI":"10.1155\/2017\/4574172"},{"issue":"4","key":"2634_CR6","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1080\/21681163.2020.1834876","volume":"9","author":"D Garc\u00eda-Mato","year":"2021","unstructured":"Garc\u00eda-Mato D, Moreta-Mart\u00ednez R, Garc\u00eda-Sevilla M, Ochandiano S, Garc\u00eda-Leal R, P\u00e9rez-Ma\u00f1anes R, Calvo-Haro JA, Salmer\u00f3n JI, Pascau J (2021) Augmented reality visualization for craniosynostosis surgery. Comput Methods Biomech Biomed Eng Imaging Vis 9(4):392\u2013399","journal-title":"Comput Methods Biomech Biomed Eng Imaging Vis"},{"key":"2634_CR7","doi-asserted-by":"crossref","unstructured":"Alshomer F, Alazzam A, Alturki A, Almeshal O, Alhusainan H (2021) Smartphone-assisted augmented reality in craniofacial surgery. Plast Reconstr Surg Global Open 9(8)","DOI":"10.1097\/GOX.0000000000003743"},{"issue":"8","key":"2634_CR8","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1016\/j.jcms.2019.04.008","volume":"47","author":"W Han","year":"2019","unstructured":"Han W, Yang X, Wu S, Fan S, Chen X, Aung ZM, Liu T, Zhang Y, Gu S, Chai G (2019) A new method for cranial vault reconstruction: augmented reality in synostotic plagiocephaly surgery. J Cranio-Maxillofac Surg 47(8):1280\u20131284","journal-title":"J Cranio-Maxillofac Surg"},{"issue":"4","key":"2634_CR9","doi-asserted-by":"publisher","first-page":"1914","DOI":"10.1002\/rcs.1914","volume":"14","author":"JW Yoon","year":"2018","unstructured":"Yoon JW, Chen RE, Kim EJ, Akinduro OO, Kerezoudis P, Han PK, Si P, Freeman WD, Diaz RJ, Komotar RJ, Pirris SM, Brown BL, Bydon M, Wang MY, Wharen RE Jr, Quinones-Hinojosa A (2018) Augmented reality for the surgeon: systematic review. Int J Med Robot Comput Assist Surg 14(4):1914","journal-title":"Int J Med Robot Comput Assist Surg"},{"key":"2634_CR10","unstructured":"Brooke J (1996) Sus: a quick and dirty usability. Usability Eval Ind 189(3)"},{"issue":"11","key":"2634_CR11","doi-asserted-by":"publisher","first-page":"4332","DOI":"10.1109\/TVCG.2021.3106506","volume":"27","author":"M Benmahdjoub","year":"2021","unstructured":"Benmahdjoub M, Niessen WJ, Wolvius EB, Van Walsum T (2021) Virtual extensions improve perception-based instrument alignment using optical see-through devices. IEEE Trans Vis Comput Graph 27(11):4332\u20134341","journal-title":"IEEE Trans Vis Comput Graph"}],"container-title":["International Journal of Computer Assisted Radiology and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11548-022-02634-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11548-022-02634-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11548-022-02634-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T23:40:45Z","timestamp":1658533245000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11548-022-02634-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,4]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["2634"],"URL":"https:\/\/doi.org\/10.1007\/s11548-022-02634-y","relation":{},"ISSN":["1861-6429"],"issn-type":[{"value":"1861-6429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,4]]},"assertion":[{"value":"22 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No ethical approval is required for this study as no patient data were used.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}