{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:49:04Z","timestamp":1777661344809,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T00:00:00Z","timestamp":1283904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hand (New York, N,Y.)"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>\n                    Hand-arm vibration syndrome (HAVS) is a debilitating sequela of neurological and vascular injuries caused by prolonged occupational exposure to hand-transmitted vibration. Our previous study demonstrated that short-term exposure to vibration can induce vasoconstriction and endothelial cell damage in the ventral artery of the rat's tail. The present study investigated whether pretreatment with D-4F, an apolipoprotein A-1 mimetic with known anti-oxidant and vasodilatory properties, prevents vibration-induced vasoconstriction, endothelial cell injury, and protein nitration. Rats were injected intraperitoneally with 3 mg\/kg D-4F at 1 h before vibration of the tails for 4 h\/day at 60 Hz, 49 m\/s\n                    <jats:sup>2<\/jats:sup>\n                    r.m.s. acceleration for either 1 or 3 days. Vibration-induced endothelial cell damage was examined by light microscopy and nitrotyrosine immunoreactivity (a marker for free radical production). One and 3-day vibration produced vasoconstriction and increased nitrotyrosine. Preemptive treatment with D-4F prevented these negative changes. These findings suggest that D-4F may be useful in the prevention of HAVS.\n                  <\/jats:p>","DOI":"10.1007\/s11552-010-9289-1","type":"journal-article","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T12:08:12Z","timestamp":1283861292000},"page":"64-70","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["The Preventive Effects of Apolipoprotein Mimetic D-4F from Vibration Injury\u2014Experiment in Rats"],"prefix":"10.1177","volume":"6","author":[{"given":"David J.","family":"Rowe","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, University Hospitals Case Medical Center, 29001 Cedar Road, Lyndhurst, OH 44124, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Geng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin 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