{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:11:52Z","timestamp":1765354312192},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Huazhong Univ. Sci. Technol. [Med. Sci.]"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1007\/s11596-012-0096-5","type":"journal-article","created":{"date-parts":[[2012,8,10]],"date-time":"2012-08-10T16:45:09Z","timestamp":1344617109000},"page":"557-562","source":"Crossref","is-referenced-by-count":4,"title":["Effect of second-generation antiepileptic drugs on diplopia: A meta-analysis of placebo-controlled studies"],"prefix":"10.1007","volume":"32","author":[{"given":"Haiyan","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wensheng","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huicong","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guohua","family":"Zhen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suiqiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,8,11]]},"reference":[{"key":"96_CR1","volume-title":"Adams and Victor\u2019s principles of neurology","author":"A.H. Ropper","year":"2005","unstructured":"Ropper AH, Brown RH. Adams and Victor\u2019s principles of neurology. McGraw-Hill Publishing, New York, 2005."},{"issue":"12","key":"96_CR2","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/j.1499-1654.2000.001597.x","volume":"41","author":"G. Barcs","year":"2000","unstructured":"Barcs G, Walker EB, Elger CE, et al. Oxcarbazepine placebo-controlled, dose-ranging trial in refractory partial epilepsy. Epilepsia, 2000,41(12):1597\u20131607","journal-title":"Epilepsia"},{"issue":"3","key":"96_CR3","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0920-1211(89)90007-7","volume":"4","author":"C.D. Binnie","year":"1989","unstructured":"Binnie CD, Debets RMC, Engelsman M, et al. Double-blind crossover trial of lamotrigine (Lamictal) as add-on therapy in intractable epilepsy. Epilepsy Res, 1989,4(3):222\u2013229","journal-title":"Epilepsy Res"},{"issue":"11","key":"96_CR4","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1212\/WNL.43.11.2284","volume":"43","author":"F. Matsuo","year":"1993","unstructured":"Matsuo F, Bergen D, Faught E, et al. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures. U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. Neurology, 1993,43(11):2284\u20132291","journal-title":"Neurology"},{"issue":"5","key":"96_CR5","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1136\/jnnp.56.5.448","volume":"56","author":"G.J. Schapel","year":"1993","unstructured":"Schapel GJ, Beran RG, Vajda FJ, et al. Double-blind, placebo controlled, crossover study of lamotrigine in treatment of resistant partial seizures. J Neurol Neurosurg Psychiatry, 1993,56(5):448\u2013453","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"96_CR6","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1528-1157.1993.tb02417.x","volume":"34","author":"D. Smith","year":"1993","unstructured":"Smith D, Baker G, Davies G, et al. Outcomes of add-on treatment with lamotrigine in partial epilepsy. Epilepsia, 1993,34(2):312\u2013322","journal-title":"Epilepsia"},{"issue":"1","key":"96_CR7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1528-1157.1994.tb02920.x","volume":"35","author":"J. Messenheimer","year":"1994","unstructured":"Messenheimer J, Ramsay RE, Willmore LJ, et al. Lamotrigine therapy for partial seizures: a multicenter, placebo-controlled, double-blind, cross-over trial. Epilepsia, 1994,35(1):113\u2013121","journal-title":"Epilepsia"},{"issue":"3","key":"96_CR8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0896-6974(95)00034-B","volume":"8","author":"S.C. Schachter","year":"1995","unstructured":"Schachter SC, Leppik IE, Matsuo F, et al. Lamotrigine: a six-month, placebo-controlled, safety and tolerance study. J Epilepsy, 1995,8(3):201\u2013209","journal-title":"J Epilepsy"},{"issue":"6","key":"96_CR9","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1212\/WNL.46.6.1684","volume":"46","author":"E. Faught","year":"1996","unstructured":"Faught E, Wilder BJ, Ramsay RE, et al. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, 600-mg daily dosages. Neurology, 1996,46(6):1684\u20131690","journal-title":"Neurology"},{"issue":"6","key":"96_CR10","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1212\/WNL.46.6.1678","volume":"46","author":"M. Privitera","year":"1996","unstructured":"Privitera M, Fincham R, Penry J, et al. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, 1000-mg daily dosages. Neurology, 1996,46(6):1678\u20131683","journal-title":"Neurology"},{"issue":"11","key":"96_CR11","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1212\/WNL.43.11.2292","volume":"43","author":"The US Gabapentin Study Group No. 5.","year":"1993","unstructured":"The US Gabapentin Study Group No. 5. Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. Neurology, 1993,43(11):2292\u20132298","journal-title":"Neurology"},{"issue":"4","key":"96_CR12","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1528-1157.1994.tb02513.x","volume":"35","author":"H. Anhut","year":"1994","unstructured":"Anhut H, Ashman P, Feuerstein TJ, et al. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: a double-blind, placebo-controlled study. Epilepsia, 1994,35(4):795\u2013801","journal-title":"Epilepsia"},{"issue":"4","key":"96_CR13","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1440-1819.2006.01553.x","volume":"60","author":"T. Yamauchi","year":"2006","unstructured":"Yamauchi T, Kaneko S, Yagi K, et al. Treatment of partial seizures with gabapentin: double-blind, placebo-controlled, parallel-group study. Psychiatry Clin Neurosci, 2006,60(4):507\u2013515","journal-title":"Psychiatry Clin Neurosci"},{"issue":"1","key":"96_CR14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.0013-9580.2004.31203.x","volume":"45","author":"S. Arroyo","year":"2004","unstructured":"Arroyo S, Anhut H, Kugler AR, et al. Pregabalin add-on treatment: a randomized, double-blind, placebo-controlled, dose-response study in adults with partial seizures. Epilepsia, 2004,45(1):20\u201327","journal-title":"Epilepsia"},{"issue":"3","key":"96_CR15","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1212\/01.WNL.0000150932.48688.BE","volume":"64","author":"A. Beydoun","year":"2005","unstructured":"Beydoun A, Uthman BM, Kugler AR, et al. Safety and efficacy of two pregabalin regimens for add-on treatment of partial epilepsy. Neurology, 2005,64(3):475\u2013480","journal-title":"Neurology"},{"issue":"12","key":"96_CR16","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1111\/j.1528-1167.2005.00341.x","volume":"46","author":"C.E. Elger","year":"2005","unstructured":"Elger CE, Brodie MJ, Anhut H, et al. Pregabalin add-on treatment in patients with partial seizures: a novel evaluation of flexible-dose and fixed-dose treatment in a double-blind, placebo-controlled study. Epilepsia, 2005,46(12):1926\u20131936","journal-title":"Epilepsia"},{"issue":"4","key":"96_CR17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S1059-1311(96)80018-5","volume":"5","author":"R.G. Beran","year":"1996","unstructured":"Beran RG, Berkovic SF, Buchanan N, et al. A double-blind, placebo-controlled crossover study of vigabatrin 2 g\/day and 3 g\/day in uncontrolled partial seizures. Seizure, 1996,5(4):259\u2013265","journal-title":"Seizure"},{"issue":"3","key":"96_CR18","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1053\/seiz.2000.0381","volume":"9","author":"J. Bruni","year":"2000","unstructured":"Bruni J, Guberman A, Vachon L, et al. Vigabatrin as add-on therapy for adult complex partial seizures: a double-blind, placebo-controlled multicentre study. Seizure, 2000,9(3):224\u2013232","journal-title":"Seizure"},{"issue":"1","key":"96_CR19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1528-1167.2006.00372.x","volume":"47","author":"J.J. Tsai","year":"2006","unstructured":"Tsai JJ, Yen DJ, Hsih MS, et al. Efficacy and safety of levetiracetam (up to 2000 mg\/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled study. Epilepsia, 2006,47(1):72\u201381","journal-title":"Epilepsia"},{"issue":"2\u20133","key":"96_CR20","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.eplepsyres.2007.04.007","volume":"75","author":"M. Baulac","year":"2007","unstructured":"Baulac M, Leppik IE. Efficacy and safety of adjunctive zonisamide therapy for refractory partial seizures. Epilepsy Res, 2007,75(2\u20133):75\u201383","journal-title":"Epilepsy Res"},{"key":"96_CR21","volume-title":"General principle: how to use antiepileptic drugs","author":"R.J. Porter","year":"1989","unstructured":"Porter RJ. General principle: how to use antiepileptic drugs. Raven Press, New York, 1989."},{"issue":"1","key":"96_CR22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1528-1157.1981.tb04327.x","volume":"22","author":"E.H. Reynolds","year":"1981","unstructured":"Reynolds EH, Shorvon SD. Monotherapy or polytherapy for epilepsy? Epilepsia, 1981,22(1):1\u201310","journal-title":"Epilepsia"}],"container-title":["Journal of Huazhong University of Science and Technology [Medical Sciences]"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-012-0096-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11596-012-0096-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-012-0096-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T13:15:13Z","timestamp":1559394913000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11596-012-0096-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["96"],"URL":"https:\/\/doi.org\/10.1007\/s11596-012-0096-5","relation":{},"ISSN":["1672-0733","1993-1352"],"issn-type":[{"value":"1672-0733","type":"print"},{"value":"1993-1352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}