{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T08:21:28Z","timestamp":1782980488738,"version":"3.54.5"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Huazhong Univ. Sci. Technol. [Med. Sci.]"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1007\/s11596-013-1190-z","type":"journal-article","created":{"date-parts":[[2013,10,19]],"date-time":"2013-10-19T12:48:10Z","timestamp":1382186890000},"page":"743-747","source":"Crossref","is-referenced-by-count":12,"title":["Clinical efficacy and safety of chelation treatment with typical penicillamine in cross combination with DMPS repeatedly for Wilson\u2019s disease"],"prefix":"10.1007","volume":"33","author":[{"given":"San-qing","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-fang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-yun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,10,20]]},"reference":[{"issue":"9559","key":"1190_CR1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0140-6736(07)60196-2","volume":"369","author":"A Ala","year":"2007","unstructured":"Ala A, Walker AP, Ashkan K, et al. Wilson\u2019s disease. Lancet, 2007,369(9559):397\u2013408","journal-title":"Lancet"},{"issue":"3","key":"1190_CR2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1517\/14656566.7.3.317","volume":"7","author":"GJ Brewer","year":"2006","unstructured":"Brewer GJ. Novel therapeutic approaches to the treatment of Wilson\u2019s disease. Expert Opin Pharmacother, 2006,7(3):317\u2013324","journal-title":"Expert Opin Pharmacother"},{"issue":"5","key":"1190_CR3","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1001\/archneur.1987.00520170020016","volume":"44","author":"GJ Brewer","year":"1987","unstructured":"Brewer GJ, Terry CA, Aisen AM, et al. Worsening of neurologic syndrome in patients with Wilson\u2019s disease with initial penicillamine therapy. Arch Neurol, 1987,44(5):490\u2013493","journal-title":"Arch Neurol"},{"issue":"4","key":"1190_CR4","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s11910-002-0007-4","volume":"2","author":"I Subramanian","year":"2002","unstructured":"Subramanian I, Vanek ZF, Bronstein JM. Diagnosis and treatment of Wilson\u2019s disease. Curr Neurol Neurosci Rep, 2002,2(4):317\u2013323","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"5","key":"1190_CR5","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1002\/hep.23182","volume":"50","author":"F Linn","year":"2009","unstructured":"Linn F, Houwen R, van Hattum J, et al. Long-term exclusive zinc monotherapy in symptomatic Wilson disease: experience in 17 patients. Hepatology, 2009,50(5):1442\u20131452","journal-title":"Hepatology"},{"key":"1190_CR6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3184\/003685013X13587771579987","volume":"96Pt1","author":"R Purchase","year":"2013","unstructured":"Purchase R. The treatment of Wilson\u2019s disease, a rare genetic disorder of copper metabolism. Sci Prog, 2013,96 (Pt 1):19\u201332","journal-title":"Sci Prog"},{"issue":"1-2","key":"1190_CR7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jns.2007.08.006","volume":"264","author":"S Sinha","year":"2008","unstructured":"Sinha S, Taly AB. Withdrawal of penicillamine from zinc sulphate-penicillamine maintenance therapy in Wilson\u2019s disease: promising, safe and cheap. J Neurol Sci, 2008,264(1-2): 129\u2013132","journal-title":"J Neurol Sci"},{"issue":"1","key":"1190_CR8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1365-2710.2007.00794.x","volume":"32","author":"CC Ping","year":"2007","unstructured":"Ping CC, Hassan Y, Aziz NA, et al. Discontinuation of penicillamine in the absence of alternative orphan medicines (trientine-zinc): a case of decompensated liver cirrhosis in Wilson\u2019s disease. J Clin Pharm Ther, 2007, 32(1):101\u2013107","journal-title":"J Clin Pharm Ther"},{"issue":"3","key":"1190_CR9","first-page":"149","volume":"18","author":"XP Wang","year":"2003","unstructured":"Wang XP, Yang RM, Ren MS, et al. Anticopper efficacy of captopril and sodium dimercaptosulphonate in patients with Wilson\u2019s disease. Funct Neurol, 2003,18(3):149\u2013153","journal-title":"Funct Neurol"}],"container-title":["Journal of Huazhong University of Science and Technology [Medical Sciences]"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-013-1190-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11596-013-1190-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-013-1190-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T17:11:01Z","timestamp":1559409061000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11596-013-1190-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["1190"],"URL":"https:\/\/doi.org\/10.1007\/s11596-013-1190-z","relation":{},"ISSN":["1672-0733","1993-1352"],"issn-type":[{"value":"1672-0733","type":"print"},{"value":"1993-1352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}