{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:31:35Z","timestamp":1769149895771,"version":"3.49.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CURR MED SCI"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s11596-022-2525-4","type":"journal-article","created":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T16:02:17Z","timestamp":1645977737000},"page":"483-490","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Extracts of Bauhinia Championii Alleviate Acute Neuronal Injury After Ischemic Reperfusion by Improving Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis"],"prefix":"10.1007","volume":"42","author":[{"given":"Mei","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-xi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,27]]},"reference":[{"key":"2525_CR1","doi-asserted-by":"publisher","first-page":"117200","DOI":"10.1016\/j.jns.2020.117200","volume":"419","author":"TH Fan","year":"2020","unstructured":"Fan TH, Khoury J, Cho S-M, et al. Cerebrovascular complications and vasculopathy in patients with herpes simplex virus central nervous system infection. J Neurol Sci, 2020,419:117200","journal-title":"J Neurol Sci"},{"issue":"5","key":"2525_CR2","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/S0361-9230(96)00294-8","volume":"42","author":"S Stolc","year":"1997","unstructured":"Stolc S, Vlkolinsk\u00fd R, Pavl\u00e1sek J. Neuroprotection by the pyridoindole stobadine: a minireview. Brain Res Bull, 1997,42(5):335\u2013340","journal-title":"Brain Res Bull"},{"key":"2525_CR3","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1007\/s00467-018-3984-5","volume":"34","author":"JL Martin","year":"2019","unstructured":"Martin JL, Gruszczyk AV, Beach TE, et al. Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Pediatr Nephrol, 2019,34:1167\u20131174","journal-title":"Pediatr Nephrol"},{"key":"2525_CR4","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.lfs.2017.05.014","volume":"180","author":"D Wu","year":"2017","unstructured":"Wu D, Wang J, Wang H, et al. Protective roles of bioactive peptides during ischemia-reperfusion injury: From bench to bedside. Life Sci, 2017,180:83\u201392","journal-title":"Life Sci"},{"key":"2525_CR5","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1146\/annurev-pathol-012513-104649","volume":"10","author":"SA Oakes","year":"2015","unstructured":"Oakes SA, Papa FR. The role of endoplasmic reticulum stress in human pathology. Annu Rev Pathol, 2015,10: 173\u2013194","journal-title":"Annu Rev Pathol"},{"issue":"3","key":"2525_CR6","doi-asserted-by":"publisher","first-page":"350","DOI":"10.3390\/nu10030350","volume":"10","author":"M Lepretti","year":"2018","unstructured":"Lepretti M, Martucciello S, Burgos Aceves MA, et al. Omega-3 Fatty Acids and Insulin Resistance: Focus on the Regulation of Mitochondria and Endoplasmic Reticulum Stress. Nutrients, 2018,10(3):350","journal-title":"Nutrients"},{"issue":"46","key":"2525_CR7","doi-asserted-by":"publisher","first-page":"11085","DOI":"10.1523\/JNEUROSCI.1294-17.2017","volume":"37","author":"BA Martinez","year":"2017","unstructured":"Martinez BA, Petersen DA, Gaeta AL, et al. Dysregulation of the mitochondrial unfolded protein response induces Non-Apoptotic dopaminergic neurodegeneration in C. elegans models of parkinson\u2019s disease. J Neurosci, 2017,37(46):11085\u201311100","journal-title":"J Neurosci"},{"key":"2525_CR8","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.jep.2016.03.035","volume":"185","author":"W Xu","year":"2016","unstructured":"Xu W, Huang M, Zhang Y, et al. Extracts of Bauhinia championii (Benth.) Benth. inhibit NF-<kappa>B-signaling in a rat model of collagen-induced arthritis and primary synovial cells. J Ethnopharmacol, 2016, 185:140\u2013146","journal-title":"J Ethnopharmacol"},{"key":"2525_CR9","doi-asserted-by":"publisher","first-page":"2577","DOI":"10.1080\/14786419.2018.1428594","volume":"32","author":"LP Hua","year":"2018","unstructured":"Hua LP, Zhang YQ, Ye M, et al. A new polyoxygenated abietane diterpenoid from the rattans of Bauhinia championii (Benth.) Benth. Nat Prod Res, 2018,32:2577\u20132582","journal-title":"Nat Prod Res"},{"key":"2525_CR10","doi-asserted-by":"crossref","first-page":"9806160","DOI":"10.1155\/2018\/9806160","volume":"2018","author":"Y Zhang","year":"2018","unstructured":"Zhang Y, Yan G, Sun C, et al. Apoptosis Effects of Dihydrokaempferol Isolated from Bauhinia championii on Synoviocytes. Evid Based Complement Alternat Med, 2018,2018:9806160","journal-title":"Evid Based Complement Alternat Med"},{"key":"2525_CR11","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1142\/S0192415X13500286","volume":"41","author":"W Xu","year":"2013","unstructured":"Xu W, Chu K, Li H, et al. Bauhinia championii Extraction Treatment of Collagen-Induced Arthritis via Downregulation of the Expression of TLR4, MyD88 and NF-\u03baB. Am J Chin Med, 2013,41:379\u2013390","journal-title":"Am J Chin Med"},{"key":"2525_CR12","first-page":"5933","volume":"9","author":"J Jian","year":"2015","unstructured":"Jian J, Xuan F, Qin F, et al. Bauhinia championii flavone inhibits apoptosis and autophagy via the PI3K\/Akt pathway in myocardial ischemia\/reperfusion injury in rats. Drug Des Devel Ther, 2015,9:5933\u20135945","journal-title":"Drug Des Devel Ther"},{"key":"2525_CR13","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.neuint.2004.06.006","volume":"46","author":"D Koubi","year":"2005","unstructured":"Koubi D, Jiang H, Zhang L, et al. Role of Bcl-2 family of proteins in mediating apoptotic death of PC12 cells exposed to oxygen and glucose deprivation. Neurochem Int, 2005,46:73\u201381","journal-title":"Neurochem Int"},{"key":"2525_CR14","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1016\/j.biopha.2018.09.167","volume":"108","author":"F Xu","year":"2018","unstructured":"Xu F, Ma R, Zhang G, et al. Estrogen and propofol combination therapy inhibits endoplasmic reticulum stress and remarkably attenuates cerebral ischemia-reperfusion injury and OGD injury in hippocampus. Biomed Pharmacother, 2018,108:1596\u20131606","journal-title":"Biomed Pharmacother"},{"key":"2525_CR15","doi-asserted-by":"publisher","first-page":"2925","DOI":"10.1177\/0300060518781382","volume":"46","author":"J Cheng","year":"2018","unstructured":"Cheng J, Zhu P, Qin H, et al. Dexmedetomidine attenuates cerebral ischemia\/reperfusion injury in neonatal rats by inhibiting TLR4 signaling. J Int Med Res, 2018,46:2925\u20132932","journal-title":"J Int Med Res"},{"issue":"10","key":"2525_CR16","doi-asserted-by":"publisher","first-page":"e3080","DOI":"10.1038\/cddis.2017.465","volume":"8","author":"L Gong","year":"2017","unstructured":"Gong L, Tang Y, An R, et al. RTN1-C mediates cerebral ischemia\/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways. Cell Death Dis, 2017,8(10):e3080","journal-title":"Cell Death Dis"},{"key":"2525_CR17","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1142\/S0192415X20500366","volume":"48","author":"YF Chen","year":"2020","unstructured":"Chen YF, Lee AS, Chen WY, et al. Partitioned Extracts of Bauhinia championii Induce G0\/G1 Phase Arrest and Apoptosis in Human Colon Cancer Cells. Am J Chin Med, 2020,48:719\u2013736","journal-title":"Am J Chin Med"},{"key":"2525_CR18","doi-asserted-by":"publisher","first-page":"14323","DOI":"10.3390\/molecules171214323","volume":"17","author":"W Xu","year":"2012","unstructured":"Xu W, Chu K, Li H, et al. Ionic liquid-based microwave-assisted extraction of flavonoids from Bauhinia championii (Benth.) Benth. Molecules, 2012,17:14323\u201314335","journal-title":"Molecules"},{"key":"2525_CR19","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.3892\/mmr.2013.1368","volume":"7","author":"L Cai","year":"2013","unstructured":"Cai L, Ye H, Yu F, et al. Effects of Bauhinia championii (Benth.) Benth. polysaccharides on the proliferation and cell cycle of chondrocytes. Mol Med Rep, 2013,7:1624\u20131630","journal-title":"Mol Med Rep"},{"key":"2525_CR20","first-page":"1","volume":"2019","author":"B Fu","year":"2019","unstructured":"Fu B, Zeng Q, Zhang Z, et al. Epicatechin Gallate Protects HBMVECs from Ischemia\/Reperfusion Injury through Ameliorating Apoptosis and Autophagy and Promoting Neovascularization. Oxid Med Cell Longev, 2019,2019:1\u201311","journal-title":"Oxid Med Cell Longev"},{"issue":"8","key":"2525_CR21","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.3390\/nu10081021","volume":"10","author":"C Kim","year":"2018","unstructured":"Kim C, Kim B. Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review. Nutrients, 2018,10(8):1021","journal-title":"Nutrients"},{"issue":"1","key":"2525_CR22","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1039\/C5FO00913H","volume":"7","author":"J Ma","year":"2016","unstructured":"Ma J, Luo R, Jiang H, et al. Quercitrin offers protection against brain injury in mice by inhibiting oxidative stress and inflammation. Food Funct, 2016,7(1):549\u2013556","journal-title":"Food Funct"},{"issue":"15","key":"2525_CR23","doi-asserted-by":"publisher","first-page":"3630","DOI":"10.3390\/ijms20153630","volume":"20","author":"M Pervin","year":"2019","unstructured":"Pervin M, Unno K, Takagaki A, et al. Function of green tea catechins in the brain: Epigallocatechin gallate and its metabolites. Int J Mol Sci, 2019,20(15):3630","journal-title":"Int J Mol Sci"},{"issue":"6","key":"2525_CR24","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.3390\/molecules23061297","volume":"23","author":"M Pervin","year":"2018","unstructured":"Pervin M, Unno K, Ohishi T, et al. Beneficial Effects of Green Tea Catechins on Neurodegenerative Diseases. Molecules, 2018,23(6):1297","journal-title":"Molecules"},{"issue":"3","key":"2525_CR25","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1124\/jpet.119.260117","volume":"371","author":"Y Qi","year":"2019","unstructured":"Qi Y, Yang C, Jiang Z, et al. Epicatechin-3-Gallate Signaling and Protection against Cardiac Ischemia\/Reperfusion Injury. J Pharmacol Exp Ther, 2019,371(3):663\u2013674","journal-title":"J Pharmacol Exp Ther"},{"issue":"1","key":"2525_CR26","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s12937-016-0179-4","volume":"15","author":"NA Singh","year":"2016","unstructured":"Singh NA, Mandal AK, Khan ZA. Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG). Nutr J, 2016,15(1):60","journal-title":"Nutr J"},{"key":"2525_CR27","first-page":"5105","volume":"127","author":"J Villanueva","year":"2014","unstructured":"Villanueva J, Viniegra S, Gimenez-Molina Y, et al. The position of mitochondria and ER in relation to that of the secretory sites in chromaffin cells. J Cell Sci, 2014,127:5105\u20135114","journal-title":"J Cell Sci"},{"key":"2525_CR28","first-page":"4163","volume":"18","author":"Z Wu","year":"2018","unstructured":"Wu Z, Wang H, Fang S, et al. Roles of endoplasmic reticulum stress and autophagy on H2O2induced oxidative stress injury in HepG2 cells. Mol Med Rep, 2018,18:4163\u20134174","journal-title":"Mol Med Rep"},{"key":"2525_CR29","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/s41419-017-0166-5","volume":"9","author":"K Huang","year":"2018","unstructured":"Huang K, Chen Y, Zhang R, et al. Honokiol induces apoptosis and autophagy via the ROS\/ERK1\/2 signaling pathway in human osteosarcoma cells in vitro and in vivo. Cell Death Dis, 2018,9:157","journal-title":"Cell Death Dis"},{"issue":"3","key":"2525_CR30","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.tibs.2015.01.002","volume":"40","author":"D Senft","year":"2015","unstructured":"Senft D, Ronai ZA. UPR, autophagy, and mitochondria crosstalk underlies the ER stress response. Trends Biochem Sci, 2015,40(3):141\u2013148","journal-title":"Trends Biochem Sci"},{"key":"2525_CR31","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1080\/15548627.2019.1606647","volume":"16","author":"H Yang","year":"2020","unstructured":"Yang H, Wen Y, Zhang M, et al. MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint. Autophagy, 2020,16:271\u2013288","journal-title":"Autophagy"},{"key":"2525_CR32","doi-asserted-by":"publisher","first-page":"190","DOI":"10.3389\/fncel.2019.00190","volume":"13","author":"S Yi","year":"2019","unstructured":"Yi S, Chen K, Zhang L, et al. Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways. Front Cell Neurosci, 2019,13:190","journal-title":"Front Cell Neurosci"},{"key":"2525_CR33","doi-asserted-by":"publisher","first-page":"6234","DOI":"10.1002\/cam4.1862","volume":"7","author":"M Zhang","year":"2018","unstructured":"Zhang M, Han N, Jiang Y, et al. EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK-eIF2alpha-GRP94 and IRE1alpha-XBP1-GRP78. Cancer Med, 2018,7:6234\u20136246","journal-title":"Cancer Med"},{"issue":"12","key":"2525_CR34","doi-asserted-by":"publisher","first-page":"3460","DOI":"10.1016\/j.bbamcr.2013.06.028","volume":"1833","author":"R Sano","year":"2013","unstructured":"Sano R, Reed JC. ER stress-induced cell death mechanisms. Biochim Biophys Acta, 2013,1833(12):3460\u20133470","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"2525_CR35","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1046\/j.1439-0264.2002.00398.x","volume":"31","author":"CS Van","year":"2002","unstructured":"Van CS, Van DBW. Morphological and biochemical aspects of apoptosis, oncosis and necrosis. Anat Histol Embryol, 2002,31(4):214\u2013223","journal-title":"Anat Histol Embryol"},{"issue":"4","key":"2525_CR36","doi-asserted-by":"publisher","first-page":"603","DOI":"10.18632\/aging.100934","volume":"8","author":"G Pistritto","year":"2016","unstructured":"Pistritto G, Trisciuoglio D, Ceci C, Garufi A, D\u2019Orazi G. Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies. Aging (Albany NY), 2016,8(4):603\u2013619","journal-title":"Aging (Albany NY)"},{"key":"2525_CR37","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/jpi.12264","volume":"59","author":"A Fernandez","year":"2015","unstructured":"Fernandez A, Ordonez R, Reiter RJ, et al. Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis. J Pineal Res, 2015,59:292\u2013307","journal-title":"J Pineal Res"},{"issue":"4","key":"2525_CR38","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1046\/j.1365-2591.2003.00657.x","volume":"36","author":"PG Satchell","year":"2003","unstructured":"Satchell PG, Gutmamn JL, Witherspoon DE. Apoptosis: an introduction for the endodontist. Int Endod J, 2003,36(4):237\u2013245","journal-title":"Int Endod J"},{"key":"2525_CR39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.drup.2009.02.002","volume":"12","author":"L Qiao","year":"2009","unstructured":"Qiao L, Wong BC. Targeting apoptosis as an approach for gastrointestinal cancer therapy. Drug Resist Updat, 2009,12:55\u201364","journal-title":"Drug Resist Updat"},{"key":"2525_CR40","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.blre.2017.08.004","volume":"32","author":"H Wu","year":"2018","unstructured":"Wu H, Medeiros LJ, Young KH. Apoptosis signaling and BCL-2 pathways provide opportunities for novel targeted therapeutic strategies in hematologic malignances. Blood Rev, 2018,32:8\u201328","journal-title":"Blood Rev"},{"key":"2525_CR41","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.3389\/fimmu.2018.02363","volume":"9","author":"MS Chimenti","year":"2018","unstructured":"Chimenti MS, Sunzini F, Fiorucci L, et al. Potential Role of Cytochrome c and Tryptase in Psoriasis and Psoriatic Arthritis Pathogenesis: Focus on Resistance to Apoptosis and Oxidative Stress. Front Immunol, 2018, 9:2363","journal-title":"Front Immunol"},{"key":"2525_CR42","doi-asserted-by":"publisher","first-page":"2108","DOI":"10.1016\/j.transproceed.2019.03.026","volume":"51","author":"Y Xiong","year":"2019","unstructured":"Xiong Y, Fan L, Tu Q, et al. Cytochrome b5 Interacts With Cytochrome C and Inhibits Hepatocyte Apoptosis in Brain-dead Rabbit Donors. Transplant Proc, 2019, 51:2108\u20132115","journal-title":"Transplant Proc"},{"key":"2525_CR43","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1021\/acschemneuro.8b00356","volume":"10","author":"J Liu","year":"2019","unstructured":"Liu J, Liu W, Yang H. Balancing Apoptosis and Autophagy for Parkinson\u2019s Disease Therapy: Targeting BCL-2. ACS Chem Neurosci, 2019,10:792\u2013802","journal-title":"ACS Chem Neurosci"},{"issue":"2","key":"2525_CR44","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.bbadis.2005.07.002","volume":"1762","author":"LM Dejean","year":"2006","unstructured":"Dejean LM, Martinez-Caballero S, Manon S, et al. Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins. Biochim Biophys Acta, 2006,1762(2):191\u2013201","journal-title":"Biochim Biophys Acta"},{"key":"2525_CR45","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1080\/21691401.2019.1580286","volume":"47","author":"M Hormozi","year":"2019","unstructured":"Hormozi M, Ghoreishi S, Baharvand P. Astaxanthin induces apoptosis and increases activity of antioxidant enzymes in LS-180 cells. Artif Cells Nanomed Biotechnol, 2019,47:891\u2013895","journal-title":"Artif Cells Nanomed Biotechnol"},{"key":"2525_CR46","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s11010-019-03642-4","volume":"463","author":"MDK Zahid","year":"2020","unstructured":"Zahid MDK, Rogowski M, Ponce C, et al. CCAAT\/enhancer-binding protein beta (C\/EBPbeta) knockdown reduces inflammation, ER stress, and apoptosis, and promotes autophagy in oxLDL-treated RAW264.7 macrophage cells. Mol Cell Biochem, 2020,463:211\u2013223","journal-title":"Mol Cell Biochem"},{"key":"2525_CR47","doi-asserted-by":"publisher","first-page":"7029","DOI":"10.1111\/jcmm.14600","volume":"23","author":"W Cao","year":"2019","unstructured":"Cao W, Zhang T, Feng R, et al. Hoxa5 alleviates obesity-induced chronic inflammation by reducing ER stress and promoting M2 macrophage polarization in mouse adipose tissue. J Cell Mol Med, 2019,23:7029\u20137042","journal-title":"J Cell Mol Med"}],"container-title":["Current Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-022-2525-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11596-022-2525-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-022-2525-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T11:04:14Z","timestamp":1726743854000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11596-022-2525-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,27]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["2525"],"URL":"https:\/\/doi.org\/10.1007\/s11596-022-2525-4","relation":{},"ISSN":["2096-5230","2523-899X"],"issn-type":[{"value":"2096-5230","type":"print"},{"value":"2523-899X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,27]]},"assertion":[{"value":"27 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}