{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:01:44Z","timestamp":1788184904701,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CURR MED SCI"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s11596-022-2662-9","type":"journal-article","created":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T12:02:37Z","timestamp":1677844957000},"page":"206-212","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aortic Dissection Research in China: Analysis of Studies Funded by the National Natural Science Foundation of China"],"prefix":"10.1007","volume":"43","author":[{"given":"Zhang","family":"Yue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-shuai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-hong","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-fan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,3]]},"reference":[{"key":"2662_CR1","unstructured":"Pape LA, Awais M, Woznicki EM, et al. Presentation, Diagnosis, and Outcomes of Acute Aortic Dissection: 17-Year Trends From the International Registry of Acute Aortic Dissection. J Am Coll Cardiol, 2015,66(4):350-358"},{"issue":"17","key":"2662_CR2","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1161\/CIRCULATIONAHA.117.031264","volume":"137","author":"A Evangelista","year":"2018","unstructured":"Evangelista A, Isselbacher EM, Bossone E, et al. Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research. Circulation, 2018,137(17):1846\u20131860","journal-title":"Circulation"},{"issue":"7","key":"2662_CR3","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1093\/ehjacc\/zuab031","volume":"10","author":"T Yamaguchi","year":"2021","unstructured":"Yamaguchi T, Nakai M, Yano T, et al. Populationbased incidence and outcomes of acute aortic dissection in Japan. Eur Heart J Acute Cardiovasc Care, 2021,10(7):701\u2013709","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"9","key":"2662_CR4","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1161\/CIRCULATIONAHA.110.015081","volume":"123","author":"L Sun","year":"2011","unstructured":"Sun L, Qi R, Zhu J, et al. Total arch replacement combined with stented elephant trunk implantation: a new \u201cstandard\u201d therapy for type a dissection involving repair of the aortic arch? Circulation, 2011,123(9):971-97","journal-title":"Circulation"},{"issue":"10","key":"2662_CR5","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.amjmed.2013.04.020","volume":"126","author":"E Bossone","year":"2013","unstructured":"Bossone E, Pyeritz RE, O\u2019Gara P, et al. Acute aortic dissection in blacks: insights from the International Registry of Acute Aortic Dissection. Am J Med, 2013,126(10):909\u2013915","journal-title":"Am J Med"},{"issue":"4","key":"2662_CR6","first-page":"241","volume":"55","author":"LZ Sun","year":"2017","unstructured":"Sun LZ, Li JR. Progress and challenge of Stanford type A aortic dissection in China. Zhonghua Wai Ke Za Zhi (Chinese), 2017,55(4):241\u2013244","journal-title":"Zhonghua Wai Ke Za Zhi (Chinese)"},{"issue":"12","key":"2662_CR7","doi-asserted-by":"publisher","first-page":"267","DOI":"10.21037\/atm.2019.05.63","volume":"7","author":"Y Liu","year":"2019","unstructured":"Liu Y, Gao Z, Wang H, et al. Analysis of projects funded by the National Natural Science Foundation of China during the years of 2014\u20132018. Ann Transl Med, 2019,7(12):267","journal-title":"Ann Transl Med"},{"issue":"24","key":"2662_CR8","doi-asserted-by":"publisher","first-page":"e16013","DOI":"10.1097\/MD.0000000000016013","volume":"98","author":"Y Su","year":"2019","unstructured":"Su Y, Li Q, Zheng Z, et al. Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in aortic dissection. Medicine (Baltimore), 2019,98(24):e16013","journal-title":"Medicine (Baltimore)"},{"issue":"3","key":"2662_CR9","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.21037\/jtd.2018.03.27","volume":"10","author":"E Sbarouni","year":"2018","unstructured":"Sbarouni E, Georgiadou P. MicroRNAs in acute aortic dissection. J Thorac Dis, 2018,10(3):1256\u20131257","journal-title":"J Thorac Dis"},{"issue":"6","key":"2662_CR10","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.1016\/j.jtcvs.2017.06.019","volume":"154","author":"Y Yu","year":"2017","unstructured":"Yu Y, Shi E, Gu T, et al. Overexpression of microRNA-30a contributes to the development of aortic dissection by targeting lysyl oxidase. J Thorac Cardiovasc Surg, 2017,154(6):1862\u20131869","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"10","key":"2662_CR11","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1161\/CIRCRESAHA.115.304361","volume":"115","author":"A Zampetaki","year":"2014","unstructured":"Zampetaki A, Attia R, Mayr U, et al. Role of miR-195 in aortic aneurysmal disease. Circ Res, 2014,115(10):857\u2013866","journal-title":"Circ Res"},{"issue":"122","key":"2662_CR12","doi-asserted-by":"publisher","first-page":"122r","DOI":"10.1126\/scitranslmed.3003441","volume":"4","author":"L Maegdefessel","year":"2012","unstructured":"Maegdefessel L, Azuma J, Toh R, et al. MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion. Sci Transl Med, 2012,4(122):122r","journal-title":"Sci Transl Med"},{"issue":"2","key":"2662_CR13","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1161\/CIRCRESAHA.111.253740","volume":"110","author":"DR Merk","year":"2012","unstructured":"Merk DR, Chin JT, Dake BA, et al. miR-29b participates in early aneurysm development in Marfan syndrome. Circ Res, 2012,110(2):312\u2013324","journal-title":"Circ Res"},{"issue":"2","key":"2662_CR14","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/ng.744","volume":"43","author":"IM van de Laar","year":"2011","unstructured":"van de Laar IM, Oldenburg RA, Pals G, et al. Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. Nat Genet, 2011,43(2):121\u2013126","journal-title":"Nat Genet"},{"issue":"3","key":"2662_CR15","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1038\/ng1511","volume":"37","author":"BL Loeys","year":"2005","unstructured":"Loeys BL, Chen J, Neptune ER, et al. A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat Genet, 2005,37(3):275\u2013281","journal-title":"Nat Genet"},{"issue":"5","key":"2662_CR16","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1172\/JCI67356","volume":"123","author":"P Ye","year":"2013","unstructured":"Ye P, Chen W, Wu J, et al. GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency. J Clin Invest, 2013,123(5):2317\u20132331","journal-title":"J Clin Invest"},{"issue":"5","key":"2662_CR17","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1161\/ATVBAHA.117.310694","volume":"38","author":"X Huang","year":"2018","unstructured":"Huang X, Yue Z, Wu J, et al. MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-beta-SMAD3 Signaling. Arterioscler Thromb Vasc Biol, 2018,38(5):1086\u20131101","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"22","key":"2662_CR18","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1056\/NEJMoa1404731","volume":"371","author":"RV Lacro","year":"2014","unstructured":"Lacro RV, Dietz HC, Sleeper LA, et al. Atenolol versus losartan in children and young adults with Marfan\u2019s syndrome. N Engl J Med, 2014,371(22):2061\u20132071","journal-title":"N Engl J Med"},{"key":"2662_CR19","first-page":"217190","volume-title":"Int J Cardiol","author":"L Gao","year":"2016","unstructured":"Gao L, Chen L, Fan L, et al. The effect of losartan on progressive aortic dilatation in patients with Marfan\u2019s syndrome: a meta-analysis of prospective randomized clinical trials. Int J Cardiol, 2016,217190\u2013194"}],"container-title":["Current Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-022-2662-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11596-022-2662-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-022-2662-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T12:18:38Z","timestamp":1677845918000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11596-022-2662-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["2662"],"URL":"https:\/\/doi.org\/10.1007\/s11596-022-2662-9","relation":{},"ISSN":["2096-5230","2523-899X"],"issn-type":[{"value":"2096-5230","type":"print"},{"value":"2523-899X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"28 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no conflicts of interest to declare.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest Statement"}}]}}