{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:57:45Z","timestamp":1792623465202,"version":"4.5.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T00:00:00Z","timestamp":1679097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T00:00:00Z","timestamp":1679097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["CURR MED SCI"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s11596-023-2707-8","type":"journal-article","created":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T03:02:46Z","timestamp":1679108566000},"page":"261-267","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Gene Repair of iPSC Line with GARS (G294R) Mutation of CMT2D Disease by CRISPR\/Cas9"],"prefix":"10.1007","volume":"43","author":[{"given":"Pei-jie","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-chun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-nan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-shuai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-lin","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-ming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,18]]},"reference":[{"issue":"10","key":"2707_CR1","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1038\/nrneurol.2013.179","volume":"9","author":"AM Rossor","year":"2013","unstructured":"Rossor AM, Polke JM, Houlden H, et al. Clinical implications of genetic advances in Charcot-Marie-Tooth disease. Nat Rev Neurol, 2013,9(10):562\u2013571","journal-title":"Nat Rev Neurol"},{"issue":"9","key":"2707_CR2","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.1038\/s41431-019-0403-8","volume":"27","author":"A Peretti","year":"2019","unstructured":"Peretti A, Perie M, Vincent D, et al. LRSAM1 variants and founder effect in French families with ataxic form of Charcot-Marie-Tooth type 2. Eur J Hum Genet, 2019,27(9):1406\u20131418","journal-title":"Eur J Hum Genet"},{"issue":"16","key":"2707_CR3","doi-asserted-by":"publisher","first-page":"E3324","DOI":"10.1073\/pnas.1614557114","volume":"114","author":"JN Sleigh","year":"2017","unstructured":"Sleigh JN, Dawes JM, West SJ, et al. Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proc Natl Acad Sci USA, 2017,114(16):E3324\u2013E3333","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"2707_CR4","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1038\/s41467-018-03461-z","volume":"9","author":"Z Mo","year":"2018","unstructured":"Mo Z, Zhao X, Liu H, et al. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. Nat Commun, 2018,9(1):1007","journal-title":"Nat Commun"},{"issue":"12","key":"2707_CR5","doi-asserted-by":"publisher","first-page":"1958","DOI":"10.1161\/CIRCRESAHA.117.311080","volume":"120","author":"Y Yoshida","year":"2017","unstructured":"Yoshida Y, Yamanaka S. Induced Pluripotent Stem Cells 10 Years Later: For Cardiac Applications. Circ Res, 2017,120(12):1958\u20131968","journal-title":"Circ Res"},{"issue":"9","key":"2707_CR6","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.celrep.2015.07.062","volume":"12","author":"AL Firth","year":"2015","unstructured":"Firth AL, Menon T, Parker GS, et al. Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs. Cell Rep, 2015,12(9):1385\u20131390","journal-title":"Cell Rep"},{"key":"2707_CR7","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3389\/fnmol.2018.00055","volume":"11","author":"SJ Grice","year":"2018","unstructured":"Grice SJ, Sleigh JN, Zameel Cader M. Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy. Front Mol Neurosci, 2018,11:55","journal-title":"Front Mol Neurosci"},{"issue":"7575","key":"2707_CR8","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1038\/nature15510","volume":"526","author":"W He","year":"2015","unstructured":"He W, Bai G, Zhou H, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature, 2015,526(7575):710\u2013714","journal-title":"Nature"},{"key":"2707_CR9","doi-asserted-by":"publisher","first-page":"7520","DOI":"10.1038\/ncomms8520","volume":"6","author":"S Niehues","year":"2015","unstructured":"Niehues S, Bussmann J, Steffes G, et al. Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat Commun, 2015,6:7520","journal-title":"Nat Commun"},{"issue":"R1","key":"2707_CR10","doi-asserted-by":"publisher","first-page":"R55","DOI":"10.1093\/hmg\/ddz131","volume":"28","author":"B Ravi","year":"2019","unstructured":"Ravi B, Antonellis A, Sumner CJ, et al. Genetic approaches to the treatment of inherited neuromuscular diseases. Hum Mol Genet, 2019,28(R1):R55\u2013R64","journal-title":"Hum Mol Genet"},{"issue":"1","key":"2707_CR11","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s40478-017-0475-z","volume":"5","author":"M Ortiz-Virumbrales","year":"2017","unstructured":"Ortiz-Virumbrales M, Moreno CL, Kruglikov I, et al. CRISPR\/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer\u2019s PSEN2 (N141I) neurons. Acta Neuropathol Commun, 2017,5(1):77\u201396","journal-title":"Acta Neuropathol Commun"},{"key":"2707_CR12","doi-asserted-by":"publisher","first-page":"32463","DOI":"10.1038\/srep32463","volume":"6","author":"Z Ou","year":"2016","unstructured":"Ou Z, Niu X, He W, et al. The Combination of CRISPR\/Cas9 and iPSC Technologies in the Gene Therapy of Human beta-thalassemia in Mice. Sci Rep, 2016,6:32463","journal-title":"Sci Rep"},{"issue":"2016","key":"2707_CR13","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.bcmd.2016.09.003","volume":"62","author":"X Hu","year":"2016","unstructured":"Hu X. CRISPR\/Cas9 system and its applications in human hematopoietic cells. Blood Cells Mol Dis, 2016,62(2016):6\u201312","journal-title":"Blood Cells Mol Dis"},{"key":"2707_CR14","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/978-1-4939-9424-3_36","volume":"1982","author":"CL Sweeney","year":"2019","unstructured":"Sweeney CL, Merling RK, De Ravin SS, et al. Gene Editing in Chronic Granulomatous Disease. Methods Mol Biol, 2019,1982:623\u2013665","journal-title":"Methods Mol Biol"},{"issue":"11","key":"2707_CR15","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.4155\/fmc-2018-0520","volume":"11","author":"JA Garcia-Leon","year":"2019","unstructured":"Garcia-Leon JA, Vitorica J, Gutierrez A. Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform. Future Med Chem, 2019,11(11):1305\u20131322","journal-title":"Future Med Chem"},{"issue":"2","key":"2707_CR16","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s10565-016-9370-9","volume":"33","author":"D Kumar","year":"2017","unstructured":"Kumar D, Anand T, Kues WA. Clinical potential of human-induced pluripotent stem cells: Perspectives of induced pluripotent stem cells. Cell Biol Toxicol, 2017,33(2):99\u2013112","journal-title":"Cell Biol Toxicol"},{"issue":"10","key":"2707_CR17","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1016\/j.celrep.2015.08.013","volume":"12","author":"CW Chang","year":"2015","unstructured":"Chang CW, Lai YS, Westin E, et al. Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR\/Cas9- Enhanced Gene Targeting. Cell Rep, 2015,12(10):1668\u20131677","journal-title":"Cell Rep"}],"container-title":["Current Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-023-2707-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11596-023-2707-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-023-2707-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T13:17:47Z","timestamp":1682515067000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11596-023-2707-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,18]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["2707"],"URL":"https:\/\/doi.org\/10.1007\/s11596-023-2707-8","relation":{},"ISSN":["2096-5230","2523-899X"],"issn-type":[{"value":"2096-5230","type":"print"},{"value":"2523-899X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,18]]},"assertion":[{"value":"4 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}