{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T06:55:00Z","timestamp":1763621700658,"version":"3.37.3"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T00:00:00Z","timestamp":1715385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T00:00:00Z","timestamp":1715385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004721","name":"The University of Tokyo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004721","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Jpn J Radiol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To compare computed tomography (CT) pulmonary angiography and unenhanced CT to determine the effect of rapid iodine contrast agent infusion on tracheal diameter and lung volume.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material and methods<\/jats:title>\n                <jats:p>This retrospective study included 101 patients who underwent CT pulmonary angiography and unenhanced CT, for which the time interval between them was within 365 days. CT pulmonary angiography was scanned 20 s after starting the contrast agent injection at the end-inspiratory level. Commercial software, which was developed based on deep learning technique, was used to segment the lung, and its volume was automatically evaluated. The tracheal diameter at the thoracic inlet level was also measured. Then, the ratios for the CT pulmonary angiography to unenhanced CT of the tracheal diameter (TD<jats:sub>PAU<\/jats:sub>) and both lung volumes (BLV<jats:sub>PAU<\/jats:sub>) were calculated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Tracheal diameter and both lung volumes were significantly smaller in CT pulmonary angiography (17.2\u2009\u00b1\u20092.6\u00a0mm and 3668\u2009\u00b1\u20091068\u00a0ml, respectively) than those in unenhanced CT (17.7\u2009\u00b1\u20092.5\u00a0mm and 3887\u2009\u00b1\u20091086\u00a0ml, respectively) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 for both). A statistically significant correlation was found between TD<jats:sub>PAU<\/jats:sub> and BLV<jats:sub>PAU<\/jats:sub> with a correlation coefficient of 0.451 (95% confidence interval, 0.280\u20130.594) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). No factor showed a significant association with TD<jats:sub>PAU<\/jats:sub>. The type of contrast agent had a significant association for BLV<jats:sub>PAU<\/jats:sub> (<jats:italic>p<\/jats:italic>\u2009=\u20090.042).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Rapid infusion of iodine contrast agent reduced the tracheal diameter and both lung volumes in CT pulmonary angiography, which was scanned at end-inspiratory level, compared with those in unenhanced CT.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s11604-024-01591-7","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T05:01:57Z","timestamp":1715403717000},"page":"1003-1011","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of rapid iodine contrast agent infusion on tracheal diameter and lung volume in CT pulmonary angiography measured with deep learning-based algorithm"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0324-6562","authenticated-orcid":false,"given":"Koichiro","family":"Yasaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,11]]},"reference":[{"issue":"2","key":"1591_CR1","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1148\/radiol.220370","volume":"305","author":"H Umakoshi","year":"2022","unstructured":"Umakoshi H, Nihashi T, Takada A, Hirasawa N, Ishihara S, Takehara Y, et al. Iodinated contrast media substitution to prevent recurrent hypersensitivity reactions: a systematic review and meta-analysis. Radiology. 2022;305(2):341\u20139.","journal-title":"Radiology"},{"issue":"1","key":"1591_CR2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1148\/radiol.12121460","volume":"267","author":"JS McDonald","year":"2013","unstructured":"McDonald JS, McDonald RJ, Comin J, Williamson EE, Katzberg RW, Murad MH, et al. Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology. 2013;267(1):119\u201328.","journal-title":"Radiology"},{"issue":"7","key":"1591_CR3","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1007\/s003300000729","volume":"11","author":"SK Morcos","year":"2001","unstructured":"Morcos SK, Thomsen HS. Adverse reactions to iodinated contrast media. 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Approval was granted by the Ethics Committee of Graduate School of Medicine, The University of Tokyo. (Date May 2009\/No 2561-(25)).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Requirement for obtaining written informed consent was waived by the Ethics Committee due to the retrospective nature of this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}