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For 15 patients with non-metastatic PCa, two different plans (BROAD-RT and co-VMAT) were created, and these plans and dosimetric indices were compared. The prescribed dose was 35\u00a0Gy in 5 fractions to the whole prostate gland, and that to the intra-prostatic dominant lesions (IPDLs) was increased up to 50\u00a0Gy. Quality assurance (QA) was performed for BROAD-RT and co-VMAT plans from the 15 patients, and the calculated and measured dose distributions were evaluated according to global gamma analysis using ArcCHECK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The dose coverage of the target volumes and the high-dose exposure to organs at risk (rectum, bladder, and urethra) were not significantly different between BROAD-RT and co-VMAT plans. The normal tissue dose outside of the planning target volume (PTV) (maximum dose 2\u00a0cm away from PTV [D2 cm], and 30%, 50%, or 70% isodose volume divided by the volume of PTV [R30, R50, and R70]) were significantly lower in the BROAD-RT plan (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, respectively). In QA, average (\u00b1\u2009standard deviation) passing rates were 98.2\u2009\u00b1\u20090.7% for BROAD-RT and 99.0\u2009\u00b1\u20091.0% for co-VMAT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Non-coplanar VMAT via BROAD-RT improved the dose distribution, mainly outside of the PTV and for some of the organs at risks, in prostate SBRT with focal boost compared with coplanar VMAT. Therefore, as BROAD-RT enables practical implementation of non-coplanar VMAT, it is considered a promising radiotherapy method of SBRT with focal boost for non-metastatic PCa.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11604-026-01974-y","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:09:32Z","timestamp":1777525772000},"page":"1290-1298","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dosimetric advantages of non-coplanar volumetric modulated arc therapy (VMAT) using biaxially rotational dynamic radiation therapy compared with coplanar VMAT in prostate stereotactic body radiation therapy with focal boost"],"prefix":"10.1007","volume":"44","author":[{"given":"Rihito","family":"Aizawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Hirashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ogata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Hiraoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8135-8746","authenticated-orcid":false,"given":"Takashi","family":"Mizowaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"1974_CR1","doi-asserted-by":"crossref","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I et al. 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