{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:55:37Z","timestamp":1790654137681,"version":"4.1.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K14856"],"award-info":[{"award-number":["23K14856"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Jpn J Radiol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Preoperative breast magnetic resonance imaging (MRI) is the most sensitive modality for assessing disease extent in newly diagnosed breast cancer, detecting additional ipsilateral disease in approximately 20% of patients. While its impact on patients\u2019 prognosis is debated, MRI may refine surgical management when it is appropriately evaluated. This review provides a practical framework for optimizing MRI interpretation for individualized surgical planning, incorporating the updated American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) v2025 recommendations. Key updates in BI-RADS v2025 include the introduction of \u201cAdditional Close Findings\u201d to streamline the management of suspicious lesions within 2.0\u00a0cm of the index cancer. For oncoplastic procedures, MRI provides critical metrics: a tumor-nipple distance of &gt;\u20091.0\u00a0cm has been reported as a significant threshold under specific study conditions for predicting nipple involvement in nipple-sparing mastectomy, while an MRI-to-skin distance of 5\u00a0mm is a suggested threshold for predicting margin positivity in skin-sparing mastectomy. This review also addresses the assessment of pectoralis muscle involvement and the new BI-RADS section dedicated to lymph node evaluation. Furthermore, MRI is highlighted as an essential tool for identifying eligible candidates for radiofrequency ablation by precisely excluding multifocality and extensive intraductal components to satisfy strict clinical criteria. The integration of these standardized, surgically-relevant metrics allows radiologists to provide a detailed anatomical roadmap, which is essential to maximize cosmetic outcomes through conservative mastectomy techniques without compromising oncological safety.<\/jats:p>","DOI":"10.1007\/s11604-026-02033-2","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T07:30:21Z","timestamp":1781508621000},"page":"1745-1757","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["MRI-based assessment for optimal breast cancer local therapy in the era of BI-RADS v2025"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5337-3455","authenticated-orcid":false,"given":"Maya","family":"Honda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6212-3351","authenticated-orcid":false,"given":"Masako","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1991-2494","authenticated-orcid":false,"given":"Mami","family":"Iima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azusa","family":"Nishimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5783-8048","authenticated-orcid":false,"given":"Yuji","family":"Nakamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"2033_CR1","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s00330-011-2238-8","volume":"22","author":"MN Plana","year":"2012","unstructured":"Plana MN, Carreira C, Muriel A, Chiva M, Abraira V, Emparanza JI, et al. Magnetic resonance imaging in the preoperative assessment of patients with primary breast cancer: systematic review of diagnostic accuracy and meta-analysis. Eur Radiol. 2012;22:26\u201338. https:\/\/doi.org\/10.1007\/s00330-011-2238-8.","journal-title":"Eur Radiol"},{"key":"2033_CR2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.29741","author":"BN Dontchos","year":"2025","unstructured":"Dontchos BN, Phelps MD, Rahbar H, Lam DL. Pre-treatment breast MRI: clinical indications, outcomes, and future directions. J Magn Reson Imaging. 2025. https:\/\/doi.org\/10.1002\/jmri.29741.","journal-title":"J Magn Reson Imaging"},{"key":"2033_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta14010","volume":"14","author":"LW Turnbull","year":"2010","unstructured":"Turnbull LW, Brown SR, Olivier C, Harvey I, Brown J, Drew P, et al. Multicentre randomised controlled trial examining the cost-effectiveness of contrast-enhanced high field magnetic resonance imaging in women with primary breast cancer scheduled for wide local excision (COMICE). Health Technol Assess. 2010;14:1\u2013182. https:\/\/doi.org\/10.3310\/hta14010.","journal-title":"Health Technol Assess"},{"key":"2033_CR4","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/j.ejca.2010.11.035","volume":"47","author":"NHGM Peters","year":"2011","unstructured":"Peters NHGM, van Esser S, van den Bosch MAAJ, Storm RK, Plaisier PW, van Dalen T, et al. Preoperative MRI and surgical management in patients with nonpalpable breast cancer: the MONET\u2014randomised controlled trial. Eur J Cancer. 2011;47:879\u201386. https:\/\/doi.org\/10.1016\/j.ejca.2010.11.035.","journal-title":"Eur J Cancer"},{"key":"2033_CR5","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1200\/JCO.18.00595","volume":"37","author":"C Balleyguier","year":"2019","unstructured":"Balleyguier C, Dunant A, Ceugnart L, Kandel M, Chauvet M-P, Ch\u00e9rel P, et al. Preoperative breast magnetic resonance imaging in women with local ductal carcinoma in situ to optimize surgical outcomes: results from the randomized phase III trial IRCIS. J Clin Oncol. 2019;37:885\u201392. https:\/\/doi.org\/10.1200\/JCO.18.00595.","journal-title":"J Clin Oncol"},{"key":"2033_CR6","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1007\/s00268-014-2605-0","volume":"38","author":"V Gonzalez","year":"2014","unstructured":"Gonzalez V, Sandelin K, Karlsson A, \u00c5berg W, L\u00f6fgren L, Iliescu G, et al. Preoperative MRI of the breast (POMB) influences primary treatment in breast cancer: a prospective, randomized, multicenter study. World J Surg. 2014;38:1685\u201393. https:\/\/doi.org\/10.1007\/s00268-014-2605-0.","journal-title":"World J Surg"},{"key":"2033_CR7","doi-asserted-by":"publisher","first-page":"zrab088","DOI":"10.1093\/bjsopen\/zrab088","volume":"5","author":"V Gonzalez","year":"2021","unstructured":"Gonzalez V, Arver B, L\u00f6fgren L, Bergkvist L, Sandelin K, Eriksson S. Impact of preoperative breast MRI on 10-year survival of patients included in the Swedish randomized multicentre POMB trial. BJS Open. 2021;5:zrab088. https:\/\/doi.org\/10.1093\/bjsopen\/zrab088.","journal-title":"BJS Open"},{"key":"2033_CR8","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1007\/s00330-021-08240-x","volume":"32","author":"F Sardanelli","year":"2022","unstructured":"Sardanelli F, Trimboli RM, Houssami N, Gilbert FJ, Helbich TH, \u00c1lvarez Benito M, et al. Magnetic resonance imaging before breast cancer surgery: results of an observational multicenter international prospective analysis (MIPA). Eur Radiol. 2022;32:1611\u201323. https:\/\/doi.org\/10.1007\/s00330-021-08240-x.","journal-title":"Eur Radiol"},{"key":"2033_CR9","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1148\/radiol.2017161449","volume":"284","author":"CK Kuhl","year":"2017","unstructured":"Kuhl CK, Strobel K, Bieling H, Wardelmann E, Kuhn W, Maass N, et al. Impact of preoperative breast MR imaging and MR-guided surgery on diagnosis and surgical outcome of women with invasive breast cancer with and without DCIS component. Radiology. 2017;284:645\u201355. https:\/\/doi.org\/10.1148\/radiol.2017161449.","journal-title":"Radiology"},{"key":"2033_CR10","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1148\/radiol.2018171472","volume":"287","author":"SM Ha","year":"2018","unstructured":"Ha SM, Chae EY, Cha JH, Kim HH, Shin HJ, Choi WJ. Breast MR imaging before surgery: outcomes in patients with invasive lobular carcinoma by using propensity score matching. Radiology. 2018;287:771\u20137. https:\/\/doi.org\/10.1148\/radiol.2018171472.","journal-title":"Radiology"},{"key":"2033_CR11","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-024-11338-7","author":"A Di Cozzi","year":"2025","unstructured":"Cozzi A, Di Leo G, Houssami N, Gilbert FJ, Helbich TH, \u00c1lvarez Benito M, et al Preoperative breast MRI reduces reoperations for unilateral invasive lobular carcinoma: a patient-matched analysis from the MIPA study. Eur Radiol. 2025. . https:\/\/doi.org\/10.1007\/s00330-024-11338-7.","journal-title":"Eur Radiol"},{"key":"2033_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-023-10409-5","author":"A Cozzi","year":"2023","unstructured":"Cozzi A, Di Leo G, Houssami N, Gilbert FJ, Helbich TH, \u00c1lvarez Benito M, et al. Preoperative breast MRI positively impacts surgical outcomes of needle biopsy-diagnosed pure DCIS: a patient-matched analysis from the MIPA study. Eur Radiol. 2023. https:\/\/doi.org\/10.1007\/s00330-023-10409-5.","journal-title":"Eur Radiol"},{"key":"2033_CR13","unstructured":"Gradishar WJ, Chew H, Rugo HS, Dang C, Santa-Maria CA, Moran MS et al. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae), Breast Cancer Version 2.2026. National comprehensive cancer network; 2026. Available from: https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/breast.pdf [Accessed April 11, 2026]."},{"key":"2033_CR14","unstructured":"American Society of Breast Surgeons. Diagnostic and screening magnetic resonance imaging of the breast [Internet]. American Society of Breast Surgeons. 2018. Available from: https:\/\/www.breastsurgeons.org\/docs\/statements\/Consensus-Guideline-on-Diagnostic-and-Screening-Magnetic-Resonance-Imaging-of-the-Breast.pdf"},{"key":"2033_CR15","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1007\/s00330-008-0863-7","volume":"18","author":"RM Mann","year":"2008","unstructured":"Mann RM, Kuhl CK, Kinkel K, Boetes C, Breast MRI. Guidelines from the European society of breast imaging. Eur Radiol. 2008;18:1307\u201318. https:\/\/doi.org\/10.1007\/s00330-008-0863-7.","journal-title":"Eur Radiol"},{"key":"2033_CR16","volume-title":"Magnetic resonance imaging. ACR BI-RADS v2025 manual","author":"WB DeMartini","year":"2025","unstructured":"DeMartini WB, Strigel RM, Pinker K, Rahbar H, Wang LC. Magnetic resonance imaging. ACR BI-RADS v2025 manual. Reston, VA: American College of Radiology; 2025."},{"key":"2033_CR17","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1148\/radiol.2019182947","volume":"292","author":"RM Mann","year":"2019","unstructured":"Mann RM, Cho N, Moy L, Breast MRI. State of the art. Radiology. 2019;292:520\u201336. https:\/\/doi.org\/10.1148\/radiol.2019182947.","journal-title":"Radiology"},{"key":"2033_CR18","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s12282-023-01521-x","volume":"31","author":"K Kubota","year":"2024","unstructured":"Kubota K, Nakashima K, Nakashima K, Kataoka M, Inoue K, Goto M, et al. The Japanese breast cancer society clinical practice guidelines for breast cancer screening and diagnosis, 2022 edition. Breast Cancer. 2024;31:157\u201364. https:\/\/doi.org\/10.1007\/s12282-023-01521-x.","journal-title":"Breast Cancer"},{"key":"2033_CR19","doi-asserted-by":"publisher","first-page":"3380","DOI":"10.3390\/cancers17203380","volume":"17","author":"M-O Poenaru","year":"2025","unstructured":"Poenaru M-O, Amza M, Toma C-V, Augustin F-E, Pacu I, Zampieri G, et al. Multicentric and multifocal breast tumors-narrative literature review. Cancers (Basel). 2025;17:3380. https:\/\/doi.org\/10.3390\/cancers17203380.","journal-title":"Cancers (Basel)"},{"key":"2033_CR20","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1245\/s10434-023-14451-x","volume":"31","author":"AK Schulze","year":"2024","unstructured":"Schulze AK, Hoskin TL, Moldoveanu D, Sturz JL, Boughey JC. Tumor characteristics of bilateral breast cancer compared with unilateral breast cancer. Ann Surg Oncol. 2024;31:947\u201356. https:\/\/doi.org\/10.1245\/s10434-023-14451-x.","journal-title":"Ann Surg Oncol"},{"key":"2033_CR21","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021204136","author":"SJ Bae","year":"2021","unstructured":"Bae SJ, Cha YJ, Eun NL, Ji JH, Kim D, Lee J, et al Diagnostic accuracy of nonmass enhancement at breast MRI in predicting tumor involvement of the nipple: a prospective study in a single institution. Radiology. 2021. https:\/\/doi.org\/10.1148\/radiol.2021204136.","journal-title":"Radiology"},{"key":"2033_CR22","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.crad.2018.03.008","volume":"73","author":"G Mariscotti","year":"2018","unstructured":"Mariscotti G, Durando M, Houssami N, Berzovini CM, Esposito F, Fasciano M, et al. Preoperative MRI evaluation of lesion-nipple distance in breast cancer patients: thresholds for predicting occult nipple-areola complex involvement. Clin Radiol. 2018;73:735\u201343. https:\/\/doi.org\/10.1016\/j.crad.2018.03.008.","journal-title":"Clin Radiol"},{"key":"2033_CR23","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1148\/rg.210136","volume":"42","author":"SC Lee","year":"2022","unstructured":"Lee SC, Mendez-Broomberg K, Eacobacci K, Vincoff NS, Gupta E, McElligott SE. Nipple-sparing mastectomy: What the radiologist should know. Radiographics. 2022;42:321\u201339. https:\/\/doi.org\/10.1148\/rg.210136.","journal-title":"Radiographics"},{"key":"2033_CR24","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1148\/rg.2019180039","volume":"39","author":"Y Gao","year":"2019","unstructured":"Gao Y, Brachtel EF, Hernandez O, Heller SL. An analysis of nipple enhancement at breast MRI with radiologic-pathologic correlation. Radiographics. 2019;39:10\u201327. https:\/\/doi.org\/10.1148\/rg.2019180039.","journal-title":"Radiographics"},{"key":"2033_CR25","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1097\/00006534-199509001-00012","volume":"96","author":"H Nakajima","year":"1995","unstructured":"Nakajima H, Imanishi N, Aiso S. Arterial anatomy of the nipple-areola complex. Plast Reconstr Surg. 1995;96:843\u20135. https:\/\/doi.org\/10.1097\/00006534-199509001-00012.","journal-title":"Plast Reconstr Surg"},{"key":"2033_CR26","doi-asserted-by":"publisher","first-page":"6532","DOI":"10.1245\/s10434-023-13832-6","volume":"30","author":"A Ogiya","year":"2023","unstructured":"Ogiya A, Nagura N, Shimo A, Nogi H, Narui K, Seki H, et al. Long-term outcomes of breast cancer patients with local recurrence after mastectomy undergoing immediate breast reconstruction: A retrospective multi-institutional study of 4153 cases. Ann Surg Oncol. 2023;30:6532\u201340. https:\/\/doi.org\/10.1245\/s10434-023-13832-6.","journal-title":"Ann Surg Oncol"},{"key":"2033_CR27","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/tbj.13194","volume":"25","author":"A Kataoka","year":"2019","unstructured":"Kataoka A, Sawaki M, Okumura S, Onishi S, Iwase M, Sugino K, et al. Prediction of pathological margin status using preoperative contrast-enhanced MRI in patients with early breast cancer who underwent skin-sparing mastectomy. Breast J. 2019;25:202\u20136. https:\/\/doi.org\/10.1111\/tbj.13194.","journal-title":"Breast J"},{"key":"2033_CR28","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1007\/s12282-014-0572-9","volume":"22","author":"T Uematsu","year":"2015","unstructured":"Uematsu T. Focal breast edema associated with malignancy on T2-weighted images of breast MRI: peritumoral edema, prepectoral edema, and subcutaneous edema. Breast Cancer. 2015;22:66\u201370. https:\/\/doi.org\/10.1007\/s12282-014-0572-9.","journal-title":"Breast Cancer"},{"key":"2033_CR29","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1148\/radiology.214.1.r00ja1667","volume":"214","author":"EA Morris","year":"2000","unstructured":"Morris EA, Schwartz LH, Drotman MB, Kim SJ, Tan LK, Liberman L, et al. Evaluation of pectoralis major muscle in patients with posterior breast tumors on breast MR images: early experience. Radiology. 2000;214:67\u201372. https:\/\/doi.org\/10.1148\/radiology.214.1.r00ja1667.","journal-title":"Radiology"},{"key":"2033_CR30","doi-asserted-by":"publisher","first-page":"20201202","DOI":"10.1259\/bjr.20201202","volume":"94","author":"KS Myers","year":"2021","unstructured":"Myers KS, Stern E, Ambinder EB, Oluyemi ET. Breast cancer abutting the pectoralis major muscle on breast MRI: what are the clinical implications? Br J Radiol. 2021;94:20201202. https:\/\/doi.org\/10.1259\/bjr.20201202.","journal-title":"Br J Radiol"},{"key":"2033_CR31","doi-asserted-by":"publisher","first-page":"205846012513390","DOI":"10.1177\/20584601251339017","volume":"14","author":"TL Harada","year":"2025","unstructured":"Harada TL, Uematsu T, Nakashima K, Sugino T, Nishimura S, Hayashi T, et al. A preliminary study on diffusion-weighted imaging with background suppression and maximum intensity projection for screening internal mammary lymph node metastasis of breast cancer. Acta Radiol Open. 2025;14:20584601251339017. https:\/\/doi.org\/10.1177\/20584601251339017.","journal-title":"Acta Radiol Open"},{"key":"2033_CR32","doi-asserted-by":"publisher","first-page":"e114","DOI":"10.1016\/S1470-2045(23)00615-0","volume":"25","author":"M Toi","year":"2024","unstructured":"Toi M, Kinoshita T, Benson JR, Jatoi I, Kataoka M, Han W, et al. Non-surgical ablation for breast cancer: an emerging therapeutic option. Lancet Oncol. 2024;25:e114\u201325. https:\/\/doi.org\/10.1016\/S1470-2045(23)00615-0.","journal-title":"Lancet Oncol"},{"key":"2033_CR33","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-026-01951-5","author":"S Takayama","year":"2026","unstructured":"Takayama S, Murata T, Watase C, Maeda H, Nakashoji A, Ogawa A, et al Emerging advances in non-surgical ablation for early-stage breast cancer. Jpn J Radiol. 2026. . https:\/\/doi.org\/10.1007\/s11604-026-01951-5.","journal-title":"Jpn J Radiol"},{"key":"2033_CR34","unstructured":"Ministry of Health, Labour and Welfare. [Partial revision of the points to note in implementation accompanying the partial revision of the calculation method of medical fees]. 2023. Available from: https:\/\/www.mhlw.go.jp\/content\/12404000\/001173326.pdf (in Japanese). Accessed 11 April\u00a0 2026."},{"key":"2033_CR35","unstructured":"The Japan Breast Cancer Society. [Guidelines for the proper use of radiofrequency ablation (RFA) for breast cancer]. 2023. Available from: https:\/\/www.jbcs.gr.jp\/uploads\/files\/shikaku%20elearning\/RFA\/rfa.20231117.pdf (in Japanese) . Accessed\u00a0 11 April\u00a0 2026."},{"key":"2033_CR36","doi-asserted-by":"publisher","first-page":"e495","DOI":"10.1016\/j.clbc.2017.09.007","volume":"18","author":"T Ito","year":"2018","unstructured":"Ito T, Oura S, Nagamine S, Takahashi M, Yamamoto N, Yamamichi N, et al. Radiofrequency ablation of breast cancer: a retrospective study. Clin Breast Cancer. 2018;18:e495\u2013500. https:\/\/doi.org\/10.1016\/j.clbc.2017.09.007.","journal-title":"Clin Breast Cancer"},{"key":"2033_CR37","doi-asserted-by":"publisher","first-page":"e715","DOI":"10.1016\/j.clbc.2021.03.004","volume":"21","author":"EMF van de Voort","year":"2021","unstructured":"van de Voort EMF, Struik GM, Birnie E, Moelker A, Verhoef C, Klem TMAL. Thermal ablation as an alternative for surgical resection of small (\u2264\u20092 cm) breast cancers: a meta-analysis. Clin Breast Cancer. 2021;21:e715\u201330. https:\/\/doi.org\/10.1016\/j.clbc.2021.03.004.","journal-title":"Clin Breast Cancer"},{"key":"2033_CR38","doi-asserted-by":"publisher","first-page":"651646","DOI":"10.3389\/fonc.2021.651646","volume":"11","author":"L-Y Xia","year":"2021","unstructured":"Xia L-Y, Hu Q-L, Xu W-Y. Efficacy and safety of radiofrequency ablation for breast cancer smaller than 2 cm: a systematic review and meta-analysis. Front Oncol. 2021;11:651646. https:\/\/doi.org\/10.3389\/fonc.2021.651646.","journal-title":"Front Oncol"},{"key":"2033_CR39","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-026-19220-0","author":"T Kinoshita","year":"2026","unstructured":"Kinoshita T, Takayama S, Fujisawa T, Watanabe K, Yamamoto N, Shien T, et al. Radiofrequency ablation for early stage breast cancer as a potential alternative to partial mastectomy: 5-year results from the multiple-center, single-arm, phase 3 RAFAELO study (NCCH1409). Ann Surg Oncol. 2026. https:\/\/doi.org\/10.1245\/s10434-026-19220-0.","journal-title":"Ann Surg Oncol"}],"container-title":["Japanese Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11604-026-02033-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11604-026-02033-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11604-026-02033-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:09:15Z","timestamp":1790651355000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11604-026-02033-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,15]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["2033"],"URL":"https:\/\/doi.org\/10.1007\/s11604-026-02033-2","relation":{},"ISSN":["1867-1071","1867-108X"],"issn-type":[{"value":"1867-1071","type":"print"},{"value":"1867-108X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,15]]},"assertion":[{"value":"18 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Maya Honda and Masako Kataoka have received grants from Midtown Clinic Medical Corporation. Mami Iima is affiliated with the Department of Fundamental Development for Advanced Low Invasive Diagnostic Imaging, Nagoya University Graduate School of Medicine, which is financially supported by Hi-Medic, Inc. The remaining authors of this manuscript declare no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This is a review article and does not involve new primary research involving human subjects. However, the clinical images presented in this article were obtained from a retrospective study approved by the Institutional Review Board of Kyoto University Hospital (R0610). The requirement for informed consent for the use of clinical images was waived by the Institutional Review Board due to the retrospective nature of the study. An opt-out method was applied, providing patients the opportunity to decline participation.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}]}}