{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:31:12Z","timestamp":1793399472769,"version":"4.5.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Oita University","id":[{"id":"https:\/\/ror.org\/01nyv7k26","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Jpn J Radiol"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To characterize the computed tomography (CT) features of severe fever with thrombocytopenia syndrome (SFTS) and to identify imaging features predictive of an adverse prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Thirty-one patients diagnosed with SFTS between July 2017 and August 2025 and who underwent whole-body CT (17 men, 14 women; mean age, 75.3\u00a0years; 24 survivors, 7 non-survivors) were retrospectively reviewed. CT findings of the chest, abdominal organs, and regional lymph nodes were assessed. Initial CT scans (n\u2009=\u200931) were obtained a mean of 3.8\u00a0days (range, 0\u20137) after symptom onset, and follow-up CT scans (n\u2009=\u200920) were performed in 17 patients a mean of 6.0\u00a0days (range 1\u201318) after the initial scan, giving a total of 51 examinations. Additionally, for three cases in which autopsy was performed, correlation analysis was performed between the CT findings and pathological findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>On initial CT, the most frequent finding was regional lymphadenopathy (n\u2009=\u200930, 96.8%), most commonly involving inguinal (n\u2009=\u200917, 54.8%) and axillary nodes (n\u2009=\u200911, 35.5%). Perinodal fat stranding was observed in 29 patients (93.5%). The most common thoracic finding was ground-glass opacity (GGO) (n\u2009=\u200917, 54.8%), followed by bronchial wall thickening (n\u2009=\u200916, 51.6%) and interlobular septal thickening (n\u2009=\u200915, 48.4%). Among abdominal organs, splenomegaly was the most frequent finding (n\u2009=\u200925, 80.6%), followed by renal enlargement (n\u2009=\u200915, 48.4%). On follow-up CT, the most frequently observed changes compared with the initial CT were increased renal volume (n\u2009=\u200917, 85%) and increased hepatic volume (n\u2009=\u200914, 70%). GGO was significantly more frequent in non-survivors than in survivors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Characteristic CT findings of SFTS include regional lymphadenopathy with perinodal fat stranding, followed by splenomegaly and GGO. GGO may be an imaging finding predictive of an adverse prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11604-026-02044-z","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:09:39Z","timestamp":1782893379000},"page":"1958-1969","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Whole-body CT characteristics of patients with severe fever with thrombocytopenia syndrome"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8206-6582","authenticated-orcid":false,"given":"Haruka","family":"Sato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumito","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuichi","family":"Takenaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuzo","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruto","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Asayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"2044_CR1","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1056\/NEJMoa1010095","volume":"364","author":"X Yu","year":"2011","unstructured":"Yu X, Liang MF, Zhang SY, Liu Y, Li JD, Sun YL, et al. 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