{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T01:55:24Z","timestamp":1789178124136,"version":"build-2803163510"},"reference-count":41,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jgisurgery.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Gastrointestinal Surgery"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1007\/s11605-008-0796-0","type":"journal-article","created":{"date-parts":[[2009,1,30]],"date-time":"2009-01-30T15:06:45Z","timestamp":1233328005000},"page":"587-594","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Hemorrhage-Induced Hepatic Injury and Hypoperfusion can be Prevented by Direct Peritoneal Resuscitation"],"prefix":"10.1016","volume":"13","author":[{"given":"Ryan T.","family":"Hurt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El Rasheid","family":"Zakaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Matheson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahoney E.","family":"Cobb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Parker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Neal","family":"Garrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1007\/s11605-008-0796-0_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00024382-200115010-00001","article-title":"Post-injury multiple organ failure: the role of the gut","volume":"15","author":"Hassoun","year":"2001","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0015","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/00024382-199812000-00007","article-title":"Selective microvascular endothelial cell dysfunction in the small intestine following resuscitated hemorrhagic shock","volume":"10","author":"Fruchterman","year":"1998","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0020","first-page":"307","article-title":"Hemorrhage produces depression in microvascular blood flow which persists despite fluid resuscitation","volume":"32","author":"Wang","year":"1990","journal-title":"Circ Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0025","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/00024382-200212000-00014","article-title":"Resuscitation regimens for hemorrhagic shock must contain blood","volume":"18","author":"Zakaria","year":"2002","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0030","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00024382-199402000-00010","article-title":"Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock","volume":"1","author":"Deitch","year":"1994","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0035","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0022-4804(90)90014-S","article-title":"Hepatocellular dysfunction occurs early after hemorrhage and persists despite fluid resuscitation","volume":"48","author":"Wang","year":"1990","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0040","first-page":"H973","article-title":"Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation","volume":"265","author":"Wang","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1007\/s11605-008-0796-0_bb0045","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00024382-200402000-00014","article-title":"Impairment of endothelium-dependent dilation response after resuscitation from hemorrhagic shock involved postreceptor mechanisms","volume":"21","author":"Zakaria","year":"2004","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0050","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00000542-197408000-00006","article-title":"Mechanisms of blood flow and fluid exchange in microvessels: hemorrhagic hypotension model","volume":"41","author":"Zweifach","year":"1974","journal-title":"Anesthesiology"},{"key":"10.1007\/s11605-008-0796-0_bb0055","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1097\/01.SLA.0000064660.10461.9D","article-title":"Intraperitoneal resuscitation improves intestinal blood flow following hemorrhagic shock","volume":"237","author":"Zakaria","year":"2003","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-008-0796-0_bb0060","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/01.TA.0000152892.24841.54","article-title":"Direct peritoneal resuscitation from hemorrhagic shock: effect of time delay in therapy initiation","volume":"58","author":"Zakaria","year":"2005","journal-title":"J Trauma"},{"key":"10.1007\/s11605-008-0796-0_bb0065","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.surg.2004.06.027","article-title":"Direct peritoneal resuscitation as adjunct to conventional resuscitation from hemorrhagic shock: a better outcome","volume":"136","author":"Garrison","year":"2004","journal-title":"Surgery"},{"key":"10.1007\/s11605-008-0796-0_bb0070","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.amjsurg.2003.07.006","article-title":"A novel method of peritoneal resuscitation improves organ perfusion after hemorrhagic shock","volume":"186","author":"Zakaria","year":"2003","journal-title":"Am J Surg"},{"key":"10.1007\/s11605-008-0796-0_bb0075","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0016-5085(85)80142-6","article-title":"d-Galactosamine hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice","volume":"88","author":"Chojkier","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1007\/s11605-008-0796-0_bb0080","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/hep.1840080420","article-title":"Modulation of hepatotoxicity by macrophages in the liver","volume":"8","author":"Shiratori","year":"1988","journal-title":"Hepatology"},{"key":"10.1007\/s11605-008-0796-0_bb0085","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/jsre.1996.0255","article-title":"Liver endothelial cell dysfunction occurs early following hemorrhagic shock and persists despite crystalloid resuscitation","volume":"63","author":"Wang","year":"1996","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0090","first-page":"187","article-title":"Comparative effects of crystalloid and small volume hypertonic hyperoncotic fluid resuscitation on hepatic microcirculation after hemorrhagic shock","volume":"40","author":"Bauer","year":"1993","journal-title":"Circ Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0095","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1006\/jsre.1998.5426","article-title":"Resuscitation with hypertonic saline dextran reduces endothelial cell swelling and improves hepatic microvascular perfusion and function after hemorrhagic shock","volume":"80","author":"Corso","year":"1998","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0100","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1016\/0024-3205(93)90205-H","article-title":"Hepatic injury and lipid peroxidation during hemorrhagic shock and resuscitation","volume":"53","author":"Dart","year":"1993","journal-title":"Life Sci"},{"key":"10.1007\/s11605-008-0796-0_bb0105","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0022-4804(81)90189-X","article-title":"Liver cell membrane alterations during hemorrhagic shock in the rat","volume":"31","author":"Holliday","year":"1981","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0110","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1097\/00005373-200011000-00015","article-title":"Critical role of oxygen radicals in the initiation of hepatic depression after trauma hemorrhage","volume":"49","author":"Jarrar","year":"2000","journal-title":"J Trauma"},{"key":"10.1007\/s11605-008-0796-0_bb0115","first-page":"350","article-title":"Pentoxifylline restores intestinal microvascular blood flow during resuscitated hemorrhagic shock","volume":"110","author":"Flynn","year":"1991","journal-title":"Surgery"},{"key":"10.1007\/s11605-008-0796-0_bb0120","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/0022-4804(91)90051-M","article-title":"Pentoxifylline but not saralasin restores hepatic blood flow after resuscitation from hemorrhagic shock","volume":"50","author":"Flynn","year":"1991","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0125","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/00024382-199812000-00007","article-title":"Selective microvascular endothelial cell dysfunction in the small intestine following resuscitated hemorrhagic shock","volume":"10","author":"Fruchterman","year":"1998","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0130","first-page":"307","article-title":"Hemorrhage produces depression in microvascular blood flow which persists despite fluid resuscitation","volume":"32","author":"Wang","year":"1990","journal-title":"Circ Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0135","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/00024382-200212000-00014","article-title":"Resuscitation regimens for hemorrhagic shock must contain blood","volume":"18","author":"Zakaria","year":"2002","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0140","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0022-4804(92)90318-T","article-title":"Intestinal blood flow is restored with glutamine or glucose suffusion after hemorrhage","volume":"52","author":"Flynn","year":"1992","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0145","first-page":"11","article-title":"Effect of allopurinol on venous endothelial dysfunction after resuscitated hemorrhagic shock","volume":"1","author":"Flynn","year":"1999","journal-title":"Int J Surg Investig"},{"key":"10.1007\/s11605-008-0796-0_bb0150","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1067\/msy.1998.91489","article-title":"Complement inhibition prevents gut ischemia and endothelial cell dysfunction after hemorrhage\/resuscitation","volume":"124","author":"Fruchterman","year":"1998","journal-title":"Surgery"},{"key":"10.1007\/s11605-008-0796-0_bb0155","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/jsre.1993.1077","article-title":"Endothelial cell dysfunction occurs after hemorrhage in nonheparinized but not in preheparinized models","volume":"54","author":"Wang","year":"1993","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0160","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1006\/jsre.1996.0388","article-title":"Heparan preserves intestinal perfusion after hemorrhage and resuscitation","volume":"66","author":"Watkins","year":"1996","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0165","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/01.shk.0000245017.86117.4e","article-title":"Mechanisms of direct peritoneal resuscitation-mediated splanchnic hyperperfusion following hemorrhagic shock","volume":"27","author":"Zakaria","year":"2007","journal-title":"Shock"},{"key":"10.1007\/s11605-008-0796-0_bb0170","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.surg.2007.08.007","article-title":"Cellular edema regulates tissue capillary perfusion after hemorrhage resuscitation","volume":"142","author":"Zakaria","year":"2007","journal-title":"Surgery"},{"key":"10.1007\/s11605-008-0796-0_bb0175","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jss.2007.04.008","article-title":"Postresuscitation tissue neutrophil infiltration is time-dependent and organ-specific","volume":"143","author":"Zakaria","year":"2007","journal-title":"J Surg Res"},{"key":"10.1007\/s11605-008-0796-0_bb0180","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1152\/jappl.1992.73.4.1467","article-title":"Amiloride-sensitive Na+ pathways in capillary endothelial cell swelling during hemorrhagic shock","volume":"73","author":"Mazzoni","year":"1992","journal-title":"J Appl Physiol"},{"key":"10.1007\/s11605-008-0796-0_bb0185","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.3748\/wjg.v11.i35.5485","article-title":"Functional and morphological changes of the gut barrier during the restitution process after hemorrhagic shock","volume":"11","author":"Chang","year":"2005","journal-title":"World J Gastroenterol"},{"key":"10.1007\/s11605-008-0796-0_bb0190","doi-asserted-by":"crossref","first-page":"G1083","DOI":"10.1152\/ajpgi.00568.2005","article-title":"Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions","volume":"290","author":"Jaeschke","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1007\/s11605-008-0796-0_bb0195","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00005373-199702000-00007","article-title":"Improvement of survival from hemorrhagic shock by enterectomy in rats: finding to implicate the role of the gut for irreversibility of hemorrhagic shock","volume":"42","author":"Chang","year":"1997","journal-title":"J Trauma"},{"key":"10.1007\/s11605-008-0796-0_bb0200","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1097\/00003246-199711000-00018","article-title":"Patterns of cytokine evolution (tumor necrosis factor-alpha and interleukin-6) after septic shock, hemorrhagic shock, and severe trauma","volume":"25","author":"Martin","year":"1997","journal-title":"Crit Care Med"},{"key":"10.1007\/s11605-008-0796-0_bb0205","doi-asserted-by":"crossref","first-page":"G268","DOI":"10.1152\/ajpgi.00313.2006","article-title":"Liver cytokine production and ICAM-1 expression following bone fracture, tissue trauma, and hemorrhage in middle-aged mice","volume":"292","author":"Matsutani","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1007\/s11605-008-0796-0_bb0210","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1097\/00000658-199312000-00011","article-title":"Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure","volume":"218","author":"Roumen","year":"1993","journal-title":"Ann Surg"}],"container-title":["Journal of Gastrointestinal Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11605-008-0796-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11605-008-0796-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1091255X23052393?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1091255X23052393?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11605-008-0796-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T19:31:19Z","timestamp":1761075079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1091255X23052393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S1091255X23052393"],"URL":"https:\/\/doi.org\/10.1007\/s11605-008-0796-0","relation":{},"ISSN":["1091-255X"],"issn-type":[{"value":"1091-255X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemorrhage-Induced Hepatic Injury and Hypoperfusion can be Prevented by Direct Peritoneal Resuscitation","name":"articletitle","label":"Article Title"},{"value":"Journal of Gastrointestinal Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s11605-008-0796-0","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Society for Surgery of the Alimentary Tract. Published by ELSEVIER INC. All rights reserved. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}