{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:42:22Z","timestamp":1784180542749,"version":"3.55.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jgisurgery.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Gastrointestinal Surgery"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1007\/s11605-016-3340-7","type":"journal-article","created":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T12:50:41Z","timestamp":1483447841000},"page":"636-646","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Selective Perioperative Administration of Pasireotide is More Cost-Effective Than Routine Administration for Pancreatic Fistula Prophylaxis"],"prefix":"10.1016","volume":"21","author":[{"given":"Jason W.","family":"Denbo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca S.","family":"Slack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Bruno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan M.","family":"Cloyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Prakash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason B.","family":"Fleming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Aloia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Nicolas","family":"Vauthey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey E.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew H.G.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1007\/s11605-016-3340-7_bb0010","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0039-6060(99)70234-5","article-title":"Effect of hospital volume on in-hospital mortality with pancreaticoduodenectomy","volume":"125","author":"Birkmeyer","year":"1999","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0015","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.gassur.2006.08.018","article-title":"1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience","volume":"10","author":"Winter","year":"2006","journal-title":"J Gastrointest Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0020","doi-asserted-by":"crossref","first-page":"3522","DOI":"10.1245\/s10434-015-4437-z","article-title":"Active Surveillance for Adverse Events Within 90 Days: The Standard for Reporting Surgical Outcomes After Pancreatectomy","volume":"22","author":"Schwarz","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"10.1007\/s11605-016-3340-7_bb0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.surg.2009.12.005","article-title":"Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomy","volume":"148","author":"Gaujoux","year":"2010","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0030","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jamcollsurg.2009.09.020","article-title":"Novel pancreaticojejunostomy with a low rate of anastomotic failure-related complications","volume":"210","author":"Grobmyer","year":"2010","journal-title":"J Am Coll Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0035","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.amjsurg.2008.03.004","article-title":"Life-threatening postoperative pancreatic fistula (grade C) after pancreaticoduodenectomy: incidence, prognosis, and risk factors","volume":"197","author":"Fuks","year":"2009","journal-title":"Am J Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0040","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1477-2574.2009.00051.x","article-title":"Is isolated Roux loop pancreaticojejunostomy superior to conventional reconstruction in pancreaticoduodenectomy?","volume":"11","author":"Perwaiz","year":"2009","journal-title":"HPB (Oxford)"},{"key":"10.1007\/s11605-016-3340-7_bb0045","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1007\/s11605-009-0974-8","article-title":"The role of \u201cfatty pancreas\u201d and of BMI in the occurrence of pancreatic fistula after pancreaticoduodenectomy","volume":"13","author":"Rosso","year":"2009","journal-title":"J Gastrointest Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0050","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00268-007-9388-5","article-title":"Risk prediction for development of pancreatic fistula using the ISGPF classification scheme","volume":"32","author":"Pratt","year":"2008","journal-title":"World J Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0055","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.surg.2005.05.001","article-title":"Postoperative pancreatic fistula: an international study group (ISGPF) definition","volume":"138","author":"Bassi","year":"2005","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0060","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1477-2574.2012.00486.x","article-title":"Toward defining grade C pancreatic fistula following pancreaticoduodenectomy: incidence, risk factors, management and outcome","volume":"14","author":"Denbo","year":"2012","journal-title":"HPB (Oxford)"},{"key":"10.1007\/s11605-016-3340-7_bb0065","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/00000658-199510000-00014","article-title":"A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy","volume":"222","author":"Yeo","year":"1995","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0070","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/00000658-200210000-00004","article-title":"Occlusion of the pancreatic duct versus pancreaticojejunostomy: a prospective randomized trial","volume":"236","author":"Tran","year":"2002","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0075","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/bjs.5000","article-title":"Systematic review and meta-analysis of technique for closure of the pancreatic remnant after distal pancreatectomy","volume":"92","author":"Knaebel","year":"2005","journal-title":"Br J Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0080","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.jamcollsurg.2008.12.031","article-title":"Does type of pancreaticojejunostomy after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institution trial","volume":"208","author":"Berger","year":"2009","journal-title":"J Am Coll Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0085","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0039-6060(03)00345-3","article-title":"Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial","volume":"134","author":"Bassi","year":"2003","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0090","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.gassur.2004.06.011","article-title":"Does fibrin glue sealant decrease the rate of pancreatic fistula after pancreaticoduodenectomy? Results of a prospective randomized trial","volume":"8","author":"Lillemoe","year":"2004","journal-title":"J Gastrointest Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0095","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.gassur.2006.07.020","article-title":"Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trial","volume":"10","author":"Winter","year":"2006","journal-title":"J Gastrointest Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0100","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00000658-200009000-00014","article-title":"Does prophylactic octreotide decrease the rates of pancreatic fistula and other complications after pancreaticoduodenectomy? Results of a prospective randomized placebo-controlled trial","volume":"232","author":"Yeo","year":"2000","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0105","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1097\/00000658-199711000-00008","article-title":"Prospective, randomized trial of octreotide to prevent pancreatic fistula after pancreaticoduodenectomy for malignant disease","volume":"226","author":"Lowy","year":"1997","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0110","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0002-9610(92)90264-R","article-title":"Role of octreotide in the prevention of postoperative complications following pancreatic resection","volume":"163","author":"Buchler","year":"1992","journal-title":"Am J Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0115","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0039-6060(05)80225-9","article-title":"Efficacy of octreotide in the prevention of pancreatic fistula after elective pancreatic resections: a prospective, controlled, randomized clinical trial","volume":"117","author":"Montorsi","year":"1995","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0120","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1046\/j.1365-2168.2001.01659.x","article-title":"Somatostatin and octreotide in the prevention of postoperative pancreatic complications and the treatment of enterocutaneous pancreatic fistulas: a systematic review of randomized controlled trials","volume":"88","author":"Li-Ling","year":"2001","journal-title":"Br J Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0125","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S1072-7515(03)00104-2","article-title":"The potent somatostatin analogue vapreotide does not decrease pancreas-specific complications after elective pancreatectomy: a prospective, multicenter, double-blinded, randomized, placebo-controlled trial","volume":"196","author":"Pancreatic Surgery G.","year":"2003","journal-title":"J Am Coll Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0130","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1530\/eje.0.1460707","article-title":"SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile","volume":"146","author":"Bruns","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"10.1007\/s11605-016-3340-7_bb0135","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1056\/NEJMoa1313688","article-title":"Pasireotide for postoperative pancreatic fistula","volume":"370","author":"Allen","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1007\/s11605-016-3340-7_bb0140","doi-asserted-by":"crossref","unstructured":"Ma LW, Dominguez-Rosado I, Gennarelli RL, et al. The Cost of Postoperative Pancreatic Fistula Versus the Cost of Pasireotide: Results from a Prospective Randomized Trial. Ann Surg 2016.","DOI":"10.1097\/SLA.0000000000001892"},{"key":"10.1007\/s11605-016-3340-7_bb0145","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/jso.24239","article-title":"Prophylactic pasireotide administration following pancreatic resection reduces cost while improving outcomes","volume":"113","author":"Abbott","year":"2016","journal-title":"J Surg Oncol"},{"key":"10.1007\/s11605-016-3340-7_bb0150","doi-asserted-by":"crossref","unstructured":"Goyert N, Eeson G, Kagedan DJ, et al. Pasireotide for the Prevention of Pancreatic Fistula Following Pancreaticoduodenectomy: A Cost-effectiveness Analysis. Ann Surg 2016.","DOI":"10.1016\/j.hpb.2016.03.105"},{"key":"10.1007\/s11605-016-3340-7_bb0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jamcollsurg.2012.09.002","article-title":"A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy","volume":"216","author":"Callery","year":"2013","journal-title":"J Am Coll Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0160","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/j.1477-2574.2010.00239.x","article-title":"A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively","volume":"12","author":"Wellner","year":"2010","journal-title":"HPB (Oxford)"},{"key":"10.1007\/s11605-016-3340-7_bb0165","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1245\/s10434-011-1594-6","article-title":"Preoperative factors predict perioperative morbidity and mortality after pancreaticoduodenectomy","volume":"18","author":"Greenblatt","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"10.1007\/s11605-016-3340-7_bb0170","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.jamcollsurg.2015.05.011","article-title":"Clinical Risk Score to Predict Pancreatic Fistula after Pancreatoduodenectomy: Independent External Validation for Open and Laparoscopic Approaches","volume":"221","author":"Shubert","year":"2015","journal-title":"J Am Coll Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0175","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1245\/s10434-008-9833-1","article-title":"Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer","volume":"15","author":"Hwang","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1007\/s11605-016-3340-7_bb0180","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s11605-011-1748-7","article-title":"Effect of neoadjuvant chemoradiation and surgical technique on recurrence of localized pancreatic cancer","volume":"16","author":"Katz","year":"2012","journal-title":"J Gastrointest Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0185","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1001\/jama.291.20.2441","article-title":"Prognostic importance of comorbidity in a hospital-based cancer registry","volume":"291","author":"Piccirillo","year":"2004","journal-title":"JAMA"},{"key":"10.1007\/s11605-016-3340-7_bb0190","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.surg.2007.05.005","article-title":"Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0195","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.surg.2007.02.001","article-title":"Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"10.1007\/s11605-016-3340-7_bb0200","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/01.sla.0000251708.70219.d2","article-title":"Clinical and economic validation of the International Study Group of Pancreatic Fistula (ISGPF) classification scheme","volume":"245","author":"Pratt","year":"2007","journal-title":"Ann Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0205","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00423-010-0719-x","article-title":"A grading system can predict clinical and economic outcomes of pancreatic fistula after pancreaticoduodenectomy: results in 755 consecutive patients","volume":"396","author":"Daskalaki","year":"2011","journal-title":"Langenbecks Arch Surg"},{"key":"10.1007\/s11605-016-3340-7_bb0210","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1499-3872(13)60084-3","article-title":"Clinical and economic consequences of pancreatic fistula after elective pancreatic resection","volume":"12","author":"Cecka","year":"2013","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1007\/s11605-016-3340-7_bb0215","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/S0140-6736(11)60237-7","article-title":"Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial","volume":"377","author":"Diener","year":"2011","journal-title":"Lancet"}],"container-title":["Journal of Gastrointestinal Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11605-016-3340-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11605-016-3340-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1091255X23026161?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1091255X23026161?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11605-016-3340-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T19:51:33Z","timestamp":1761076293000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1091255X23026161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S1091255X23026161"],"URL":"https:\/\/doi.org\/10.1007\/s11605-016-3340-7","relation":{},"ISSN":["1091-255X"],"issn-type":[{"value":"1091-255X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selective Perioperative Administration of Pasireotide is More Cost-Effective Than Routine Administration for Pancreatic Fistula Prophylaxis","name":"articletitle","label":"Article Title"},{"value":"Journal of Gastrointestinal Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s11605-016-3340-7","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Society for Surgery of the Alimentary Tract. Published by ELSEVIER INC. All rights reserved. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}