{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T15:24:43Z","timestamp":1760369083119},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T00:00:00Z","timestamp":1337212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2012,5,17]],"date-time":"2012-05-17T00:00:00Z","timestamp":1337212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J GEN INTERN MED"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s11606-012-2089-2","type":"journal-article","created":{"date-parts":[[2012,5,16]],"date-time":"2012-05-16T11:32:17Z","timestamp":1337167937000},"page":"1722-1725","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Cardiac Complications of Unwitting Co-injection of Quinine\/Quinidine with Heroin in an Intravenous Drug User"],"prefix":"10.1007","volume":"27","author":[{"given":"Karran A.","family":"Phillips","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn A.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzie L.","family":"Preston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,5,17]]},"reference":[{"key":"2089_CR1","unstructured":"Kelley's Textbook of Internal Medicine. 4th ed: Lippincott Williams & Wilkins; 2000."},{"key":"2089_CR2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/dta.220","volume":"3","author":"C Cole","year":"2011","unstructured":"Cole C, Jones L, McVeigh J, Kicman A, Syed Q, Bellis M. Adulterants in illicit drugs: a review of empirical evidence. Drug Test Anal. 2011;3:89\u201396.","journal-title":"Drug Test Anal"},{"key":"2089_CR3","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1081\/CLT-100102008","volume":"38","author":"RJ Hamilton","year":"2000","unstructured":"Hamilton RJ, Perrone J, Hoffman R, et al. A descriptive study of an epidemic of poisoning caused by heroin adulterated with scopolamine. J Toxicol Clin Toxicol. 2000;38:597\u2013608.","journal-title":"J Toxicol Clin Toxicol"},{"key":"2089_CR4","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1081\/CLT-100102441","volume":"37","author":"J Perrone","year":"1999","unstructured":"Perrone J, Shaw L, De Roos F. Laboratory confirmation of scopolamine co-intoxication in patients using tainted heroin. J Toxicol Clin Toxicol. 1999;37:491\u20136.","journal-title":"J Toxicol Clin Toxicol"},{"key":"2089_CR5","first-page":"793","volume":"54","author":"Centers for Disease Control and Prevention","year":"2005","unstructured":"Centers for Disease Control and Prevention. Atypical reactions associated with heroin use-Five states, January-April 2005. MMWR. 2005;54:793\u20136.","journal-title":"MMWR"},{"key":"2089_CR6","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S0378-4274(99)00270-2","volume":"114","author":"G Brambilla","year":"2000","unstructured":"Brambilla G, Cenci T, Franconi F, et al. Clinical and pharmacological profile in a clenbuterol epidemic poisoning of contaminated beef meat in Italy. Toxicol Lett. 2000;114:47\u201353.","journal-title":"Toxicol Lett"},{"key":"2089_CR7","first-page":"1381","volume":"58","author":"Centers for Disease Control and Prevention (CDC)","year":"2009","unstructured":"Centers for Disease Control and Prevention (CDC). Agranulocytosis associated with cocaine use\u2014four States, March 2008-November 2009. MMWR Morb Mortal Wkly Rep. 2009;58:1381\u20135.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2089_CR8","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1038\/clpt.2010.156","volume":"88","author":"A Chang","year":"2010","unstructured":"Chang A, Osterloh J, Thomas J. Levamisole: A Dangerous New Cocaine Adulterant. Clin Pharmacol Ther. 2010;88:408\u201311.","journal-title":"Clin Pharmacol Ther"},{"key":"2089_CR9","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1177\/014107688007300311","volume":"73","author":"JD Kirby","year":"1980","unstructured":"Kirby JD, Black M, McGibbon D. Levamisole-induced lichenoid eruptions. J R Soc Med. 1980;73:208\u201311.","journal-title":"J R Soc Med"},{"key":"2089_CR10","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1159\/000329436","volume":"223","author":"I de la Hera","year":"2011","unstructured":"de la Hera I, Sanz V, Cullen D, et al. Necrosis of ears after use of cocaine probably adulterated with levamisole. Dermatology. 2011;223:25\u20138.","journal-title":"Dermatology"},{"key":"2089_CR11","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1002\/dta.75","volume":"1","author":"AA Savaliya","year":"2009","unstructured":"Savaliya AA, Prasad B, Raijada DK, Singh S. Detection and characterization of synthetic steroidal and non-steroidal anti-inflammatory drugs in Indian ayurvedic\/herbal products using LC-MS\/TOF. Drug Test Anal. 2009;1:372\u201381.","journal-title":"Drug Test Anal"},{"key":"2089_CR12","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/j.1755-5922.2010.00193.x","volume":"28","author":"PA Cohen","year":"2010","unstructured":"Cohen PA, Ernst E. Safety of Herbal Supplements: A Guide for Cardiologists. Cardiovasc Ther. 2010;28:246\u201353.","journal-title":"Cardiovasc Ther"},{"key":"2089_CR13","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/S0099-1767(97)90145-8","volume":"23","author":"JM Dillmann","year":"1997","unstructured":"Dillmann JM. Bogus heroin. J Emerg Nurs. 1997;23:457\u20139.","journal-title":"J Emerg Nurs"},{"key":"2089_CR14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1177\/106002809502900107","volume":"29","author":"SM Bhavnani","year":"1995","unstructured":"Bhavnani SM, Preston SL. Monitoring of intravenous quinidine infusion in the treatment of Plasmodium-falciparum malaria. Ann Pharmacother. 1995;29:33\u20135.","journal-title":"Ann Pharmacother"},{"key":"2089_CR15","doi-asserted-by":"publisher","first-page":"2944","DOI":"10.1161\/01.CIR.92.10.2944","volume":"92","author":"R Sheldon","year":"1995","unstructured":"Sheldon R, Duff H, Koshman ML. Antiarrhythmic activity of quinine in humans. Circulation. 1995;92:2944\u201350.","journal-title":"Circulation"},{"key":"2089_CR16","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1111\/j.1365-2125.1993.tb04165.x","volume":"35","author":"J Karbwang","year":"1993","unstructured":"Karbwang J, Davis TME, Looareesuwan S, Molunto P, Bunnag D, White NJ. A comparison of the pharmokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males. Br J Clin Pharmacol. 1993;35:265\u201371.","journal-title":"Br J Clin Pharmacol"},{"key":"2089_CR17","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1097\/00005344-198303000-00001","volume":"5","author":"NJ White","year":"1983","unstructured":"White NJ, Looareesuwan S, Warrell DA. Quinine and quinidine\u2014A comparison of ECG effects during the treatment of malaria. J Cardiovasc Pharmacol. 1983;5:173\u20135.","journal-title":"J Cardiovasc Pharmacol"},{"key":"2089_CR18","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1056\/NEJM198505163122001","volume":"312","author":"RE Phillips","year":"1985","unstructured":"Phillips RE, Warrell DA, White NJ, Looareesuwan S, Karbwang J. Intravenous quinidine for the treatment of severe Falciparum-malaria\u2014Clinical and Pharmokinetic studies. New Engl J Med. 1985;312:1273\u20138.","journal-title":"New Engl J Med"},{"key":"2089_CR19","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S1473-3099(07)70187-1","volume":"7","author":"NJ White","year":"2007","unstructured":"White NJ. Cardiotoxicity of antimalarial drugs. Lancet Infect Dis. 2007;7:549\u201358.","journal-title":"Lancet Infect Dis"},{"key":"2089_CR20","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1056\/NEJM199801013380107","volume":"338","author":"AA Grace","year":"1998","unstructured":"Grace AA, Camm J. Quinidine. New Engl J Med. 1998;338:35\u201345.","journal-title":"New Engl J Med"},{"key":"2089_CR21","unstructured":"Roxane. Methadone Hydrochloride Tablets USP [package insert]. Columbus, OH: Roxane Laboratories Inc.; Revised October 2006."},{"key":"2089_CR22","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1111\/j.1465-3362.2010.00213.x","volume":"30","author":"B Butler","year":"2011","unstructured":"Butler B, Rubin G, Lawrance A, Batey R, Bell J. Estimating the risk of fatal arrhythmia in patients in methadone maintenance treatment for heroin addiction. Drug Alcohol Rev. 2011;30:173\u201380.","journal-title":"Drug Alcohol Rev"},{"key":"2089_CR23","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1111\/j.1465-3362.2010.00237.x","volume":"30","author":"S Mayet","year":"2011","unstructured":"Mayet S, Gossop M, Lintzeris N, Markides V, Strang J. Methadone maintenance, QTc and torsade de pointes: Who needs an electrocardiogram and what is the prevalence of QTc prolongation? Drug Alcohol Rev. 2011;30:388\u201396.","journal-title":"Drug Alcohol Rev"}],"container-title":["Journal of General Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11606-012-2089-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11606-012-2089-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11606-012-2089-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11606-012-2089-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T10:08:16Z","timestamp":1659089296000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11606-012-2089-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,17]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["2089"],"URL":"https:\/\/doi.org\/10.1007\/s11606-012-2089-2","relation":{},"ISSN":["0884-8734","1525-1497"],"issn-type":[{"value":"0884-8734","type":"print"},{"value":"1525-1497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,17]]},"assertion":[{"value":"28 September 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2012","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2012","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2012","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}