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Dr. Campbell, Dr. Hechter, and Mr. Ray have received research support to their institution from the Industry PMR Consortium, a consortium of companies working together to conduct post marketing studies required by the Food and Drug Administration that assesses risks related to opioid analgesic use. Dr. Andrade has received research support on grants to the University of Massachusetts Chan Medical School from Pfizer, Inc, and GlaxoSmithKline. Dr. Binswanger receives royalties from UpToDate (Wolters-Kluwer). The remaining authors report no conflict of interest (please see individual statements of each author). Ms. Rosa was substantially involved in the study, consistent with her role as Scientific Officer. She had no substantial involvement in the other cited grants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The views and opinions expressed in this manuscript are those of the authors only and do not necessarily represent the views, official policy, or position of the U.S. Department of Health and Human Services or any of its affiliated institutions or agencies.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}