{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:08:06Z","timestamp":1792728486930,"version":"4.5.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J GEN INTERN MED"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s11606-025-09772-4","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T21:53:37Z","timestamp":1753739617000},"page":"18-25","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical Decision Support to Increase Naloxone Co-prescribing from the Inpatient Setting"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1553-3363","authenticated-orcid":false,"given":"Jacob A.","family":"Lebin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlin","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy E.","family":"Trinkley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Calcaterra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixin","family":"Lun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Hensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason A.","family":"Hoppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,28]]},"reference":[{"key":"9772_CR1","doi-asserted-by":"publisher","first-page":"202","DOI":"10.15585\/mmwr.mm7006a4","volume":"70","author":"CL Mattson","year":"2021","unstructured":"Mattson CL, Tanz LJ, Quinn K, Kariisa M, Patel P, Davis NL. Trends and Geographic Patterns in Drug and Synthetic Opioid Overdose Deaths \u2014 United States, 2013\u20132019. MMWR Morb Mortal Wkly Rep 2021;70:202\u2013207.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"9772_CR2","unstructured":"Centers for Disease Control and Prevention. U.S. Overdose Deaths Decrease in 2023, First Time Since 2018. https:\/\/www.cdc.gov\/nchs\/pressroom\/nchs_press_releases\/2024\/20240515.htm"},{"key":"9772_CR3","unstructured":"Wide-ranging online data for epidemiologic research (WONDER). Atlanta, GA: CDC, National Center for Health Statistics; 2022."},{"issue":"4","key":"9772_CR4","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1097\/ADM.0000000000000915","volume":"16","author":"C King","year":"2022","unstructured":"King C, Cook R, Korthuis PT, Morris CD, Englander H. Causes of death in the 12 months after hospital discharge among patients with opioid use disorder. Journal of addiction medicine. 2022;16(4):466-9.","journal-title":"J Addict Med"},{"issue":"3","key":"9772_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15585\/mmwr.rr7103a1","volume":"71","author":"D Dowell","year":"2022","unstructured":"Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC clinical practice guideline for prescribing opioids for pain\u2014United States, 2022. MMWR Recommendations and Reports. 2022;71(3):1.","journal-title":"MMWR Recomm Rep"},{"key":"9772_CR6","doi-asserted-by":"publisher","first-page":"f174","DOI":"10.1136\/bmj.f174","volume":"346","author":"AY Walley","year":"2013","unstructured":"Walley AY, Xuan Z, Hackman HH, et al. Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis. Bmj. 2013;346.","journal-title":"Bmj"},{"issue":"1","key":"9772_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7326\/0003-4819-158-1-201301010-00003","volume":"158","author":"PO Coffin","year":"2013","unstructured":"Coffin PO, Sullivan SD. Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal. Annals of internal medicine. 2013;158(1):1-9.","journal-title":"Ann Intern Med"},{"issue":"1","key":"9772_CR8","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12954-022-00677-7","volume":"19","author":"M Lowenstein","year":"2022","unstructured":"Lowenstein M, Sangha HK, Spadaro A, Perrone J, Delgado MK, Agarwal AK. Patient perspectives on naloxone receipt in the emergency department: a qualitative exploration. Harm Reduction Journal. 2022;19(1):97.","journal-title":"Harm Reduct J"},{"issue":"31","key":"9772_CR9","doi-asserted-by":"publisher","first-page":"679","DOI":"10.15585\/mmwr.mm6831e1","volume":"68","author":"GP Guy Jr","year":"2019","unstructured":"Guy Jr GP, Haegerich TM, Evans ME, Losby JL, Young R, Jones CM. Vital signs: pharmacy-based naloxone dispensing\u2014United States, 2012\u20132018. Morbidity and Mortality Weekly Report. 2019;68(31):679.","journal-title":"Morb Mortal Wkly Rep"},{"issue":"S 01","key":"9772_CR10","doi-asserted-by":"publisher","first-page":"S103","DOI":"10.15265\/IYS-2016-s034","volume":"25","author":"B Middleton","year":"2016","unstructured":"Middleton B, Sittig DF, Wright A. Clinical decision support: a 25 year retrospective and a 25 year vision. Yearbook of medical informatics. 2016;25(S 01):S103-16.","journal-title":"Yearb Med Inform"},{"key":"9772_CR11","first-page":"1","volume":"13","author":"S Van de Velde","year":"2018","unstructured":"Van de Velde S, Kunnamo I, Roshanov P, et al. The GUIDES checklist: development of a tool to improve the successful use of guideline-based computerised clinical decision support. Implementation Science. 2018;13:1-2.","journal-title":"Implement Sci"},{"key":"9772_CR12","doi-asserted-by":"publisher","first-page":"m3216","DOI":"10.1136\/bmj.m3216","volume":"370","author":"JL Kwan","year":"2020","unstructured":"Kwan JL, Lo L, Ferguson J, et al. Computerised clinical decision support systems and absolute improvements in care: meta-analysis of controlled clinical trials. BMJ 2020; 370: m3216.","journal-title":"BMJ"},{"issue":"3","key":"9772_CR13","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/ADM.0000000000001102","volume":"17","author":"JK Srikumar","year":"2023","unstructured":"Srikumar JK, Daniel K, Balasanova AA. Implementation of a Naloxone Best Practice Advisory Into an Electronic Health Record. J Addict Med. 2023;17(3):346-348. https:\/\/doi.org\/10.1097\/ADM.0000000000001102.","journal-title":"J Addict Med"},{"issue":"1","key":"9772_CR14","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s11606-016-3810-3","volume":"32","author":"RA Deyo","year":"2017","unstructured":"Deyo RA, Hallvik SE, Hildebran C, et al. Association Between Initial Opioid Prescribing Patterns and Subsequent Long-Term Use Among Opioid-Na\u00efve Patients: A Statewide Retrospective Cohort Study. J Gen Intern Med. 2017;32(1):21-27. https:\/\/doi.org\/10.1007\/s11606-016-3810-3.","journal-title":"J Gen Intern Med"},{"key":"9772_CR15","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1007\/s11606-015-3539-4","volume":"31","author":"SL Calcaterra","year":"2016","unstructured":"Calcaterra SL, Yamashita TE, Min SJ, Keniston A, Frank JW, Binswanger IA. Opioid prescribing at hospital discharge contributes to chronic opioid use. Journal of general internal medicine. 2016;31:478-85.","journal-title":"J Gen Intern Med"},{"issue":"10","key":"9772_CR16","doi-asserted-by":"publisher","first-page":"e19676","DOI":"10.2196\/19676","volume":"22","author":"KE Trinkley","year":"2020","unstructured":"Trinkley KE, Kahn MG, Bennett TD, et al. Integrating the practical robust implementation and sustainability model with best practices in clinical decision support design: implementation science approach. Journal of Medical Internet Research. 2020;22(10):e19676.","journal-title":"J Med Internet Res"},{"key":"9772_CR17","doi-asserted-by":"publisher","first-page":"e297","DOI":"10.1371\/journal.pmed.0040297","volume":"4","author":"JP Vandenbroucke","year":"2007","unstructured":"Vandenbroucke JP, Von Elm E, Altman DG, et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PLoS Med 2007;4:e297 .","journal-title":"PLoS Med"},{"issue":"7","key":"9772_CR18","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1093\/jamia\/ocad083","volume":"30","author":"MZ Raban","year":"2023","unstructured":"Raban MZ, Gates PJ, Gamboa S, Gonzalez G, Westbrook JI. Effectiveness of non-interruptive nudge interventions in electronic health records to improve the delivery of care in hospitals: a systematic review. Journal of the American Medical Informatics Association. 2023;30(7):1313-22.","journal-title":"J Am Med Inform Assoc"},{"issue":"7","key":"9772_CR19","first-page":"e63919","volume":"16","author":"E Cramer","year":"2024","unstructured":"Cramer E, Kuperman E, Meyer N, Blum J. Improving Naloxone Co-prescribing Through Clinical Decision Support. Cureus. 2024;16(7).","journal-title":"Cureus"},{"issue":"1","key":"9772_CR20","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1213\/ANE.0000000000005976","volume":"135","author":"SD Nelson","year":"2022","unstructured":"Nelson SD, McCoy AB, Rector H, et al. Assessment of a naloxone coprescribing alert for patients at risk of opioid overdose: a quality improvement project. Anesthesia & Analgesia. 2022;135(1):26-34.","journal-title":"Anesth Analg"},{"issue":"5","key":"9772_CR21","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1002\/jhm.12825","volume":"17","author":"CE Ronan","year":"2022","unstructured":"Ronan CE, Crable EL, Drainoni ML, Walkey AJ. The impact of clinical decision support systems on provider behavior in the inpatient setting: A systematic review and meta\u2010analysis. Journal of Hospital Medicine. 2022;17(5):368-83.","journal-title":"J Hosp Med"},{"issue":"4","key":"9772_CR22","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1136\/jamia.2009.000695","volume":"17","author":"BL Strom","year":"2010","unstructured":"Strom BL, Schinnar R, Bilker W, Hennessy S, Leonard CE, Pifer E. Randomized clinical trial of a customized electronic alert requiring an affirmative response compared to a control group receiving a commercial passive CPOE alert: NSAID\u2014warfarin co-prescribing as a test case. Journal of the American Medical Informatics Association. 2010;17(4):411-5.","journal-title":"J Am Med Inform Assoc"},{"key":"9772_CR23","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s11606-012-1994-8","volume":"27","author":"MA Boustani","year":"2012","unstructured":"Boustani MA, Campbell NL, Khan BA, et al. Enhancing care for hospitalized older adults with cognitive impairment: a randomized controlled trial. Journal of general internal medicine. 2012;27:561-7.","journal-title":"J Gen Intern Med"},{"issue":"3","key":"9772_CR24","doi-asserted-by":"publisher","first-page":"257","DOI":"10.4037\/ajcc2013447","volume":"22","author":"BA Khan","year":"2013","unstructured":"Khan BA, Calvo-Ayala E, Campbell N, et al. Clinical decision support system and incidence of delirium in cognitively impaired older adults transferred to intensive care. American Journal of Critical Care. 2013;22(3):257-62.","journal-title":"Am J Crit Care"},{"issue":"17","key":"9772_CR25","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1001\/archinternmed.2010.324","volume":"170","author":"BL Strom","year":"2010","unstructured":"Strom BL, Schinnar R, Aberra F, Bilker W, Hennessy S, Leonard CE, Pifer E. Unintended effects of a computerized physician order entry nearly hard-stop alert to prevent a drug interaction: a randomized controlled trial. Archives of internal medicine. 2010;170(17):1578-83.","journal-title":"Arch Intern Med"},{"key":"9772_CR26","doi-asserted-by":"publisher","DOI":"10.4324\/9781498757461","volume-title":"Improving outcomes with clinical decision support: an implementer\u2019s guide","author":"J Osheroff","year":"2012","unstructured":"Osheroff J, Teich J, Levick D, et al. Improving Outcomes with Clinical Decision Support: An Implementer\u2019s Guide, Second Edition. Boca Raton, FL.: HIMSS Publishing; 2012","edition":"2"},{"issue":"1","key":"9772_CR27","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12954-023-00736-7","volume":"20","author":"MR Khan","year":"2023","unstructured":"Khan MR, Hoff L, Elliott L, et al. Racial\/ethnic disparities in opioid overdose prevention: comparison of the naloxone care cascade in White, Latinx, and Black people who use opioids in New York City. Harm Reduction Journal. 2023;20(1):24.","journal-title":"Harm Reduct J"},{"issue":"1","key":"9772_CR28","doi-asserted-by":"publisher","first-page":"0","DOI":"10.1136\/bmjhci-2019-000015","volume":"26","author":"KE Trinkley","year":"2019","unstructured":"Trinkley KE, Blakeslee WW, Matlock DD, et al. Clinician preferences for computerised clinical decision support for medications in primary care: a focus group study. BMJ health & care informatics. 2019;26(1).","journal-title":"BMJ Health Care Inform"},{"issue":"7","key":"9772_CR29","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1007\/s11606-023-08580-y","volume":"39","author":"AM Maw","year":"2024","unstructured":"Maw AM, Trinkley KE, Glasgow RE. The Role of Pragmatic Implementation Science Methods in Achieving Equitable and Effective Use of Artificial Intelligence in Healthcare. Journal of General Internal Medicine. 2024;39(7):1242-4.","journal-title":"J Gen Intern Med"},{"key":"9772_CR30","doi-asserted-by":"publisher","first-page":"E02","DOI":"10.5888\/pcd15.170271","volume":"15","author":"RE Glasgow","year":"2018","unstructured":"Glasgow RE, Estabrooks PE. Peer reviewed: Pragmatic applications of RE-AIM for health care initiatives in community and clinical settings. Preventing chronic disease. 2018;15.","journal-title":"Prev Chronic Dis"},{"key":"9772_CR31","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1001\/jama.2024.4088","volume":"332","author":"DC Angus","year":"2024","unstructured":"Angus DC, Huang AJ, Lewis RJ, et al. The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided. JAMA. 2024.","journal-title":"JAMA"},{"issue":"3","key":"9772_CR32","doi-asserted-by":"publisher","first-page":"381","DOI":"10.5811\/westjem.2015.2.24909","volume":"16","author":"K Dwyer","year":"2015","unstructured":"Dwyer K, Walley AY, Langlois BK, et al. Opioid education and nasal naloxone rescue kits in the emergency department. West J Emerg Med. 2015;16(3):381\u20134.","journal-title":"West J Emerg Med"},{"issue":"3","key":"9772_CR33","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1136\/injuryprev-2017-042676","volume":"25","author":"CJ Banta-Green","year":"2019","unstructured":"Banta-Green CJ, Coffin PO, Merrill JO, et al. Impacts of an opioid overdose preventionintervention delivered subsequent to acute care. Inj Prev. 2019;25(3):191\u20138.","journal-title":"Inj Prev"},{"issue":"2","key":"9772_CR34","doi-asserted-by":"publisher","first-page":"S154","DOI":"10.1016\/j.japh.2017.01.002","volume":"57","author":"J Devries","year":"2017","unstructured":"Devries J, Rafie S, Polston G. Implementing an overdose education and naloxone distribution program in a health system. Journal of the American Pharmacists Association. 2017;57(2):S154-60.","journal-title":"J Am Pharm Assoc"},{"key":"9772_CR35","doi-asserted-by":"publisher","first-page":"100244","DOI":"10.1016\/j.dadr.2024.100244","volume":"28","author":"SG Weiner","year":"2024","unstructured":"Weiner SG, Miller EN, Burke B, Clear B. Naloxone prescription fills and use by patients treated for opioid use disorder by telehealth. Drug and Alcohol Dependence Reports. 2024;28:100244.","journal-title":"Drug Alcohol Depend Rep"},{"key":"9772_CR36","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1001\/jama.2024.8378","volume":"332","author":"KP Chua","year":"2024","unstructured":"Chua KP, Conti RM, Lagisetty P, Bohnert AS, He S, Nguyen TD. Association Between Cost Sharing and Naloxone Prescription Dispensing. JAMA. 2024.","journal-title":"JAMA."},{"issue":"2","key":"9772_CR37","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1080\/08897077.2019.1686721","volume":"41","author":"EF Madden","year":"2020","unstructured":"Madden EF, Qeadan F. Racial inequities in US naloxone prescriptions. Substance Abuse. 2020;41(2):232-44.","journal-title":"Subst Abuse"},{"issue":"7","key":"9772_CR38","doi-asserted-by":"publisher","first-page":"e2116860","DOI":"10.1001\/jamanetworkopen.2021.16860","volume":"4","author":"JE Goldstick","year":"2021","unstructured":"Goldstick JE, Guy GP, Losby JL, Baldwin G, Myers M, Bohnert AS. Changes in initial opioid prescribing practices after the 2016 release of the CDC guideline for prescribing opioids for chronic pain. JAMA network open. 2021;4(7):e2116860.","journal-title":"JAMA Netw Open"}],"container-title":["Journal of General Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11606-025-09772-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11606-025-09772-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11606-025-09772-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:01:55Z","timestamp":1785196915000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11606-025-09772-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["9772"],"URL":"https:\/\/doi.org\/10.1007\/s11606-025-09772-4","relation":{},"ISSN":["0884-8734","1525-1497"],"issn-type":[{"value":"0884-8734","type":"print"},{"value":"1525-1497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]},"assertion":[{"value":"4 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Human Ethics and Consent to Participate Declarations:","group":{"name":"EthicsHeading","label":"Declarations:"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Conflict of Interest:","group":{"name":"EthicsHeading","label":"Declarations:"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}