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However, there is little data to inform PRx dose recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify how PRx dose affects benefit redemption, food security, and fruit\/vegetable (FV) intake.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Three-arm, prospective randomized community trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Adult clients of a community-based nonprofit social service provider.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Monthly electronic distribution of $40, $80, or $110 (equivalent to 10%, 20%, or 30% of the FV component of the USDA Thrifty Food Plan) for 6\u00a0months, redeemable at major grocery stores only for FV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Measures<\/jats:title>\n                    <jats:p>Primary (benefit redemption) and secondary (food security and FV intake) outcomes were assessed at 3 months (primary endpoint) and 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      Study participants (\n                      <jats:italic>n\u2009<\/jats:italic>\n                      =\u2009242) were randomized to $40 (\n                      <jats:italic>n\u2009<\/jats:italic>\n                      =\u200981), $80 (\n                      <jats:italic>n\u2009<\/jats:italic>\n                      =\u200980), or $110 (\n                      <jats:italic>n\u2009<\/jats:italic>\n                      =\u200981) PRx arms. Mean (SD) age was 35.16 (9.45) years and 235 (97.1%) self-identified as female and 200 (82.6%) as Hispanic. Overall, there appeared to be a dose-response relationship with progressively greater benefit redemption rate, food security, and FV consumption as PRx dose increased. Compared with $40, the $110 PRx dose significantly improved food insecurity (\n                      <jats:italic>p\u2009<\/jats:italic>\n                      =\u20090.01) and FV intake (\n                      <jats:italic>p\u2009<\/jats:italic>\n                      =\u20090.03) at 3\u00a0months, and the benefit redemption rate (\n                      <jats:italic>p\u2009<\/jats:italic>\n                      =\u20090.04) at 6\u00a0months. At 3\u00a0months, the benefit redemption rate was 60.2% (95%CI 51.9\u201368.6%) $40 group, 67.6% (95%CI 59.9\u201375.3%) $80 group, and 70.4% (95%CI 63.0\u201377.9%) $110 group. Food insecurity was reported for 74.3% (95%CI 62.0\u201386.6%) $40 group, 66.2% (95%CI 50.1\u201382.2%) $80 group, and 47.4% (95%CI 31.6\u201363.1%) $110 group. Mean FV consumption in cups\/day was 2.51 (95%CI 2.31\u20132.72) $40 group, 2.66 (95%CI 2.38\u20132.95) $80 group, and 2.89 (95%CI 2.61\u20133.17) $110 group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher PRx dose increased benefit redemption, food security, and FV consumption, especially when comparing the $110 and $40 doses. Dose is an important design element to improve PRx redemption levels and potentially PRx-related health outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11606-026-10773-0","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:04:34Z","timestamp":1789488274000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Produce Prescription Dose Response: A Randomized Community Trial"],"prefix":"10.1007","author":[{"given":"Ryan M.","family":"Kane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximena","family":"Perez-Velazco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronli","family":"Levi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlena","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Mehri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilary K.","family":"Seligman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth A.","family":"Berkowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"10773_CR1","doi-asserted-by":"publisher","unstructured":"Seligman HK, Angell SY, Berkowitz SA, et al. 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