{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:03:55Z","timestamp":1792796635166,"version":"4.5.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T00:00:00Z","timestamp":1398988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2014,5,2]],"date-time":"2014-05-02T00:00:00Z","timestamp":1398988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["In Vitro Cell.Dev.Biol.-Animal"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1007\/s11626-014-9763-0","type":"journal-article","created":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T18:43:32Z","timestamp":1398969812000},"page":"731-739","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Nicotine inhibits the proliferation by upregulation of nitric oxide and increased HDAC1 in mouse neural stem cells"],"prefix":"10.1007","volume":"50","author":[{"given":"Hanbyeol","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Ran","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungwon","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunjeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok-Ho","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heung-Myong","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Min","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Joon","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Min","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Ran","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,5,2]]},"reference":[{"key":"9763_CR1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.neulet.2012.12.046","volume":"535","author":"D Brown","year":"2013","unstructured":"Brown D, Ramlochansingh C, Manaye KF, Tizabi Y (2013) Nicotine promotes survival of cells expressing amyloid precursor protein and presenilin: implication for Alzheimer\u2019s disease. Neurosci Lett 535:57\u201361","journal-title":"Neurosci Lett"},{"key":"9763_CR2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.abb.2010.05.003","volume":"501","author":"S Chung","year":"2010","unstructured":"Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I (2010) Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys 501:79\u201390","journal-title":"Arch Biochem Biophys"},{"key":"9763_CR3","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1139\/H08-147","volume":"34","author":"S Das","year":"2009","unstructured":"Das S, Gautam N, Dey SK, Maiti T, Roy S (2009) Oxidative stress in the brain of nicotine-induced toxicity: protective role of Andrographis paniculata Nees and vitamin E. Appl Physiol Nutr Metab = Physiol Appl Nutr Metab 34:124\u2013135","journal-title":"Appl Physiol Nutr Metab = Physiol Appl Nutr Metab"},{"key":"9763_CR4","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/1423-0127-18-48","volume":"18","author":"HS Go","year":"2011","unstructured":"Go HS, Seo JE, Kim KC, Han SM, Kim P, Kang YS, Han SH, Shin CY, Ko KH (2011) Valproic acid inhibits neural progenitor cell death by activation of NF-kappaB signaling pathway and up-regulation of Bcl-XL. J Biomed Sci 18:48","journal-title":"J Biomed Sci"},{"key":"9763_CR5","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S0165-6147(02)01893-X","volume":"23","author":"BT Hawkins","year":"2002","unstructured":"Hawkins BT, Brown RC, Davis TP (2002) Smoking and ischemic stroke: a role for nicotine? Trends Pharmacol Sci 23:78\u201382","journal-title":"Trends Pharmacol Sci"},{"key":"9763_CR6","doi-asserted-by":"publisher","first-page":"e36752","DOI":"10.1371\/journal.pone.0036752","volume":"7","author":"YS Ho","year":"2012","unstructured":"Ho YS, Yang X, Yeung SC, Chiu K, Lau CF, Tsang AW, Mak JC, Chang RC (2012) Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats. PLoS One 7:e36752","journal-title":"PLoS One"},{"key":"9763_CR7","doi-asserted-by":"publisher","unstructured":"Hutton SR, Pevny LH (2008) Isolation, culture, and differentiation of progenitor cells from the central nervous system. CSH Protocol 2008:pdb prot5077. doi:10.1101\/pdb.prot5077","DOI":"10.1101\/pdb.prot5077"},{"key":"9763_CR8","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1158\/1940-6207.CAPR-12-0368","volume":"6","author":"AR Iskandar","year":"2013","unstructured":"Iskandar AR, Liu C, Smith DE, Hu KQ, Choi SW, Ausman LM, Wang XD (2013) Beta-cryptoxanthin restores nicotine-reduced lung SIRT1 to normal levels and inhibits nicotine-promoted lung tumorigenesis and emphysema in A\/J mice. Cancer Prev Res (Phila) 6:309\u2013320","journal-title":"Cancer Prev Res (Phila)"},{"key":"9763_CR9","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.neulet.2013.04.027","volume":"545","author":"A Keser","year":"2013","unstructured":"Keser A, Nesil T, Kanit L, Pogun S (2013) Brain nitric oxide metabolites in rats preselected for nicotine preference and intake. Neurosci Lett 545:102\u2013106","journal-title":"Neurosci Lett"},{"key":"9763_CR10","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.reprotox.2012.05.097","volume":"34","author":"C Lin","year":"2012","unstructured":"Lin C, Yon JM, Jung AY, Lee JG, Jung KY, Kang JK, Lee BJ, Yun YW, Nam SY (2012) Resveratrol prevents nicotine-induced teratogenesis in cultured mouse embryos. Reprod Toxicol 34:340\u2013346","journal-title":"Reprod Toxicol"},{"key":"9763_CR11","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1080\/15287394.2012.695985","volume":"75","author":"LH Lobo Torres","year":"2012","unstructured":"Lobo Torres LH, Moreira WL, Tamborelli Garcia RC, Annoni R, Nicoletti Carvalho AL, Teixeira SA, Pacheco-Neto M, Muscara MN, Camarini R, de Melo Loureiro AP, Yonamine M, Mauad T, Marcourakis T (2012) Environmental tobacco smoke induces oxidative stress in distinct brain regions of infant mice. J Toxic Environ Health A 75:971\u2013980","journal-title":"J Toxic Environ Health A"},{"key":"9763_CR12","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1111\/j.1471-4159.2005.03162.x","volume":"94","author":"PR Lockman","year":"2005","unstructured":"Lockman PR, Van der Schyf CJ, Abbruscato TJ, Allen DD (2005) Chronic nicotine exposure alters blood\u2013brain barrier permeability and diminishes brain uptake of methyllycaconitine. J Neurochem 94:37\u201344","journal-title":"J Neurochem"},{"key":"9763_CR13","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1007\/s12031-009-9230-7","volume":"40","author":"D Mao","year":"2010","unstructured":"Mao D, McGehee DS (2010) Nicotine and behavioral sensitization. J Mol Neurosci MN 40:154\u2013163","journal-title":"J Mol Neurosci MN"},{"key":"9763_CR14","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.neuroscience.2006.12.012","volume":"145","author":"G Mudo","year":"2007","unstructured":"Mudo G, Belluardo N, Mauro A, Fuxe K (2007) Acute intermittent nicotine treatment induces fibroblast growth factor-2 in the subventricular zone of the adult rat brain and enhances neuronal precursor cell proliferation. Neuroscience 145:470\u2013483","journal-title":"Neuroscience"},{"key":"9763_CR15","first-page":"631","volume":"16","author":"A Pance","year":"2002","unstructured":"Pance A, Chantome A, Reveneau S, Bentrari F, Jeannin JF (2002) A repressor in the proximal human inducible nitric oxide synthase promoter modulates transcriptional activation. FASEB J Off Publ Fed Am Soc Exp Biol 16:631\u2013633","journal-title":"FASEB J Off Publ Fed Am Soc Exp Biol"},{"key":"9763_CR16","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1007\/s11064-006-9256-y","volume":"32","author":"SY Park","year":"2007","unstructured":"Park SY, Koh YJ, Cho JH, Oh DY, Shin SA, Lee KS, Lee HB, Han JS (2007) Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells. Neurochem Res 32:481\u2013488","journal-title":"Neurochem Res"},{"key":"9763_CR17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s00213-009-1630-4","volume":"207","author":"MM Pascual","year":"2009","unstructured":"Pascual MM, Pastor V, Bernabeu RO (2009) Nicotine-conditioned place preference induced CREB phosphorylation and Fos expression in the adult rat brain. Psychopharmacology 207:57\u201371","journal-title":"Psychopharmacology"},{"key":"9763_CR18","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/j.1471-4159.2010.07149.x","volume":"116","author":"V Pastor","year":"2011","unstructured":"Pastor V, Host L, Zwiller J, Bernabeu R (2011) Histone deacetylase inhibition decreases preference without affecting aversion for nicotine. J Neurochem 116:636\u2013645","journal-title":"J Neurochem"},{"key":"9763_CR19","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1038\/ncb1700","volume":"10","author":"T Prozorovski","year":"2008","unstructured":"Prozorovski T, Schulze-Topphoff U, Glumm R, Baumgart J, Schroter F, Ninnemann O, Siegert E, Bendix I, Brustle O, Nitsch R, Zipp F, Aktas O (2008) Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol 10:385\u2013394","journal-title":"Nat Cell Biol"},{"key":"9763_CR20","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1002\/mds.25028","volume":"27","author":"M Quik","year":"2012","unstructured":"Quik M, Perez XA, Bordia T (2012) Nicotine as a potential neuroprotective agent for Parkinson\u2019s disease. Move Disord Off J Move Disord Soc 27:947\u2013957","journal-title":"Move Disord Off J Move Disord Soc"},{"key":"9763_CR21","first-page":"29","volume":"4","author":"JP Ruiz","year":"2012","unstructured":"Ruiz JP, Pelaez D, Dias J, Ziebarth NM, Cheung HS (2012) The effect of nicotine on the mechanical properties of mesenchymal stem cells. Cell Health Cytoskeleton 4:29\u201335","journal-title":"Cell Health Cytoskeleton"},{"key":"9763_CR22","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1007\/s00702-005-0370-2","volume":"112","author":"AS Shingo","year":"2005","unstructured":"Shingo AS, Kito S (2005) Effects of nicotine on neurogenesis and plasticity of hippocampal neurons. J Neural Transm 112:1475\u20131478","journal-title":"J Neural Transm"},{"key":"9763_CR23","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1634\/stemcells.2006-0131","volume":"25","author":"A Torroglosa","year":"2007","unstructured":"Torroglosa A, Murillo-Carretero M, Romero-Grimaldi C, Matarredona ER, Campos-Caro A, Estrada C (2007) Nitric oxide decreases subventricular zone stem cell proliferation by inhibition of epidermal growth factor receptor and phosphoinositide-3-kinase\/Akt pathway. Stem Cells 25:88\u201397","journal-title":"Stem Cells"},{"key":"9763_CR24","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1002\/jnr.22631","volume":"89","author":"G Turgeman","year":"2011","unstructured":"Turgeman G, Pinkas A, Slotkin TA, Tfilin M, Langford R, Yanai J (2011) Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells. J Neurosci Res 89:1185\u20131193","journal-title":"J Neurosci Res"},{"key":"9763_CR25","doi-asserted-by":"publisher","first-page":"107ps143","DOI":"10.1126\/scitranslmed.3003278","volume":"3","author":"ND Volkow","year":"2011","unstructured":"Volkow ND (2011) Epigenetics of nicotine: another nail in the coughing. Sci Transl Med 3:107ps143","journal-title":"Sci Transl Med"},{"key":"9763_CR26","first-page":"35","volume":"62","author":"J Yu","year":"2010","unstructured":"Yu J, Auwerx J (2010) Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulation. Pharmacol Res Off J Ital Pharmacol Soc 62:35\u201341","journal-title":"Pharmacol Res Off J Ital Pharmacol Soc"}],"container-title":["In Vitro Cellular & Developmental Biology - Animal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11626-014-9763-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11626-014-9763-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11626-014-9763-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11626-014-9763-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:16:53Z","timestamp":1744172213000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11626-014-9763-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,2]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["9763"],"URL":"https:\/\/doi.org\/10.1007\/s11626-014-9763-0","relation":{},"ISSN":["1071-2690","1543-706X"],"issn-type":[{"value":"1071-2690","type":"print"},{"value":"1543-706X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,2]]},"assertion":[{"value":"9 February 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}