{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:15:22Z","timestamp":1780622122036,"version":"3.54.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chin. J. Integr. Med."],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1007\/s11655-010-0782-3","type":"journal-article","created":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T05:36:06Z","timestamp":1309757766000},"page":"499-504","source":"Crossref","is-referenced-by-count":13,"title":["Synergistic effects of tetrandrine on the antifungal activity of topical ketoconazole cream in the treatment of dermatophytoses: A clinical trial"],"prefix":"10.1007","volume":"17","author":[{"given":"Jian-ping","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-dong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge-hua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai-li","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-bao","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,7,3]]},"reference":[{"key":"782_CR1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1439-0507.2008.01606.x","volume":"514","author":"B. Havlickova","year":"2008","unstructured":"Havlickova B, Czaika VA, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses 2008;51(4):2\u201315.","journal-title":"Mycoses"},{"key":"782_CR2","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1128\/CDLI.6.6.921-923.1999","volume":"6","author":"M.A. Ghannoum","year":"1999","unstructured":"Ghannoum MA, Elewski B. Successful treatment of fluconazole-resistant oropharyngeal candidiasis by a combination of fluconazole and terbinafine. Clin Diag Lab Immunol 1999;6:921\u2013923.","journal-title":"Clin Diag Lab Immunol"},{"issue":"Suppl1","key":"782_CR3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ijantimicag.2006.03.016","volume":"27","author":"C. Fohrer","year":"2006","unstructured":"Fohrer C, Fornecker L, Nivoix Y, Cornila C, Marinescu C, Herbrecht R. Antifungal combination treatment: a future perspective. Int J Antimicrob Agents 2006;27(Suppl 1): 25\u201330.","journal-title":"Int J Antimicrob Agents"},{"issue":"14","key":"782_CR4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1439-0507.2008.01615.x","volume":"51","author":"B. Havlickova","year":"2008","unstructured":"Havlickova B, Friedrich M. The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses. Mycoses 2008;51(14):16\u201326.","journal-title":"Mycoses"},{"key":"782_CR5","first-page":"454","volume":"39","author":"F. Li","year":"2006","unstructured":"Li F, Zhang H. In vitro study of the synergistic effect of tetrandrine and fluconazole against Candida albicans. Chin J Dermatol (Chin) 2006;39:454\u2013456.","journal-title":"Chin J Dermatol (Chin)"},{"key":"782_CR6","first-page":"474","volume":"23","author":"K. Wang","year":"2007","unstructured":"Wang K, Zhang H, Jiang H, Shi J, GAO A, He H, et, al. In vivo study on tetrandrine as a synergist to fluconazole in murine model of vaginal candidiasis. Chin J Zoonoses (Chin) 2007;23:474\u2013478.","journal-title":"Chin J Zoonoses (Chin)"},{"key":"782_CR7","first-page":"97","volume":"41","author":"A. Gao","year":"2008","unstructured":"Gao A, Zhang H, Mo H, Jiang H, Wang K, Chao H. Molecular mechanism of the synergy between tetrandrine and fluconazole against Candida albicans. Chin J Dermatol (Chin) 2008;41:97\u2013100.","journal-title":"Chin J Dermatol (Chin)"},{"key":"782_CR8","first-page":"13","volume":"25","author":"F. Li","year":"2009","unstructured":"Li F, Zhang H, Shan K. In vitro study on the synergistic effect and mechanism of tetrandrine to fluconazole against hyphal form of Candida albicans. Chin J Zoonoses (Chin) 2009;25:13\u201316.","journal-title":"Chin J Zoonoses (Chin)"},{"key":"782_CR9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1248\/yakushi.129.623","volume":"129","author":"H. Zhang","year":"2009","unstructured":"Zhang H, Gao A, Li F, Zhang G, Ho HI, Liao W. Mechanism of action of tetrandrine, a natural inhibitor of Candida albicans drug efflux pumps. Yakugaku Zasshi 2009;129:623\u2013630.","journal-title":"Yakugaku Zasshi"},{"key":"782_CR10","first-page":"1121","volume":"25","author":"J. Shi","year":"2009","unstructured":"Shi J, Zhang H, Zhang Z, Gao A, Wang K. Clinical investigation on the synergistic effect of tetrandrine on the antifungal activity of fluconazole for vulvovaginal candidiasis. Chin J Zoonoses (Chin) 2009;25:1121\u20131123.","journal-title":"Chin J Zoonoses (Chin)"},{"key":"782_CR11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1055\/s-0029-1185973","volume":"76","author":"H. Zhang","year":"2010","unstructured":"Zhang H, Wang K, Zhang G, Ho HI, Gao A. Synergistic anti-candidal activity of tetrandrine on ketoconazole: an experimental study. Planta Med 2010;76:53\u201361.","journal-title":"Planta Med"},{"key":"782_CR12","first-page":"222","volume":"26","author":"D. Zhang","year":"2010","unstructured":"Zhang D, Zhang H, Li H, Li S, Shi J. In vivo study on tetrandrine as a synergist to econazole against Trichophyton mentagrophytes. Chin J Zoonoses (Chin) 2010;26:222\u2013225.","journal-title":"Chin J Zoonoses (Chin)"},{"key":"782_CR13","first-page":"207","volume":"24","author":"C. Liu","year":"2010","unstructured":"Liu C, Zhang H, Xiang S, Zhang D, Su Y. Experiment on tetrandrine as a synergist to bifonazole against Trichophyton mentagrophytes in vivo. Chin J Dermatovenereol (Chin) 2010;24:207\u2013210.","journal-title":"Chin J Dermatovenereol (Chin)"},{"key":"782_CR14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3314\/jjmm.50.199","volume":"50","author":"Y. Ogawa","year":"2009","unstructured":"Ogawa Y, Hiruma M. Dermatophytosis: a summary of dermatomycosis as a proposal for future revision of the guidelines. Nippon Ishinkin Gakkai Zasshi 2009;50:199\u2013205.","journal-title":"Nippon Ishinkin Gakkai Zasshi"},{"key":"782_CR15","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3314\/jjmm.50.195","volume":"50","author":"T. Mochizuki","year":"2009","unstructured":"Mochizuki T. Diagnosis of cutaneous fungal infection. Jpn J Med Mycol 2009;50:195\u2013198.","journal-title":"Jpn J Med Mycol"},{"key":"782_CR16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1023\/A:1007029918288","volume":"147","author":"J. Kane","year":"1999","unstructured":"Kane J, Summerbell R, Sigler L, Krajden S, Land G. Laboratory handbook of dermatophytes: a clinical guide and laboratory manual of dermatophytes and other filamentous fungi from skin, hair, and nails. Mycopathologia 1999;147:113\u2013114.","journal-title":"Mycopathologia"},{"key":"782_CR17","unstructured":"CLSI\/Clinical and Laboratory Standards Institute \u2014 Reference method for broth dilution antifungal susceptibility testing of conidium-forming filamentous fungi. Wayne 2002 (Approved Standard M38-A)."},{"key":"782_CR18","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2165\/00128071-200708060-00007","volume":"8","author":"C. Borelli","year":"2007","unstructured":"Borelli C, Kl\u00f6vekorn G, Ernst TM, B\u00f6deker RH, Korting HC, Neumeister C. Comparative study of 2% sertaconazole solution and cream formulations in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosis. Am J Clin Dermatol 2007;8:371\u2013378.","journal-title":"Am J Clin Dermatol"},{"key":"782_CR19","first-page":"154","volume":"69","author":"M. Ramam","year":"2003","unstructured":"Ramam M, Prasad HR, Manchanda Y, Khaitan BK, Banerjee U, Mukhopadhyaya A, et al. Randomised controlled trial of topical butenafine in tinea cruris and tinea corporis. Indian J Dermatol Venereol Leprol 2003;69:154\u2013158.","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"782_CR20","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/09546630500375783","volume":"16","author":"A. Singal","year":"2005","unstructured":"Singal A, Pandhi D, Agrawal S, Das S. Comparative efficacy of topical 1% butenafine and 1% clotrimazole in tinea cruris and tinea corporis: a randomized, double-blind trial. J Dermatol Treat 2005;16:331\u2013335.","journal-title":"J Dermatol Treat"},{"key":"782_CR21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1371\/journal.pmed.0050219","volume":"5","author":"E. Snelders","year":"2008","unstructured":"Snelders E, van der Lee HA, Kuijpers J, Rijs AJ, Varga J, Samson RA, et al. Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. Plos Med 2008;5:219.","journal-title":"Plos Med"},{"key":"782_CR22","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0924-8579(02)00246-7","volume":"20","author":"M.M. Wroblewska","year":"2002","unstructured":"Wroblewska MM, Swoboda-Kopec E, Rokosz A, Krawczyk E, Marchel H, Luczak M. Epidermiology of clinical isolates of Candida albicans and their susceptibility to triazoles. Int J Antimicrob Agents 2002;20:472\u2013475.","journal-title":"Int J Antimicrob Agents"},{"key":"782_CR23","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.diagmicrobio.2006.10.011","volume":"57","author":"D.A. Matta da","year":"2007","unstructured":"da Matta DA, de Almeida LP, Machado AM, Azevedo AC, Kusano EJ, Travassos NF, et al. Antifungal susceptibility of 1 000 Candida bloodstream isolates to 5 antifungal drugs: results of a multicenter study conducted in S\u00e3o Paulo, Brazil, 1995\u20132003. Diagn Microbiol Infect Dis 2007;57:399\u2013404.","journal-title":"Diagn Microbiol Infect Dis"},{"key":"782_CR24","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/j.jpedsurg.2008.09.021","volume":"44","author":"C. Xu","year":"2009","unstructured":"Xu C, Liu W, Chen Z, Wang Y, Xiong Z, Ji Y. Effect of prenatal tetrandrine administration on transforming growth factor-beta1 level in the lung of nitrofen-induced congenital diaphragmatic hernia rat model. J Pediatr Surg 2009;44:1611\u20131620.","journal-title":"J Pediatr Surg"},{"key":"782_CR25","first-page":"277","volume":"3","author":"B. Chen","year":"2008","unstructured":"Chen B, Sun Q, Wang X, Gao F, Dai Y, Yin Y, et al. Reversal in multidrug resistance by magnetic nanoparticle of Fe3O4 loaded with adriamycin and tetrandrine in K562\/A02 leukemic cells. Int J Nanomed 2008;3:277\u2013286.","journal-title":"Int J Nanomed"}],"container-title":["Chinese Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-010-0782-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11655-010-0782-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-010-0782-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,21]],"date-time":"2020-06-21T02:20:56Z","timestamp":1592706056000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11655-010-0782-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["782"],"URL":"https:\/\/doi.org\/10.1007\/s11655-010-0782-3","relation":{},"ISSN":["1672-0415","1993-0402"],"issn-type":[{"value":"1672-0415","type":"print"},{"value":"1993-0402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}