{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:15:34Z","timestamp":1761988534348},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T00:00:00Z","timestamp":1350864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chin. J. Integr. Med."],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1007\/s11655-012-1176-x","type":"journal-article","created":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T01:13:05Z","timestamp":1350868385000},"page":"667-674","source":"Crossref","is-referenced-by-count":9,"title":["NADPH oxidase-dependent formation of reactive oxygen species contributes to transforming growth factor \u03b21-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells, and the role of astragalus intervention"],"prefix":"10.1007","volume":"20","author":[{"given":"Xiao-xian","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-juan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-lin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-juan","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-ning","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,10,22]]},"reference":[{"key":"1176_CR1","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1093\/ndt\/14.5.1208","volume":"14","author":"D.I. Leavesley","year":"1999","unstructured":"Leavesley DI, Stanley JM, Faull RJ. Epidermal growth factor modifies the expression and function of extracellular matrix adhesion receptors expressed by peritoneal mesothelial cells from patients on CAPD. Nephrol Dial Transplant 1999;14:1208\u20131216.","journal-title":"Nephrol Dial Transplant"},{"key":"1176_CR2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/089686089101100106","volume":"11","author":"M.G. Betjes","year":"1991","unstructured":"Betjes MG, Bos HJ, Krediet RT, Arisz L. The mesothelial cells in CAPD effluent and their relation to peritonitis incidence. Perit Dial Int 1991;11:22\u201326.","journal-title":"Perit Dial Int"},{"key":"1176_CR3","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1164\/rccm.200501-017PP","volume":"172","author":"V.L. Kinnula","year":"2005","unstructured":"Kinnula VL, Fattman CL, Tan RJ, Oury TD. Oxidative stress in pulmonary fibrosis. A possible role for redox modulatory therapy. Am J Respir Crit Care Med 2005;172:417\u2013422.","journal-title":"Am J Respir Crit Care Med"},{"key":"1176_CR4","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/ki.2010.516","volume":"79","author":"J.L. Barnes","year":"2011","unstructured":"Barnes JL, Gorin Y. Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int 2011;79:944\u2013956.","journal-title":"Kidney Int"},{"key":"1176_CR5","first-page":"81","volume":"24","author":"J.Y. Xu","year":"2006","unstructured":"Xu JY, Wang JX, Meng XQ. Effect of Astragalus Injection on dialysis efficiency and peritoneal ultrastructure in rats. J Henan Univ Sci Tech (Med Sci, Chin) 2006; 24:81\u201383.","journal-title":"J Henan Univ Sci Tech (Med Sci, Chin)"},{"key":"1176_CR6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.lab.2003.09.005","volume":"143","author":"L. Gotloib","year":"2004","unstructured":"Gotloib L, Wajsbrot V, Cuperman Y, Shostak A. Acute oxidative stress induces peritoneal hyperpermeability, mesothelial loss, and fibrosis. J Lab Clin Med 2004;143:31\u201340.","journal-title":"J Lab Clin Med"},{"key":"1176_CR7","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1177\/089686080102100612","volume":"21","author":"T. Linden","year":"2001","unstructured":"Linden T, Musi B, Jarkelid L, Forsback G, Kjellstrand P, Deppisch R, et al. Glucose degradation products in peritoneal dialysis fluids may have both local and systemic effects: a study of residual fluid and mesothelial cells. Perit Dial Int 2001;21:607\u2013610.","journal-title":"Perit Dial Int"},{"key":"1176_CR8","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1681\/ASN.V12112434","volume":"12","author":"J. Witowski","year":"2001","unstructured":"Witowski J, Wisniewska J, Korybalska K, Bender TO, Breborowicz A, Gahl GM, et al. Prolonged exposure to glucose degradation products impairs viability and function of human peritoneal mesothelial cells. J Am Soc Nephrol 2001;12:2434\u20132441.","journal-title":"J Am Soc Nephrol"},{"key":"1176_CR9","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJMoa020809","volume":"348","author":"Y\u00e1\u00f1ez-M\u00f3","year":"2003","unstructured":"Y\u00e1\u00f1ez-M\u00f3, Lara-Pezzi E, Selgas R, Selgas R, Ram\u00edrez-Huesca M, Dom\u00ednguez-Jim\u00e9nez C, et al. Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med 2003;348:403\u2013413.","journal-title":"N Engl J Med"},{"key":"1176_CR10","first-page":"612","volume":"22","author":"X.R. Dou","year":"2006","unstructured":"Dou XR, Yu WQ, Hao WK, Nie J, Li XY, Chen WF, et al. Smad7 overexpression inhibits epithelial-mesenchymal transition in peritoneal fibrosis rat model. Chin J Nephrol (Chin) 2006;22:612\u2013616.","journal-title":"Chin J Nephrol (Chin)"},{"key":"1176_CR11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.taap.2010.11.016","volume":"251","author":"S. Ghatak","year":"2011","unstructured":"Ghatak S, Biswas A, Dhali GK, Chowdhury A, Boyer JL, Santra A. Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice. Toxicol Appl Pharmacol 2011;251:59\u201369.","journal-title":"Toxicol Appl Pharmacol"},{"key":"1176_CR12","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.biocel.2011.04.003","volume":"43","author":"B. Crestani","year":"2011","unstructured":"Crestani B, Besnard V, Boczkowski J. Signalling pathways from NADPH oxidase-4 to idiopathic pulmonary fibrosis. Int J Biochem Cell Biol 2011;43:1086\u20131089.","journal-title":"Int J Biochem Cell Biol"},{"issue":"11","key":"1176_CR13","doi-asserted-by":"crossref","first-page":"e14003","DOI":"10.1371\/journal.pone.0014003","volume":"5","author":"M. Bocchinol","year":"2010","unstructured":"Bocchinol M, Agnese S, Fagone E, Svegliati S, Grieco D, Vancheri C, et al. Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis. PLoS One 2010;5(11):e14003.","journal-title":"PLoS One"},{"key":"1176_CR14","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1164\/rccm.200602-205OC","volume":"174","author":"C.D. Cool","year":"2006","unstructured":"Cool CD, Groshong SD, Rai PR, Henson PM, Stewart JS, Brown KK. Fibroblast foci are not discrete sites of lung injury or repair: the fibroblast reticulum. Am J Respir Crit Care Med 2006;174:654\u2013658.","journal-title":"Am J Respir Crit Care Med"},{"key":"1176_CR15","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1681\/ASN.2004050425","volume":"16","author":"D.Y. Rhyu","year":"2005","unstructured":"Rhyu DY, Yang Y, Ha H, Lee GT, Song JS, Lee HB, et al. Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelialmesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 2005;16:667\u2013675.","journal-title":"J Am Soc Nephrol"},{"key":"1176_CR16","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/ki.2010.516","volume":"79","author":"J.L. Barnes","year":"2011","unstructured":"Barnes JL, Gorin Y. Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int 2011;79:944\u2013956.","journal-title":"Kidney Int"},{"key":"1176_CR17","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1074\/jbc.M007597200","volume":"276","author":"A. Shiose","year":"2001","unstructured":"Shiose A, Kuroda J, Tsuruya K, Hirai M, Hirakata H, Naito S, et al. A novel superoxide-producing NAD(P)H oxidase in kidney. J Biol Chem 2001;276:1417\u20131423.","journal-title":"J Biol Chem"},{"key":"1176_CR18","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1006\/abbi.2001.2642","volume":"397","author":"B.M. Babior","year":"2002","unstructured":"Babior BM, Lambeth JD, Nauseef W. The neutrophil NAD(P) H oxidase. Arch Biochem Biophys 2002;397:342\u2013344.","journal-title":"Arch Biochem Biophys"},{"key":"1176_CR19","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1161\/01.RES.86.5.494","volume":"86","author":"K.K. Griendling","year":"2000","unstructured":"Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000;86:494\u2013501.","journal-title":"Circ Res"},{"key":"1176_CR20","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1681\/ASN.V571483","volume":"5","author":"S.A. Jones","year":"1995","unstructured":"Jones SA, Hancock JT, Jones OT, Neubauer A, Topley N. The expression of NAD(P)H oxidase components in human glomerular mesangial cells: detection of protein and mRNA for p47phox, p67phox, and p22phox. J Am Soc Nephrol 1995;5:1483\u20131491.","journal-title":"J Am Soc Nephrol"},{"key":"1176_CR21","doi-asserted-by":"crossref","first-page":"5452","DOI":"10.1074\/jbc.M001004200","volume":"276","author":"S. Yang","year":"2001","unstructured":"Yang S, Madyastha P, Bingel S, Ries W, Key L. A new superoxide-generating oxidase in murine osteoclasts. J Biol Chem 2001;276:5452\u20135458.","journal-title":"J Biol Chem"},{"key":"1176_CR22","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jep.2008.04.012","volume":"118","author":"Y. Yang","year":"2008","unstructured":"Yang Y, Yang S, Chen M, Zhang XX, Zou Y, Zhang X. Compound Astragalus and Salvia miltiorrhiza extract exerts anti-fibrosis by mediating TGF-beta\/Smad signaling in myofibroblasts. J Ethnopharmacol 2008;118:264\u2013270.","journal-title":"J Ethnopharmacol"},{"key":"1176_CR23","first-page":"575","volume":"13","author":"X. Zhou","year":"2005","unstructured":"Zhou X, Dai LL, Jia LP, Zheng YY, Wang WB. Study on the inhibitive effect of Astragalus Injection solution on hepatic fibrosis in rats. Chin Hepatol J (Chin) 2005;13:575\u2013578.","journal-title":"Chin Hepatol J (Chin)"},{"key":"1176_CR24","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.jep.2007.04.005","volume":"112","author":"W.Y. Sun","year":"2007","unstructured":"Sun WY, Wei W, Wu L, Gui SY, Wang H. Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in rats. J Ethnopharmacol 2007;112:514\u2013523.","journal-title":"J Ethnopharmacol"},{"key":"1176_CR25","first-page":"917","volume":"18","author":"L. Guo","year":"2011","unstructured":"Guo L, Bai SP, Zhao L, Wang XH. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival. Med Oncol 2011;18:917\u2013923.","journal-title":"Med Oncol"},{"key":"1176_CR26","first-page":"918","volume":"29","author":"L.M. Yao","year":"2009","unstructured":"Yao LM, Liu TW, Wu WF. Effects of Astragalus Injection in reversing left ventricular hypertrophy induced by renal hypertension in rats. Chin J Integr Tradit West Med (Chin) 2009;29:918\u2013921.","journal-title":"Chin J Integr Tradit West Med (Chin)"}],"container-title":["Chinese Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-012-1176-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11655-012-1176-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-012-1176-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T11:51:31Z","timestamp":1643543491000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11655-012-1176-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,22]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["1176"],"URL":"https:\/\/doi.org\/10.1007\/s11655-012-1176-x","relation":{},"ISSN":["1672-0415","1993-0402"],"issn-type":[{"value":"1672-0415","type":"print"},{"value":"1993-0402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,22]]}}}