{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:47:21Z","timestamp":1787726841435,"version":"build-2784847793"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chin. J. Integr. Med."],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1007\/s11655-013-1653-x","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T01:16:37Z","timestamp":1386119797000},"page":"913-917","source":"Crossref","is-referenced-by-count":12,"title":["The effect of Chaiqin Chengqi Decoction (\u67f4\u82a9\u627f\u6c14\u6c64) on modulating serum matrix metalloproteinase 9 in patients with severe acute pancreatitis"],"prefix":"10.1007","volume":"19","author":[{"given":"Jia","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-nan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-qi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-bao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,12,5]]},"reference":[{"key":"1653_CR1","doi-asserted-by":"crossref","first-page":"R123","DOI":"10.1186\/cc7978","volume":"13","author":"YS Peng","year":"2009","unstructured":"Peng YS, Wu CS, Chen YC, Lien JM, Tian YC, Fang JT, et al. Critical illness-related corticosteroid insufficiency in patients with severe acute biliary pancreatitis: a prospective cohort study. Crit Care 2009;13:R123.","journal-title":"Crit Care"},{"key":"1653_CR2","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.3748\/wjg.15.2945","volume":"15","author":"AF Tonsi","year":"2009","unstructured":"Tonsi AF, Bacchion M, Crippa S, Malleo G, Bassi C. Acute pancreatitis at the beginning of the 21st century: the state of the art. World J Gastroenterol 2009;15:2945\u20132959.","journal-title":"World J Gastroenterol"},{"key":"1653_CR3","first-page":"524","volume":"56","author":"T Ishikawa","year":"2009","unstructured":"Ishikawa T, Imai M, Kamimura H, Ushiki T, Tsuchiya A, Togashi T, et al. Therapeutic efficacy of continuous arterial infusion of the protease inhibitor and the antibiotics and via celiac and superior mesenteric artery for severe acute pancreatitis-pilot study. Hepatogastroenterology 2009;56:524\u2013528.","journal-title":"Hepatogastroenterology"},{"key":"1653_CR4","first-page":"RA147","volume":"15","author":"RK Jha","year":"2009","unstructured":"Jha RK, Ma Q, Sha H, Palikhe M. Acute pancreatitis: a literature review. Med Sci Monit 2009;15:RA147\u2013RA156.","journal-title":"Med Sci Monit"},{"key":"1653_CR5","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1477-2574.2009.00038.x","volume":"11","author":"DJ Mole","year":"2009","unstructured":"Mole DJ, Olabi B, Robinson V, Garden OJ, Parks RW. Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records. HPB (Oxford) 2009;11:166\u2013170.","journal-title":"HPB (Oxford)"},{"key":"1653_CR6","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1097\/01.mcg.0000177257.87939.00","volume":"39","author":"CS Pitchumoni","year":"2005","unstructured":"Pitchumoni CS, Patel NM, Shah P. Factors influencing mortality in acute pancreatitis: can we alter them? J Clin Gastroenterol 2005;39:798\u2013814.","journal-title":"J Clin Gastroenterol"},{"key":"1653_CR7","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1556\/OH.2008.28482","volume":"2008;149","author":"K Darvas","year":"2008","unstructured":"Darvas K, Fut\u00f3 J, Okr\u00f6s I, Gondos T, Csom\u00f3s A, Kupcsulik P. Principles of intensive care in severe acute pancreatitis in 2008. Orv Hetil 2008;149:2211\u20132220","journal-title":"Orv Hetil"},{"key":"1653_CR8","first-page":"190","volume":"5","author":"X Liu","year":"2002","unstructured":"Liu X, Liu Q, Pan C. Early preventive treatment for severe acute pancreatitis combined with lung injury. Chin J Traumatol 2002;5:190\u2013192.","journal-title":"Chin J Traumatol"},{"key":"1653_CR9","first-page":"443","volume":"75","author":"M Roseano","year":"2004","unstructured":"Roseano M, Lovadina S, Calligarisl, Ursic I, Cuviello A, Liguori G. The multidisciplinary management of acute pancreatitis: a review of 244 cases. Ann Ital Chir 2004;75:443\u2013453.","journal-title":"Ann Ital Chir"},{"key":"1653_CR10","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.jtcvs.2008.11.004","volume":"137","author":"A Sokal","year":"2009","unstructured":"Sokal A, Zembala M, Radomski A, Kocher A, Pacholewicz J, Los J, et al. A differential release of matrix metalloproteinases 9 and 2 during coronary artery bypass grafting and off-pump coronary artery bypass surgery. J Thorac Cardiovasc Surg 2009;137:1218\u20131224.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1653_CR11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jss.2004.08.025","volume":"123","author":"H Chen","year":"2005","unstructured":"Chen H, Inocencio R, Alam HB, Rhee P, Koustova E. Differential expression of extracellular matrix remodeling genes in rat model of hemorrhagic shock and resuscitation. Surg Res 2005;123:235\u2013244.","journal-title":"Surg Res"},{"key":"1653_CR12","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0167-4838(99)00279-4","volume":"1477","author":"K Brew","year":"2000","unstructured":"Brew K, Dinakarpandian D, Nagase H. Tissue Inhibitors of metalloptoteinases: evolution, structure and function. Biochim Biophys Acta 2000;1477:267\u2013283.","journal-title":"Biochim Biophys Acta"},{"key":"1653_CR13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s001340050009","volume":"26","author":"S Gando","year":"2000","unstructured":"Gando S, Nanzaki S, Morimoto Y, Kobayashi S, Kemmotsu O. Out-of-hospital cardiac arrest increases soluble vascular endothelial adhesion molecules and neutrophil elastase associated with endothelial injury. Intensive Care Med 2000;26:38\u201344.","journal-title":"Intensive Care Med"},{"key":"1653_CR14","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/CCM.0b013e318192fe4f","volume":"37","author":"N Sennoun","year":"2009","unstructured":"Sennoun N, Meziani F, Dessebe O, Cattan V, Collin S, Montemont C, et al. Activated protein C improves lipopolysaccharide-induced cardiovascular dysfunction by decreasing tissular inflammation and oxidative stress. Crit Care Med 2009;37:246\u2013255.","journal-title":"Crit Care Med"},{"key":"1653_CR15","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-3083.2008.02122.x","volume":"68","author":"A Castellheim","year":"2008","unstructured":"Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, et al. New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs. Scand J Immunol 2008;68:75\u201384.","journal-title":"Scand J Immunol"},{"key":"1653_CR16","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.surg.2008.08.036","volume":"145","author":"Y Mikami","year":"2009","unstructured":"Mikami Y, Dobsch\u00fctz EV, Sommer O, Wellner U, Unno M, Hopt U, et al. Matrix metalloproteinase-9 derived from polymorphonuclear neutrophils increases gut barrier dysfunction and bacterial translocation in rat severe acute pancreatitis. Surgery 2009;145:147\u201356.","journal-title":"Surgery"},{"key":"1653_CR17","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1159\/000212080","volume":"80","author":"M Sochor","year":"2009","unstructured":"Sochor M, Richter S, Schmidt A, Hempel S, Hopt UT, Keck T. Inhibition of matrix metalloproteinase-9 with doxycycline reduces pancreatitis-associated lung injury. Digestion 2009;80:65\u201373.","journal-title":"Digestion"},{"key":"1653_CR18","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1620\/tjem.208.261","volume":"208","author":"P Chen","year":"2006","unstructured":"Chen P, Yuan Y, Wang S, Zhan L, Xu J. Serum matrix metalloproteinase 9 as a marker for the assessment of severe acute pancreatitis. Tohoku J Exp Med 2006;208:261\u2013266.","journal-title":"Tohoku J Exp Med"},{"key":"1653_CR19","first-page":"322","volume":"29","author":"ZC Wang","year":"2009","unstructured":"Wang ZC, Xue P, Huang ZW. Effect of an early application of Chaiqin Chengqi Decoction in treating severe acute pancreatitis complicated with acute respiratory distrees syndrome. Chin J Integr Tradit West Med (Chin) 2009;29:322\u2013324.","journal-title":"Chin J Integr Tradit West Med (Chin)"},{"key":"1653_CR20","first-page":"204","volume":"35","author":"XB Liu","year":"2004","unstructured":"Liu XB, Jiang JM, Huang ZW, Tian BL, Hu WM, Xia Q, et al. Clinical study on the treatment of severe acute pancreatitis by integrated traditional Chinese medicine and Western medicine. J Sichuan Univ (Med Sci ed) 2004;35:204\u2013208.","journal-title":"J Sichuan Univ (Med Sci ed)"},{"key":"1653_CR21","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3736\/jcim20080215","volume":"6","author":"YH Li","year":"2008","unstructured":"Li YH, Huang ZW, Xue P, Guo J, He FQ, You Z, et al. Effects of Chaiqin Chengqi Decoction on activation of nuclear factor-kappaB in pancreas of rats with acute necrotizing pancreatitis. J Chin Integr Med (Chin) 2008;6:180\u2013184.","journal-title":"J Chin Integr Med (Chin)"},{"key":"1653_CR22","first-page":"66","volume":"37","author":"P Xue","year":"2006","unstructured":"Xue P, Huang ZW, Zhang HY, Xia Q, Li YH, Wang ZC, et al. Impact of Chaiqin Chengqi Decoction on cholinergic antiinflammatory pathway in rats with severe acute pancreatitis. J Sichuan Univ (Med Sci ed) 2006;37:66\u201368.","journal-title":"J Sichuan Univ (Med Sci ed)"},{"key":"1653_CR23","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.3748\/wjg.14.2343","volume":"14","author":"P Xue","year":"2008","unstructured":"Xue P, Deng LH, Zhang ZD, Yang XN, Xia Q, Xiang DK, et al. Effect of Chaiqin chengqi Decoction on sarco\/endoplasmic reticulum Ca2+-ATPase mRNA expression of pancreatic tissues in acute pancreatitis rats. World J Gastroenterol 2008;14:2343\u20132348.","journal-title":"World J Gastroenterol"},{"key":"1653_CR24","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1046\/j.1440-1746.17.s1.2.x","volume":"17","author":"J Toouli","year":"2002","unstructured":"Toouli J, Brooke-Smith M, Bassi C, Carr-Locke D, Telford J, Freeny P, et al. Guidelines for the management of acute pancreatitis. J Gastroenter Hepat 2002;17:S15\u2013S39.","journal-title":"J Gastroenter Hepat"},{"key":"1653_CR25","doi-asserted-by":"crossref","first-page":"474","DOI":"10.3748\/wjg.14.474","volume":"14","author":"P Xue","year":"2008","unstructured":"Xue P, Deng LH, Xia Q, Zhang ZD, Hu WM, Yang XN, et al. Impact of alanyl-glutamine dipeptide on severe acute pancreatitis in early stage. World J Gastroenterol 2008;14:474\u2013478.","journal-title":"World J Gastroenterol"},{"key":"1653_CR26","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1440-1746.2008.05758.x","volume":"24","author":"P Xue","year":"2009","unstructured":"Xue P, Deng LH, Zhang ZD, Yang XN, Wan MH, Song B, et al. Effect of antibiotic prophylaxis on acute necrotizing pancreatitis: results of a randomized controlled trial. J Gastroenterol Hepatol 2009;24:736\u2013742.","journal-title":"J Gastroenterol Hepatol"},{"key":"1653_CR27","first-page":"773","volume":"35","author":"Pancreatic Surgery Association of Chinese Medical Association.","year":"1997","unstructured":"Pancreatic Surgery Association of Chinese Medical Association. The criteria of clinical diagnosis and classification system for acute pancreatitis (the second project, 1996). Chin J Surg 1997;35:773\u2013775.","journal-title":"Chin J Surg"},{"key":"1653_CR28","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.1007\/s10620-008-0668-1","volume":"54","author":"P Xue","year":"2009","unstructured":"Xue P, Deng LH, Zhang ZD, Yang XN, Wan MH, Song B, et al. Infectious complications in patients with severe acute pancreatitis. Dig Dis Sci 2009;54:2748\u20132753.","journal-title":"Dig Dis Sci"},{"key":"1653_CR29","doi-asserted-by":"crossref","first-page":"166","DOI":"10.2298\/SARH0904166G","volume":"137","author":"T Glisi\u0107","year":"2009","unstructured":"Glisi\u0107 T, Sijacki A, Vukovi\u0107 V, Suboti\u0107 A. Bernard organ failure score in estimation of most severe forms of acute pancreatitis. Srp Arh Celok Lek 2009;137:166\u2013170.","journal-title":"Srp Arh Celok Lek"},{"key":"1653_CR30","first-page":"271","volume":"10","author":"JD Wig","year":"2009","unstructured":"Wig JD, Bharathy KG, Kochhar R, Yadav TD, Kudari AK, Doley RP, et al. Correlates of organ failure in severe acute pancreatitis. JOP 2009;10:271\u2013275.","journal-title":"JOP"}],"container-title":["Chinese Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-013-1653-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11655-013-1653-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-013-1653-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T15:00:43Z","timestamp":1559401243000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11655-013-1653-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["1653"],"URL":"https:\/\/doi.org\/10.1007\/s11655-013-1653-x","relation":{},"ISSN":["1672-0415","1993-0402"],"issn-type":[{"value":"1672-0415","type":"print"},{"value":"1993-0402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}