{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T23:23:52Z","timestamp":1794525832964,"version":"4.9.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T00:00:00Z","timestamp":1610150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T00:00:00Z","timestamp":1610150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chin. J. Integr. Med."],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1007\/s11655-020-3484-x","type":"journal-article","created":{"date-parts":[[2021,1,10]],"date-time":"2021-01-10T15:03:34Z","timestamp":1610291014000},"page":"195-201","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effects of Bushen Yiqi Huoxue Decoction in Treatment of Patients with Diminished Ovarian Reserve: A Randomized Controlled Trial"],"prefix":"10.1007","volume":"28","author":[{"given":"Jing","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-yao","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-kun","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,9]]},"reference":[{"key":"3484_CR1","doi-asserted-by":"publisher","first-page":"800","DOI":"10.3389\/fendo.2019.00800","volume":"10","author":"SN Chen","year":"2019","unstructured":"Chen SN, Tsui KH, Wang PH, Chern CU, Wen ZH, Lin LT. Dehydroepiandrosterone supplementation improves the outcomes of in vitro fertilization cycles in older patients with diminished ovarian reserve. Front Endocrinol 2019;10:800.","journal-title":"Front Endocrinol"},{"key":"3484_CR2","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1080\/09513590.2019.1640203","volume":"36","author":"S Dragojevic Dikic","year":"2020","unstructured":"Dragojevic Dikic S, Vasiljevic M, Jovanovic A, Dikic S, Jurisic A, Srbinovic L, et al. Premature ovarian insufficiency\u2014novel hormonal approaches in optimizing fertility. Gynecol Endocrinol 2020;36:162\u2013165.","journal-title":"Gynecol Endocrinol"},{"key":"3484_CR3","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/ijc.32706","volume":"147","author":"J Simin","year":"2020","unstructured":"Simin J, Tamimi RM, Callens S, Engstrand L, Brusselaers N. Menopausal hormone therapy treatment options and ovarian cancer risk: a Swedish prospective population-based matched-cohort study. Int J Cancer 2020;147:33\u201344.","journal-title":"Int J Cancer"},{"key":"3484_CR4","doi-asserted-by":"publisher","first-page":"108507","DOI":"10.1016\/j.steroids.2019.108507","volume":"153","author":"P Sahu","year":"2020","unstructured":"Sahu P, Gidwani B, Dhongade HJ. Pharmacological activities of dehydroepiandrosterone: A review. Steroids 2020;153:108507.","journal-title":"Steroids"},{"key":"3484_CR5","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1007\/s10815-018-1152-2","volume":"35","author":"QHY Wong","year":"2018","unstructured":"Wong QHY, Yeung TWY, Yung SSF, Ko JKY, Li HWR, Ng EHY. The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency. J Assist Reprod Genet 2018;35:857\u2013862.","journal-title":"J Assist Reprod Genet"},{"key":"3484_CR6","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1089\/acu.2012.0912","volume":"24","author":"L Hullender Rubin","year":"2012","unstructured":"Hullender Rubin L, Marx BL. Diminished ovarian reserve, clomid, and traditional Chinese medicine: a case study. Med Acupunct 2012;24:273\u2013280.","journal-title":"Med Acupunct"},{"key":"3484_CR7","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s13063-018-2511-0","volume":"19","author":"S Ma","year":"2018","unstructured":"Ma S, Ma R, Xia T, Afnan M, Song X, Xu F, et al. Efficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization\/intracytoplasmic sperm injection: study protocol for a randomized controlled trial. Trials 2018;19:124.","journal-title":"Trials"},{"key":"3484_CR8","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s11655-018-3029-8","volume":"25","author":"JH Zhang","year":"2019","unstructured":"Zhang JH, Wu MS, Wang YF, Jia YM, Li E. Medicine in future and advantages of integrated Chinese and Western medicine. Chin J Integr Med 2019;25:87\u201390.","journal-title":"Chin J Integr Med"},{"key":"3484_CR9","first-page":"211","volume":"26","author":"DT Wen","year":"2015","unstructured":"Wen DT, Li XM, Zhang Q, Liu ZQ, Zhou HP, Wang XY, et al. Professor LI Li-yun\u2019s traditional Chinese medicine clinical thinking on treating infertility with decreased ovarian reserve. Lishizhen Med Mater Med Res (Chin) 2015;26:211\u2013213.","journal-title":"Lishizhen Med Mater Med Res (Chin)"},{"key":"3484_CR10","first-page":"98","volume-title":"Practical dynecology endocrinology","year":"2004","unstructured":"Yu CX, Li CH, eds. Practical dynecology endocrinology. 2nd ed. Shanghai: Fudan University Press; 2004:98.","edition":"2nd ed."},{"key":"3484_CR11","unstructured":"Yue J, ed. Gynecology dndocrinology. 7th ed. Beijing: People\u2019s Medical Publishing House; 2008:310\u2013312."},{"key":"3484_CR12","first-page":"3911","volume":"40","author":"K Ma","year":"2015","unstructured":"Ma K, Liu YF, He JQ, Li M, Shan J. A multi-center, randomized, double-blind clinical study on Bushen Huoxue in treatment of ovulatory dysfunction caused infertility. China J Chin Mater Med (Chin) 2015;40:3911\u20133915.","journal-title":"China J Chin Mater Med (Chin)"},{"key":"3484_CR13","first-page":"1170","volume":"35","author":"Z Zhang","year":"2015","unstructured":"Zhang Z, Zhang XH, He TY. Smoothing Gan reinforcing Shen method adjuvantly treated poor response of diminished ovarian reserve patients in in vitro fertilization and embryo transfer: a clinical study. Chin J Integr Tradit West Med (Chin) 2015;35:1170\u20131174.","journal-title":"Chin J Integr Tradit West Med (Chin)"},{"key":"3484_CR14","doi-asserted-by":"publisher","first-page":"384","DOI":"10.3109\/09513590.2014.1003294","volume":"31","author":"AM Paoletti","year":"2015","unstructured":"Paoletti AM, Cagnacci A, Di Carlo C, Orru MM, Neri M, D\u2019Alterio MN, et al. Clinical effect of hormonal replacement therapy with estradiol associated with noretisterone or drospirenone: a prospective randomized placebo controlled study. Gynecol Endocrinol 2015;31:384\u2013387.","journal-title":"Gynecol Endocrinol"},{"key":"3484_CR15","first-page":"920","volume":"25","author":"L Zhu","year":"2005","unstructured":"Zhu L, Luo SP, Xu LM. Protective effect of Zuogui Pill on ovarian autoimmune injury. Chin J Integr Tradit West Med (Chin) 2005;25:920\u2013924.","journal-title":"Chin J Integr Tradit West Med (Chin)"},{"key":"3484_CR16","first-page":"909","volume":"43","author":"EX Jiang","year":"2018","unstructured":"Jiang EX. The regulation of Zuogui Pill on serum sex hormones, IL-6 and IL-7 of mice with immune premature ovarian failure. J Guizhou Med Univ (Chin) 2018;43:909\u2013912.","journal-title":"J Guizhou Med Univ (Chin)"},{"key":"3484_CR17","first-page":"412","volume":"33","author":"Y Liang","year":"2018","unstructured":"Liang Y. Clinical study of modified Zuogui Wan combined with dydrogesterone therapy in the treatment of premature ovarian failure. Guangming J Chin Med (Chin) 2018;33:412\u2013414.","journal-title":"Guangming J Chin Med (Chin)"},{"key":"3484_CR18","doi-asserted-by":"crossref","unstructured":"Practice Committee of the American Society for Reproductive Medicine. Testing and interpreting measures of ovarian reserve: a committee opinion. Fertil Steril 2015;103:e9\u2013e17.","DOI":"10.1016\/j.fertnstert.2014.12.093"},{"key":"3484_CR19","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.ajog.2017.02.027","volume":"217","author":"R Tal","year":"2017","unstructured":"Tal R, Seifer DB. Ovarian reserve testing: a user\u2019s guide. Am J Obstet Gynecol 2017;217:129\u2013140.","journal-title":"Am J Obstet Gynecol"},{"key":"3484_CR20","first-page":"158","volume":"13","author":"YY Wei","year":"2011","unstructured":"Wei YY, Zhang ZJ, Ying XU, Zhang JJ, Chen J, Wang ZT. Estrogenic effect of Psoraleae Fructus in ovariectomized rats. Chin J Exp Med Formul (Chin) 2011;13:158\u2013161.","journal-title":"Chin J Exp Med Formul (Chin)"},{"key":"3484_CR21","first-page":"126","volume":"21","author":"LR Cai","year":"2001","unstructured":"Cai LR, Li DJ, Sun XX. Experimental study on preventive and therapeutic effect of Bushen Huoxue Recipe on autoimmune premature ovarian failure model. Chin J Integr Tradit West Med (Chin) 2001;21:126\u2013129.","journal-title":"Chin J Integr Tradit West Med (Chin)"},{"key":"3484_CR22","doi-asserted-by":"publisher","first-page":"e7","DOI":"10.1016\/j.fertnstert.2007.01.043","volume":"88","author":"AY Wong","year":"2007","unstructured":"Wong AY, Chan KS, Lau WL, Tang LC. Pregnancy outcome of a patient with atypical polypoid adenomyoma. Fertil Steril 2007;88:e7\u2013e9.","journal-title":"Fertil Steril"},{"key":"3484_CR23","first-page":"94","volume":"229","author":"JJ Ren","year":"2016","unstructured":"Ren JJ, Zhu L, Wang SL, Gao J, Luo SP, Xu LM. Effect of anti-mullerian hormone in immune premature ovarian failure and mechanism of Zuogui Wan. Chin J Exp Med Formul (Chin) 2016;229:94\u201399.","journal-title":"Chin J Exp Med Formul (Chin)"},{"key":"3484_CR24","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.3736\/jcim20101106","volume":"5","author":"HP Liu","year":"2010","unstructured":"Liu HP, You ZL, Lei L, WU JJ, Zhang GM, Zhu W, et al. Effect of Bushen Huoxue Prescription on Bcl-2\/Bax protein of apoptosis contress genes in follicle of immune premature ovarian failure mice. Chin Arch Tradit Chin Med (Chin) 2010;5:1036\u20131038.","journal-title":"Chin Arch Tradit Chin Med (Chin)"},{"key":"3484_CR25","first-page":"64","volume":"35","author":"C Gao","year":"2013","unstructured":"Gao C, Liu L, Hu AJ, Feng YT. Research progress in pharmacological study on Chinese materia medica with function of activating blood and resolving stasis. Drug Eval Res (Chin) 2013;35:64\u201368.","journal-title":"Drug Eval Res (Chin)"},{"key":"3484_CR26","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1248\/yakushi.129.855","volume":"129","author":"L Zhang","year":"2009","unstructured":"Zhang L, Du JR, Wang J, Yu DK, Chen YS, He Y, et al. Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats. J Pharm Soc Jap 2009;129:855\u2013859.","journal-title":"J Pharm Soc Jap"}],"container-title":["Chinese Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-020-3484-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11655-020-3484-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-020-3484-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T16:52:26Z","timestamp":1646153546000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11655-020-3484-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,9]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["3484"],"URL":"https:\/\/doi.org\/10.1007\/s11655-020-3484-x","relation":{},"ISSN":["1672-0415","1993-0402"],"issn-type":[{"value":"1672-0415","type":"print"},{"value":"1993-0402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,9]]},"assertion":[{"value":"23 March 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"There is no conflict to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}