{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:07:06Z","timestamp":1788390426182,"version":"build-2803163510"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Chin. J. Integr. Med."],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1007\/s11655-022-3577-9","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T14:03:24Z","timestamp":1655733804000},"page":"872-878","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Ruyi Zhenbao Pills for Patients with Motor and Sensory Dysfunction after Stroke: A Double-Blinded, Randomized Placebo-Controlled Clinical Trial"],"prefix":"10.1007","volume":"28","author":[{"given":"Shan-shan","family":"Ling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-huan","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le-chang","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-dong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-xia","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,20]]},"reference":[{"key":"3577_CR1","first-page":"129","volume":"21","author":"J Jia","year":"2015","unstructured":"Jia J. Status of hand function rehabilitation after stroke. Geriatr Med Health Care (Chin) 2015;21:129\u2013131.","journal-title":"Geriatr Med Health Care (Chin)"},{"key":"3577_CR2","first-page":"229","volume":"34","author":"Z Chen","year":"2019","unstructured":"Chen Z, Liu YG, He X, Li JT, Chen W, Li XH, et al. Research progress of stroke rehabilitation based on data mining technology. Chin J Rehabil Med (Chin) 2019;34:229\u2013233.","journal-title":"Chin J Rehabil Med (Chin)"},{"key":"3577_CR3","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1007\/s11655-021-3338-1","volume":"28","author":"SH Zhang","year":"2022","unstructured":"Zhang SH, Wang YL, Zhang CX, Zhang CP, Xiao P, Li QF, et al. Effect of interactive dynamic scalp acupuncture on post-stroke cognitive function, depression, and anxiety: a multicenter, randomized, controlled trial. Chin J Integr Med 2022;28:106\u2013115.","journal-title":"Chin J Integr Med"},{"key":"3577_CR4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/s11655-019-3079-6","volume":"26","author":"SQ Chen","year":"2020","unstructured":"Chen SQ, Cai DC, Chen JX, Yang H, Liu LS. Altered brain regional homogeneity following contralateral acupuncture at Quchi (LI 11) and Zusanli (ST 36) in ischemic stroke patients with left hemiplegia: an fMRI study. Chin J Integr Med 2020;26:20\u201325.","journal-title":"Chin J Integr Med"},{"key":"3577_CR5","first-page":"1409","volume":"47","author":"JJ Fan","year":"2022","unstructured":"Fan JJ, Li X, Sun HH, Li QE, Wu HC, Ren XQ. Excavation of the connotation of white meridians disease based on Tibetan medical theory and analysis of the composition and usage of Baimai Ointment. China J Tradit Chin Med (Chin) 2022;47:1409\u20131414.","journal-title":"China J Tradit Chin Med (Chin)"},{"key":"3577_CR6","first-page":"370","volume":"19","author":"LJ Zheng","year":"2017","unstructured":"Zheng LJ, Ren XQ, Wang MQ, Mao M, Gao JQ, Zhou ZY, et al. Exploring the rule of the diagnosis and treatment of stroke based on the Tibetan medical theory of white meridian. Modern Tradit Chin Med Mater Med World Sci Technol (Chin) 2017;19:370\u2013374.","journal-title":"Modern Tradit Chin Med Mater Med World Sci Technol (Chin)"},{"key":"3577_CR7","first-page":"69","volume":"23","author":"YM Luo","year":"2017","unstructured":"Luo YM, Ren XQ, Song HR, Xi DJ, Tao XH. Research progress of Tibetan medicine Ruyi Zhenbao Pills in the past 20 years. Chin J Ethn Med (Chin) 2017;23:69\u201372.","journal-title":"Chin J Ethn Med (Chin)"},{"key":"3577_CR8","first-page":"17","volume":"28","author":"J Duo","year":"2009","unstructured":"Duo J, Hu QW. Clinical observation of 219 cases of white meridian (neuropathic pain) treated by Ruyi Zhenbao Pills. Inner Mongol J Tradit Chin Med (Chin) 2009;28:17\u201318.","journal-title":"Inner Mongol J Tradit Chin Med (Chin)"},{"key":"3577_CR9","first-page":"28","volume":"29","author":"HM Wang","year":"2013","unstructured":"Wang HM, Sun H. Observation on clinical efficacy of Ruyi Zhenbao Pills combined with Valaciclovir Tablets on herpes zoster. Shanxi J Tradit Chin Med (Chin) 2013;29:28\u201329.","journal-title":"Shanxi J Tradit Chin Med (Chin)"},{"key":"3577_CR10","first-page":"23","volume":"21","author":"SM Zhai","year":"2015","unstructured":"Zhai SM. Clinical observation on Tibetan medicine Ruyi Zhenbao Pills in the treatment of rheumatoid arthritis. J Med Pharm Chin Minor (Chin) 2015;21:23.","journal-title":"J Med Pharm Chin Minor (Chin)"},{"key":"3577_CR11","first-page":"556","volume":"40","author":"RY Liu","year":"2015","unstructured":"Liu RY, Wu WJ, Tan R, Xie B, Zhong ZD, He JP, et al. Intervention effect of Tibetan patent medicine Ruyi Zhenbao Pills in acute ischemic stroke in rats. China J Chin Mater Med (Chin) 2015;40:556\u2013559.","journal-title":"China J Chin Mater Med (Chin)"},{"key":"3577_CR12","first-page":"1846","volume":"16","author":"B Xie","year":"2014","unstructured":"Xie B, Liu RY, He JP, Tan R. Study on preventing efficacy of combined using of three classical Tibetan prescriptions in focal cerebral ischemia injury of rats. Modern Tradit Chin Med Mater Med World Sci Technol (Chin) 2014;16:1846\u20131849.","journal-title":"Modern Tradit Chin Med Mater Med World Sci Technol (Chin)"},{"key":"3577_CR13","first-page":"413","volume":"16","author":"Duojieladan","year":"2014","unstructured":"Duojieladan, Hong M, Chen QH, Liu YJ, Han M, Sun W. Toxicological study on Tibetan medicine Ruyi Zhenbao Pills. Food Drug (Chin) 2014;16:413\u2013416.","journal-title":"Food Drug (Chin)"},{"key":"3577_CR14","first-page":"60","volume":"29","author":"Chinese Neurology Association","year":"1996","unstructured":"Chinese Neurology Association, Chinese Neurosurgery Association. Key points of diagnosis of various cerebrovascular diseases (1995). Chin J Neurol (Chin) 1996;29:60\u201361.","journal-title":"Chin J Neurol (Chin)"},{"key":"3577_CR15","first-page":"1598","volume":"13","author":"LQ Li","year":"2015","unstructured":"Li LQ, Li CM, Zhao HL, Huang Y, Wei W. Meta-analysis of clinical studies of edaravone combined with Xueshuantong in the treatment of acute cerebral infarction. J Cardiovasc Cerebrovasc Dis Integr Tradit Chin West Med (Chin) 2015;13:1598\u20131604.","journal-title":"J Cardiovasc Cerebrovasc Dis Integr Tradit Chin West Med (Chin)"},{"key":"3577_CR16","first-page":"484","volume":"22","author":"ML Rao","year":"2005","unstructured":"Rao ML. Abstract of guidelines for the prevention and treatment of cerebrovascular diseases in China. J Stroke Neurolog Dis (Chin) 2005;22:484\u2013487.","journal-title":"J Stroke Neurolog Dis (Chin)"},{"key":"3577_CR17","first-page":"55","volume":"4","author":"T Zhang","year":"2012","unstructured":"Zhang T. Guidelines for the rehabilitation of stroke in China. Chin J Front Med (Electr Version, Chin) 2012;4:55\u201376.","journal-title":"Chin J Front Med (Electr Version, Chin)"},{"key":"3577_CR18","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1093\/ptj\/73.7.447","volume":"73","author":"J Sanford","year":"1993","unstructured":"Sanford J, Moreland J, Swanson LR, Stratford PW, Gowland C. Reliability of the Fugl-Meyer assessment for testing motor performance in patients following stroke. Phys Ther 1993;73:447\u2013454.","journal-title":"Phys Ther"},{"key":"3577_CR19","first-page":"503","volume-title":"Neurological rehabilitation evaluation method","author":"YL Wang","year":"2015","unstructured":"Wang YL, ed. Neurological rehabilitation evaluation method. Beijing: People\u2019s Medical Publishing House;2015:503\u2013504."},{"key":"3577_CR20","first-page":"486","volume":"2013","author":"P Giang","year":"2013","unstructured":"Giang P, Williams A, Argyros L. Automated extraction of the Barthel Index from clinical texts. AMIA Annu Symp Proc 2013;2013:486\u2013495.","journal-title":"AMIA Annu Symp Proc"},{"key":"3577_CR21","first-page":"10212","volume":"7","author":"Y Zhao","year":"2013","unstructured":"Zhao Y, Pan YH. Quality of life scale for stroke patients. Chin J Clin (Chin) 2013;7:10212\u201310214.","journal-title":"Chin J Clin (Chin)"},{"key":"3577_CR22","first-page":"24","volume":"18","author":"DM Jin","year":"2003","unstructured":"Jin DM, Yan TB, Zeng HH. A study on the validity and reliability of the Berg Balance Scale. Chin J Rehabil Med (Chin) 2003;18:24\u201326.","journal-title":"Chin J Rehabil Med (Chin)"},{"key":"3577_CR23","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/rheumatology\/15.3.185","volume":"15","author":"EC Huskisson","year":"1976","unstructured":"Huskisson EC, Jone J, Scott PJ. Application of visual analogue scales to the measurement of functional capacity. Rheumatol Rehabil 1976;15:185\u2013187.","journal-title":"Rheumatol Rehabil"},{"key":"3577_CR24","first-page":"1288","volume":"31","author":"LJ Gu","year":"2013","unstructured":"Gu LJ, Zhang JJ. Effect of Ruyi Zhenbao Tablets on the improvement of sequelae of cerebral ischemia in rats. Chin J Tradit Chin Med (Chin) 2013;31:1288\u20131230.","journal-title":"Chin J Tradit Chin Med (Chin)"},{"key":"3577_CR25","first-page":"123","volume-title":"People\u2019s Republic of China Health Ministry of Medicine Standards\u2014Tibetan medicine (volume 1)","author":"Pharmacopoeia Committee of the Ministry of Health, People\u2019s Republic of China","year":"1995","unstructured":"Pharmacopoeia Committee of the Ministry of Health, People\u2019s Republic of China. People\u2019s Republic of China Health Ministry of Medicine Standards\u2014Tibetan medicine (volume 1). Beijing: China Medical Science and Technology Publishing House;1995:123\u2013124."},{"key":"3577_CR26","first-page":"106","volume":"28","author":"ZG Xu","year":"2020","unstructured":"Xu ZG, Bao XH, Tian QJ. A review of research on Ruyi Zhenbao Pills (Tablets). Chin Folk Ther (Chin) 2020;28:106\u2013109.","journal-title":"Chin Folk Ther (Chin)"},{"key":"3577_CR27","first-page":"9","volume":"21","author":"HP Wang","year":"2012","unstructured":"Wang HP, Ma ZY, Li L. Research status of the incidence and treatment of white meridian disease in Tibetan medicine. Chin Ethn Folk Med (Chin) 2012;21:9\u201310.","journal-title":"Chin Ethn Folk Med (Chin)"},{"key":"3577_CR28","first-page":"88","volume":"50","author":"XY Liu","year":"2010","unstructured":"Liu XY, Wang LE, Fu JL. Clinical observation of Ruyi Zhenbao Pills in treating post-stroke sequelae. Shandong Med J (Chin) 2010;50:88.","journal-title":"Shandong Med J (Chin)"},{"key":"3577_CR29","series-title":"Dissertation","volume-title":"Clinical trial of Ruyi Zhenbao Pill in the treatment of motor and sensory dysfunction after stroke","author":"LX Huang","year":"2018","unstructured":"Huang LX. Clinical trial of Ruyi Zhenbao Pill in the treatment of motor and sensory dysfunction after stroke [Dissertation]. Guangzhou: Guangzhou University of Traditional Chinese Medicine;2018."},{"key":"3577_CR30","first-page":"11","volume":"19","author":"XM Wang","year":"2013","unstructured":"Wang XM. Clinical observation of Tibetan medicine Ruyi Zhenbao Pills combined with rehabilitation training in treating hemiplegic shoulder pain. Chin J Ethn Med (Chin) 2013;19:11\u201313.","journal-title":"Chin J Ethn Med (Chin)"},{"key":"3577_CR31","first-page":"556","volume":"40","author":"RY Liu","year":"2015","unstructured":"Liu RY, Wu WJ, Tan R, Xie B, Zhong ZD, He JP, et al. Intervention effect of Tibetan medicine Ruyi Zhenbao Pills on the subacute stage of ischemic stroke in rats. Chin J Tradit Chin Med (Chin) 2015;40:556\u2013559.","journal-title":"Chin J Tradit Chin Med (Chin)"},{"key":"3577_CR32","first-page":"747","volume":"25","author":"X Zhang","year":"2014","unstructured":"Zhang X, Fan LN, Tan R, Li JC, He LL, Gu J. A preliminary comparative study on the rules of cardiovascular medication of three classic Tibetan medicine prescriptions. Lishizhen Med Mater Med Res (Chin) 2014;25:747\u2013748.","journal-title":"Lishizhen Med Mater Med Res (Chin)"},{"key":"3577_CR33","first-page":"307","volume":"40","author":"XY Zhu","year":"2017","unstructured":"Zhu XY, Wang HY, Li HP, Wang HP, Lan XH, Song RS, et al. Ruyi Zhenbao Pill\u2019s protective and regeneration-promoting effects on zebrafish nerve injury. Drug Evaluat Res (Chin) 2017;40:307\u2013313.","journal-title":"Drug Evaluat Res (Chin)"}],"container-title":["Chinese Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-022-3577-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11655-022-3577-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11655-022-3577-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T08:21:18Z","timestamp":1664526078000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11655-022-3577-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,20]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["3577"],"URL":"https:\/\/doi.org\/10.1007\/s11655-022-3577-9","relation":{},"ISSN":["1672-0415","1993-0402"],"issn-type":[{"value":"1672-0415","type":"print"},{"value":"1993-0402","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,20]]},"assertion":[{"value":"30 March 2022","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2022","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}