{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:29:43Z","timestamp":1790141383592,"version":"4.0.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,10,28]],"date-time":"2017-10-28T00:00:00Z","timestamp":1509148800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Osteoporos"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1007\/s11657-017-0387-3","type":"journal-article","created":{"date-parts":[[2017,10,28]],"date-time":"2017-10-28T14:08:44Z","timestamp":1509199724000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Long-term use of angiotensin-converting enzyme inhibitors protects against bone loss in African-American elderly men"],"prefix":"10.1007","volume":"12","author":[{"given":"Nahid","family":"Rianon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine G.","family":"Ambrose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Pervin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scherezade K.","family":"Mama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann V.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,28]]},"reference":[{"key":"387_CR1","unstructured":"National Osteoporosis Foundation (NOF). \nwww.nof.org\n\n. Accessed on 25 Jan 2017"},{"issue":"7","key":"387_CR2","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1089\/jwh.2013.4611","volume":"23","author":"JM Kling","year":"2014","unstructured":"Kling JM, Clarke BL, Sandhu NP (2014) Osteoporosis prevention, screening, and treatment: a review. J Women's Health (Larchmt) 23(7):563\u2013572","journal-title":"J Women's Health (Larchmt)"},{"issue":"6","key":"387_CR3","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.beem.2014.09.003","volume":"28","author":"JY Reginster","year":"2014","unstructured":"Reginster JY, Neuprez A, Dardenne N et al (2014) Efficacy and safety of currently marketed anti-osteoporosis medications. Best Pract Res Clin Endocrinol Metabol 28(6):809\u2013834","journal-title":"Best Pract Res Clin Endocrinol Metabol"},{"issue":"3","key":"387_CR4","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00198-011-1775-y","volume":"23","author":"S Silverman","year":"2012","unstructured":"Silverman S, therapy CCI o (2012) Osteoporos Int 23(3):797\u2013809","journal-title":"Osteoporos Int"},{"key":"387_CR5","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0140-6736(99)01437-3","volume":"354","author":"F Cappuccio","year":"1999","unstructured":"Cappuccio F, Meilahn E, Zmuda JM, Cauley JA, for the Study of Osteoporotic Fractures Research Group (1999) High blood pressure and bone-mineral loss in elderly white women: a prospective study. Lancet 354:971\u2013975","journal-title":"Lancet"},{"key":"387_CR6","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/S0895-7061(01)01303-6","volume":"14","author":"K Tsuda","year":"2001","unstructured":"Tsuda K, Nishio I, Masuyama Y (2001) Bone mineral density in women with essential hypertension. Am J Hypertens 14:704\u2013707","journal-title":"Am J Hypertens"},{"key":"387_CR7","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00223-008-9198-2","volume":"84","author":"P Vestergaard","year":"2009","unstructured":"Vestergaard P, Rejnmark L, Mosekilde L (2009) Hypertension is a risk factor for fractures. Calcif Tissue Int 84:103\u2013111","journal-title":"Calcif Tissue Int"},{"issue":"1","key":"387_CR8","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1677\/joe.0.1520005","volume":"152","author":"R Hatton","year":"1997","unstructured":"Hatton R, Stimpel M, Chambers TJ (1997) Angiotensin II is generated from angiotensin I by bone cells and stimulates osteoclastic bone resorption in vitro. J Endocrinol 152(1):5\u201310","journal-title":"J Endocrinol"},{"key":"387_CR9","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1096\/fj.07-098954","volume":"22","author":"H Shimizu","year":"2008","unstructured":"Shimizu H, Nakagami H, Osako MK et al (2008) Angiotensin II accelerates osteoporosis by activating osteoclasts. FASEB J 22:2465\u20132475","journal-title":"FASEB J"},{"key":"387_CR10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1677\/joe.0.1560543","volume":"156","author":"H Hagiwara","year":"1998","unstructured":"Hagiwara H, Hiruma Y, Inoue A et al (1998) Deceleration by angiotensin II of the differentiation and bone formation of rat calvarial osteoblastic cells. J Endocrinol 156:543\u2013550","journal-title":"J Endocrinol"},{"key":"387_CR11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/(SICI)1097-4652(199804)175:1<89::AID-JCP10>3.0.CO;2-J","volume":"175","author":"S Lamparter","year":"1998","unstructured":"Lamparter S, Kling L, Schrader M et al (1998) Effects of angiotensin II on bone cells in vitro. J Cell Physiol 175:89\u201398","journal-title":"J Cell Physiol"},{"key":"387_CR12","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1271\/bbb.120123","volume":"76","author":"G SS","year":"2012","unstructured":"SS G, Zhang Y, Li XL et al (2012) Involvement of the skeletal renin-angiotensin system in age-related osteoporosis of ageing mice. Biosci Biotechnol Biochem 76:1367\u20131371","journal-title":"Biosci Biotechnol Biochem"},{"issue":"2","key":"387_CR13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1359\/jbmr.081006","volume":"24","author":"Y Asaba","year":"2009","unstructured":"Asaba Y, Ito M, Fumoto T et al (2009) Activation of renin-angiotensin system induces osteoporosis independently of hypertension. J Bone Miner Res 24(2):241\u2013250","journal-title":"J Bone Miner Res"},{"issue":"8","key":"387_CR14","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1074\/jbc.M807610200","volume":"284","author":"Y Izu","year":"2008","unstructured":"Izu Y, Mizoguchi F, Kawamata A et al (2008) Angiotensin II type 2 receptor blockade increases bone mass. J Biol Chem 284(8):4857\u20134864","journal-title":"J Biol Chem"},{"issue":"3","key":"387_CR15","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/01.hjh.0000203845.26690.cb","volume":"24","author":"L Rejnmark","year":"2006","unstructured":"Rejnmark L, Vestergaard P, Mosekilde L (2006) Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case\u2013control study. J Hypertens 24(3):581\u2013589","journal-title":"J Hypertens"},{"issue":"5","key":"387_CR16","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1093\/ageing\/afq071","volume":"39","author":"R Peters","year":"2010","unstructured":"Peters R, Beckett N, Burch L et al (2010) The effect of treatment based on a diuretic (indapamide) \u00b1 ACE inhibitor (perindopril) on fractures in the hypertension in the very elderly trial (HYVET). Age Ageing 39(5):609\u2013616","journal-title":"Age Ageing"},{"key":"387_CR17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.bone.2005.09.011","volume":"38","author":"H Lynn","year":"2006","unstructured":"Lynn H, Kwok T, Wong SYS et al (2006) Angiotensin converting enzyme inhibitor use is associated with higher bone mineral density in elderly Chinese. Bone 38:584\u2013588","journal-title":"Bone"},{"key":"387_CR18","volume-title":"Associations between femur neck BMD and antihypertensive medications affecting renin-angiotensin system in elderly men and women of the Health ABC study. Presented at the Forum on Aging and Skeletal Health","author":"N Rianon","year":"2011","unstructured":"Rianon N, Garcia M, Stotts A et al (2011) Associations between femur neck BMD and antihypertensive medications affecting renin-angiotensin system in elderly men and women of the Health ABC study. Presented at the Forum on Aging and Skeletal Health. Bethesda, MD"},{"issue":"6","key":"387_CR19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0895-7061(03)00845-8","volume":"16","author":"JL Perez-Castrillon","year":"2003","unstructured":"Perez-Castrillon JL, Silva J, Justo I et al (2003) Effect of quinapril, quinapril-hydrochlorothiazide, and enalapril on the bone mass of hypertensive subjects: relationship with angiotensin converting enzyme polymorphisms. Am J Hypertens 16(6):453\u2013459","journal-title":"Am J Hypertens"},{"key":"387_CR20","unstructured":"National Institute on Aging. Health ABC. \nhttps:\/\/www.nia.nih.gov\/research\/intramural-research-program\/dynamics-health-aging-and-body-composition-health-abc\n\n. Accessed on 25 Jan 2017"},{"key":"387_CR21","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s001980050093","volume":"8","author":"AC Looker","year":"1998","unstructured":"Looker AC, Wahner HW, Dunn WL et al (1998) Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int 8:468\u2013489","journal-title":"Osteoporos Int"},{"key":"387_CR22","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1007\/s00198-015-3332-6","volume":"27","author":"D Solomon","year":"2016","unstructured":"Solomon D, Ruppert K, Zhao Z et al (2016) Bone mineral density changes among women initiating blood pressure lowering drugs: a SWAN cohort study. Osteoporos Int 27:1181\u20131189","journal-title":"Osteoporos Int"},{"key":"387_CR23","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1007\/s00198-011-1831-7","volume":"23","author":"T Kwok","year":"2012","unstructured":"Kwok T, Leung J, Zhang YF et al (2012) Does the use of ACE inhibitors or angiotensin receptor blockers affect bone loss in older men? Osteoporos Int 23:2159\u20132167","journal-title":"Osteoporos Int"},{"issue":"6","key":"387_CR24","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1007\/s00774-012-0363-3","volume":"30","author":"YF Zhang","year":"2012","unstructured":"Zhang YF, Qin L, Leung PC et al (2012) The effect of angiotensin-converting enzyme inhibitor use on bone loss in elderly Chinese. J Bone Miner Metab 30(6):666\u2013673","journal-title":"J Bone Miner Metab"},{"key":"387_CR25","first-page":"17","volume":"57","author":"N Masunari","year":"2008","unstructured":"Masunari N, Fujiwara S, Nakata Y et al (2008) Effect of angiotensin-converting enzyme inhibitor and benzodiazepine intake on bone loss in older Japanese. Hiroshima J Med Sci 57:17\u201325","journal-title":"Hiroshima J Med Sci"},{"key":"387_CR26","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s00393-015-1582-5","volume":"74","author":"B Cakmak","year":"2015","unstructured":"Cakmak B, Inanir A, Karakus N et al (2015) Association between the ACE gene I\/D polymorphism and osteoporosis in a Turkish population. Z Rheumatol 74:346\u2013350","journal-title":"Z Rheumatol"},{"key":"387_CR27","doi-asserted-by":"crossref","first-page":"433","DOI":"10.4149\/gpb_2016015","volume":"35","author":"M Allam","year":"2016","unstructured":"Allam M, Hussien N (2016) A comparative study between the effect of 17-\u03b2estradiol and angiotensin converting enzyme inhibitor on osteoporosis in ovariectomized rats. Gen Physiol Biophys 35:433\u2013441","journal-title":"Gen Physiol Biophys"},{"key":"387_CR28","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1053\/ajkd.2000.9688","volume":"36","author":"K Jamerson","year":"2000","unstructured":"Jamerson K (2000) Rationale for angiotensin II receptor blockers in patients with low-renin hypertension. Am J Kidney Dis 36:S24\u2013S30","journal-title":"Am J Kidney Dis"}],"container-title":["Archives of Osteoporosis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11657-017-0387-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11657-017-0387-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11657-017-0387-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T22:25:56Z","timestamp":1515450356000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11657-017-0387-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,28]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["387"],"URL":"https:\/\/doi.org\/10.1007\/s11657-017-0387-3","relation":{},"ISSN":["1862-3522","1862-3514"],"issn-type":[{"value":"1862-3522","type":"print"},{"value":"1862-3514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,28]]},"article-number":"94"}}