{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:09:46Z","timestamp":1790791786551,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T00:00:00Z","timestamp":1575849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T00:00:00Z","timestamp":1575849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Osteoporos"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s11657-019-0663-5","type":"journal-article","created":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T22:06:40Z","timestamp":1575929200000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of risedronate with cholecalciferol on bone mineral density in Korean patients with osteoporosis"],"prefix":"10.1007","volume":"15","author":[{"name":"the IDEAL Trial Investigators","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Young","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo-Il","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung Moo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumie","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Hwan","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Koo","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Min","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Suk","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye Yeon","family":"Won","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye Soo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Soo","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taek Rim","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Cheol","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Yeon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,9]]},"reference":[{"key":"663_CR1","volume-title":"Bone health and osteoporosis","author":"U.S. Department of Health and Human Services","year":"2004","unstructured":"U.S. Department of Health and Human Services (2004) The frequency of bone disease. In: Bone health and osteoporosis"},{"key":"663_CR2","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1016\/j.ecl.2005.07.009","volume":"34","author":"S Khosla","year":"2005","unstructured":"Khosla S, Riggs BL (2005) Pathophysiology of age-related bone loss and osteoporosis. Endocrinol Metab Clin N Am 34:1015\u20131030 xi","journal-title":"Endocrinol Metab Clin N Am"},{"key":"663_CR3","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1097\/01.bor.0000166384.80777.0d","volume":"17","author":"E Dennison","year":"2005","unstructured":"Dennison E, Cole Z, Cooper C (2005) Diagnosis and epidemiology of osteoporosis. Curr Opin Rheumatol 17:456\u2013461","journal-title":"Curr Opin Rheumatol"},{"key":"663_CR4","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1016\/S0140-6736(96)07088-2","volume":"348","author":"DM Black","year":"1996","unstructured":"Black DM, Cummings SR, Karpf DB et al (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348:1535\u20131541","journal-title":"Lancet"},{"key":"663_CR5","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1001\/jama.280.24.2077","volume":"280","author":"SR Cummings","year":"1998","unstructured":"Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, Palermo L, Prineas R, Rubin SM, Scott JC, Vogt T, Wallace R, Yates AJ, LaCroix A (1998) Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA 280:2077\u20132082","journal-title":"JAMA"},{"key":"663_CR6","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1056\/NEJMoa067312","volume":"356","author":"DM Black","year":"2007","unstructured":"Black DM, Delmas PD, Eastell R et al (2007) Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 356:1809\u20131822","journal-title":"N Engl J Med"},{"key":"663_CR7","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1007\/s00223-004-0286-7","volume":"75","author":"DD Mellstrom","year":"2004","unstructured":"Mellstrom DD, Sorensen OH, Goemaere S, Roux C, Johnson TD, Chines AA (2004) Seven years of treatment with risedronate in women with postmenopausal osteoporosis. Calcif Tissue Int 75:462\u2013468","journal-title":"Calcif Tissue Int"},{"key":"663_CR8","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/j.1365-2796.2006.01685.x","volume":"260","author":"P Lips","year":"2006","unstructured":"Lips P, Hosking D, Lippuner K, Norquist JM, Wehren L, Maalouf G, Ragi-Eis S, Chandler J (2006) The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation. J Intern Med 260:245\u2013254","journal-title":"J Intern Med"},{"key":"663_CR9","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.amjmed.2003.12.029","volume":"116","author":"HA Bischoff-Ferrari","year":"2004","unstructured":"Bischoff-Ferrari HA, Dietrich T, Orav EJ, Dawson-Hughes B (2004) Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults. Am J Med 116:634\u2013639","journal-title":"Am J Med"},{"key":"663_CR10","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1359\/jbmr.090826","volume":"25","author":"JA Cauley","year":"2010","unstructured":"Cauley JA, Parimi N, Ensrud KE, Bauer DC, Cawthon PM, Cummings SR, Hoffman AR, Shikany JM, Barrett-Connor E, Orwoll E, Osteoporotic Fractures in Men (MrOS) Research Group (2010) Serum 25-hydroxyvitamin D and the risk of hip and nonspine fractures in older men. J Bone Miner Res 25:545\u2013553","journal-title":"J Bone Miner Res"},{"key":"663_CR11","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1001\/jama.291.16.1999","volume":"291","author":"HA Bischoff-Ferrari","year":"2004","unstructured":"Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, Wong JB (2004) Effect of vitamin D on falls: a meta-analysis. JAMA 291:1999\u20132006","journal-title":"JAMA"},{"key":"663_CR12","doi-asserted-by":"publisher","first-page":"597","DOI":"10.2147\/CIA.S44395","volume":"8","author":"HY Chung","year":"2013","unstructured":"Chung HY, Koo J, Kwon SK, Kang MI, Moon SH, Park JY, Shin CS, Yoon BK, Yoon HK, Chang JS, Chung YS, Park HM (2013) Early changes in 25-hydroxyvitamin D levels and bone markers after monthly risedronate with cholecalciferol in Korean patients with osteoporosis. Clin Interv Aging 8:597\u2013603","journal-title":"Clin Interv Aging"},{"key":"663_CR13","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1111\/j.1365-2265.2011.04041.x","volume":"74","author":"HY Chung","year":"2011","unstructured":"Chung HY, Chin SO, Kang MI, Koh JM, Moon SH, Yoon BK, Yoon HK, Chung YS, Park HM (2011) Efficacy of risedronate with cholecalciferol on 25-hydroxyvitamin D level and bone turnover in Korean patients with osteoporosis. Clin Endocrinol 74:699\u2013704","journal-title":"Clin Endocrinol"},{"key":"663_CR14","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1001\/jama.282.14.1344","volume":"282","author":"ST Harris","year":"1999","unstructured":"Harris ST, Watts NB, Genant HK et al (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA 282:1344\u20131352","journal-title":"JAMA"},{"key":"663_CR15","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1056\/NEJM200102013440503","volume":"344","author":"MR McClung","year":"2001","unstructured":"McClung MR, Geusens P, Miller PD et al (2001) Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med 344:333\u2013340","journal-title":"N Engl J Med"},{"key":"663_CR16","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1359\/jbmr.081214","volume":"24","author":"S Boonen","year":"2009","unstructured":"Boonen S, Orwoll ES, Wenderoth D, Stoner KJ, Eusebio R, Delmas PD (2009) Once-weekly risedronate in men with osteoporosis: results of a 2-year, placebo-controlled, double-blind, multicenter study. J Bone Miner Res 24:719\u2013725","journal-title":"J Bone Miner Res"},{"key":"663_CR17","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s001980050062","volume":"8","author":"L Baeksgaard","year":"1998","unstructured":"Baeksgaard L, Andersen KP, Hyldstrup L (1998) Calcium and vitamin D supplementation increases spinal BMD in healthy, postmenopausal women. Osteoporos Int 8:255\u2013260","journal-title":"Osteoporos Int"},{"key":"663_CR18","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1056\/NEJM199709043371003","volume":"337","author":"B Dawson-Hughes","year":"1997","unstructured":"Dawson-Hughes B, Harris SS, Krall EA, Dallal GE (1997) Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337:670\u2013676","journal-title":"N Engl J Med"},{"key":"663_CR19","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1093\/ajcn\/77.5.1324","volume":"77","author":"L Cooper","year":"2003","unstructured":"Cooper L, Clifton-Bligh PB, Nery ML, Figtree G, Twigg S, Hibbert E, Robinson BG (2003) Vitamin D supplementation and bone mineral density in early postmenopausal women. Am J Clin Nutr 77:1324\u20131329","journal-title":"Am J Clin Nutr"},{"key":"663_CR20","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1359\/jbmr.2000.15.11.2276","volume":"15","author":"D Hunter","year":"2000","unstructured":"Hunter D, Major P, Arden N, Swaminathan R, Andrew T, MacGregor AJ, Keen R, Snieder H, Spector TD (2000) A randomized controlled trial of vitamin D supplementation on preventing postmenopausal bone loss and modifying bone metabolism using identical twin pairs. J Bone Miner Res 15:2276\u20132283","journal-title":"J Bone Miner Res"},{"key":"663_CR21","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1002\/jbmr.5650090702","volume":"9","author":"PJ Elders","year":"1994","unstructured":"Elders PJ, Lips P, Netelenbos JC, van Ginkel FC, Khoe E, van der Vijgh WJ, van der Stelt PF (1994) Long-term effect of calcium supplementation on bone loss in perimenopausal women. J Bone Miner Res 9:963\u2013970","journal-title":"J Bone Miner Res"},{"key":"663_CR22","first-page":"1052","volume":"80","author":"ME Ooms","year":"1995","unstructured":"Ooms ME, Roos JC, Bezemer PD, van der Vijgh WJ, Bouter LM, Lips P (1995) Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial. J Clin Endocrinol Metab 80:1052\u20131058","journal-title":"J Clin Endocrinol Metab"},{"key":"663_CR23","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.pbiomolbio.2006.02.016","volume":"92","author":"P Lips","year":"2006","unstructured":"Lips P (2006) Vitamin D physiology. Prog Biophys Mol Biol 92:4\u20138","journal-title":"Prog Biophys Mol Biol"},{"key":"663_CR24","unstructured":"Cranney A, Horsley T, O\u2019Donnell S et al (2007) Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep):1\u2013235"},{"key":"663_CR25","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3803\/EnM.2015.30.3.272","volume":"30","author":"IJ Cho","year":"2015","unstructured":"Cho IJ, Chung HY, Kim SW, Lee JW, Lee TW, Kim HS, Kim SG, Choi HS, Choi SH, Shin CS, Oh KW, Min YK, Koh JM, Rhee Y, Byun DW, Chung YS, Park JH, Chung DJ, Shong M, Hong EG, Lee CB, Baek KH, Kang MI (2015) Efficacy of a once-monthly pill containing ibandronate and cholecalciferol on the levels of 25-hydroxyvitamin D and bone markers in postmenopausal women with osteoporosis. Endocrinol Metab (Seoul) 30:272\u2013279","journal-title":"Endocrinol Metab (Seoul)"},{"key":"663_CR26","doi-asserted-by":"publisher","first-page":"505","DOI":"10.7326\/0003-4819-115-7-505","volume":"115","author":"B Dawson-Hughes","year":"1991","unstructured":"Dawson-Hughes B, Dallal GE, Krall EA, Harris S, Sokoll LJ, Falconer G (1991) Effect of vitamin D supplementation on wintertime and overall bone loss in healthy postmenopausal women. Ann Intern Med 115:505\u2013512","journal-title":"Ann Intern Med"},{"key":"663_CR27","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1177\/0091270010382010","volume":"51","author":"AE Denker","year":"2011","unstructured":"Denker AE, Lazarus N, Porras A et al (2011) Bioavailability of alendronate and vitamin D(3) in an alendronate\/vitamin D(3) combination tablet. J Clin Pharmacol 51:1439\u20131448","journal-title":"J Clin Pharmacol"}],"container-title":["Archives of Osteoporosis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11657-019-0663-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11657-019-0663-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11657-019-0663-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T09:38:19Z","timestamp":1607506699000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11657-019-0663-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,9]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["663"],"URL":"https:\/\/doi.org\/10.1007\/s11657-019-0663-5","relation":{},"ISSN":["1862-3522","1862-3514"],"issn-type":[{"value":"1862-3522","type":"print"},{"value":"1862-3514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,9]]},"assertion":[{"value":"25 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The institutional review boards of all involved centers approved the study, and informed consent was obtained from all participants.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"3"}}