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PvdB: none. JvdB: received in the past honoraria for lectures or advice from Amgen, Eli-Lilly and UCB and research funding by Eli-Lilly and Amgen. MHEV: received in the past honoraria for lectures or advice from Amgen, Eli-Lilly and UCB. GdK: none. WFL: received in the past honoraria for lectures or advice from Amgen, Eli-Lilly and UCB and research funding by Eli-Lilly and Amgen. EMW: received in the past honoraria for lectures or advice from Amgen, Shire and Lilly. MCZ: received in the past honoraria for lectures or advice from Amgen, Kyowa Kirin, Eli-Lilly, Shire, and UCB. 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