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This simple tool enhances clinical practice by identifying high-risk patients for targeted interventions, potentially preventing or reversing functional decline and recurrent fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate grip strength and hand muscle cross-sectional area as predictors of secondary fracture risk in patients with a history of distal radius fracture (DRF), serving as surrogates of the diagnosis of sarcopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study of 745 DRF patients was analyzed with their grip strength data using Cox proportional hazards regression, receiver operating characteristic analysis, and Kaplan\u2013Meier analysis to predict secondary fracture risk over an average of 12\u00a0years. Hand muscle cross-sectional area was similarly analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with a history of DRF were predicted to have a 4.1% higher likelihood of experiencing a secondary fracture per kilogram reduction in their grip strength (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.008), independent of age and sex. Patients were categorized as high-risk (\u2264\u200916\u00a0kg), moderate-risk (17\u201324\u00a0kg), or low\u2013risk (\u2265\u200925\u00a0kg) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). High-risk patients showed a 2.2-fold (95% CI\u2009=\u20091.55\u20133.17) higher recurrent fracture risk compared to low-risk patients. Cumulative secondary fracture probabilities of the high-risk group patients at 5, 10, and 15\u00a0years were estimated to be 16%, 30%, and 54%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Grip strength measurement, as a surrogate of sarcopenia diagnosis, effectively predicts secondary fracture risk in patients with DRF. This simple tool could improve clinical practice by identifying high-risk patients for targeted interventions to prevent recurrent fractures or even reverse functional decline.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11657-024-01465-5","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T07:27:34Z","timestamp":1737012454000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of using grip strength and hand muscle cross-sectional area to predict secondary fractures post distal radius fracture"],"prefix":"10.1007","volume":"20","author":[{"given":"Matthew Tsz Kin","family":"Kong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3827-0351","authenticated-orcid":false,"given":"Christian","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2624-3441","authenticated-orcid":false,"given":"Colin Shing Yat","family":"Yung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Kwok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5215-1615","authenticated-orcid":false,"given":"Frankie","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"issue":"2","key":"1465_CR1","doi-asserted-by":"publisher","first-page":"169","DOI":"10.14283\/jfa.2022.6","volume":"11","author":"M Yam","year":"2022","unstructured":"Yam M, Ng H, Lim CL, Munro YL, Lim WS (2022) Sarcopenia in distal radius fractures: a scoping review. 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