{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:45:20Z","timestamp":1788583520958,"version":"build-2803163510"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["24FA0601"],"award-info":[{"award-number":["24FA0601"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["24FA1003"],"award-info":[{"award-number":["24FA1003"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004721","name":"The University of Tokyo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004721","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Osteoporos"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>We examined the trends in vitamin D insufficiency and deficiency over a 10-year period in the general population. The prevalence of deficiency significantly decreased (29.5% vs. 21.6%), whereas mean serum levels increased (23.3 ng\/mL vs. 25.1 ng\/mL). These trends may reduce the incidence of osteoporosis and osteoporotic fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>We aimed to clarify the trends in the prevalence of vitamin D insufficiency and deficiency in the general population using population-based cohort data from a baseline survey and a follow-up survey conducted 10\u00a0years later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A baseline survey of the Research on Osteoarthritis\/Osteoporosis Against Disability (ROAD) study was conducted from 2005 to 2007. Blood samples were collected to measure serum 25-hydroxyvitamin D (25D) and intact parathyroid hormone levels from 1,683 participants (595 men, 1,088 women). Participants also completed an interviewer-administered questionnaire, and underwent bone mineral density measurements and radiographic examinations. The fourth survey was conducted from 2015 to 2016 with 1,906 individuals (637 men, 1,269 women), including both follow-up participants from the baseline survey and newly recruited individuals to increase the sample size for future longitudinal analyses. All participants completed assessments identical to those in the baseline survey. Vitamin D deficiency and insufficiency were defined as serum 25D levels of\u2009&lt;\u200920\u00a0ng\/mL and\u2009\u2265\u200920\u00a0ng\/mL but\u2009&lt;\u200930\u00a0ng\/mL, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean serum vitamin D levels were 23.3\u00a0ng\/mL at baseline and 25.1\u00a0ng\/mL at the fourth survey, indicating a significant increase (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The prevalences of vitamin D insufficiency and deficiency were 52.9% and 29.5%, respectively, at baseline, and 54.8% and 21.6%, respectively, in the fourth survey, indicating a significant decrease in vitamin D deficiency (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this population-based survey with a 10-year interval, the prevalence of hypovitaminosis D significantly decreased. This favourable trend may contribute to future reductions in the incidence of osteoporosis and osteoporotic fractures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11657-025-01601-9","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T12:54:19Z","timestamp":1756299259000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Trends in the prevalence of hypovitaminosis D over a 10-year period in Japan: the research on osteoarthritis\/osteoporosis against disability study 2005\u20132015"],"prefix":"10.1007","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9206-4658","authenticated-orcid":false,"given":"Noriko","family":"Yoshimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Iidaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"Horii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaku","family":"Tanegashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeyuki","family":"Muraki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Akune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"key":"1601_CR1","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1210\/edrv.22.4.0437","volume":"22","author":"P Lips","year":"2001","unstructured":"Lips P (2001) Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. 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Several comments intended as author instructions for table formatting were inadvertently included in the published PDF.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2025","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s11657-025-01608-2","URL":"https:\/\/doi.org\/10.1007\/s11657-025-01608-2","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted with the approval of the Ethics Committees of the University of Tokyo (Nos. 1264 and 1326) and University of Wakayama Medical University (No. 373).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All participants provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Consent to participate"}},{"value":"All participants provided informed consent for publication of the results of the ROAD study without any personal information.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Consent for publication"}},{"value":"Noriko Yoshimura, Toshiko Iidaka, Chiaki Horii, Gaku Tanegashima, Shigeyuki Muraki, Hiroyuki Oka, Hiroshi Kawaguchi, Toru Akune, Kozo Nakamura, and Sakae Tanaka declare that they have no conflicts of interest to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"117"}}