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In this cross-sectional study, reduced handgrip strength, calf circumference, and lean mass were associated with higher risk of fracture by FRAX. These easily obtainable parameters may enhance fracture-risk screening in primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To examine the associations between frailty, sarcopenia-related parameters, and fracture risk in community-dwelling older women, and to evaluate whether simple functional measures may help identify individuals at elevated risk of osteoporotic fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study including women aged\u2009\u2265\u200960\u00a0years recruited from a primary care facility in Southern Brazil. Frailty was assessed using the Clinical Frailty Scale, and muscle strength and physical performance were evaluated using SARC-F, Timed Up and Go, gait speed, the Short Physical Performance Battery, calf circumference (CC), and handgrip strength (HGS). Bone mineral density and trabecular bone score (TBS) were measured by DXA. Ten-year fracture probability was estimated using the Brazilian FRAX\u00ae algorithm. Appendicular lean mass index (ALMI) and biochemical markers relevant to bone metabolism were also analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 119 participants, 38.5% were classified as having high or very high 10-year fracture risk. Compared with women in the low-risk group, those at high risk were older and had lower BMI, TBS, HGS, CC, and ALMI, in addition to a higher comorbidity burden. In multivariable Poisson regression adjusted for age and comorbidity, lower muscle strength, reduced muscle mass, and poorer physical performance were independently associated with higher fracture risk prevalence, whereas frailty status was not. Among the muscle parameters, ALMI showed the strongest association with high fracture risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Reduced muscle strength and lean mass were associated with higher fracture risk, even in women without established frailty or sarcopenia. HGS and CC emerge as simple, low-cost indicators that may enhance fracture-risk screening in primary care and complement conventional assessments such as DXA and FRAX.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11657-026-01688-8","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:42:07Z","timestamp":1773880927000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between physical function parameters and fracture risk in older women in primary health care in southern Brazil"],"prefix":"10.1007","volume":"21","author":[{"given":"L\u00e9o Canterle","family":"Dal Osto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana Fioravanti","family":"Roland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u00e1 Nunes","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor Pelegrim","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kawoana Trautman","family":"Vianna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato Gorga Bandeira","family":"de Mello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poli Mara","family":"Spritzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayane Muniz","family":"Fighera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"1688_CR1","unstructured":"World Health Organization (2022) Ageing and health. 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The study protocol was approved by the Ethics Committee of Hospital de Cl\u00ednicas de Porto Alegre (approval number 57139721.3.0000.5327).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"L\u00e9o Canterle Dal Osto, Luana Fioravante Roland, Mari\u00e1 Nunes Pinto, Vitor Pelegrim de Oliveira, Kawoana Trautman Vianna, Renato Gorga Bandeira de Mello, Poli Mara Spritzer and Tayane Muniz Fighera declare that they have no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}],"article-number":"53"}}